JP4293292B2 - トランスフェクション活性を有するインテグリン−ターゲッティングベクター - Google Patents
トランスフェクション活性を有するインテグリン−ターゲッティングベクター Download PDFInfo
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
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| PCT/GB1998/001577 WO1998054347A1 (en) | 1997-05-29 | 1998-05-29 | Integrin-targeting vectors having transfection activity |
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| JP2002502243A JP2002502243A (ja) | 2002-01-22 |
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| EP1178117A1 (en) * | 2000-08-02 | 2002-02-06 | Erasmus Universiteit Rotterdam | Targeting through integrins |
| NO20004795D0 (no) | 2000-09-26 | 2000-09-26 | Nycomed Imaging As | Peptidbaserte forbindelser |
| US8613907B2 (en) * | 2000-10-12 | 2013-12-24 | University Of Rochester | Compositions that inhibit proliferation of cancer cells |
| GB0106315D0 (en) | 2001-03-14 | 2001-05-02 | Ich Productions Ltd | Transfection complexes |
| RU2294192C2 (ru) * | 2001-05-30 | 2007-02-27 | Дзе Скриппс Рисерч Инститьют | Система доставки нуклеиновых кислот |
| BRPI0210886B8 (pt) | 2001-07-10 | 2021-05-25 | Amersham Health As | composto, composição farmacêutica, uso de um composto, e, métodos de geração de imagens, de monitoração do efeito do tratamento de um corpo humano ou animal com uma droga para combater uma condição associada com câncer e de tratamento de câncer ou de uma doença relacionada em um corpo humano ou animal |
| US7598421B2 (en) | 2002-05-08 | 2009-10-06 | Ucl Biomedica Plc | Materials for the delivery of biologically-active material to cells |
| GB0210538D0 (en) * | 2002-05-08 | 2002-06-19 | Univ London | Lipids and gene delivery |
| AU2004233873B2 (en) * | 2003-04-25 | 2010-11-18 | The Penn State Research Foundation | Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds |
| GB0313132D0 (en) * | 2003-06-06 | 2003-07-09 | Ich Productions Ltd | Peptide ligands |
| US20090123468A1 (en) | 2003-10-24 | 2009-05-14 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| US8507277B2 (en) | 2003-10-24 | 2013-08-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides |
| US8062891B2 (en) | 2003-10-24 | 2011-11-22 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to plants |
| CA2543257C (en) | 2003-10-24 | 2013-12-31 | Gencia Corporation | Methods and compositions for delivering polynucleotides |
| US8133733B2 (en) | 2003-10-24 | 2012-03-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to target tissues |
| WO2007089871A2 (en) * | 2006-02-01 | 2007-08-09 | The Johns Hopkins University | Polypeptide-nucleic acid conjugate for immunoprophylaxis or immunotherapy for neoplastic or infectious disorders |
| US10034674B2 (en) * | 2006-02-02 | 2018-07-31 | Steven C Chudik | Universal anterior cruciate ligament repair and reconstruction system |
| GB0610636D0 (en) * | 2006-05-30 | 2006-07-05 | Univ London | Materials and complexes for the delivery of biologically-active material to cells |
| RU2010107199A (ru) * | 2007-07-31 | 2011-09-10 | Дзе Джонс Хопкинс Юниверсити (Us) | Конъюгат полипептид-нуклеиновая кислота для иммунопрофилактики или иммунотерапии для неопластических или инфекционных нарушений |
| KR101863136B1 (ko) | 2008-01-24 | 2018-05-31 | 에스퍼란스 파마슈티컬스, 인코포레이티드 | 용해 도메인 융합 구성물 및 이를 제조하고 사용하는 방법 |
| US20110256055A1 (en) | 2008-12-23 | 2011-10-20 | Ge Healthcare Limited | Application of 99mtc peptide-based compound as a bone marrow imaging agent |
| CN118271422A (zh) | 2015-08-28 | 2024-07-02 | 分子传递有限公司 | 转染络合物和其使用方法 |
| EP3423438A4 (en) | 2016-03-01 | 2020-05-06 | Molecular Transfer, Inc. | PLANT VIRUS MOTOR PROTEINS AND METHOD FOR USE THEREOF |
| GB201604235D0 (en) | 2016-03-11 | 2016-04-27 | Ucl Business Plc | Lipids and complexes for the delivery of biologically-active material to cells |
| GB201803419D0 (en) * | 2018-03-02 | 2018-04-18 | Ucl Business Plc | Complex for the delivery of cas9 proteins guide RNA to cells |
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| AU3876695A (en) | 1994-11-17 | 1996-06-17 | Imperial College Of Science, Technology And Medicine | Internalisation of dna, using conjugates of poly-l-lysine and an integrin receptor ligand |
| EP0874910A4 (en) | 1995-06-07 | 1999-04-21 | Life Technologies Inc | ENHANCED CATIONIC LIPID TRANSFECTION BY PEPTIDES |
| US5908777A (en) | 1995-06-23 | 1999-06-01 | University Of Pittsburgh | Lipidic vector for nucleic acid delivery |
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- 1998-05-29 CA CA002288840A patent/CA2288840A1/en not_active Abandoned
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- 1998-05-29 JP JP55077198A patent/JP4293292B2/ja not_active Expired - Fee Related
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2002
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| EP1003898A1 (en) | 2000-05-31 |
| US20020042384A1 (en) | 2002-04-11 |
| US20030013644A1 (en) | 2003-01-16 |
| AU7667398A (en) | 1998-12-30 |
| DE69831156D1 (de) | 2005-09-15 |
| ATE301722T1 (de) | 2005-08-15 |
| EP1003898B1 (en) | 2005-08-10 |
| JP2002502243A (ja) | 2002-01-22 |
| DE69831156T2 (de) | 2006-06-08 |
| GB9711115D0 (en) | 1997-07-23 |
| CA2288840A1 (en) | 1998-12-03 |
| WO1998054347A1 (en) | 1998-12-03 |
| US6458026B1 (en) | 2002-10-01 |
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