JP3604699B2 - 多外傷後の多発性臓器不全の防止のための及び体外血液循環後の急性臓器損傷の防止のための抗−セレクチン抗体 - Google Patents

多外傷後の多発性臓器不全の防止のための及び体外血液循環後の急性臓器損傷の防止のための抗−セレクチン抗体 Download PDF

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Publication number
JP3604699B2
JP3604699B2 JP50943897A JP50943897A JP3604699B2 JP 3604699 B2 JP3604699 B2 JP 3604699B2 JP 50943897 A JP50943897 A JP 50943897A JP 50943897 A JP50943897 A JP 50943897A JP 3604699 B2 JP3604699 B2 JP 3604699B2
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JP
Japan
Prior art keywords
selectin
antibody
antibodies
dose
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP50943897A
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English (en)
Japanese (ja)
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JPH10510553A (ja
Inventor
ハゼルベク，アントン
シュマハー，ギンター
コ，マン，サン
マルティーン，ウルリヒ
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PDL Biopharma Inc
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Protein Design Labs Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
JP50943897A 1995-08-17 1996-08-14 多外傷後の多発性臓器不全の防止のための及び体外血液循環後の急性臓器損傷の防止のための抗−セレクチン抗体 Expired - Fee Related JP3604699B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP95112895 1995-08-17
EP95114696 1995-09-19
US57895395A 1995-12-27 1995-12-27
US08/578,953 1995-12-27
US95114696.8 1995-12-27
US95112895.8 1995-12-27
PCT/US1996/013152 WO1997006822A1 (en) 1995-08-17 1996-08-14 Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage

Publications (2)

Publication Number Publication Date
JPH10510553A JPH10510553A (ja) 1998-10-13
JP3604699B2 true JP3604699B2 (ja) 2004-12-22

Family

ID=27236574

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50943897A Expired - Fee Related JP3604699B2 (ja) 1995-08-17 1996-08-14 多外傷後の多発性臓器不全の防止のための及び体外血液循環後の急性臓器損傷の防止のための抗−セレクチン抗体

Country Status (11)

Country Link
EP (1) EP0868197B1 (https=)
JP (1) JP3604699B2 (https=)
AT (1) ATE265861T1 (https=)
AU (1) AU6773596A (https=)
CA (1) CA2229140A1 (https=)
CZ (1) CZ45498A3 (https=)
DE (1) DE69632407T2 (https=)
HU (1) HUP9901673A3 (https=)
PL (1) PL187090B1 (https=)
WO (1) WO1997006822A1 (https=)
ZA (1) ZA966954B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994511A (en) 1997-07-02 1999-11-30 Genentech, Inc. Anti-IgE antibodies and methods of improving polypeptides
US6172213B1 (en) 1997-07-02 2001-01-09 Genentech, Inc. Anti-IgE antibodies and method of improving polypeptides
GB9919713D0 (en) 1999-08-19 1999-10-20 Queen Mary & Westfield College New medical use of high density lipoprotein
NZ535425A (en) 2002-03-13 2008-05-30 Biogen Idec Inc Anti-alphavbeta6 antibodies
CN104072614B (zh) * 2005-07-08 2017-04-26 生物基因Ma公司 抗-αvβ6 抗体及其用途
CN101563105B (zh) 2006-07-10 2013-01-23 拜奥根Idec马萨诸塞公司 用于抑制smad4-缺陷癌症的组合物和方法
WO2014143739A2 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Anti-alpha v beta 6 antibodies and uses thereof
WO2014144466A1 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Anti-alpha v beta 6 antibodies and uses thereof
EP3883635A1 (en) 2018-11-19 2021-09-29 Progenity, Inc. Methods and devices for treating a disease with biotherapeutics
CN115666704B (zh) 2019-12-13 2025-09-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69232780T2 (de) * 1991-06-25 2003-01-30 Dana-Farber Cancer Institute, Boston Monoklonaler antikörper gegen lymphozytenassoziiertes zelloberflächenprotein
WO1993002698A1 (en) * 1991-07-29 1993-02-18 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies to leukocyte adhesion molecule-1
CZ140195A3 (en) * 1992-12-01 1996-06-12 Protein Desing Labs Humanized antibodies reacting with l-selectin
WO1995015181A1 (en) * 1993-11-30 1995-06-08 Protein Design Labs, Inc. Reperfusion therapy using antibodies to l-selectin

Also Published As

Publication number Publication date
EP0868197A4 (https=) 1998-11-18
PL325012A1 (en) 1998-07-06
JPH10510553A (ja) 1998-10-13
DE69632407T2 (de) 2005-06-02
DE69632407D1 (de) 2004-06-09
PL187090B1 (pl) 2004-05-31
HUP9901673A3 (en) 2001-06-28
HUP9901673A2 (hu) 1999-08-30
AU6773596A (en) 1997-03-12
EP0868197B1 (en) 2004-05-06
CA2229140A1 (en) 1997-02-27
EP0868197A1 (en) 1998-10-07
WO1997006822A1 (en) 1997-02-27
CZ45498A3 (cs) 1999-01-13
ZA966954B (en) 1998-02-16
ATE265861T1 (de) 2004-05-15

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