JP4307550B2 - 単量体状タンパク質の送達のための方法及び組成物 - Google Patents

単量体状タンパク質の送達のための方法及び組成物 Download PDF

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Publication number
JP4307550B2
JP4307550B2 JP51899697A JP51899697A JP4307550B2 JP 4307550 B2 JP4307550 B2 JP 4307550B2 JP 51899697 A JP51899697 A JP 51899697A JP 51899697 A JP51899697 A JP 51899697A JP 4307550 B2 JP4307550 B2 JP 4307550B2
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Prior art keywords
insulin
multimeric
monomeric
carrier surface
flow path
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Expired - Fee Related
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JP51899697A
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Japanese (ja)
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JP2000502993A5 (enExample
JP2000502993A (ja
Inventor
アントウェルプ，ウィリアム ピー． バン
アントウェルプ，ナネッティ バン
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メドトロニック ミニメッド、 インコーポレイティド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Anesthesiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Medical Informatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP51899697A 1995-11-13 1996-11-12 単量体状タンパク質の送達のための方法及び組成物 Expired - Fee Related JP4307550B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US661195P 1995-11-13 1995-11-13
US60/006,611 1995-11-13
PCT/US1996/018115 WO1997017945A2 (en) 1995-11-13 1996-11-12 Methods and compositions for the delivery of monomeric proteins

Publications (3)

Publication Number Publication Date
JP2000502993A JP2000502993A (ja) 2000-03-14
JP2000502993A5 JP2000502993A5 (enExample) 2004-10-14
JP4307550B2 true JP4307550B2 (ja) 2009-08-05

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Application Number Title Priority Date Filing Date
JP51899697A Expired - Fee Related JP4307550B2 (ja) 1995-11-13 1996-11-12 単量体状タンパク質の送達のための方法及び組成物

Country Status (8)

Country Link
US (1) US5807315A (enExample)
EP (1) EP0861089B1 (enExample)
JP (1) JP4307550B2 (enExample)
AU (1) AU7678196A (enExample)
CA (1) CA2236579C (enExample)
DE (1) DE69622421T2 (enExample)
DK (1) DK0861089T3 (enExample)
WO (1) WO1997017945A2 (enExample)

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Also Published As

Publication number Publication date
AU7678196A (en) 1997-06-05
WO1997017945A2 (en) 1997-05-22
DE69622421D1 (de) 2002-08-22
EP0861089A2 (en) 1998-09-02
CA2236579A1 (en) 1997-05-22
JP2000502993A (ja) 2000-03-14
WO1997017945A3 (en) 1997-07-10
CA2236579C (en) 2009-06-30
EP0861089B1 (en) 2002-07-17
DE69622421T2 (de) 2003-03-20
DK0861089T3 (da) 2002-10-07
US5807315A (en) 1998-09-15

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