GB9711115D0 - Integrin-targeting vectors having enhanced transfection activity - Google Patents
Integrin-targeting vectors having enhanced transfection activityInfo
- Publication number
- GB9711115D0 GB9711115D0 GBGB9711115.7A GB9711115A GB9711115D0 GB 9711115 D0 GB9711115 D0 GB 9711115D0 GB 9711115 A GB9711115 A GB 9711115A GB 9711115 D0 GB9711115 D0 GB 9711115D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- integrin
- transfection activity
- targeting vectors
- enhanced transfection
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000001890 transfection Methods 0.000 title abstract 2
- 239000013598 vector Substances 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 102000006495 integrins Human genes 0.000 abstract 1
- 108010044426 integrins Proteins 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000002502 liposome Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
- Y10S977/907—Liposome
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compression Or Coding Systems Of Tv Signals (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Electrotherapy Devices (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9711115.7A GB9711115D0 (en) | 1997-05-29 | 1997-05-29 | Integrin-targeting vectors having enhanced transfection activity |
| AT98924478T ATE301722T1 (de) | 1997-05-29 | 1998-05-29 | Integrin-zielvektoren mit transfektionaktivität |
| DE69831156T DE69831156T2 (de) | 1997-05-29 | 1998-05-29 | Integrin-zielvektoren mit transfektionaktivität |
| JP55077198A JP4293292B2 (ja) | 1997-05-29 | 1998-05-29 | トランスフェクション活性を有するインテグリン−ターゲッティングベクター |
| PCT/GB1998/001577 WO1998054347A1 (en) | 1997-05-29 | 1998-05-29 | Integrin-targeting vectors having transfection activity |
| US09/424,656 US6458026B1 (en) | 1997-05-29 | 1998-05-29 | Integrin-targeting vectors having transfection activity |
| CA002288840A CA2288840A1 (en) | 1997-05-29 | 1998-05-29 | Integrin-targeting vectors having transfection activity |
| AU76673/98A AU7667398A (en) | 1997-05-29 | 1998-05-29 | Integrin-targeting vectors having transfection activity |
| EP98924478A EP1003898B1 (en) | 1997-05-29 | 1998-05-29 | Integrin-targeting vectors having transfection activity |
| US10/137,435 US20030013644A1 (en) | 1997-05-29 | 2002-05-03 | Integrin-targeting vectors having transfection activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9711115.7A GB9711115D0 (en) | 1997-05-29 | 1997-05-29 | Integrin-targeting vectors having enhanced transfection activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB9711115D0 true GB9711115D0 (en) | 1997-07-23 |
Family
ID=10813246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB9711115.7A Pending GB9711115D0 (en) | 1997-05-29 | 1997-05-29 | Integrin-targeting vectors having enhanced transfection activity |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6458026B1 (https=) |
| EP (1) | EP1003898B1 (https=) |
| JP (1) | JP4293292B2 (https=) |
| AT (1) | ATE301722T1 (https=) |
| AU (1) | AU7667398A (https=) |
| CA (1) | CA2288840A1 (https=) |
| DE (1) | DE69831156T2 (https=) |
| GB (1) | GB9711115D0 (https=) |
| WO (1) | WO1998054347A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2405469C (en) | 2000-04-12 | 2012-03-20 | Amersham Health As | Integrin binding peptide derivatives |
| AU2001260467A1 (en) * | 2000-05-30 | 2001-12-11 | Ich Productions Limited | Integrin-targeting vectors having enhanced transfection activity |
| EP1178117A1 (en) * | 2000-08-02 | 2002-02-06 | Erasmus Universiteit Rotterdam | Targeting through integrins |
| NO20004795D0 (no) | 2000-09-26 | 2000-09-26 | Nycomed Imaging As | Peptidbaserte forbindelser |
| US8613907B2 (en) * | 2000-10-12 | 2013-12-24 | University Of Rochester | Compositions that inhibit proliferation of cancer cells |
| GB0106315D0 (en) | 2001-03-14 | 2001-05-02 | Ich Productions Ltd | Transfection complexes |
| RU2294192C2 (ru) * | 2001-05-30 | 2007-02-27 | Дзе Скриппс Рисерч Инститьют | Система доставки нуклеиновых кислот |
| BRPI0210886B8 (pt) | 2001-07-10 | 2021-05-25 | Amersham Health As | composto, composição farmacêutica, uso de um composto, e, métodos de geração de imagens, de monitoração do efeito do tratamento de um corpo humano ou animal com uma droga para combater uma condição associada com câncer e de tratamento de câncer ou de uma doença relacionada em um corpo humano ou animal |
| US7598421B2 (en) | 2002-05-08 | 2009-10-06 | Ucl Biomedica Plc | Materials for the delivery of biologically-active material to cells |
| GB0210538D0 (en) * | 2002-05-08 | 2002-06-19 | Univ London | Lipids and gene delivery |
| AU2004233873B2 (en) * | 2003-04-25 | 2010-11-18 | The Penn State Research Foundation | Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds |
| GB0313132D0 (en) * | 2003-06-06 | 2003-07-09 | Ich Productions Ltd | Peptide ligands |
| US20090123468A1 (en) | 2003-10-24 | 2009-05-14 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| US8507277B2 (en) | 2003-10-24 | 2013-08-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides |
| US8062891B2 (en) | 2003-10-24 | 2011-11-22 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to plants |
| CA2543257C (en) | 2003-10-24 | 2013-12-31 | Gencia Corporation | Methods and compositions for delivering polynucleotides |
| US8133733B2 (en) | 2003-10-24 | 2012-03-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to target tissues |
| WO2007089871A2 (en) * | 2006-02-01 | 2007-08-09 | The Johns Hopkins University | Polypeptide-nucleic acid conjugate for immunoprophylaxis or immunotherapy for neoplastic or infectious disorders |
| US10034674B2 (en) * | 2006-02-02 | 2018-07-31 | Steven C Chudik | Universal anterior cruciate ligament repair and reconstruction system |
| GB0610636D0 (en) * | 2006-05-30 | 2006-07-05 | Univ London | Materials and complexes for the delivery of biologically-active material to cells |
| RU2010107199A (ru) * | 2007-07-31 | 2011-09-10 | Дзе Джонс Хопкинс Юниверсити (Us) | Конъюгат полипептид-нуклеиновая кислота для иммунопрофилактики или иммунотерапии для неопластических или инфекционных нарушений |
| KR101863136B1 (ko) | 2008-01-24 | 2018-05-31 | 에스퍼란스 파마슈티컬스, 인코포레이티드 | 용해 도메인 융합 구성물 및 이를 제조하고 사용하는 방법 |
| US20110256055A1 (en) | 2008-12-23 | 2011-10-20 | Ge Healthcare Limited | Application of 99mtc peptide-based compound as a bone marrow imaging agent |
| CN118271422A (zh) | 2015-08-28 | 2024-07-02 | 分子传递有限公司 | 转染络合物和其使用方法 |
| EP3423438A4 (en) | 2016-03-01 | 2020-05-06 | Molecular Transfer, Inc. | PLANT VIRUS MOTOR PROTEINS AND METHOD FOR USE THEREOF |
| GB201604235D0 (en) | 2016-03-11 | 2016-04-27 | Ucl Business Plc | Lipids and complexes for the delivery of biologically-active material to cells |
| GB201803419D0 (en) * | 2018-03-02 | 2018-04-18 | Ucl Business Plc | Complex for the delivery of cas9 proteins guide RNA to cells |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981478A (en) | 1993-11-24 | 1999-11-09 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
| AU3876695A (en) | 1994-11-17 | 1996-06-17 | Imperial College Of Science, Technology And Medicine | Internalisation of dna, using conjugates of poly-l-lysine and an integrin receptor ligand |
| EP0874910A4 (en) | 1995-06-07 | 1999-04-21 | Life Technologies Inc | ENHANCED CATIONIC LIPID TRANSFECTION BY PEPTIDES |
| US5908777A (en) | 1995-06-23 | 1999-06-01 | University Of Pittsburgh | Lipidic vector for nucleic acid delivery |
-
1997
- 1997-05-29 GB GBGB9711115.7A patent/GB9711115D0/en active Pending
-
1998
- 1998-05-29 WO PCT/GB1998/001577 patent/WO1998054347A1/en not_active Ceased
- 1998-05-29 DE DE69831156T patent/DE69831156T2/de not_active Expired - Lifetime
- 1998-05-29 CA CA002288840A patent/CA2288840A1/en not_active Abandoned
- 1998-05-29 AT AT98924478T patent/ATE301722T1/de not_active IP Right Cessation
- 1998-05-29 EP EP98924478A patent/EP1003898B1/en not_active Expired - Lifetime
- 1998-05-29 US US09/424,656 patent/US6458026B1/en not_active Expired - Lifetime
- 1998-05-29 AU AU76673/98A patent/AU7667398A/en not_active Abandoned
- 1998-05-29 JP JP55077198A patent/JP4293292B2/ja not_active Expired - Fee Related
-
2002
- 2002-05-03 US US10/137,435 patent/US20030013644A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1003898A1 (en) | 2000-05-31 |
| US20020042384A1 (en) | 2002-04-11 |
| US20030013644A1 (en) | 2003-01-16 |
| AU7667398A (en) | 1998-12-30 |
| DE69831156D1 (de) | 2005-09-15 |
| ATE301722T1 (de) | 2005-08-15 |
| EP1003898B1 (en) | 2005-08-10 |
| JP2002502243A (ja) | 2002-01-22 |
| DE69831156T2 (de) | 2006-06-08 |
| JP4293292B2 (ja) | 2009-07-08 |
| CA2288840A1 (en) | 1998-12-03 |
| WO1998054347A1 (en) | 1998-12-03 |
| US6458026B1 (en) | 2002-10-01 |
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