JP3236649U - Freeze transfer device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To maintain a low temperature environment for a long period of time, effectively monitor the environment of a freeze storage tube during a transfer process, effectively detect a temperature in a tank, and intelligently operate the transfer of a biological sample. Provide a freezing transfer device that can ensure safety. SOLUTION: The tank body 1, the adsorbent 2, the filling member 3 and the tank lid are included, the adsorbent is installed in the tank body, and the filling member is installed above the adsorbent and filled. The cryopreservation box, which includes the attachment part 7 and the filling storage part, can be placed in the filling part, and a plurality of cooling holes 5 are installed so as to penetrate between the filling part and the filling storage part. The tank lid is covered on the tank body, and the inside of the tank wall of the tank body is a vacuum cavity layer. A positioning support ring road is installed in the tank body to position and support the mounting member in the tank body, and a positioning ball leading plug is extended toward the tank body on the positioning support ring road. [Selection diagram] Fig. 2

Description

The present invention relates to the field of storage, retrieval and transfer equipment for biological samples. More specifically, it relates to a freeze transfer device.

The cryobiological sample storage is currently an important basic facility for research work in the fields of medicine and biology, and the low-temperature storage of liquid nitrogen activates biological tissues such as blood, stem cells, and immune cells for a long period of time. Can be transformed into. After obtaining the biological sample, store the biological sample one by one in each cryostorage tube, then place the cryostorage tube in the cryostorage box and transfer the biological sample into the cryostorage tank. And keep it. In the prior art, the process of transferring a freezing storage box to a freezing storage tank uses a normal tank, fills it with liquid nitrogen, temporarily cools the tank to create a temporary frozen environment, and then , The frozen storage box is put in it and then transferred. Such a transfer method poses a great risk to the biological sample of the cryostorage tube in the cryostorage box and does not always maintain a frozen environment. Taking China Patent Application No. 2016112378301 as an example, it is disclosed that a flexible liquid nitrogen adsorption block for adsorbing liquid nitrogen is installed in a liquid nitrogen tank in the prior art, but a flexible liquid nitrogen adsorption block and cryopreservation are disclosed. Due to the large distance from the sample rack in which the tube is placed, there is a large limitation on the cooling of the cryostorage tube, and during the transfer process, the cryostorage tube cannot detect the ambient temperature in the tank and the temperature. The change in has an undetectable effect on the frozen environment in the tank.

An object of the present invention is to provide a freeze transfer device. This maintains a cold environment for a long period of time, effectively monitors the environment of the cryostorage tube during the transfer process, effectively detects and intelligently manipulates the temperature inside the tank, and transfers biological samples. Safety can be ensured.

The present invention solves a technical problem by adopting the following technical solutions. The adsorbent includes a tank body, an adsorbent, a filling member and a tank lid, the adsorbent is installed in the tank, the filling member is installed above the adsorbent, and the mounting member is placed on the stacking member. A plurality of cooling holes are provided, the freeze storage box can be stored in the filling member, the tank lid is covered on the tank body, and the inside of the tank wall of the tank body is a vacuum cavity layer. A freeze transfer device is provided.

Preferably, the laying member includes a laying portion and a laying accommodating portion, the adsorbent can be located in the laying accommodating portion, and the freeze storage box is laid in the laying portion. A plurality of cooling holes are penetrated and installed between the filling portion and the filling accommodating portion.

Preferably, a base receiving groove is recessed downward on the end surface of the adsorbent, and the veneer member includes a veneer, a veneer ring, and a veneer support ring, and the lower end of the veneer ring. Is fixed to the outer circumference of the circumference of the veneer, a plurality of honeycomb-shaped cooling holes are opened on the veneer, and a plurality of circumferential arrays are formed on the veneer ring. A vertical cooling passage is opened, a veneer ring extends around the circumference of the upper end of the veneer ring, and a veneer support ring faces downward at the other end of the veneer ring. Installed vertically, the veneer support ring, the lower end surface of the veneer plate, and the veneer plate ring surround and serve as a veneer accommodating portion, and the veneer plate ring and the upper end surface of the veneer plate are veneered. A veneer groove is formed as a portion.

If necessary, the laying member includes a laying A plate and a laying A support ring, and the circumference of the laying A plate is fixed perpendicularly to the upper end of the laying A support ring. A plurality of cooling holes are opened in the stake A plate, the upper end surface of the stake A plate forms a stake portion, and the lower end surface of the stake A plate and the stake A support ring are formed. It surrounds and becomes a storage area.

Preferably, a positioning support ring road is installed in the tank body, a positioning ball leading plug is extended toward the tank body on the positioning support ring road, and the positioning support ring road is a mounting member. Is positioned and supported inside the tank.

Preferably, the control device further includes a control device capable of detecting, recording and displaying the temperature inside the tank.

Preferably, the tank body base is further included, and the tank body is installed on the tank body base.

Preferably, the battery is further included, the battery is installed at the bottom of the tank body base, and the battery is electrically connected to the control device.
The control device includes a control circuit board, a display, a temperature sensor and an alarm member.
The temperature sensor senses the temperature inside the tank, the temperature sensor is electrically connected to the control circuit board, the control circuit board is electrically connected to the display, and the display is the display. Installed outside the tank body, the alarm member is electrically connected to the control circuit board.

Preferably, the tank lid includes a tank lid body and a sealed foam lid, the tank lid body is laid over the tank body, and the tank lid body has a sealed foam lid extending toward the inside of the tank. The sealed foam lid is provided and seals the tank body.

Preferably, the reinforced outer annular plate, sleeve ring plate and handle are further included.
The reinforced outer annular plate is ring-sleeved and fixed to the outer circumference of the tank body, the sleeve ring plate is ring-sleeved and fixed to the outer circumference of the reinforced outer annular plate, and the handle is the sleeve ring. It is installed on the board.

The present invention has the following beneficial effects. An adsorbent is installed inside the tank, and at the same time, a filling member that covers the adsorbent is installed, and a plurality of cooling holes are installed in the mounting member, and freeze storage is performed on the mounting member. A box can be placed, the adsorbent maintains the freezing action on the filling member with the liquid nitrogen adsorbed by the cooling holes, and the low temperature environment is maintained for a long period of time, and the filling member freezes and stores the liquid nitrogen of the adsorbent. It acts directly and effectively on the box, increasing the safety of transporting biological samples.

It is a structural schematic diagram of a freeze transfer device. It is an exploded view of a freeze transfer device. It is a structural schematic diagram which installs a positioning support ring road on a tank body. It is an enlarged view of the part A of FIG. It is sectional drawing in the case of installing the filling member including the filling A plate in the freeze transfer device. It is sectional drawing in the case of installing the filling member including the filling plate in the freeze transfer device. It is a schematic structural drawing from the upper surface direction of the mounting member of one embodiment. It is a schematic structural view from the lower surface direction of the mounting member of FIG. It is sectional drawing of the mounting member of FIG. It is a structural schematic diagram of the mounting member of another embodiment.

Hereinafter, the technical solution of the present invention will be further described together with examples and drawings.

Example 1
This embodiment includes a tank body 1, an adsorbent 2, a stacking member 3, and a tank lid 4. The adsorbent 2 is installed in the tank body 1, and the stacking member 3 is the adsorbent 2. A plurality of cooling holes 5 are installed on the filling member 3, the freeze storage box 6 can be stored in the filling member 3, and the tank lid 4 is placed on the tank body 1. The inside of the tank wall of the tank body 1 which is covered provides a freezing transfer device which is a vacuum cavity layer 22.

When it is necessary to transfer the cryostorage tube regardless of whether it is a single or a large number of cryostorage tubes, first, a sufficient amount of liquid nitrogen is filled in the tank body 1 and the cryostorage tube is filled. The freeze storage box 6 is placed on the filling member 3, and the tank lid 4 is closed for transfer. Since the adsorbent 2 is composed of an adsorbent, it can adsorb liquid nitrogen. After the adsorbent 2 has sufficiently adsorbed liquid nitrogen, a plurality of cooling holes 5 which are through holes are installed on the filling member 3, so that the liquid nitrogen adsorbed on the adsorbent 2 is collected by the cooling holes 5. The cryopreservation box 6 radiated above the filling member 3 and arranged on the filling member 3 is always in a frozen environment. In addition, since the liquid nitrogen and the cryopreservation box 6 are effectively in direct contact with each other by installing the filling member 3, the environmental stability of the cryopreservation tube is guaranteed and the safety of the transfer of the biological sample is enhanced. .. The inside of the tank wall of the tank body is a vacuum cavity layer, and the vacuum cavity layer enhances the heat insulating property between the inside of the tank body and the outside of the tank body, and improves the cold and heat retaining effect.

In a preferred further embodiment of the present embodiment, the filling member 3 includes a filling portion 7 and a filling accommodating portion 8, and the adsorbent 2 can be located in the filling accommodating portion 8. The freeze storage box 6 can be placed in the filling portion 7, and a plurality of cooling holes 5 are installed so as to penetrate between the filling portion 7 and the filling accommodating portion 8. Such an installation further brings the cryostorage tube into contact with liquid nitrogen more directly and effectively, making the environment more stable.

In a preferred embodiment of the veneer 3 and the adsorbent 2 of this embodiment, a base receiving groove 9 is recessed downward on the end surface of the adsorbent 2, and the veneer 3 is a veneer 10. The veneer ring 11 and the veneer support ring 12 are included, and the lower end of the veneer ring 11 is fixed to the outer circumference of the circumference of the veneer 10, and a plurality of veneer rings 10 are mounted on the veneer 10. A honeycomb-shaped cooling hole 5 is opened, and vertical cooling passages 13 of a plurality of circumferential arrays are opened on the veneer ring 11, and the circumference of the upper end of the veneer ring 11 is surrounded. A veneer ring 14 is extended to the veneer, and a veneer support ring 12 is vertically installed downward at the other end of the veneer ring 14, and the lower end surfaces of the veneer support ring 12 and the veneer plate 10 are installed. And the veneer ring 11 surrounds and becomes a veneer accommodating portion 8, and the upper end surfaces of the veneer ring 11 and the veneer 10 form a veneer groove 15 as a veneer portion.

The veneer groove 15 formed by the veneer ring 11 and the veneer 10 just falls into the base receiving groove 9 of the adsorbent 2, and the adsorbent 2 is arranged exactly in the veneer accommodating portion 8. Will be done. A plurality of vertical cooling passages 13 of the circumferential array are opened on the veneer ring 11, and a plurality of honeycomb-shaped cooling holes 5 are opened on the veneer 10. As a result, the freeze storage box 6 arranged in the veneer groove 15 can receive not only from the lower veneer 10 but also from the cooling passage 13 of the veneer ring 11, and all the cooling liquid nitrogen can be received. It can be received in the circumferential direction of, which greatly improves the effectiveness and stability of the cold environment.

In this embodiment, another embodiment of the filling member 3 is further disclosed. The laying member 3 includes a laying A plate 16 and a laying A support ring 17, and the circumference of the laying A plate 16 is vertically fixed to the upper end of the laying A support ring 17. A plurality of cooling holes 5 are opened in the laying A plate 16, and the upper end surface of the laying A plate 16 forms a laying portion 7, and is laid with the lower end surface of the laying A plate 16. The A support ring 17 surrounds and becomes a filling accommodating portion 8. With such an installation, the freeze storage tube can be brought into direct and effective contact with the adsorbent 2 and more freeze storage tubes can be loaded.

In a preferred further embodiment of the present embodiment, a positioning support ring road 18 is installed in the tank body 1, and a positioning ball leading plug 19 extends toward the tank body on the positioning support ring road 18. The positioning support annular strip 18 positions and supports the filling member 3 in the tank body 1. When installing the mounting member 3, the position of the mounting member 3 can be determined by the positioning support annular strip 18, and the mounting member 3 is provided with an upward bearing force in the radial direction by using the positioning ball leading plug 19. To increase the stability of the filling member 3.

In a preferred further embodiment of this embodiment, the control device 20 further includes a control device 20 capable of detecting, recording and displaying the temperature inside the tank. By installing the control device 20, the transfer time and the temperature inside the tank body 1 can be observed through the control device 20 during the transfer process, and once the temperature is too high, the content of liquid nitrogen in the tank body is too low. The controller issues an alarm and informs the transfer personnel to transfer to the nearest biological sample storage as soon as possible. Prolonged storage of biological samples at room temperature causes damage. After transport is complete, temperature recordings can be extracted from the controller via external data lines for analysis and research by the experimenter.

In a preferred further embodiment of the present embodiment, the tank body base 21 is further included, and the tank body 1 is installed on the tank body base 21.

In a preferred further embodiment of the present embodiment, the battery 23 is further included, the battery 23 is installed at the bottom of the tank body base 21, and the battery 23 is electrically connected to the control device 20 to control the control. The device 20 includes a control circuit board, a display 24, a temperature sensor 25, and an alarm member, the temperature sensor 25 senses the temperature inside the tank body 1, and the temperature sensor 25 electrically connects to the control circuit board. The control circuit board is electrically connected to the display 24, the display 24 is installed outside the tank body 1, and the alarm member is electrically connected to the control circuit board. To.

In a preferred further embodiment of the present embodiment, the tank lid 4 includes a tank lid body 26 and a sealed foam lid 27, the tank lid body 26 is overlaid on the tank body 1, and the tank lid body 26 is covered. A sealed foam lid 27 is extended toward the inside of the tank, and the sealed foam lid 27 seals the tank body.

Further including a reinforced outer annular plate 28, a sleeve ring plate 29 and a handle 30, the reinforced outer annular plate 28 is ring-sleeved and fixed to the outer circumference of the tank body 1, and the sleeve ring plate 29 is a ring-sleeve type. The handle 30 is fixed to the outer circumference of the reinforced outer annular plate 28, and the handle 30 is installed on the sleeve ring plate 29. The reinforced outer annular plate 28 and the sleeve ring plate 29 can be used to enhance the stability of the structure, and the handle 30 can facilitate the transfer of the handbag.
The ordering of the above embodiments is for ease of explanation only and does not represent the strengths or weaknesses of the embodiments.

Finally, it is said that the above embodiments are used only to illustrate the technical solution of the present invention and are not limited thereto. Although the present invention has been described in detail with reference to the above embodiments, one of ordinary skill in the art needs to understand the following: It is still possible to modify the technical solutions described in the aforementioned examples, or to involve equivalent substitutions for some technical properties. These changes or replacements do not cause the essence of the corresponding technical solution to deviate from the spirit and scope of the technical solution of the embodiments of the present invention.

1-tank body; 2-adsorbent; 3-filling member; 4-tank lid; 5-cooling hole; 6-freeze storage box; 7-filling section; 8-filling storage section; 9-base receiving groove 10-Veneer plate; 11-Veneer ring; 12-Veneer support ring; 13-Cooling passage; 14-Connection plate ring; 15-Veneer groove; 16-Veneer A plate; 17-Veneer A Support ring; 18-Positioning support ring; 19-Positioning ball lead plug; 20-Control device; 21-Tank body base; 22-Vacuum cavity layer; 23-Battery; 24-Display; 25-Temperature sensor; 26-Tank Closure body; 27-sealed foam lid; 28-reinforced outer annular plate; 29-sleeve ring plate; 30-handle.

Claims (10)

Includes tank body, adsorbent, filling member and tank lid,
The adsorbent is installed in the tank, the mounting member is installed above the adsorbent, a plurality of cooling holes are installed on the stacking member, and freeze storage is performed in the stacking member. Can store boxes,
A freeze transfer device, wherein the tank lid is covered on the tank body, and the inside of the tank wall of the tank body is a vacuum cavity layer. The filling member includes a filling portion and a filling storage portion, the adsorbent can be located in the filling storage portion, and the freeze storage box can be loaded in the filling portion. The freeze transfer device according to claim 1, wherein a plurality of cooling holes are penetrated and installed between the filling portion and the filling accommodating portion. A base receiving groove is recessed downward on the end face of the adsorbent.
The veneer member includes a veneer plate, a veneer ring and a veneer support ring.
The lower end of the veneer ring is fixed to the outer circumference of the veneer, and a plurality of honeycomb-shaped cooling holes are opened on the veneer, and the veneer ring has a plurality of honeycomb-shaped cooling holes. , Vertical cooling passages of multiple circumferential arrays are opened,
A connecting plate ring is extended around the circumference of the upper end of the veneer ring, and a veneer support ring is vertically installed downward at the other end of the connecting plate ring.
The filling support ring, the lower end surface of the filling plate, and the filling plate ring surround it to form a filling storage portion, and the filling plate ring and the upper end surface of the filling plate form a filling groove as a filling portion. The freeze transfer device according to claim 2, wherein the freeze transfer device is formed. The laying member includes a laying A plate and a laying A support ring, and the circumference of the laying A plate is fixed vertically to the upper end of the laying A support ring, and the laying A is fixed. The board has multiple cooling holes,
2. The freeze transfer device according to. A positioning support ring road is installed in the tank body, a positioning ball leading plug is extended toward the tank body on the positioning support ring road, and the positioning support ring road has a mounting member in the tank. The freeze transfer device according to claim 2, wherein the freeze transfer device is positioned and supported in the body. The freeze transfer device according to any one of claims 1 to 5, further comprising a control device, wherein the control device can detect, record, and display a temperature inside a tank. The freeze transfer device according to claim 6, further comprising a tank body base, wherein the tank body is installed on the tank body base. Further including a battery, the battery is installed at the bottom of the tank body base, and the battery is electrically connected to the control device.
The control device includes a control circuit board, a display, a temperature sensor and an alarm member.
The temperature sensor senses the temperature inside the tank, the temperature sensor is electrically connected to the control circuit board, the control circuit board is electrically connected to the display, and the display is the display. The freeze transfer device according to claim 6, wherein the alarm member is installed outside the tank body and the alarm member is electrically connected to the control circuit board. The tank lid includes a tank lid main body and a sealed foam lid, the tank lid main body is covered on the tank body, and the sealed foam lid is extended toward the tank body on the tank lid main body. The freeze transfer device according to claim 1, wherein the sealed foam lid seals the tank body. Including reinforced outer annular plate, sleeve ring plate and handle,
The reinforced outer annular plate is ring-sleeved and fixed to the outer circumference of the tank body, the sleeve ring plate is ring-sleeved and fixed to the outer circumference of the reinforced outer annular plate, and the handle is the sleeve ring. The freeze transfer device according to claim 1, wherein the freeze transfer device is installed on a plate.

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