CA2229140A1 - Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage - Google Patents

Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage Download PDF

Info

Publication number
CA2229140A1
CA2229140A1 CA002229140A CA2229140A CA2229140A1 CA 2229140 A1 CA2229140 A1 CA 2229140A1 CA 002229140 A CA002229140 A CA 002229140A CA 2229140 A CA2229140 A CA 2229140A CA 2229140 A1 CA2229140 A1 CA 2229140A1
Authority
CA
Canada
Prior art keywords
selectin antibody
selectin
antibody
ser
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002229140A
Other languages
English (en)
French (fr)
Inventor
Anton Haselbeck
Gunther Schumacher
Man Sung Co
Ulrich Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scil Biomedicals GmbH
PDL Biopharma Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2229140A1 publication Critical patent/CA2229140A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002229140A 1995-08-17 1996-08-14 Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage Abandoned CA2229140A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP95112895 1995-08-17
EP95112895.8 1995-08-17
EP95114696.8 1995-09-19
EP95114696 1995-09-19
US57895395A 1995-12-27 1995-12-27
US08/578,953 1995-12-27

Publications (1)

Publication Number Publication Date
CA2229140A1 true CA2229140A1 (en) 1997-02-27

Family

ID=27236574

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002229140A Abandoned CA2229140A1 (en) 1995-08-17 1996-08-14 Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage

Country Status (11)

Country Link
EP (1) EP0868197B1 (https=)
JP (1) JP3604699B2 (https=)
AT (1) ATE265861T1 (https=)
AU (1) AU6773596A (https=)
CA (1) CA2229140A1 (https=)
CZ (1) CZ45498A3 (https=)
DE (1) DE69632407T2 (https=)
HU (1) HUP9901673A3 (https=)
PL (1) PL187090B1 (https=)
WO (1) WO1997006822A1 (https=)
ZA (1) ZA966954B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994511A (en) 1997-07-02 1999-11-30 Genentech, Inc. Anti-IgE antibodies and methods of improving polypeptides
US6172213B1 (en) 1997-07-02 2001-01-09 Genentech, Inc. Anti-IgE antibodies and method of improving polypeptides
GB9919713D0 (en) * 1999-08-19 1999-10-20 Queen Mary & Westfield College New medical use of high density lipoprotein
CN1646160A (zh) 2002-03-13 2005-07-27 拜奥根Idec马萨诸塞公司 抗αvβ6抗体
CN102875681A (zh) * 2005-07-08 2013-01-16 拜奥根Idec马萨诸塞公司 抗-αvβ6抗体及其用途
CN101563105B (zh) 2006-07-10 2013-01-23 拜奥根Idec马萨诸塞公司 用于抑制smad4-缺陷癌症的组合物和方法
WO2014143739A2 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Anti-alpha v beta 6 antibodies and uses thereof
US10035859B2 (en) 2013-03-15 2018-07-31 Biogen Ma Inc. Anti-alpha V beta 6 antibodies and uses thereof
US20220249814A1 (en) 2018-11-19 2022-08-11 Progenity, Inc. Methods and devices for treating a disease with biotherapeutics
CN121197633A (zh) 2019-12-13 2025-12-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2305192A (en) * 1991-06-25 1993-01-25 Dana-Farber Cancer Institute Monoclonal antibody to lymphocyte-associated cell surface protein
WO1993002698A1 (en) * 1991-07-29 1993-02-18 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies to leukocyte adhesion molecule-1
WO1994012215A1 (en) * 1992-12-01 1994-06-09 Protein Design Labs, Inc. Humanized antibodies reactive with l-selectin
AU2185195A (en) * 1993-11-30 1995-06-19 Protein Design Labs, Inc. Reperfusion therapy using antibodies to L-selectin

Also Published As

Publication number Publication date
PL325012A1 (en) 1998-07-06
JPH10510553A (ja) 1998-10-13
PL187090B1 (pl) 2004-05-31
EP0868197B1 (en) 2004-05-06
ATE265861T1 (de) 2004-05-15
HUP9901673A3 (en) 2001-06-28
WO1997006822A1 (en) 1997-02-27
DE69632407D1 (de) 2004-06-09
ZA966954B (en) 1998-02-16
DE69632407T2 (de) 2005-06-02
EP0868197A1 (en) 1998-10-07
HUP9901673A2 (hu) 1999-08-30
JP3604699B2 (ja) 2004-12-22
CZ45498A3 (cs) 1999-01-13
EP0868197A4 (https=) 1998-11-18
AU6773596A (en) 1997-03-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued