JP3329395B2 - テトラサイクリンのスクリーニング法 - Google Patents
テトラサイクリンのスクリーニング法Info
- Publication number
- JP3329395B2 JP3329395B2 JP35012692A JP35012692A JP3329395B2 JP 3329395 B2 JP3329395 B2 JP 3329395B2 JP 35012692 A JP35012692 A JP 35012692A JP 35012692 A JP35012692 A JP 35012692A JP 3329395 B2 JP3329395 B2 JP 3329395B2
- Authority
- JP
- Japan
- Prior art keywords
- tetracycline
- gene
- coli
- efflux pump
- teta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80363491A | 1991-12-06 | 1991-12-06 | |
| US803634 | 1991-12-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH05317093A JPH05317093A (ja) | 1993-12-03 |
| JP3329395B2 true JP3329395B2 (ja) | 2002-09-30 |
Family
ID=25187068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP35012692A Expired - Fee Related JP3329395B2 (ja) | 1991-12-06 | 1992-12-04 | テトラサイクリンのスクリーニング法 |
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| Country | Link |
|---|---|
| US (1) | US5789188A (enExample) |
| EP (1) | EP0547403A1 (enExample) |
| JP (1) | JP3329395B2 (enExample) |
| KR (1) | KR100245831B1 (enExample) |
| AU (1) | AU670551B2 (enExample) |
| CA (1) | CA2084404A1 (enExample) |
| NO (1) | NO304489B1 (enExample) |
| TW (1) | TW318189B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE40183E1 (en) | 1991-10-04 | 2008-03-25 | Wyeth Holdings Corporation | 7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
| US5494903A (en) | 1991-10-04 | 1996-02-27 | American Cyanamid Company | 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
| US5989832A (en) * | 1995-04-21 | 1999-11-23 | Microcide Pharmaceuticals, Inc. | Method for screening for non-tetracycline efflux pump inhibitors |
| US6068972A (en) | 1997-10-03 | 2000-05-30 | Trustees Of Tufts College | Methods and compositions for reducing bacterial tolerance to antibacterials, disinfectants and organic solvents |
| US6436694B1 (en) * | 1998-01-09 | 2002-08-20 | Cubist Pharmaceuticals, Inc. | Regulable gene expression in gram-positive bacteria |
| US6346391B1 (en) * | 1999-07-22 | 2002-02-12 | Trustees Of Tufts College | Methods of reducing microbial resistance to drugs |
| GB0123401D0 (en) * | 2001-09-28 | 2001-11-21 | Novartis Forschungsstiftung | Methods of inducing gene expression |
| EP1851245B1 (en) | 2005-01-26 | 2012-10-10 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
| GB0806803D0 (en) * | 2008-04-15 | 2008-05-14 | Scottish Biomedical Ltd | Reverse reporter assay |
| US9518283B1 (en) | 2012-02-27 | 2016-12-13 | Paradigm Diagnostics, Inc. | Selective enrichment media and uses thereof |
| CN110257471B (zh) * | 2019-06-06 | 2020-08-18 | 南京农业大学 | 利用生物传感器检测土壤中可提取态四环素类抗生素的试纸条及方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806529A (en) * | 1982-11-18 | 1989-02-21 | Trustees Of Tufts College, Tufts University | Tetracycline activity enhancement |
| US4911924A (en) * | 1987-04-17 | 1990-03-27 | University Of New Mexico | Induction of antibiotic hypersensitivity in tetracycline-resistance microorganisms |
| US5001230A (en) * | 1988-02-18 | 1991-03-19 | Schering Corporation | T cell activation markers |
| EP0468220A3 (en) * | 1990-07-26 | 1992-09-23 | American Cyanamid Company | Cloning of the biosynthetic pathway genes for chlortetracycline production from streptomyces aureofaciens & their expression in steptomyces lividans |
| ES2117630T3 (es) * | 1990-07-26 | 1998-08-16 | American Cyanamid Co | Cosmido bifuncional util para clonar adn actinomicetico. |
-
1992
- 1992-04-08 TW TW081102693A patent/TW318189B/zh active
- 1992-11-23 EP EP92119888A patent/EP0547403A1/en not_active Withdrawn
- 1992-12-04 CA CA002084404A patent/CA2084404A1/en not_active Abandoned
- 1992-12-04 AU AU29896/92A patent/AU670551B2/en not_active Ceased
- 1992-12-04 NO NO924705A patent/NO304489B1/no unknown
- 1992-12-04 JP JP35012692A patent/JP3329395B2/ja not_active Expired - Fee Related
- 1992-12-05 KR KR1019920023449A patent/KR100245831B1/ko not_active Expired - Fee Related
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1996
- 1996-05-13 US US08/644,931 patent/US5789188A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5789188A (en) | 1998-08-04 |
| JPH05317093A (ja) | 1993-12-03 |
| AU2989692A (en) | 1993-06-10 |
| EP0547403A1 (en) | 1993-06-23 |
| AU670551B2 (en) | 1996-07-25 |
| KR100245831B1 (ko) | 2000-04-01 |
| CA2084404A1 (en) | 1993-06-07 |
| NO924705L (no) | 1993-06-07 |
| NO924705D0 (no) | 1992-12-04 |
| TW318189B (enExample) | 1997-10-21 |
| NO304489B1 (no) | 1998-12-28 |
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