JP4115502B2 - 流体分配装置 - Google Patents
流体分配装置 Download PDFInfo
- Publication number
- JP4115502B2 JP4115502B2 JP2006523317A JP2006523317A JP4115502B2 JP 4115502 B2 JP4115502 B2 JP 4115502B2 JP 2006523317 A JP2006523317 A JP 2006523317A JP 2006523317 A JP2006523317 A JP 2006523317A JP 4115502 B2 JP4115502 B2 JP 4115502B2
- Authority
- JP
- Japan
- Prior art keywords
- fluid
- assembly
- receiving
- distribution system
- fluid distribution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000012530 fluid Substances 0.000 title claims description 127
- 238000010438 heat treatment Methods 0.000 claims description 6
- 230000000712 assembly Effects 0.000 claims description 5
- 238000000429 assembly Methods 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 20
- 239000007788 liquid Substances 0.000 description 8
- 230000003139 buffering effect Effects 0.000 description 4
- 238000004891 communication Methods 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 230000004913 activation Effects 0.000 description 2
- 239000003570 air Substances 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 238000013016 damping Methods 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical group [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229910000831 Steel Chemical group 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 239000000696 magnetic material Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 230000009972 noncorrosive effect Effects 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 239000010959 steel Chemical group 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0265—Drop counters; Drop formers using valves to interrupt or meter fluid flow, e.g. using solenoids or metering valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
- G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
- G01F11/021—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1002—Reagent dispensers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0605—Metering of fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0666—Solenoid valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0203—Burettes, i.e. for withdrawing and redistributing liquids through different conduits
- B01L3/0206—Burettes, i.e. for withdrawing and redistributing liquids through different conduits of the plunger pump type
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/112499—Automated chemical analysis with sample on test slide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Fluid Mechanics (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Sampling And Sample Adjustment (AREA)
- Loading And Unloading Of Fuel Tanks Or Ships (AREA)
Description
本発明は、医療研究所用の流体分配デバイスおよび関連するシステムに関する。
生物学的な試験を行うときに、液体(例えば、試薬)を組織標本を含む試験スライド上に分配することがしばしば必要である。例えば腫瘍組織を分析する場合、薄くスライスされた組織の切片がスライド上に配置され得、そして所定の量の液体試薬を組織の上に分配する工程を含む、種々の工程を通して処理され得る。自動化された試薬流体分配デバイスは、一連のあらかじめ選ばれた試薬を、試験スライドに正確に適用するために開発されてきた。
本発明は、少量の流体を正確に分配し得、そして必要に応じて、複数の流体分配カートリッジを操作する関連する流体分配システム操作と一緒に作動する流体分配カートリッジを提供することによって、公知の流体分配装置の、上記および他の欠点を大幅に解決する。
以下の段落において、本発明は、添付の図面を参照して、例として詳細に記載される。本明細書全体にわたって、示される好ましい実施形態および実施例は、本発明の限定としてではなく、例とみなされるべきである。本明細書中において使用される場合、「本発明」とは、本明細書中に記載される実施形態の任意の1つ、および任意の均等物をいう。さらに、本明細書全体にわたる、「本発明」の種々の特徴に関する言及は、全ての本願実施形態または方法が、参照される特徴を含まなければならないことを意味しない。
Claims (18)
- 流体分配システム(400)であって、該システムは、以下:
複数の流体分配カートリッジ取り付けステーション(420)を有する、直線的に移動可能な取り付けアセンブリ(410)であって、該移動可能な取り付けアセンブリ(410)がまた、直線的に移動可能な回転軸の周りで回転可能である、移動可能な取り付けアセンブリ(410);および
該取り付けアセンブリ(410)の下に配置される受け入れアセンブリ(440)であって、該受け入れアセンブリ(440)は、その頂部表面に複数の受け入れ部材(450)位置を備える、受け入れアセンブリ、
を備える、流体分配システム(400)。 - 前記受け入れ部材位置のそれぞれに、少なくとも1つの受け入れ部材(450)をさらに備える、請求項1に記載の流体分配システム(400)。
- 前記受け入れ部材(450)がトレーである、請求項2に記載の流体分配システム(400)。
- 前記少なくとも1つの受け入れ部材がそれぞれ、顕微鏡スライドを受け入れるのに適した構造を備える、請求項2に記載の流体分配システム(400)。
- 前記少なくとも1つの受け入れ部材がそれぞれ、流体受け入れ表面を備える、請求項2に記載の流体分配システム(400)。
- 前記受け入れ部材(450)位置が、前記受け入れアセンブリ(440)の表面上に直線的に並べられる、請求項1に記載の流体分配システム(400)。
- 前記受け入れ部材(450)位置が、前記受け入れアセンブリ(440)の表面上に少なくとも2列(510、520、530)で並べられ、そして前記取り付けアセンブリ(410)が該列(510、520、530)の上を直線的に移動可能である、請求項1に記載の流体分配システム(400)。
- 複数の前記受け入れ部材(450)位置に位置している加熱要素(460)をさらに備える、請求項1に記載の流体分配システム(400)。
- 前記加熱要素(460)が、異なる受け入れ部材(450)を加熱するために選択的に制御される、請求項8に記載の流体分配システム(400)。
- 前記加熱要素(460)が、ばね付勢された加熱パッドを備える、請求項8に記載の流体分配システム(400)。
- 前記受け入れアセンブリ(440)の前記頂部表面の下に、少なくとも1つの流体供給容器(550)位置をさらに備える、請求項1に記載の流体分配システム(400)。
- 前記少なくとも1つの流体供給容器位置と前記頂部表面とのそれぞれの間に配置される、少なくとも1つの弁(570)をさらに備える、請求項11に記載の流体分配システム(400)。
- 前記受け入れアセンブリ(440)の前記頂部表面の下に配置される、少なくとも1つの排出容器(560)位置をさらに備える、請求項1に記載の流体分配システム(400)。
- 流体分配システム(400)であって、該システムは、以下:
頂部表面および該頂部表面上の複数の受け入れ部材(450)位置を備える、受け入れアセンブリ(440);
複数の流体分配カートリッジ取り付けステーション(420)をその上に有する、直線的に移動可能な取り付けアセンブリ(410)であって、該移動可能な取り付けアセンブリ(410)がまた、直線的に移動可能な回転軸の周りで回転可能である、移動可能な取り付けアセンブリ(410);
複数の作動装置アセンブリ(480、490、500)であって、該作動装置アセンブリの少なくとも1つが、該流体分配カートリッジ取り付けステーション(420)のそれぞれに対応する、作動装置アセンブリ;および
該作動装置アセンブリ(480、490、500)のそれぞれと通信するコントローラーであって、該コントローラーが、該作動装置アセンブリ(480、490、500)を作動させて、それぞれの該カートリッジ取り付けステーション(420)に取り付けられたカートリッジ(10)から流体を分配する、コントローラー、
を備える、流体分配システム(400)。 - 流体分配システム(400)であって、該システムは、以下:
複数の流体分配カートリッジ取り付けステーション(420)を有する、可動な取り付けアセンブリ(410)であって、該取り付けアセンブリ(410)が直線的に移動可能であり、かつ直線的に移動可能な回転軸の周りで回転可能である、可動な取り付けアセンブリ(410);および
該取り付けアセンブリ(410)の下に配置される実質的に静止している受け入れアセンブリ(440)であって、該受け入れアセンブリ(440)が、その頂部表面に複数の受け入れ部材(450)位置を備える、受け入れアセンブリ、
を備える、流体分配システム(400)。 - 顕微鏡スライド上に取り付けられたサンプルに流体を分配する方法であって、該方法は、以下:
複数の顕微鏡スライドを、それぞれのトレー(450)上に各1枚配置する工程;
それぞれの該トレーを、受け入れアセンブリ(440)上に直線的に並べて配置する工程;
流体分配カートリッジ(10)を直線的および回転的に移動可能な取り付けアセンブリ(410)上に取り付ける工程;
該取り付けアセンブリ(410)を直線的および回転的に移動して、該流体分配カートリッジ(10)を選択された該トレー(450)の1つの上に配置する工程;および
流体を分配する工程、
を包含する、方法。 - 請求項1に記載の流体分配システム(400)であって、該システムは、以下:
前記受け入れアセンブリ(440)の前記頂部表面の下の、少なくとも1つの流体供給容器(550)位置;および
該受け入れアセンブリ(440)の該頂部表面の下に配置される、少なくとも1つの排出容器(560)位置、
をさらに備える、流体分配システム(400)。 - 前記少なくとも1つの流体供給容器位置または前記少なくとも1つの排出容器位置のうちの少なくとも1つと、前記頂部表面との間に配置される、少なくとも1つの弁(570)、
をさらに備える、請求項17に記載の流体分配システム(400)。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/639,021 US7501283B2 (en) | 2003-08-11 | 2003-08-11 | Fluid dispensing apparatus |
PCT/US2004/025960 WO2005019092A2 (en) | 2003-08-11 | 2004-08-11 | Fluid dispensing apparatus |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007508525A JP2007508525A (ja) | 2007-04-05 |
JP4115502B2 true JP4115502B2 (ja) | 2008-07-09 |
Family
ID=34135789
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006523317A Active JP4115502B2 (ja) | 2003-08-11 | 2004-08-11 | 流体分配装置 |
Country Status (10)
Country | Link |
---|---|
US (1) | US7501283B2 (ja) |
EP (1) | EP1663847B9 (ja) |
JP (1) | JP4115502B2 (ja) |
CN (1) | CN1976868B (ja) |
AU (1) | AU2004266226B2 (ja) |
BR (1) | BRPI0413515B1 (ja) |
CA (1) | CA2535376C (ja) |
DK (1) | DK1663847T3 (ja) |
ES (1) | ES2609903T3 (ja) |
WO (1) | WO2005019092A2 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011137693A (ja) * | 2009-12-28 | 2011-07-14 | Tosoh Corp | 液体容器およびそれを用いた自動分注装置 |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7468161B2 (en) | 2002-04-15 | 2008-12-23 | Ventana Medical Systems, Inc. | Automated high volume slide processing system |
US11249095B2 (en) | 2002-04-15 | 2022-02-15 | Ventana Medical Systems, Inc. | Automated high volume slide processing system |
US7767152B2 (en) | 2003-08-11 | 2010-08-03 | Sakura Finetek U.S.A., Inc. | Reagent container and slide reaction retaining tray, and method of operation |
US9518899B2 (en) * | 2003-08-11 | 2016-12-13 | Sakura Finetek U.S.A., Inc. | Automated reagent dispensing system and method of operation |
US7744817B2 (en) * | 2003-08-11 | 2010-06-29 | Sakura Finetek U.S.A., Inc. | Manifold assembly |
GB2413498B (en) * | 2004-04-27 | 2008-06-25 | Bespak Plc | Dispensing apparatus |
GB0424313D0 (en) * | 2004-11-03 | 2004-12-01 | Imi Norgren Ltd | Liquid dispensing system |
US8153061B2 (en) * | 2005-11-23 | 2012-04-10 | Siemens Healthcare Diagnostics Inc. | Storage and supply system for clinical solutions used in an automatic analyzer |
US8459509B2 (en) | 2006-05-25 | 2013-06-11 | Sakura Finetek U.S.A., Inc. | Fluid dispensing apparatus |
EP2362228B1 (en) * | 2007-07-10 | 2013-09-18 | Ventana Medical Systems, Inc. | Apparatus and method for biological sample processing |
WO2009152569A1 (en) * | 2008-06-16 | 2009-12-23 | Leica Biosystems Melbourne Pty Ltd | Improvements in staining instruments and methods |
EP2163901A1 (de) * | 2008-09-10 | 2010-03-17 | Roche Diagnostics GmbH | Verfahren und Dosiereinrichtung zum Dosieren einer Flüssigkeit in einen Aufnahmekanal eines Testelementes zur Analyse von Körperflüssigkeiten |
CN102209889B (zh) | 2008-11-12 | 2015-05-13 | 文塔纳医疗系统公司 | 用于加热载持标本的载玻片的方法及设备 |
US10746752B2 (en) | 2009-11-13 | 2020-08-18 | Ventana Medical Systems, Inc. | Opposables and automated specimen processing systems with opposables |
DE102010000690A1 (de) | 2010-01-05 | 2011-07-07 | Hamilton Bonaduz Ag | Dosiervorrichtung und Dosierverfahren |
JP5494014B2 (ja) * | 2010-03-01 | 2014-05-14 | 東ソー株式会社 | 分注ポンプおよびそれを備えた液体容器 |
EP2374541A1 (en) * | 2010-04-06 | 2011-10-12 | Symbion Medical Systems Sàrl | Disposable dispensing cartridge for medical assay instrumentation |
ES2699950T3 (es) | 2010-10-06 | 2019-02-13 | Biocare Medical Llc | Procedimiento y sistema para el procesamiento eficaz de muestras biológicas |
CN105115798B (zh) * | 2010-11-09 | 2018-02-02 | 艾博生物医药(杭州)有限公司 | 一种处理样本的方法 |
ES2700297T3 (es) | 2010-11-10 | 2019-02-14 | Roche Diagnostics Hematology Inc | Aparato automático para preparar muestras biológicas para examinar |
US8752732B2 (en) * | 2011-02-01 | 2014-06-17 | Sakura Finetek U.S.A., Inc. | Fluid dispensing system |
US9945763B1 (en) | 2011-02-18 | 2018-04-17 | Biocare Medical, Llc | Methods and systems for immunohistochemistry heat retrieval of biological samples |
US10143984B2 (en) * | 2011-03-28 | 2018-12-04 | Fast & Fluid Management B.V. | Method and apparatus for dispensing liquids from a plurality of cartridges |
ES2797448T3 (es) | 2011-08-01 | 2020-12-02 | Bio Rad Laboratories | Sistema de captura de células |
US8580568B2 (en) | 2011-09-21 | 2013-11-12 | Sakura Finetek U.S.A., Inc. | Traceability for automated staining system |
US8932543B2 (en) | 2011-09-21 | 2015-01-13 | Sakura Finetek U.S.A., Inc. | Automated staining system and reaction chamber |
EP2662138A1 (en) * | 2012-05-08 | 2013-11-13 | Roche Diagniostics GmbH | Microfluidic dispenser, cartridge and analysis system for analyzing a biological sample |
EP2662671B1 (en) * | 2012-05-08 | 2018-03-28 | Roche Diagniostics GmbH | Cartridge for dispensing a fluid |
AU2013370567B2 (en) * | 2012-12-26 | 2016-05-26 | Ventana Medical Systems, Inc. | Specimen processing systems and methods for preparing reagents |
US11274998B2 (en) | 2012-12-26 | 2022-03-15 | Ventana Medical Systems, Inc. | Specimen processing systems and methods for holding slides |
US9989448B2 (en) | 2012-12-26 | 2018-06-05 | Ventana Medical Systems, Inc. | Specimen processing systems and methods for holding slides |
AU2014248018A1 (en) | 2013-04-05 | 2015-08-20 | Roche Diagnostics Hematology, Inc. | Automated systems and methods for preparing biological specimens for examination |
EP3747545A1 (en) * | 2013-07-25 | 2020-12-09 | Siemens Healthcare Diagnostics Inc. | Reagent dispensers, dispensing apparatus, and methods |
CN111089980B (zh) | 2013-12-13 | 2023-08-15 | 文塔纳医疗系统公司 | 生物样本的自动化组织学处理及相关的技术 |
CA2981975C (en) | 2015-04-06 | 2023-08-01 | Nanocytomics, LLC | Automated specimen deposition systems and associated methods |
US9987655B2 (en) * | 2015-06-26 | 2018-06-05 | Tokyo Electron Limited | Inline dispense capacitor system |
US10758908B2 (en) * | 2015-09-03 | 2020-09-01 | Tetracore, Inc. | Self-metering of fluid into a reaction chamber |
US10399840B2 (en) * | 2016-04-19 | 2019-09-03 | Pepsico, Inc. | Beverage dispensing valve system |
US11460383B2 (en) | 2016-06-16 | 2022-10-04 | Nanocytomics, LLC | Automated staining system |
EP3600692A4 (en) * | 2017-03-20 | 2020-11-11 | Liqui-Box Corporation | PUMP-TYPE DISTRIBUTION MECHANISM INTENDED FOR FLUID PRODUCT PACKAGING |
EP3607087A4 (en) | 2017-04-04 | 2020-12-30 | Omniome, Inc. | FLUIDIC APPARATUS AND USEFUL METHODS FOR CHEMICAL AND BIOLOGICAL REACTIONS |
CN111295245B (zh) | 2017-08-29 | 2021-03-16 | 伯乐实验室有限公司 | 用于分离和分析细胞的系统和方法 |
US11958091B2 (en) | 2018-04-19 | 2024-04-16 | Ecolab Usa Inc. | Fluid delivery devices, systems, and methods |
US10633693B1 (en) | 2019-04-16 | 2020-04-28 | Celsee Diagnostics, Inc. | System and method for leakage control in a particle capture system |
CA3138881A1 (en) | 2019-05-07 | 2020-11-12 | Bio-Rad Laboratories, Inc. | System and method for automated single cell processing |
US11273439B2 (en) | 2019-05-07 | 2022-03-15 | Bio-Rad Laboratories, Inc. | System and method for target material retrieval from microwells |
KR102056055B1 (ko) * | 2019-07-11 | 2019-12-16 | 코리아바이오엔지니어링 주식회사 | 샘플 채취용 밸브 어셈블리 |
EP4036032A4 (en) * | 2019-09-25 | 2023-10-18 | Kao Corporation | DONOR |
US11504719B2 (en) | 2020-03-12 | 2022-11-22 | Bio-Rad Laboratories, Inc. | System and method for receiving and delivering a fluid for sample processing |
IT202100013469A1 (it) * | 2021-05-25 | 2022-11-25 | Starscaspe 4D S R L | Testina di stampa 3D per stampare tessuti biologici e relativo sistema di stampa 3D. |
Family Cites Families (118)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2709025A (en) | 1953-03-30 | 1955-05-24 | Scott Thomas Willard | Dispenser for measured quantity of paste |
US3294290A (en) | 1965-04-06 | 1966-12-27 | Dole Valve Co | Valve assembly controlling flow into, and discharge from, a fluid measuring chamber |
US4149633A (en) | 1974-04-26 | 1979-04-17 | Kenova Ab | Two-chamber package |
US3904079A (en) * | 1974-09-30 | 1975-09-09 | Neely George B | Mixed drink preparation apparatus |
IT1022669B (it) | 1974-10-07 | 1978-04-20 | Macchi Cassia Antonio | Distributore particolarmente per sapone liquido |
US4039775A (en) | 1975-10-01 | 1977-08-02 | Fisher Scientific Company | Uniform temperature incubator |
US4099483A (en) | 1976-04-07 | 1978-07-11 | Shandon Southern Products Limited | Tissue processing apparatus |
US4199558A (en) | 1976-04-07 | 1980-04-22 | Shandon Southern Products Limited | Tissue processing method |
US4258759A (en) * | 1979-03-29 | 1981-03-31 | Achen John J | Turntable for colorant dispensers |
US4356727A (en) | 1980-03-07 | 1982-11-02 | Brown Carole E | Continuous volume measuring system |
DE77477T1 (de) | 1981-10-20 | 1984-10-25 | Shandon Southern Products Ltd., Runcorn, Cheshire | Geraet zur behandlung von gewebe. |
EP0190169B1 (de) | 1984-08-23 | 1988-03-23 | Hafina Treufinanz Ag | Behälter mit einem verschluss |
US4764342A (en) | 1985-02-27 | 1988-08-16 | Fisher Scientific Company | Reagent handling |
US4741898A (en) | 1985-04-01 | 1988-05-03 | Fisher Scientific Company | Stabilized stain composition |
IT1208551B (it) | 1985-05-20 | 1989-07-10 | Steiner Co Int Sa | Erogatore perfezionato di sapone liquido e relativa cartuccia di alimentazione. |
US4731335A (en) | 1985-09-13 | 1988-03-15 | Fisher Scientific Company | Method for treating thin samples on a surface employing capillary flow |
US4678752A (en) | 1985-11-18 | 1987-07-07 | Becton, Dickinson And Company | Automatic random access analyzer |
US4784577A (en) | 1986-09-02 | 1988-11-15 | Critikon, Inc. | Pump pressure sensor |
US4848596A (en) * | 1986-10-14 | 1989-07-18 | The Coca-Cola Company | Disposable syrup package having integral disposable valve assembly |
GB8628371D0 (en) | 1986-11-27 | 1986-12-31 | Shandon Southern Prod | Tissue specimen treatment apparatus |
GB8629982D0 (en) | 1986-12-16 | 1987-01-28 | English Glass Co Ltd | Dispenser pump |
EP0276097A3 (en) | 1987-01-22 | 1989-11-15 | Splicerite Limited | Liquid container |
US5002736A (en) | 1987-03-31 | 1991-03-26 | Fisher Scientific Co. | Microscope slide and slide assembly |
GB8722902D0 (en) | 1987-09-30 | 1987-11-04 | Shandon Southern Prod | Tissue &c processing |
DE3733354A1 (de) | 1987-10-02 | 1989-04-13 | Bramlage Gmbh | Spender fuer pastoese massen |
CH675216A5 (ja) | 1987-11-30 | 1990-09-14 | Alphasem Ag | |
JPH01126474U (ja) | 1988-02-22 | 1989-08-29 | ||
US4927061A (en) | 1988-09-22 | 1990-05-22 | The Meyer Company | Dispensing valve with elastic sealing tube |
US4978036A (en) | 1988-11-15 | 1990-12-18 | Koller Enterprises, Inc. | Dispensing valve |
US4921136A (en) | 1988-11-29 | 1990-05-01 | Inopak Ltd. | Fixture for bag-type liquid dispenser |
US4972978A (en) | 1988-12-13 | 1990-11-27 | Georgia-Pacific Corporation | Dispenser having an improved metering chamber |
US5035350A (en) | 1989-02-21 | 1991-07-30 | Minnesota Mining And Manufacturing Company | Method and apparatus for precision squeeze tube valving, pumping and dispensing of work fluid(s) |
US5033656A (en) | 1989-02-21 | 1991-07-23 | Minnesota Mining And Manufacturing Company | Method and apparatus for precision squeeze tube valving, pumping and dispensing of work fluid (s) |
US4961508A (en) | 1989-06-12 | 1990-10-09 | Restaurant Technology, Inc. | Condiment dispenser with pivotable arm |
US4969581A (en) | 1989-08-08 | 1990-11-13 | The Procter & Gamble Company | Unequivocal bottom delivery container with self-sealing valve |
US5225325A (en) | 1990-03-02 | 1993-07-06 | Ventana Medical Systems, Inc. | Immunohistochemical staining method and reagents therefor |
US5595707A (en) | 1990-03-02 | 1997-01-21 | Ventana Medical Systems, Inc. | Automated biological reaction apparatus |
US6472217B1 (en) | 1990-03-02 | 2002-10-29 | Ventana Medical Systems, Inc. | Slide aqueous volume controlling apparatus |
US5114047A (en) | 1990-08-14 | 1992-05-19 | Lykes Pasco Inc. | Pump and mixing device for liquids |
US5244787A (en) | 1991-01-31 | 1993-09-14 | Biogenex Laboratories | Antigen retrieval in formalin-fixed tissues using microwave energy |
US5696887A (en) | 1991-08-05 | 1997-12-09 | Biotek Solutions, Incorporated | Automated tissue assay using standardized chemicals and packages |
US5355439A (en) | 1991-08-05 | 1994-10-11 | Bio Tek Instruments | Method and apparatus for automated tissue assay |
US5232664A (en) | 1991-09-18 | 1993-08-03 | Ventana Medical Systems, Inc. | Liquid dispenser |
US5578452A (en) | 1992-01-16 | 1996-11-26 | Biogenex Laboratories | Enhancement of immunochemical staining in aldehyde-fixed tissues |
US5242083A (en) | 1992-01-27 | 1993-09-07 | Inpaco Corporation | Liquid dispensing system having a liquid reservoir |
JP3320444B2 (ja) | 1992-04-06 | 2002-09-03 | 株式会社千代田製作所 | 染色装置用ノズル洗浄装置 |
JP3193443B2 (ja) | 1992-04-24 | 2001-07-30 | オリンパス光学工業株式会社 | 自動分析装置 |
US5433351A (en) | 1992-05-01 | 1995-07-18 | Misuzuerie Co., Ltd. | Controlled liquid dispensing apparatus |
US6092695A (en) | 1992-05-11 | 2000-07-25 | Cytologix Corporation | Interchangeable liquid dispensing cartridge pump |
US5645114A (en) | 1992-05-11 | 1997-07-08 | Cytologix Corporation | Dispensing assembly with interchangeable cartridge pumps |
US5316452A (en) | 1992-05-11 | 1994-05-31 | Gilbert Corporation | Dispensing assembly with interchangeable cartridge pumps |
US5947167A (en) | 1992-05-11 | 1999-09-07 | Cytologix Corporation | Dispensing assembly with interchangeable cartridge pumps |
US6180061B1 (en) | 1992-05-11 | 2001-01-30 | Cytologix Corporation | Moving platform slide stainer with heating elements |
US5356039A (en) | 1992-12-15 | 1994-10-18 | Inpaco Corporation | Pump tube and pouch |
SE501740C2 (sv) | 1993-06-04 | 1995-05-02 | Billy Nilson | Självstängande förslutningsanordning för utmatning av flytbar substans, innefattande ett flexibelt membran vilket är försett med deformationszoner |
US5439649A (en) | 1993-09-29 | 1995-08-08 | Biogenex Laboratories | Automated staining apparatus |
US6632598B1 (en) * | 1994-03-11 | 2003-10-14 | Biogenex Laboratories | Deparaffinization compositions and methods for their use |
US6451551B1 (en) | 1994-03-11 | 2002-09-17 | Biogenex Laboratories | Releasing embedding media from tissue specimens |
US5580523A (en) | 1994-04-01 | 1996-12-03 | Bard; Allen J. | Integrated chemical synthesizers |
US6076583A (en) | 1994-07-19 | 2000-06-20 | Fisher Scientific Company | Automated slide staining system |
US6387326B1 (en) | 1994-07-19 | 2002-05-14 | Fisher Scientific Company L.L.C. | Automated slide staining system and method thereof |
US6355166B1 (en) * | 1994-08-25 | 2002-03-12 | The University Of Iowa Research Foundation | Magnetically enhanced composite materials and methods for making and using the same |
JP3398749B2 (ja) | 1994-11-10 | 2003-04-21 | オーキッド バイオ サイエンシズ, インコーポレイテッド | 液体分配システム |
US5954167A (en) | 1995-03-01 | 1999-09-21 | Ricor Racing & Development, L.P. | Flow sensitive acceleration sensitive shock absorber with added flow control |
US5626262A (en) | 1995-06-07 | 1997-05-06 | Redmond Products, Inc. | Dispensing container with drainage passages |
US5609822A (en) | 1995-07-07 | 1997-03-11 | Ciba Corning Diagnostics Corp. | Reagent handling system and reagent pack for use therein |
IT240441Y1 (it) * | 1996-02-09 | 2001-04-02 | Italtinto Srl | Macchina dosatrice in particolare per coloranti |
US5958342A (en) * | 1996-05-17 | 1999-09-28 | Incyte Pharmaceuticals, Inc. | Jet droplet device |
US5839091A (en) | 1996-10-07 | 1998-11-17 | Lab Vision Corporation | Method and apparatus for automatic tissue staining |
US6735531B2 (en) | 1996-10-07 | 2004-05-11 | Lab Vision Corporation | Method and apparatus for automatic tissue staining |
US5810204A (en) | 1996-10-15 | 1998-09-22 | James River Corporation | Apparatus for dispensing liquid soap or other liquids |
US5855302A (en) | 1996-12-18 | 1999-01-05 | Georgia-Pacific Corporation | Liquid dispensing cap valve assembly with pedestal mounted resilient valve seal element |
GB9701930D0 (en) | 1997-01-30 | 1997-03-19 | Life Sciences Int Europe | Tissue processing apparatus and method |
US5948359A (en) | 1997-03-21 | 1999-09-07 | Biogenex Laboratories | Automated staining apparatus |
DE19734375C1 (de) | 1997-08-08 | 1999-02-11 | Stabilus Gmbh | Kolben-Zylinderaggregat mit einem Kolben, der einen Toleranzausgleich aufweist |
US20050135972A1 (en) * | 1997-08-11 | 2005-06-23 | Ventana Medical Systems, Inc. | Method and apparatus for modifying pressure within a fluid dispenser |
US6192945B1 (en) | 1997-08-11 | 2001-02-27 | Ventana Medical Systems, Inc. | Fluid dispenser |
US6045759A (en) | 1997-08-11 | 2000-04-04 | Ventana Medical Systems | Fluid dispenser |
US6093574A (en) | 1997-08-11 | 2000-07-25 | Ventana Medical Systems | Method and apparatus for rinsing a microscope slide |
US6582962B1 (en) | 1998-02-27 | 2003-06-24 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
US6296809B1 (en) | 1998-02-27 | 2001-10-02 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
US6096271A (en) | 1998-02-27 | 2000-08-01 | Cytologix Corporation | Random access slide stainer with liquid waste segregation |
US6183693B1 (en) * | 1998-02-27 | 2001-02-06 | Cytologix Corporation | Random access slide stainer with independent slide heating regulation |
US6855559B1 (en) * | 1998-09-03 | 2005-02-15 | Ventana Medical Systems, Inc. | Removal of embedding media from biological samples and cell conditioning on automated staining instruments |
US6495106B1 (en) | 1998-03-24 | 2002-12-17 | Biogenex Laboratories | Automated staining apparatus |
EP1930078A1 (en) * | 1998-05-01 | 2008-06-11 | Gen-Probe Incorporated | Method for agitating the contents of a container |
DE69935230T2 (de) | 1998-08-10 | 2007-12-20 | Genomic Solutions, Inc., Ann Arbor | Vorrichtung für thermische und flüssige zirkulation zur hybridierung von nukleinsäuren |
US6855552B2 (en) * | 1998-09-03 | 2005-02-15 | Ventana Medical Systems | Automated immunohistochemical and in situ hybridization assay formulations |
FR2784968B1 (fr) | 1998-10-23 | 2000-12-01 | Oreal | Embout doseur et recipient equipe d'un embout doseur selon l'invention |
US6544798B1 (en) | 1999-02-26 | 2003-04-08 | Ventana Medical Systems, Inc. | Removal of embedding media from biological samples and cell conditioning on automated staining instruments |
US6673620B1 (en) | 1999-04-20 | 2004-01-06 | Cytologix Corporation | Fluid exchange in a chamber on a microscope slide |
DE19918442B4 (de) | 1999-04-23 | 2005-04-14 | Leica Microsystems Nussloch Gmbh | Färbeautomat zum Einfärben von Objekten zur mikroskopischen Untersuchung |
GB9912977D0 (en) | 1999-06-04 | 1999-08-04 | Crown Cork & Seal Tech Corp | Closure with dispensing valve |
US6216916B1 (en) | 1999-09-16 | 2001-04-17 | Joseph S. Kanfer | Compact fluid pump |
US6758360B2 (en) * | 1999-12-23 | 2004-07-06 | Royal Packaging Industry Leer N.V. | Pallet container with grid support structure |
US6746851B1 (en) * | 2000-01-14 | 2004-06-08 | Lab Vision Corporation | Method for automated staining of specimen slides |
US6273298B1 (en) * | 2000-03-08 | 2001-08-14 | Fluid Management, Inc. | Apparatus for dispensing viscous fluids from flexible packages and holder for such packages |
US20030100043A1 (en) * | 2000-03-24 | 2003-05-29 | Biogenex Laboratories, Inc. | Device and methods for automated specimen processing |
DE10015773A1 (de) | 2000-03-30 | 2001-10-04 | Leica Mikrosysteme Gmbh Wien | Probenhalter für wasserhaltige Präparate und Verfahren zu dessen Verwendung sowie Hochdruckgefriereinrichtung für den Probenhalter |
US6419663B2 (en) * | 2000-05-18 | 2002-07-16 | John E. Harrold | Mechanically propelled, metered liquid dispenser |
FR2809712B1 (fr) | 2000-05-30 | 2002-07-26 | Oreal | Embout doseur pour la distribution d'une dose a volume variable et ensemble equipe d'un tel embout doseur |
DE10065143B4 (de) * | 2000-12-23 | 2007-12-27 | Leica Mikrosysteme Gmbh | Probenhalter für eine Hochdruckgefriereinrichtung |
US6580056B1 (en) | 2001-09-21 | 2003-06-17 | Biocare Medical | Biological specimen heating device and quality control method for immunohistochemistry heat retrieval procedures |
GB0122801D0 (en) * | 2001-09-21 | 2001-11-14 | Thermo Shandon Ltd | Tissue projector with integrated valve |
JP3701594B2 (ja) * | 2001-09-25 | 2005-09-28 | 日本碍子株式会社 | 液滴吐出方法 |
US20040033163A1 (en) * | 2001-11-26 | 2004-02-19 | Lab Vision Corporation | Automated tissue staining system and reagent container |
US6998270B2 (en) * | 2001-11-26 | 2006-02-14 | Lab Vision Corporation | Automated tissue staining system and reagent container |
CA2492064C (en) * | 2002-06-20 | 2016-03-15 | Vision Biosystems Limited | Biological reaction apparatus with draining mechanism |
JP2005533255A (ja) * | 2002-07-16 | 2005-11-04 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | 自動化された組織化学処理用トレイ |
DE10258104B4 (de) * | 2002-12-11 | 2005-11-03 | Leica Mikrosysteme Gmbh | Präparathalter mit Entnahmehilfe für die Mikrotomie und die AFM-Mikroskopie |
US7875245B2 (en) * | 2003-05-14 | 2011-01-25 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
US7648678B2 (en) * | 2002-12-20 | 2010-01-19 | Dako Denmark A/S | Method and system for pretreatment of tissue slides |
US7007824B2 (en) * | 2003-01-24 | 2006-03-07 | Baxter International Inc. | Liquid dispenser and flexible bag therefor |
AU2003900810A0 (en) * | 2003-02-24 | 2003-03-13 | Vision Biosystems Limited | Method of scheduling |
CA2528584A1 (en) * | 2003-06-09 | 2005-01-06 | Dako Denmark A/S | Diaphram metering chamber dispensing systems |
EP1697719B1 (en) * | 2003-12-23 | 2018-09-19 | Ventana Medical Systems, Inc. | Method and apparatus for efficient thin film fluid processing of flat surfaces |
EP1771716A4 (en) * | 2004-06-29 | 2012-04-25 | Dako Denmark As | METHOD FOR PRE-TREATING AND STAINING A CARRIER DEVICE FOR A BIOLOGICAL SAMPLE |
US7867443B2 (en) * | 2004-07-23 | 2011-01-11 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
-
2003
- 2003-08-11 US US10/639,021 patent/US7501283B2/en not_active Expired - Lifetime
-
2004
- 2004-08-11 DK DK04780745.8T patent/DK1663847T3/en active
- 2004-08-11 CA CA002535376A patent/CA2535376C/en active Active
- 2004-08-11 CN CN2004800256671A patent/CN1976868B/zh active Active
- 2004-08-11 JP JP2006523317A patent/JP4115502B2/ja active Active
- 2004-08-11 WO PCT/US2004/025960 patent/WO2005019092A2/en active Application Filing
- 2004-08-11 EP EP04780745.8A patent/EP1663847B9/en active Active
- 2004-08-11 AU AU2004266226A patent/AU2004266226B2/en active Active
- 2004-08-11 BR BRPI0413515-6A patent/BRPI0413515B1/pt active IP Right Grant
- 2004-08-11 ES ES04780745.8T patent/ES2609903T3/es active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011137693A (ja) * | 2009-12-28 | 2011-07-14 | Tosoh Corp | 液体容器およびそれを用いた自動分注装置 |
Also Published As
Publication number | Publication date |
---|---|
US20050035156A1 (en) | 2005-02-17 |
AU2004266226B2 (en) | 2007-11-22 |
BRPI0413515B1 (pt) | 2019-04-02 |
CN1976868A (zh) | 2007-06-06 |
DK1663847T3 (en) | 2017-01-30 |
CN1976868B (zh) | 2011-07-27 |
AU2004266226A1 (en) | 2005-03-03 |
EP1663847A4 (en) | 2011-03-02 |
BRPI0413515A2 (pt) | 2015-01-20 |
CA2535376C (en) | 2009-04-14 |
US7501283B2 (en) | 2009-03-10 |
JP2007508525A (ja) | 2007-04-05 |
EP1663847B9 (en) | 2017-09-27 |
EP1663847B1 (en) | 2016-11-09 |
WO2005019092A3 (en) | 2006-11-02 |
ES2609903T3 (es) | 2017-04-25 |
EP1663847A2 (en) | 2006-06-07 |
CA2535376A1 (en) | 2005-03-03 |
WO2005019092A2 (en) | 2005-03-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4115502B2 (ja) | 流体分配装置 | |
CA2652898C (en) | Fluid dispensing apparatus | |
US5439649A (en) | Automated staining apparatus | |
US5948359A (en) | Automated staining apparatus | |
EP2555000B1 (en) | Discharge device and liquid dispensing device, and method for dispensing liquid | |
EP2944940B1 (en) | Aid for filling liquid, and method for filling liquid | |
WO2010074915A2 (en) | Evaporation mitigation for slide staining apparatus | |
BR102012008059B1 (pt) | Cartucho, sistema e método de dispensação de fluido | |
US10941875B2 (en) | Valve comprising a variable flow opening | |
US10252273B2 (en) | Valve for dispensing a fluid | |
JP3860267B2 (ja) | 精密容量の生物学的流体を分配する装置 | |
PT109305A (pt) | Máquina e processo de preparação de bebidas com base em cartuchos de concentrado de bebida |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20071204 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20080304 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20080407 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20080415 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20110425 Year of fee payment: 3 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 4115502 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20110425 Year of fee payment: 3 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20110425 Year of fee payment: 3 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120425 Year of fee payment: 4 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120425 Year of fee payment: 4 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130425 Year of fee payment: 5 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130425 Year of fee payment: 5 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20140425 Year of fee payment: 6 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |