JP4062551B2 - ヒトケルベロスタンパク質 - Google Patents

ヒトケルベロスタンパク質 Download PDF

Info

Publication number
JP4062551B2
JP4062551B2 JP54698998A JP54698998A JP4062551B2 JP 4062551 B2 JP4062551 B2 JP 4062551B2 JP 54698998 A JP54698998 A JP 54698998A JP 54698998 A JP54698998 A JP 54698998A JP 4062551 B2 JP4062551 B2 JP 4062551B2
Authority
JP
Japan
Prior art keywords
human
kerberos
protein
cell
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP54698998A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001526535A5 (https=
JP2001526535A (ja
Inventor
エム. バレンズエラ,デイビッド
エイ. ロジャス,エドゥアルド
エヌ. エコノミデス,アリス
イー. スタール,ニール
Original Assignee
リジェネロン ファーマシューティカルズ,インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26721541&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP4062551(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by リジェネロン ファーマシューティカルズ,インコーポレイテッド filed Critical リジェネロン ファーマシューティカルズ,インコーポレイテッド
Publication of JP2001526535A publication Critical patent/JP2001526535A/ja
Publication of JP2001526535A5 publication Critical patent/JP2001526535A5/ja
Application granted granted Critical
Publication of JP4062551B2 publication Critical patent/JP4062551B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP54698998A 1997-04-29 1998-03-31 ヒトケルベロスタンパク質 Expired - Lifetime JP4062551B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4442797P 1997-04-29 1997-04-29
US60/044,427 1997-04-29
US4515797P 1997-04-30 1997-04-30
US60/045,157 1997-04-30
PCT/US1998/006324 WO1998049296A1 (en) 1997-04-29 1998-03-31 Human cerberus protein

Publications (3)

Publication Number Publication Date
JP2001526535A JP2001526535A (ja) 2001-12-18
JP2001526535A5 JP2001526535A5 (https=) 2005-11-24
JP4062551B2 true JP4062551B2 (ja) 2008-03-19

Family

ID=26721541

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54698998A Expired - Lifetime JP4062551B2 (ja) 1997-04-29 1998-03-31 ヒトケルベロスタンパク質

Country Status (8)

Country Link
US (2) US6610510B1 (https=)
EP (1) EP0975752A1 (https=)
JP (1) JP4062551B2 (https=)
AU (1) AU726385B2 (https=)
CA (1) CA2288373C (https=)
IL (1) IL132443A0 (https=)
NZ (1) NZ500577A (https=)
WO (1) WO1998049296A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
DE69434651T2 (de) 1993-12-07 2007-03-08 Genetics Institute, Inc., Cambridge Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
WO1999061044A1 (en) * 1998-05-28 1999-12-02 The Board Of Trustees Of The University Of Arkansas Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption
DE69933044T3 (de) * 1998-11-27 2016-11-24 Ucb Pharma, S.A. Zusammensetzungen und verfahren zur erhöhung der knochenmineralisierung
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
PT1223990E (pt) 1999-10-15 2004-12-31 Fidia Advanced Biopolymers Srl Formulacoes de acido hialuronico para administracao de proteinas osteogenicas
EP1399023B1 (en) 2001-06-01 2008-04-30 Wyeth COMPOSITIONS FOR SYSTEMIC ADMINISTRATION OF SEQUENCES ENCODING BONE MORPHOGENETIC PROTEINS& x9;
EP1801240A1 (en) * 2001-06-05 2007-06-27 Auckland Uniservices Limited Methods and compositions for assessment of pulmonary function and disorders
WO2002100426A1 (en) * 2001-06-08 2002-12-19 Smith & Nephew Plc Bmp binding proteins for use in bone or cartilage regeneration
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
GB2385052A (en) * 2002-02-05 2003-08-13 Leuven K U Res & Dev Treatment of spondyloarthropathies
US7193069B2 (en) 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
WO2004062621A2 (en) * 2003-01-13 2004-07-29 Georgia Tech Research Corporation Anti-inflammatory agents and methods of their use
US9045553B2 (en) 2004-05-27 2015-06-02 Acceleron Pharma, Inc. Cerberus/Coco derivatives and uses thereof
US7833971B2 (en) 2006-12-08 2010-11-16 Acceleron Pharma Inc. Uses of cerberus, coco and derivatives thereof
AU2005247508A1 (en) * 2004-05-27 2005-12-08 Acceleron Pharma Inc. Cerberus/coco derivatives and uses thereof
US20060269946A1 (en) * 2005-05-10 2006-11-30 Young Robert P Methods and compositions for assessment of pulmonary function and disorders
JP2008545389A (ja) * 2005-05-19 2008-12-18 シナージェンズ バイオサイエンス リミティド 肺機能及び肺障害の評価のための方法及び組成物
KR20080011292A (ko) * 2005-05-19 2008-02-01 시너젠즈 바이오사이언스 리미티드 유전자 다형 분석을 사용하여 폐암 발생 위험을 평가하는방법
EP1888779A4 (en) * 2005-05-20 2009-06-10 Synergenz Bioscience Ltd METHOD FOR THE ANALYSIS OF POLYMORPHISMS AND USES THEREOF
EP2035030A2 (en) * 2006-05-17 2009-03-18 Stryker Corporation Use of a soluble morphogenic protein complex for treating cartilage defects
CN105759056B (zh) * 2016-04-06 2017-11-14 四川大学华西医院 一种肺癌筛查试剂盒
WO2018115879A1 (en) 2016-12-21 2018-06-28 Mereo Biopharma 3 Limited Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952499A (en) * 1988-02-11 1990-08-28 Dana-Farber Cancer Institute Genes and their encoded proteins which regulate gene expression of the interleukin-2 receptor and of human lymphotropic retroviruses
US6133232A (en) * 1996-06-20 2000-10-17 The Regents Of The University Of California Endoderm, cardiac and neural inducing factors

Also Published As

Publication number Publication date
NZ500577A (en) 2001-02-23
IL132443A0 (en) 2001-03-19
US6610510B1 (en) 2003-08-26
CA2288373A1 (en) 1998-11-05
JP2001526535A (ja) 2001-12-18
EP0975752A1 (en) 2000-02-02
WO1998049296A1 (en) 1998-11-05
US20030199042A1 (en) 2003-10-23
AU726385B2 (en) 2000-11-02
US7241739B2 (en) 2007-07-10
AU6873698A (en) 1998-11-24
CA2288373C (en) 2010-06-01

Similar Documents

Publication Publication Date Title
JP4062551B2 (ja) ヒトケルベロスタンパク質
EP1019502A2 (en) Human orphan receptor ntr-1
US6660499B1 (en) DCR5, a BMP-binding protein, and applications thereof
JP4357003B2 (ja) 形態形成タンパク質
JP2002508934A (ja) Tnfレセプターに対して相同性を有する、新規な核酸およびポリペプチド
JP2003514530A (ja) ポリペプチドおよびそれらをコードする核酸
JPH10201491A (ja) タンパク質ホスファターゼ1結合タンパク質r5
JP2003526369A (ja) 新規ポリヌクレオチドおよび同一物をコードする核酸
AU753400C (en) Orphan receptors
MXPA99009963A (en) Human cerberus protein
US6207413B1 (en) Nucleic acids encoding novel orphan cytokine receptors
WO1998037195A9 (en) Morphogenic proteins
JP2003511076A (ja) 大動脈カルボキシペプチダーゼ様タンパク質およびそれをコードする核酸
MXPA00011922A (en) Angiostatin-binding protein

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050330

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20050330

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20070710

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20071002

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20071204

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20071220

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110111

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110111

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120111

Year of fee payment: 4

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20130111

Year of fee payment: 5

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20130111

Year of fee payment: 5

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term