AU726385B2 - Human cerberus protein - Google Patents

Human cerberus protein Download PDF

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Publication number
AU726385B2
AU726385B2 AU68736/98A AU6873698A AU726385B2 AU 726385 B2 AU726385 B2 AU 726385B2 AU 68736/98 A AU68736/98 A AU 68736/98A AU 6873698 A AU6873698 A AU 6873698A AU 726385 B2 AU726385 B2 AU 726385B2
Authority
AU
Australia
Prior art keywords
human
cerberus
human cerberus
bmp
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU68736/98A
Other languages
English (en)
Other versions
AU6873698A (en
Inventor
Aris N. Economides
Eduardo A. Rojas
Neil E. Stahl
David M Valenzuela
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regeneron Pharmaceuticals Inc
Original Assignee
Regeneron Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26721541&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU726385(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharmaceuticals Inc filed Critical Regeneron Pharmaceuticals Inc
Publication of AU6873698A publication Critical patent/AU6873698A/en
Application granted granted Critical
Publication of AU726385B2 publication Critical patent/AU726385B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU68736/98A 1997-04-29 1998-03-31 Human cerberus protein Expired AU726385B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4442797P 1997-04-29 1997-04-29
US60/044427 1997-04-29
US4515797P 1997-04-30 1997-04-30
US60/045157 1997-04-30
PCT/US1998/006324 WO1998049296A1 (en) 1997-04-29 1998-03-31 Human cerberus protein

Publications (2)

Publication Number Publication Date
AU6873698A AU6873698A (en) 1998-11-24
AU726385B2 true AU726385B2 (en) 2000-11-02

Family

ID=26721541

Family Applications (1)

Application Number Title Priority Date Filing Date
AU68736/98A Expired AU726385B2 (en) 1997-04-29 1998-03-31 Human cerberus protein

Country Status (8)

Country Link
US (2) US6610510B1 (https=)
EP (1) EP0975752A1 (https=)
JP (1) JP4062551B2 (https=)
AU (1) AU726385B2 (https=)
CA (1) CA2288373C (https=)
IL (1) IL132443A0 (https=)
NZ (1) NZ500577A (https=)
WO (1) WO1998049296A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
AU689184B2 (en) 1993-12-07 1998-03-26 Genetics Institute, Llc BMP-12, BMP-13 and tendon-inducing compositions thereof
WO1999061044A1 (en) * 1998-05-28 1999-12-02 The Board Of Trustees Of The University Of Arkansas Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption
ATE481487T1 (de) * 1998-11-27 2010-10-15 Ucb Sa Zusammensetzungen und verfahren zur erhöhung der knochenmineralisierung
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
DK1223990T3 (da) 1999-10-15 2004-11-29 Inst Genetics Llc Formuleringer af hyaluronsyre til tilförsel af osteogene proteiner
US7226587B2 (en) 2001-06-01 2007-06-05 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
JP2004532640A (ja) * 2001-06-05 2004-10-28 オークランド ユニサーヴィスィズ リミテッド 肺機能および障害の評価のための方法および組成物
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
US20040176287A1 (en) * 2001-06-08 2004-09-09 Harrison Andrew James Bmp binding proteins for use in bone or cartilage regeneration
GB2385052A (en) 2002-02-05 2003-08-13 Leuven K U Res & Dev Treatment of spondyloarthropathies
US7193069B2 (en) * 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
WO2004062621A2 (en) * 2003-01-13 2004-07-29 Georgia Tech Research Corporation Anti-inflammatory agents and methods of their use
JP2008500373A (ja) * 2004-05-27 2008-01-10 アクセルロン ファーマ インコーポレーテッド ケルベロス(Cerberus)/ココ(Coco)誘導体およびそれらの使用
US9045553B2 (en) 2004-05-27 2015-06-02 Acceleron Pharma, Inc. Cerberus/Coco derivatives and uses thereof
KR20080011289A (ko) * 2005-05-10 2008-02-01 시너젠즈 바이오사이언스 리미티드 폐기능 및 폐질환을 평가하기 위한 성분 및 평가 방법
WO2006123955A2 (en) * 2005-05-19 2006-11-23 Synergenz Bioscience Limited Methods for the assesssment of risk of developing lung cancer using analysis of genetic polymorphisms
CA2608158A1 (en) * 2005-05-19 2006-11-23 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
WO2006123943A1 (en) * 2005-05-20 2006-11-23 Synergenz Bioscience Limited Methods of analysis of polymorphisms and uses thereof
CA2652549A1 (en) * 2006-05-17 2007-12-13 Stryker Corporation Use of a soluble morphogenic protein complex for treating cartilage defects
CA2671983A1 (en) 2006-12-08 2009-06-19 Acceleron Pharma Inc. Uses of cerberus, coco and derivatives thereof
CN105759056B (zh) * 2016-04-06 2017-11-14 四川大学华西医院 一种肺癌筛查试剂盒
US10961305B2 (en) 2016-12-21 2021-03-30 Mereo Biopharma 3 Limited Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952499A (en) * 1988-02-11 1990-08-28 Dana-Farber Cancer Institute Genes and their encoded proteins which regulate gene expression of the interleukin-2 receptor and of human lymphotropic retroviruses
US6133232A (en) * 1996-06-20 2000-10-17 The Regents Of The University Of California Endoderm, cardiac and neural inducing factors

Also Published As

Publication number Publication date
US7241739B2 (en) 2007-07-10
EP0975752A1 (en) 2000-02-02
AU6873698A (en) 1998-11-24
JP4062551B2 (ja) 2008-03-19
NZ500577A (en) 2001-02-23
US6610510B1 (en) 2003-08-26
CA2288373A1 (en) 1998-11-05
WO1998049296A1 (en) 1998-11-05
IL132443A0 (en) 2001-03-19
JP2001526535A (ja) 2001-12-18
US20030199042A1 (en) 2003-10-23
CA2288373C (en) 2010-06-01

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