JP3578455B2 - 局所麻酔を回復させる方法およびそのための薬剤系 - Google Patents

局所麻酔を回復させる方法およびそのための薬剤系 Download PDF

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Publication number
JP3578455B2
JP3578455B2 JP50224593A JP50224593A JP3578455B2 JP 3578455 B2 JP3578455 B2 JP 3578455B2 JP 50224593 A JP50224593 A JP 50224593A JP 50224593 A JP50224593 A JP 50224593A JP 3578455 B2 JP3578455 B2 JP 3578455B2
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Prior art keywords
anesthesia
anesthetic
solution
injection
salt
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JP50224593A
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Japanese (ja)
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JPH06503099A (ja
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エム． アブラムソーン，グレン
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP50224593A 1991-07-01 1992-06-26 局所麻酔を回復させる方法およびそのための薬剤系 Expired - Lifetime JP3578455B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US72389991A 1991-07-01 1991-07-01
US723,899 1991-07-01
US812,409 1991-12-23
US07/812,409 US5192527A (en) 1991-07-01 1991-12-23 Method of reversing local anesthesia and reagent system therefor
PCT/US1992/005336 WO1993000932A1 (en) 1991-07-01 1992-06-26 Method of reversing local anesthesia and reagent system therefor

Publications (2)

Publication Number Publication Date
JPH06503099A JPH06503099A (ja) 1994-04-07
JP3578455B2 true JP3578455B2 (ja) 2004-10-20

Family

ID=27110888

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50224593A Expired - Lifetime JP3578455B2 (ja) 1991-07-01 1992-06-26 局所麻酔を回復させる方法およびそのための薬剤系

Country Status (11)

Country Link
US (1) US5192527A (cg-RX-API-DMAC7.html)
EP (1) EP0546160B1 (cg-RX-API-DMAC7.html)
JP (1) JP3578455B2 (cg-RX-API-DMAC7.html)
AT (1) ATE200627T1 (cg-RX-API-DMAC7.html)
AU (1) AU658347B2 (cg-RX-API-DMAC7.html)
CA (1) CA2090612C (cg-RX-API-DMAC7.html)
DE (1) DE69231792T2 (cg-RX-API-DMAC7.html)
DK (1) DK0546160T3 (cg-RX-API-DMAC7.html)
ES (1) ES2157904T3 (cg-RX-API-DMAC7.html)
GR (1) GR3036219T3 (cg-RX-API-DMAC7.html)
WO (1) WO1993000932A1 (cg-RX-API-DMAC7.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
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WO1994023748A1 (en) * 1993-04-08 1994-10-27 The University Of Queensland Administration of vaso-active agent and therapeutic agent
US6008256A (en) * 1995-08-28 1999-12-28 Showa Yakuhin Kako Co., Ltd. Composition for local anesthesia
AU5984801A (en) * 2000-05-12 2001-11-20 Novalar Pharmaceuticals Inc Local anesthetic methods and kits
US7229630B2 (en) * 2002-06-20 2007-06-12 Novalar Pharmaceuticals, Inc. Stabilized formulations of alpha adrenergic receptor antagonists and the uses thereof
EP2155214A1 (en) * 2007-05-22 2010-02-24 Glenn Abrahmsohn Method for pain control
US8828452B2 (en) * 2007-05-22 2014-09-09 Glenn Abrahmsohn Method for pain control
US8180446B2 (en) * 2007-12-05 2012-05-15 The Invention Science Fund I, Llc Method and system for cyclical neural modulation based on activity state
US8170660B2 (en) 2007-12-05 2012-05-01 The Invention Science Fund I, Llc System for thermal modulation of neural activity
US8165669B2 (en) * 2007-12-05 2012-04-24 The Invention Science Fund I, Llc System for magnetic modulation of neural conduction
US8165668B2 (en) * 2007-12-05 2012-04-24 The Invention Science Fund I, Llc Method for magnetic modulation of neural conduction
US8195287B2 (en) * 2007-12-05 2012-06-05 The Invention Science Fund I, Llc Method for electrical modulation of neural conduction
US8170658B2 (en) 2007-12-05 2012-05-01 The Invention Science Fund I, Llc System for electrical modulation of neural conduction
US8989858B2 (en) 2007-12-05 2015-03-24 The Invention Science Fund I, Llc Implant system for chemical modulation of neural activity
US8180447B2 (en) 2007-12-05 2012-05-15 The Invention Science Fund I, Llc Method for reversible chemical modulation of neural activity
DE102008005469A1 (de) * 2008-01-21 2009-07-23 Kettenbach Gmbh & Co. Kg Pastöses Einsetzmaterial zur Erweiterung des Zahnfleischsulcus und dessen Verwendung
US20090298946A1 (en) * 2008-06-02 2009-12-03 Cleavelin Cody R Local Anesthetic Deactivation
US20130310422A1 (en) 2010-09-01 2013-11-21 The General Hospital Corporation Reversal of general anesthesia by administration of methylphenidate, amphetamine, modafinil, amantadine, and/or caffeine
US8864017B2 (en) 2011-10-13 2014-10-21 Orbis Corporation Plastic corrugated container with improved fold lines and method and apparatus for making same
US9089560B2 (en) 2013-02-01 2015-07-28 Ocularis Pharma, Llc Methods and compositions for daily ophthalmic administration of phentolamine to improve visual performance
ES2762153T3 (es) 2013-02-01 2020-05-22 Ocuphire Pharma Inc Soluciones oftálmicas acuosas de fentolamina y usos médicos de las mismas
SG11201505907PA (en) * 2013-02-18 2015-08-28 Glenn Abrahmsohn Compositions and methods for pain relief without numbness
SG10201913330SA (en) 2013-09-11 2020-03-30 Glenn Abrahmsohn Hypertonic antimicrobial therapeutic compositions
EP3107551B1 (en) 2014-02-18 2020-10-28 Glenn Abrahmsohn Compositions comprising bicarbonate and calcium salts for pain relief without numbness
KR20210008328A (ko) 2018-03-07 2021-01-21 수부 랩스, 인크. 열 섬유의 자극을 통한 통증 완화 개선을 위한 시스템 및 방법
JP2022508715A (ja) 2018-10-15 2022-01-19 オキュフィア・ファーマ・インコーポレイテッド 緑内障および関連状態の処置のための方法および組成物
JP7670945B2 (ja) 2018-10-26 2025-05-01 オーパス・ジェネティクス・インコーポレイテッド 老眼、散瞳、および他の眼障害の治療のための方法および組成物
WO2020132310A1 (en) 2018-12-19 2020-06-25 The General Hospital Corporation Dextroamphetamine and lisdexamfetamine to reverse dexmedetomidine sedation
CN115368310B (zh) 2021-05-18 2025-06-27 奥库菲尔医药公司 合成甲磺酸酚妥拉明的方法
US12070454B1 (en) 2022-05-05 2024-08-27 Pfof Llc Anesthetic nerve block and method
IL316770A (en) 2022-05-05 2025-01-01 Pfof Llc Nerve block anesthesia and method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2746901A (en) * 1954-06-14 1956-05-22 American Home Prod Glycinamide salts
AU513753B2 (en) * 1974-07-08 1980-12-18 Johnson & Johnson Antimicrobial composition
HU172937B (hu) * 1975-12-18 1979-01-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija novykh proizvodnykh khondroitin-sernoj kisloty s mestno anestezirujuhhim ehffektom
US4476115A (en) * 1983-07-05 1984-10-09 Reed Raymond E Analgesic composition and method of treating subdermal pain
US4659714A (en) * 1984-03-27 1987-04-21 Dentsply, Ltd. Anesthetic methods for mammals
US4963345A (en) * 1988-07-18 1990-10-16 Forrest Kim K Injectable local anesthetic antidote
US4937078A (en) * 1988-08-26 1990-06-26 Mezei Associates Limited Liposomal local anesthetic and analgesic products

Also Published As

Publication number Publication date
CA2090612A1 (en) 1993-01-02
WO1993000932A1 (en) 1993-01-21
JPH06503099A (ja) 1994-04-07
DE69231792T2 (de) 2001-11-15
CA2090612C (en) 2007-05-29
GR3036219T3 (en) 2001-10-31
ATE200627T1 (de) 2001-05-15
AU658347B2 (en) 1995-04-06
EP0546160A4 (cg-RX-API-DMAC7.html) 1994-04-06
ES2157904T3 (es) 2001-09-01
AU2294892A (en) 1993-02-11
DE69231792D1 (de) 2001-05-23
US5192527A (en) 1993-03-09
EP0546160B1 (en) 2001-04-18
EP0546160A1 (en) 1993-06-16
DK0546160T3 (da) 2001-07-30

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