JP4062551B2 - ヒトケルベロスタンパク質 - Google Patents
ヒトケルベロスタンパク質 Download PDFInfo
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- JP4062551B2 JP4062551B2 JP54698998A JP54698998A JP4062551B2 JP 4062551 B2 JP4062551 B2 JP 4062551B2 JP 54698998 A JP54698998 A JP 54698998A JP 54698998 A JP54698998 A JP 54698998A JP 4062551 B2 JP4062551 B2 JP 4062551B2
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
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- Public Health (AREA)
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- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US4442797P | 1997-04-29 | 1997-04-29 | |
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| US4515797P | 1997-04-30 | 1997-04-30 | |
| US60/045,157 | 1997-04-30 | ||
| PCT/US1998/006324 WO1998049296A1 (en) | 1997-04-29 | 1998-03-31 | Human cerberus protein |
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| JP2001526535A JP2001526535A (ja) | 2001-12-18 |
| JP2001526535A5 JP2001526535A5 (https=) | 2005-11-24 |
| JP4062551B2 true JP4062551B2 (ja) | 2008-03-19 |
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| JP54698998A Expired - Lifetime JP4062551B2 (ja) | 1997-04-29 | 1998-03-31 | ヒトケルベロスタンパク質 |
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|---|---|
| US (2) | US6610510B1 (https=) |
| EP (1) | EP0975752A1 (https=) |
| JP (1) | JP4062551B2 (https=) |
| AU (1) | AU726385B2 (https=) |
| CA (1) | CA2288373C (https=) |
| IL (1) | IL132443A0 (https=) |
| NZ (1) | NZ500577A (https=) |
| WO (1) | WO1998049296A1 (https=) |
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| US6150328A (en) | 1986-07-01 | 2000-11-21 | Genetics Institute, Inc. | BMP products |
| US6291206B1 (en) | 1993-09-17 | 2001-09-18 | Genetics Institute, Inc. | BMP receptor proteins |
| AU689184B2 (en) | 1993-12-07 | 1998-03-26 | Genetics Institute, Llc | BMP-12, BMP-13 and tendon-inducing compositions thereof |
| WO1999061044A1 (en) * | 1998-05-28 | 1999-12-02 | The Board Of Trustees Of The University Of Arkansas | Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption |
| ATE481487T1 (de) * | 1998-11-27 | 2010-10-15 | Ucb Sa | Zusammensetzungen und verfahren zur erhöhung der knochenmineralisierung |
| US6727224B1 (en) | 1999-02-01 | 2004-04-27 | Genetics Institute, Llc. | Methods and compositions for healing and repair of articular cartilage |
| DK1223990T3 (da) | 1999-10-15 | 2004-11-29 | Inst Genetics Llc | Formuleringer af hyaluronsyre til tilförsel af osteogene proteiner |
| US7226587B2 (en) | 2001-06-01 | 2007-06-05 | Wyeth | Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins |
| JP2004532640A (ja) * | 2001-06-05 | 2004-10-28 | オークランド ユニサーヴィスィズ リミテッド | 肺機能および障害の評価のための方法および組成物 |
| TWI267378B (en) | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
| US20040176287A1 (en) * | 2001-06-08 | 2004-09-09 | Harrison Andrew James | Bmp binding proteins for use in bone or cartilage regeneration |
| GB2385052A (en) | 2002-02-05 | 2003-08-13 | Leuven K U Res & Dev | Treatment of spondyloarthropathies |
| US7193069B2 (en) * | 2002-03-22 | 2007-03-20 | Research Association For Biotechnology | Full-length cDNA |
| WO2004062621A2 (en) * | 2003-01-13 | 2004-07-29 | Georgia Tech Research Corporation | Anti-inflammatory agents and methods of their use |
| JP2008500373A (ja) * | 2004-05-27 | 2008-01-10 | アクセルロン ファーマ インコーポレーテッド | ケルベロス（Ｃｅｒｂｅｒｕｓ）／ココ（Ｃｏｃｏ）誘導体およびそれらの使用 |
| US9045553B2 (en) | 2004-05-27 | 2015-06-02 | Acceleron Pharma, Inc. | Cerberus/Coco derivatives and uses thereof |
| KR20080011289A (ko) * | 2005-05-10 | 2008-02-01 | 시너젠즈 바이오사이언스 리미티드 | 폐기능 및 폐질환을 평가하기 위한 성분 및 평가 방법 |
| WO2006123955A2 (en) * | 2005-05-19 | 2006-11-23 | Synergenz Bioscience Limited | Methods for the assesssment of risk of developing lung cancer using analysis of genetic polymorphisms |
| CA2608158A1 (en) * | 2005-05-19 | 2006-11-23 | Synergenz Bioscience Limited | Methods and compositions for assessment of pulmonary function and disorders |
| WO2006123943A1 (en) * | 2005-05-20 | 2006-11-23 | Synergenz Bioscience Limited | Methods of analysis of polymorphisms and uses thereof |
| CA2652549A1 (en) * | 2006-05-17 | 2007-12-13 | Stryker Corporation | Use of a soluble morphogenic protein complex for treating cartilage defects |
| CA2671983A1 (en) | 2006-12-08 | 2009-06-19 | Acceleron Pharma Inc. | Uses of cerberus, coco and derivatives thereof |
| CN105759056B (zh) * | 2016-04-06 | 2017-11-14 | 四川大学华西医院 | 一种肺癌筛查试剂盒 |
| US10961305B2 (en) | 2016-12-21 | 2021-03-30 | Mereo Biopharma 3 Limited | Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta |
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| US4952499A (en) * | 1988-02-11 | 1990-08-28 | Dana-Farber Cancer Institute | Genes and their encoded proteins which regulate gene expression of the interleukin-2 receptor and of human lymphotropic retroviruses |
| US6133232A (en) * | 1996-06-20 | 2000-10-17 | The Regents Of The University Of California | Endoderm, cardiac and neural inducing factors |
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1998
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- 1998-03-31 CA CA2288373A patent/CA2288373C/en not_active Expired - Lifetime
- 1998-03-31 IL IL13244398A patent/IL132443A0/xx unknown
- 1998-03-31 NZ NZ500577A patent/NZ500577A/xx not_active IP Right Cessation
- 1998-03-31 EP EP98914368A patent/EP0975752A1/en not_active Withdrawn
- 1998-03-31 WO PCT/US1998/006324 patent/WO1998049296A1/en not_active Ceased
- 1998-03-31 AU AU68736/98A patent/AU726385B2/en not_active Expired
- 1998-03-31 JP JP54698998A patent/JP4062551B2/ja not_active Expired - Lifetime
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2003
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| Publication number | Publication date |
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| US7241739B2 (en) | 2007-07-10 |
| EP0975752A1 (en) | 2000-02-02 |
| AU6873698A (en) | 1998-11-24 |
| NZ500577A (en) | 2001-02-23 |
| AU726385B2 (en) | 2000-11-02 |
| US6610510B1 (en) | 2003-08-26 |
| CA2288373A1 (en) | 1998-11-05 |
| WO1998049296A1 (en) | 1998-11-05 |
| IL132443A0 (en) | 2001-03-19 |
| JP2001526535A (ja) | 2001-12-18 |
| US20030199042A1 (en) | 2003-10-23 |
| CA2288373C (en) | 2010-06-01 |
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