CN209898092U - Novel freezing storage box - Google Patents

Abstract

The utility model provides a novel cryopreserved box relates to biomedical equipment field, and this cryopreserved box is connected with rotatable lid including the box body that can the holding by cryopreserved sample on the box body, is equipped with the sample cell on the lid in order to supply the box body sample of taking. The utility model discloses a freezing box has abandoned traditional needs and has opened the freezing box design of sample with whole lid, and will freeze the lid design of depositing the box for the rotation type, sets up the thief hole simultaneously on the lid, so, the rotatory box cover of accessible makes the thief hole aim at the required sample of taking, can prevent effectively that other need not the sample of taking directly expose among the room temperature, reduces the influence to the sample that need not to take.

Description

Novel freezing storage box

Technical Field

The utility model relates to a biomedical equipment field especially indicates a novel cryopreserved box.

Background

At present, cryopreservation is a common way for storing cells or other samples in the field of biological medicine, and the process generally comprises the steps of mixing the cells or the samples with a cryopreservation solution, slowly cooling, transferring the cryopreservation tube to a cryopreservation box after the temperature is reduced to-80 ℃, and putting the cryopreservation tube into liquid nitrogen for long-term storage. When the cells or samples need to be reused, a process of activating and recovering frozen cells is needed, and the principle is quick thawing, so that the ice crystals are prevented from being recrystallized and the cells are prevented from being damaged. Therefore, the cryopreservation box is taken out of the liquid nitrogen tank, the cryopreservation tube is taken out of the cryopreservation box, and the cryopreservation tube is moved to the operation table, and the steps are dozens of seconds in short but are very important for the vitality and survival rate of the cells after recovery.

At present domestic commonly used cryopreserved box generally comprises split type lid and box body, and the lid superscript has corresponding identification code, and there are several defects in this kind of structure: firstly, an experimenter often only needs to take a few freezing tubes, but the box cover needs to be opened in each taking process, so that all the freezing tubes in the freezing box can be directly exposed in a room temperature environment to damage cells or samples; secondly, the freezing storage box cover is easy to deform at low temperature, so that the box belt is not easy to open, and the identification code corresponding to the freezing storage tube is written on the box cover and faces the box cover to find the position of the freezing storage tube, so that the time is long and the freezing storage box cover is easy to mix; finally, if the freezing storage box with the split design is knocked over or slipped off in the liquid nitrogen tank, the freezing storage tube inside is easy to spill at the bottom of the liquid nitrogen tank, and is extremely difficult to retrieve.

In view of the foregoing, there is a great need for development and improvement of conventional cryopreservation boxes.

SUMMERY OF THE UTILITY MODEL

The utility model discloses the technical problem that will solve is: how to take samples from the cryopreservation box does not influence other samples as much as possible.

In order to solve the technical problem, the utility model discloses a novel freeze and deposit box should freeze and deposit the box body that the box includes but the holding is frozen and deposits the sample, is connected with rotatable lid on the box body, is equipped with the sample connection on the lid in order to supply the box body sample of taking.

In a further scheme, a sealing type threaded connection is arranged between the box body and the box cover so as to seal and rotate the box body and the box cover.

In a further scheme, a buckle is further arranged at the joint of the box body and the box cover to prevent the box cover from excessively rotating to be separated from the box body.

In a further scheme, sample grooves for accommodating samples are distributed in the box body, and the opening positions of the sample grooves are matched with the sampling holes, so that when the box cover is rotated, each sample groove opening is provided with a sampling hole corresponding to the sampling hole, and the samples are taken out.

In a further scheme, the box body comprises a blank area, and the blank area is not provided with a sample groove, so that the box cover can be rotated to enable the sampling hole to be aligned to the blank area when sampling is not needed.

In a further scheme, the depth of the sample groove is smaller than the height of a cryopreservation tube which can be placed in the sample groove, and the height from the bottom of the sample groove to the box cover is larger than the height of the cryopreservation tube.

In a further scheme, an identifier is arranged near each sample groove so as to uniquely correspond to one sample groove through the identifier, and the aperture size of each sampling hole at least meets the requirement that the identifier can be exposed from the sampling hole when the sampling hole rotates to correspond to the sample groove.

In a further aspect, all of the sample wells except the blank region are distributed in an annular array within the cartridge body.

In a further scheme, the sample grooves are arranged in three circles from the center to the outside, three sampling holes are arranged on the box cover corresponding to the sample grooves, and the three sampling holes are sequentially arranged in a row from the center to the outside.

In a further scheme, the box body is filled with a polyurethane heat-insulating material, and the shell of the box body and the box cover are made of high-density crosslinked polyethylene materials.

The utility model discloses a freezing box has abandoned driven needs and has opened the freezing box design of sample with whole lid, and will freeze the lid design of depositing the box for the rotation type, sets up the thief hole simultaneously on the lid, so, the rotatory box cover of accessible makes the thief hole aim at the required sample of taking, can prevent effectively that other need not the sample of taking directly expose among the room temperature, reduces the influence to the sample that need not to take.

Drawings

The following detailed description of the specific structure of the present invention with reference to the accompanying drawings

FIG. 1 is a schematic view of the overall structure of a novel cryopreservation box;

FIG. 2 is a cross-sectional view of a novel cryopreservation box;

fig. 3 is a top view of the body of a novel cryopreservation box.

In the figure, 1-box cover, 2-sampling hole, 3-box body and 4-sample groove.

Detailed Description

In order to explain technical contents, structural features, and objects and effects of the present invention in detail, the following description is given in conjunction with the embodiments and the accompanying drawings.

With reference to fig. 1-3, in an embodiment, a novel cryopreservation box is disclosed, which includes a box body 3 capable of accommodating a sample to be cryopreserved, a rotatable box cover 1 is connected to the box body 3, and a sampling hole 2 is formed in the box cover 1 for taking the sample in the box body. So design, when needing the sample, only need rotate lid 1 and make the sample in 2 alignment box bodies 3 of thief hole on the lid 1 to alright take out the sample from 2 departments of thief hole. Therefore, in the sampling process, the influence on the sample which does not need to be taken can be reduced to the maximum extent, and the risk of exposure to the room temperature is reduced. For the convenience of rotation, the box body 3 and the box cover 1 can be preferably arranged in a cylindrical shape, for example, the box body 3 can be arranged in a similar cylindrical cavity, and various samples are accommodated in the box body 3. Meanwhile, the rotation of the box cover 1 can be along the rotation of the self axis to adjust the position corresponding to the sampling hole 2 on the box cover 1.

On the basis of the above scheme, for the mutual rotation connection relationship between the box cover 1 and the box body 3, specifically, a sealing type threaded connection (not shown in a threaded diagram) is adopted between the box body 3 and the box cover 1 for sealing and rotating the two. Namely, the sealing of the freezing storage box can be realized, and the mutual rotation between the box cover 1 and the box body 3 can be ensured.

In addition, the existing freezing storage box with split design is further considered, if the freezing storage box is overturned or slipped in a liquid nitrogen tank, the freezing storage tube inside is easy to spill at the bottom of the liquid nitrogen tank, and is extremely difficult to retrieve. It is preferable that a snap (not shown) is further provided at the connection between the box body 3 and the box cover 1 to prevent the box cover 1 from being excessively rotated to be separated from the box body 1. Namely, because the existence of buckle for although can be to a certain extent free rotation between box body 3 and lid 1, nevertheless unable separation all the time realizes undetachable between them, prevents that the sample from spilling.

Referring to fig. 2 and 3, in a specific embodiment, sample slots 4 for accommodating samples are distributed in the box body 3, and the opening positions of the sample slots 4 are matched with the sampling holes 2, so that when the box cover 1 is rotated, the sampling holes 2 correspond to the openings of the sample slots 4, and samples are taken out.

Referring to fig. 3, in an embodiment, the box body 3 includes a blank area, and the blank area is not provided with a sample slot, so that the sampling hole can be aligned to the blank area by rotating the box cover 1 when sampling is not needed. Thus, when sampling is not needed, the direct contact of the sample in the sample groove 4 and the room temperature or the direct exposure from the sampling hole 2 can be reduced. That is, when sampling is required, the sampling holes 2 on the box cover 1 can be aligned with the corresponding sample grooves 4 by rotating the box cover 1; when sampling is not needed, the sampling holes on the box cover 1 can stay in the blank area by rotating the box cover 1 and not aligning any sample groove.

In one embodiment, the depth of the sample tank 4 is less than the height of the vial that can be placed in the sample tank 4, and the height from the bottom of the sample tank 4 to the lid 1 is greater than the height of the vial. Specifically, can be that 4 diameters of sample groove are 1mm bigger than freezing and deposit the pipe diameter, and 4 depths of sample groove are 8mm less than freezing and deposit the pipe height, and 4 bottoms of sample groove are to 1 highly than freezing and deposit the pipe height 2mm more than to lid, are convenient for get and take.

In one embodiment, a mark may be provided near each sample well 4 to uniquely correspond to one sample well 4, and the size of the aperture of the sampling hole 2 at least satisfies that the mark can be exposed from the sampling hole 2 when the sampling hole 2 rotates to correspond to the sample well 4. This design for can rotate to sample groove 4 through thief hole 2 when, can directly read corresponding sample groove 4 sign from thief hole 2, with the sample of confirming correspondence, convenient, accurate.

Referring again to fig. 3, in one embodiment, all of the sample wells 4 are distributed in an annular array within the cartridge body 3 except for the blank area. The sample groove 4 has three circles from the center to the outer row altogether, the box cover is equipped with three corresponding sample groove 4 sampling hole 2, and three sampling hole 2 arranges one in proper order from the center to the outer row. Of course, other arrangements are possible, as long as the arrangement of the sample grooves corresponds to the arrangement of the sampling holes.

In one embodiment, the cylindrical cryopreservation box body 3 is filled with polyurethane with heat preservation function, and the box body shell and the box cover 1 are made of wear-resistant and cold-resistant high-density crosslinked polyethylene materials. When in recovery, the cell can be directly transmitted to a cell operation area as a transmission tool. The organic heat-insulating material polyurethane has light weight and good heat-insulating effect, but has the defects of poor aging resistance and large deformation coefficient, and can resist deformation and aging by adding the high-density crosslinked polyethylene shell. In another embodiment, if cost is saved, the freezing storage box body 3 can be selected not to be filled with heat insulation materials and is designed in a grid mode.

The utility model discloses cylindrical freezing box body adopts polyurethane for filling, has better heat preservation effect, and box body shell and lid adopt the resistant high density crosslinked polyethylene material that falls. The box body and the box lid of freezing and depositing can not be dismantled, and the lid card can rotate around the main part on freezing and depositing the box main part, and the accessible rotates the lid and gets from lid hole department and take the freezing and deposit the pipe in the use, has effectively reduced and has got other times that the freezing and depositing pipe exposes under room temperature environment when freezing and depositing the pipe. In addition, every sample groove all has corresponding identification number, rotates the clear show of the hole on the in-process accessible lid, conveniently accurately gets puts the sample. The closed design also greatly reduces the risk that the cryopreserved sample is scattered in the liquid nitrogen tank disorderly due to the fact that the cryopreserved box falls and topples.

Here, the upper, lower, left, right, front, and rear represent only relative positions thereof and do not represent absolute positions thereof. The above only is the embodiment of the present invention, not limiting the patent scope of the present invention, all the equivalent structures or equivalent processes that are used in the specification and the attached drawings or directly or indirectly applied to other related technical fields are included in the patent protection scope of the present invention.

Claims (9)

1. The utility model provides a novel cryopreserved box which characterized in that: the freezing storage box comprises a box body capable of containing a frozen sample, wherein a rotatable box cover is connected to the box body, and a sampling hole is formed in the box cover and used for taking the sample in the box body; sample grooves for containing samples are distributed in the box body, and the opening positions of the sample grooves are matched with the sampling holes, so that when the box cover is rotated, the sampling holes correspond to the openings of the sample grooves, and the samples are taken out.

2. The novel cryopreservation box of claim 1, wherein: the box body and the box cover are in sealed threaded connection, so that the box body and the box cover can be sealed and rotated.

3. The novel cryopreservation box of claim 2, wherein: the junction of box body and lid still is equipped with the buckle to prevent that the lid from excessively rotating to separating with the box body.

4. A novel cryopreservation box as claimed in claim 3 wherein: the box body is internally provided with a blank area which is not provided with a sample groove, so that the box cover can be rotated to enable the sampling hole to be aligned to the blank area when sampling is not needed.

5. The novel cryopreservation box of claim 4, wherein: the sample groove depth is less than the height of the freezing tube which can be placed in the sample groove, and the height from the bottom of the sample groove to the box cover is greater than the height of the freezing tube.

6. The novel cryopreservation box of claim 5, wherein: and an identifier is arranged near each sample groove so as to uniquely correspond to one sample groove through the identifier, and the aperture size of the sampling hole at least meets the requirement that the identifier can be exposed from the sampling hole when the sampling hole rotates to correspond to the sample groove.

7. The novel cryopreservation box of claim 6, wherein: except the blank area, all the sample grooves are distributed in an annular array in the box body.

8. The novel cryopreservation box of claim 7, wherein: the sample groove has three circles from the center to the outer arranging altogether, the box cover is equipped with three corresponding sample groove the thief hatch, three thief hatch arrange into a line from the center to the outer in proper order.

9. The novel cryopreservation box of claim 1, wherein: polyurethane heat-insulating materials are filled in the box body, and high-density crosslinked polyethylene materials are adopted for the box body shell and the box cover.

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