JP3245578B2 - ピロリジニルヒドロキサム酸化合物の製造方法 - Google Patents

ピロリジニルヒドロキサム酸化合物の製造方法

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Publication number
JP3245578B2
JP3245578B2 JP18308699A JP18308699A JP3245578B2 JP 3245578 B2 JP3245578 B2 JP 3245578B2 JP 18308699 A JP18308699 A JP 18308699A JP 18308699 A JP18308699 A JP 18308699A JP 3245578 B2 JP3245578 B2 JP 3245578B2
Authority
JP
Japan
Prior art keywords
compound
hydroxy
give
following formula
following structure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP18308699A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000072744A (ja
Inventor
ケイス・マイケル・デヴリーズ
ブライアン・クレメント・ヴァンダープラス
Original Assignee
ファイザー・プロダクツ・インク
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ファイザー・プロダクツ・インク filed Critical ファイザー・プロダクツ・インク
Publication of JP2000072744A publication Critical patent/JP2000072744A/ja
Application granted granted Critical
Publication of JP3245578B2 publication Critical patent/JP3245578B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP18308699A 1998-08-24 1999-06-29 ピロリジニルヒドロキサム酸化合物の製造方法 Expired - Fee Related JP3245578B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9763398P 1998-08-24 1998-08-24
US60/097633 1998-08-24

Publications (2)

Publication Number Publication Date
JP2000072744A JP2000072744A (ja) 2000-03-07
JP3245578B2 true JP3245578B2 (ja) 2002-01-15

Family

ID=22264376

Family Applications (1)

Application Number Title Priority Date Filing Date
JP18308699A Expired - Fee Related JP3245578B2 (ja) 1998-08-24 1999-06-29 ピロリジニルヒドロキサム酸化合物の製造方法

Country Status (18)

Country Link
US (1) US6031114A (enExample)
EP (1) EP0982297A3 (enExample)
JP (1) JP3245578B2 (enExample)
KR (1) KR100338916B1 (enExample)
CN (1) CN1245799A (enExample)
AR (1) AR016500A1 (enExample)
AU (1) AU4466599A (enExample)
BR (1) BR9902525A (enExample)
CA (1) CA2277242A1 (enExample)
HU (1) HUP9901944A3 (enExample)
ID (1) ID23462A (enExample)
IL (1) IL130429A0 (enExample)
IN (1) IN190844B (enExample)
PL (1) PL334144A1 (enExample)
RU (1) RU2163235C1 (enExample)
TR (1) TR199901546A2 (enExample)
YU (1) YU31499A (enExample)
ZA (1) ZA994285B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2445874A1 (en) 2001-04-30 2002-11-07 Fumitaka Ito Process for preparing hydroxypyrrolidinyl ethylamine compounds useful as kappa agonists
AU2003269399A1 (en) * 2002-11-01 2004-05-25 Pfizer Products Inc. Process for the preparation of pyrrolidinyl ethylamine compounds via a copper-mediated aryl amination
US7744750B2 (en) * 2005-11-17 2010-06-29 Exxonmobil Chemical Patents Inc. Process for reducing Bromine Index of hydrocarbon feedstocks
US8057664B2 (en) * 2005-11-17 2011-11-15 Exxonmobil Chemical Patents, Inc. Process for reducing bromine index of hydrocarbon feedstocks
US7517824B2 (en) * 2005-12-06 2009-04-14 Exxonmobil Chemical Company Process for steam stripping hydrocarbons from a bromine index reduction catalyst

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030339A1 (en) 1995-03-31 1996-10-03 Pfizer Inc. Pyrrolidinyl hydroxamic acid compounds and their production process

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8618188D0 (en) * 1986-07-25 1986-09-03 Ici Plc Diamine compounds
CA1336333C (en) * 1988-05-20 1995-07-18 Davide Della Bella Pyrrolidone-2 compounds and their use for central analgesic activity
DE4034785A1 (de) * 1990-11-02 1992-05-07 Merck Patent Gmbh 1-(2-arylethyl)-pyrrolidine
KR0132001B1 (ko) * 1994-05-21 1998-04-17 강박광 신규한 치환된 이미다졸 유도체
MX9701042A (es) * 1996-02-07 1998-05-31 Pfizer Compuestos del acido hidroxamico.
TNSN97092A1 (ar) * 1996-09-18 1999-12-31 Agouron Pharma مثبطات انزيم بروتيني فلزي وتركيبات صيدلانية تحتوي على تلك المثبتطات واستخدامها الصيدلاني وطرق ومركبات وسيطة مفيدة لتحضير التركيبات المذكورة.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030339A1 (en) 1995-03-31 1996-10-03 Pfizer Inc. Pyrrolidinyl hydroxamic acid compounds and their production process

Also Published As

Publication number Publication date
HUP9901944A3 (en) 2001-10-29
CA2277242A1 (en) 2000-02-24
TR199901546A3 (tr) 2000-04-21
TR199901546A2 (xx) 2000-04-21
US6031114A (en) 2000-02-29
AU4466599A (en) 2000-03-09
IN190844B (enExample) 2003-08-23
IL130429A0 (en) 2000-06-01
AR016500A1 (es) 2001-07-04
EP0982297A2 (en) 2000-03-01
ZA994285B (en) 2001-01-02
BR9902525A (pt) 2000-05-02
JP2000072744A (ja) 2000-03-07
KR100338916B1 (ko) 2002-05-30
CN1245799A (zh) 2000-03-01
ID23462A (id) 2000-04-27
KR20000016898A (ko) 2000-03-25
PL334144A1 (en) 2000-02-28
HUP9901944A2 (hu) 2000-06-28
RU2163235C1 (ru) 2001-02-20
EP0982297A3 (en) 2001-08-01
YU31499A (sh) 2002-11-15
HU9901944D0 (en) 1999-08-30

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