JP4194233B2 - シース液供給装置および供給方法並びに試料分析装置 - Google Patents

シース液供給装置および供給方法並びに試料分析装置 Download PDF

Info

Publication number
JP4194233B2
JP4194233B2 JP2000248689A JP2000248689A JP4194233B2 JP 4194233 B2 JP4194233 B2 JP 4194233B2 JP 2000248689 A JP2000248689 A JP 2000248689A JP 2000248689 A JP2000248689 A JP 2000248689A JP 4194233 B2 JP4194233 B2 JP 4194233B2
Authority
JP
Japan
Prior art keywords
sheath
cylinder
piston
flow cell
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2000248689A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002062250A (ja
JP2002062250A5 (enExample
Inventor
正治 芝田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sysmex Corp
Original Assignee
Sysmex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sysmex Corp filed Critical Sysmex Corp
Priority to JP2000248689A priority Critical patent/JP4194233B2/ja
Priority to US09/930,967 priority patent/US20020020207A1/en
Publication of JP2002062250A publication Critical patent/JP2002062250A/ja
Priority to US10/336,789 priority patent/US6804984B2/en
Priority to US10/336,790 priority patent/US20030110826A1/en
Publication of JP2002062250A5 publication Critical patent/JP2002062250A5/ja
Application granted granted Critical
Publication of JP4194233B2 publication Critical patent/JP4194233B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01PMEASURING LINEAR OR ANGULAR SPEED, ACCELERATION, DECELERATION, OR SHOCK; INDICATING PRESENCE, ABSENCE, OR DIRECTION, OF MOVEMENT
    • G01P21/00Testing or calibrating of apparatus or devices covered by the preceding groups
    • G01P21/02Testing or calibrating of apparatus or devices covered by the preceding groups of speedometers
    • G01P21/025Testing or calibrating of apparatus or devices covered by the preceding groups of speedometers for measuring speed of fluids; for measuring speed of bodies relative to fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0636Focussing flows, e.g. to laminate flows
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652Sorting or classification of particles or molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409Handling samples, e.g. injecting samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
JP2000248689A 2000-08-18 2000-08-18 シース液供給装置および供給方法並びに試料分析装置 Expired - Lifetime JP4194233B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000248689A JP4194233B2 (ja) 2000-08-18 2000-08-18 シース液供給装置および供給方法並びに試料分析装置
US09/930,967 US20020020207A1 (en) 2000-08-18 2001-08-17 Sheath liquid supplying apparatus, sheath liquid supplying method, and evaluating method of sheath liquid supplying condition
US10/336,789 US6804984B2 (en) 2000-08-18 2003-01-06 Sheath liquid supplying apparatus, sheath liquid supplying method, and evaluating method of sheath liquid supplying condition
US10/336,790 US20030110826A1 (en) 2000-08-18 2003-01-06 Sheath liquid supplying apparatus, sheath liquid supplying method, and evaluating method of sheath liquid supplying condition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000248689A JP4194233B2 (ja) 2000-08-18 2000-08-18 シース液供給装置および供給方法並びに試料分析装置

Publications (3)

Publication Number Publication Date
JP2002062250A JP2002062250A (ja) 2002-02-28
JP2002062250A5 JP2002062250A5 (enExample) 2005-11-04
JP4194233B2 true JP4194233B2 (ja) 2008-12-10

Family

ID=18738550

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000248689A Expired - Lifetime JP4194233B2 (ja) 2000-08-18 2000-08-18 シース液供給装置および供給方法並びに試料分析装置

Country Status (2)

Country Link
US (3) US20020020207A1 (enExample)
JP (1) JP4194233B2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1348943A3 (en) * 2002-03-25 2003-12-17 Sysmex Corporation Sheath liquid for particle analyzer
KR101166180B1 (ko) * 2003-08-13 2012-07-18 루미넥스 코포레이션 유세포 분석기식 측정 시스템의 하나 이상의 파라미터의 제어 방법
JP4027872B2 (ja) * 2003-10-03 2007-12-26 シスメックス株式会社 シースフロー形成装置およびそれを備えた試料分析装置
CN102494985A (zh) * 2011-12-26 2012-06-13 山东兰桥医学科技有限公司 一种小型负压装置
US10022720B2 (en) 2015-06-12 2018-07-17 Cytochip Inc. Fluidic units and cartridges for multi-analyte analysis
US10634602B2 (en) 2015-06-12 2020-04-28 Cytochip Inc. Fluidic cartridge for cytometry and additional analysis
CN108027310B (zh) 2015-07-14 2020-12-22 芯易诊有限公司 流体盒中的体积感测
CN110234442A (zh) * 2016-11-19 2019-09-13 厦泰生物科技公司 具有步进流量控制阀的流式细胞术系统
WO2019000459A1 (zh) * 2017-06-30 2019-01-03 深圳迈瑞生物医疗电子股份有限公司 供液装置、样本分析仪及供液方法
BR102018075954A2 (pt) * 2017-09-15 2019-11-12 Horiba Ltd aparelho de análise de partículas
US11491487B2 (en) 2017-10-23 2022-11-08 Cytochip Inc. Devices and methods for measuring analytes and target particles
CN111751265A (zh) * 2020-06-30 2020-10-09 深圳市科曼医疗设备有限公司 一种鞘流液路系统及控制方法
CN115963050B (zh) * 2023-03-16 2023-07-21 赛默飞世尔(上海)仪器有限公司 鞘液供应系统、流式细胞仪及用于供应鞘液的方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3788744A (en) * 1970-01-14 1974-01-29 Bio Physics Systems Inc Method and apparatus for photoanalysis
US3831618A (en) * 1972-12-22 1974-08-27 Abbott Lab Apparatus for the precision metering of fluids
US4111051A (en) * 1975-02-20 1978-09-05 Bodenseewerk Perkin-Elmer & Co., Gmbh Sampling procedure and device for flameless atomic absorption spectroscopy
US4476734A (en) * 1983-03-07 1984-10-16 International Business Machines Corporation Wet needle sampler for use with a gas chromatograph
US4736732A (en) * 1985-09-03 1988-04-12 Olympus Optical Co., Ltd. Endoscopic fluid changing device
US5215714A (en) 1988-04-08 1993-06-01 Toa Medical Electronics Co., Ltd. Immunoagglutination measurement apparatus
JPH0353164A (ja) * 1989-07-20 1991-03-07 Canon Inc サンプル供給装置及びこれを用いたサンプル測定装置
JP2808321B2 (ja) * 1989-09-19 1998-10-08 東亜医用電子株式会社 細胞分析方法及び装置
JP2965688B2 (ja) * 1990-11-30 1999-10-18 シスメックス株式会社 粒子検出装置
JP3075367B2 (ja) 1991-04-05 2000-08-14 シスメックス株式会社 粒子分析方法及び装置
JP3115641B2 (ja) * 1991-04-24 2000-12-11 シスメックス株式会社 粒子計数方法
US5603700A (en) 1993-12-27 1997-02-18 Daneshvar; Yousef Suction and injection system
JP3158929B2 (ja) 1995-01-27 2001-04-23 株式会社日立製作所 粒子分析装置
JP2001059839A (ja) 1995-10-16 2001-03-06 Takeda Chem Ind Ltd 自動精製装置
SE507956C2 (sv) * 1996-11-20 1998-08-03 Medonic Ab Utspädnings- och mätanordning för partikelräkning
JP3681252B2 (ja) 1997-03-18 2005-08-10 シスメックス株式会社 粒子計数方法および粒子計数装置
JP2000214070A (ja) * 1999-01-21 2000-08-04 Sysmex Corp シ―スフロ―セルとそれを用いた血液分析装置

Also Published As

Publication number Publication date
JP2002062250A (ja) 2002-02-28
US20020020207A1 (en) 2002-02-21
US20030110826A1 (en) 2003-06-19
US6804984B2 (en) 2004-10-19
US20030107725A1 (en) 2003-06-12

Similar Documents

Publication Publication Date Title
JP4194233B2 (ja) シース液供給装置および供給方法並びに試料分析装置
CN101262950B (zh) 流量计量分析器
Ṙuz̆ic̆ka et al. Flow injection analyses: Part I. A new concept of fast continuous flow analysis
US8361410B2 (en) Flow metered analyzer
US6197494B1 (en) Apparatus for performing assays on liquid samples accurately, rapidly and simply
JP5159845B2 (ja) 粒子分析装置
US20210096055A1 (en) Linear resitance stepper flow control valve for sheath fluid of flow cytometry systems
US6473171B1 (en) Biocompatible apparatus for ultrasensitive and rapid detection of contaminants in liquids
EP1812799B1 (en) Apparatus and method for processing biological liquids
JP2009521684A (ja) 携帯用サンプル分析装置のカートリッジ
CN101275962A (zh) 试样分析仪及试样分析方法
CN102288519B (zh) 用于估算粘度的方法
KR102546374B1 (ko) 적혈구 침강 속도 및 다른 연결된 파라미터를 결정하기 위한 장치 및 방법
CN104737025A (zh) 用于生物化学传感器的流动管道系统
US7389679B2 (en) Measurement cell and method for the analysis of liquids
JP4744264B2 (ja) 尿中有形成分分析装置用標準物質。
JPH08114601A (ja) 液体検体の多項目検査分析装置
KR200331884Y1 (ko) 혈액 점도와 혈구 응집률을 동시에 측정하는 장치
Lee et al. Absorbent-force-driven microflow cytometer
JP4096242B2 (ja) 表面プラズモン共鳴測定装置
KR20230054407A (ko) 성분분석용 h-형 필터장치
US20220178811A1 (en) Opto-Fluidic Apparatus for Individual Interrogation of Organisms
US20250264406A1 (en) Infrared transmission cell with attached flow sensor for microfluidic modulation spectroscopy
WO2025132566A1 (en) Measuring arrangement and method for analyzing a fluidic sample
US20230221241A1 (en) Optical flow cell for bioprocessing

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050818

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20050818

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20060213

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20080902

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20080922

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

Ref document number: 4194233

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20111003

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20141003

Year of fee payment: 6

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term