JP3223817U - Multi-organ storage device - Google Patents
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- JP3223817U JP3223817U JP2018600005U JP2018600005U JP3223817U JP 3223817 U JP3223817 U JP 3223817U JP 2018600005 U JP2018600005 U JP 2018600005U JP 2018600005 U JP2018600005 U JP 2018600005U JP 3223817 U JP3223817 U JP 3223817U
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
Abstract
【課題】構造が簡単で、操作が容易で、単離器官を長時間保存することができる多器官保存装置を提供する。【解決手段】多器官保存装置は、肝臓が水浴箱の中に収納されて１つの独立した多器官容器１０８によって異なる器官を保存し、血液が蠕動ポンプ１１６を通過して動力が提供された後に酸素化装置１０３に入り、酸素ボンベ１０２内の酸素が酸素化装置１０３に入って血液と融合する。血液と酸素が十分に酸素化した後、薬物プッシャー１０１は肝臓用薬物又は栄養物質を血管にプッシュして血液と混合して各器官動脈を経て各臓器に入る。血液は各器官を流れた後にフィルタに還流し、血液のブリスター及び不純物などがフィルタに濾過された後に蠕動ポンプ１１６に逆流する。供給管の流量及び流速制御は流量制御弁１０７−１、１０７−２によって調節される。【選択図】図２Provided is a multi-organ storage device that has a simple structure, is easy to operate, and can store an isolated organ for a long time. A multi-organ storage device stores the different organs in a separate bath with a liver stored in a bathing box and after the blood is powered through a peristaltic pump. Entering the oxygenator 103, oxygen in the oxygen cylinder 102 enters the oxygenator 103 and fuses with blood. After the blood and oxygen are sufficiently oxygenated, the drug pusher 101 pushes the liver drug or nutrient into the blood vessel, mixes it with the blood, and enters each organ through each organ artery. The blood flows back to the filter after flowing through each organ, and then flows back to the peristaltic pump 116 after blood blisters and impurities are filtered through the filter. The flow rate and flow rate control of the supply pipe are adjusted by flow rate control valves 107-1 and 107-2. [Selection] Figure 2
Description
本考案は、新規な器官保存システムに関し、特に、多器官保存装置に関するものである。 The present invention relates to a novel organ storage system, and more particularly to a multi-organ storage device.
器官移植は致命的な疾患により機能を喪失した器官を代替し、被移植個体が所望の器官を再獲得し、且つ正常に動作することを可能にすることを目的とする。常用の移植器官として腎臓、心臓、肝臓、膵臓及び膵島、副甲状腺、心肺、骨髄、角膜などがある。器官移植に必要な生体は一般的に他人からのものであり、器官は供給源から切り取られる必要があり、切り取られた単離器官は短い期間内（少なければ数分間、多ければ１時間以下）で死滅してしまい、移植に用いることができなくなる。しかし、このように短い時間内で移植手術を完成することが不能である。したがって、器官が供給源から離れて器官移植手術までもたせるためには、器官の活性を長時間にわたって保持する工夫が必要である。 Organ transplantation is intended to replace organs that have lost function due to a fatal disease, allowing the transplanted individual to reacquire the desired organ and to operate normally. Common transplantation organs include kidney, heart, liver, pancreas and islets, parathyroid gland, cardiopulmonary, bone marrow, cornea and the like. Living organisms required for organ transplantation are generally from others, the organ needs to be cut from the source, and the isolated isolated organ is within a short period (a few minutes at most, less than an hour at most) Will die and cannot be used for transplantation. However, it is impossible to complete a transplant operation in such a short time. Therefore, in order for the organ to move away from the supply source and to have an organ transplant operation, it is necessary to devise a method for maintaining the activity of the organ for a long time.
現在一般的なのは低温保存方法であり、低温静的保存方法は低温によって器官のエネルギー消耗を低下させ、それにより器官保存時間を延長するが、低温はただ細胞の死亡速度を遅くするだけであり、細胞の死亡を防止できず、同時に、低温も組織細胞の損傷を引き起こす可能性もある。 The current common practice is cryopreservation, which reduces the energy consumption of the organ by low temperatures, thereby prolonging organ preservation time, but low temperature only slows the cell death rate, Cell death cannot be prevented, and at the same time, low temperatures can cause tissue cell damage.
特許文献１には低温又は亜常温の腎臓保存装置が開示されており、すでに亜常温で器官保存を行い、腎臓の保存品質を向上させることが考えられる。特許文献２には単離器官を保存する装置及び保存方法が開示されており、それは機械的注入の方式及び膜式酸素化によって単離器官に持続的な養分及び酸素供給を獲得させる。特許文献３には安全防護補強型器官低温機器注入保存装置が開示されており、この装置は低温で器官保存を行い、同時にポンプの様々な制御信号によって異なる注入モードを実現する。特許文献４には移植器官保護袋が開示されており、この装置は構造が簡単であるが、低温でのみ器官を保存でき、酸素及び循環血液を提供できない。また、この特許は１種類の器官のみを保存し、同時に複数又は複数種の器官を保存することができない。 Patent Document 1 discloses a cryopreservation device at a low or sub-normal temperature, and it is considered that organ preservation is already performed at the sub-normal temperature to improve the preservation quality of the kidney. Patent Document 2 discloses an apparatus and a storage method for storing an isolated organ, which allows the isolated organ to obtain a continuous nutrient and oxygen supply by mechanical injection and membrane oxygenation. Patent Document 3 discloses a safety-protection-reinforced organ cryogenic device infusion preservation device, which performs organ preservation at a low temperature and at the same time realizes different infusion modes according to various control signals of the pump. Patent Document 4 discloses a transplanted organ protective bag. This device has a simple structure, but can store an organ only at a low temperature and cannot provide oxygen and circulating blood. Also, this patent stores only one type of organ and cannot store multiple or multiple types of organs at the same time.
特に肝臓などの器官を修復させるためには、長時間の人体器官を保存する必要があり、血液注入に加えて、酸素、栄養成分を供給することで健康的な人体組織を模擬する必要がある。 In particular, in order to repair organs such as the liver, it is necessary to preserve human organs for a long time, and in addition to blood injection, it is necessary to simulate healthy human tissues by supplying oxygen and nutrients .
本考案は、従来技術の不足を解消すべく、構造が簡単で、操作性が良い多器官保存装置を提供することを目的とする。 SUMMARY OF THE INVENTION An object of the present invention is to provide a multi-organ storage device having a simple structure and good operability in order to solve the shortage of the prior art.
上記の目的を達成すべく、本考案は、以下の技術的解決手段を提供する。 In order to achieve the above object, the present invention provides the following technical solutions.
多器官保存設備が取り付けられたカートを含む多器官保存装置であって、前記多器官保存設備は以下を含む：
水浴箱であって、多器官容器が配置され、前記多器官容器内に少なくとも４つの仕切り溝が設けられ、各仕切り溝が、異なる器官を収納するために用いられ、全ての前記仕切り溝の底部が配管によって相互に連通し、いずれかの前記仕切り溝の底部に仕切り溝出口が開けられ、前記多器官容器が容器カバーによって覆われ、前記容器カバーの前後両側がそれぞれ２つの対称的に設けられた容器カバーバックルによって多器官容器に密閉係合し、前記容器カバーが防菌カバーによって覆われ、前記防菌カバーが防菌カバーバックルによって多容器カバーに緊密に係合し、前記水浴箱内に温度センサが取り付けられる。
酸素化装置であって、前記酸素化装置の入口が配管によって蠕動ポンプの出口に連通し、酸素ボンベの出口が酸素配管によって前記酸素化装置の入口に連通し、前記酸素化装置の出口が搬送総配管に接続され、複数の薬物プッシャーの出口がそれぞれ薬物プッシュ配管によって前記搬送総配管に連通し、前記搬送総配管の出口が複数の分岐に分けられ、各分岐に入口流量制御弁が取り付けられ、前記各分岐の出口端が前記水浴箱及び前記多器官容器を貫通し且つ前記多器官容器の各溝内の組織器官動脈血管に一対一に連通し、前記仕切り溝の出口が出口配管に連通し、前記出口配管が前記水浴箱及び前記多器官容器を貫通し且つ出口流量制御弁、フィルタ及び蠕動ポンプが順次接続された出口の出口総管に連通し、前記フィルタの濾過液の出口が前記多器官容器の液面よりも低い。
目盛りを有する少なくとも３つの器官分泌物容器であって、器官分泌物を収集するために用いられ、各器官容器がそれぞれ前記水浴箱を貫通する分泌物出口配管によって前記多器官容器の各仕切り溝の器官に対応する分泌物配管に接続される。
タッチスクリーンであって、前記タッチスクリーンがコントローラに接続され、前記タッチスクリーンによって制御信号を前記コントローラに出力し且つ前記コントローラから出力された信号を読み取り、表示し、前記コントローラが前記蠕動ポンプ、前記入口流量制御弁、前記出口流量制御弁及び前記温度センサにそれぞれ接続され、前記コントローラが前記温度センサの信号を読み取り且つ温度信号に基づいて温度制御信号を前記水浴箱に出力して前記水浴箱内の水を加熱し、前記コントローラが前記入口流量制御弁、前記出口流量制御弁の信号を読み取り、そして回転制御信号を前記蠕動ポンプに出力する。
A multi-organ storage device including a cart with a multi-organ storage facility attached thereto, wherein the multi-organ storage device includes:
A bathing box, in which a multi-organ container is arranged, at least four partition grooves are provided in the multi-organ container, and each partition groove is used to store a different organ, and the bottom of all the partition grooves Are connected to each other by piping, a partition groove outlet is opened at the bottom of one of the partition grooves, the multi-organ container is covered with a container cover, and two front and rear sides of the container cover are provided symmetrically. A container cover buckle is tightly engaged with the multi-organ container, the container cover is covered with the anti-bacterial cover, the anti-bacterial cover is closely engaged with the multi-container cover with the anti-bacterial cover buckle, and the water bath box A temperature sensor is attached.
An oxygenator, wherein the inlet of the oxygenator communicates with the outlet of the peristaltic pump via a pipe, the outlet of the oxygen cylinder communicates with the inlet of the oxygenator via an oxygen pipe, and the outlet of the oxygenator conveys Connected to the total pipe, the outlets of a plurality of drug pushers communicate with the total transport pipe by drug push pipes respectively, the outlet of the total transport pipe is divided into a plurality of branches, and an inlet flow control valve is attached to each branch The outlet end of each branch penetrates the bathing box and the multi-organ container and communicates one-to-one with the tissue organ arterial blood vessel in each groove of the multi-organ container, and the outlet of the partition groove communicates with the outlet pipe. The outlet pipe passes through the bath box and the multi-organ container and communicates with an outlet outlet general pipe to which an outlet flow control valve, a filter, and a peristaltic pump are sequentially connected, and the filtrate is discharged from the filter. There is lower than the liquid level of the multi-organ vessel.
At least three organ secretion containers having graduations, each of which is used to collect organ secretions, and each organ container is connected to each partition groove of the multi-organ container by a secretion outlet pipe penetrating the water bath box; Connected to secretion piping corresponding to the organ.
A touch screen, wherein the touch screen is connected to a controller, outputs a control signal to the controller by the touch screen and reads and displays a signal output from the controller, and the controller includes the peristaltic pump, the inlet The flow rate control valve, the outlet flow rate control valve, and the temperature sensor are connected to each other, and the controller reads the temperature sensor signal and outputs a temperature control signal to the bath box based on the temperature signal. Heating the water, the controller reads the inlet flow control valve and outlet flow control valve signals, and outputs a rotation control signal to the peristaltic pump.
本考案の提供する多器官保存装置は、従来技術と比べ以下の有益な効果を有する。
１、本考案の多器官保存装置は、構造が簡単で、操作しやすく、長時間単離器官を保存でき、ひいては器官を修復できる。
２、本考案の多器官保存装置は肝臓、腎臓、膵臓などの器官を同時に保存及び修復でき、最多で４つの器官を同時に保存でき、器官を最大限に利用できる。
３、本考案の多器官保存装置は蠕動ポンプを制御することによって血液流量供給を行い、流量制御弁は流量及び圧力調節を行い、操作中に適切な血液流量供給を保証でき、酸素、薬物又は栄養物質の供給により、肝臓の保存時間及び修復品質を向上させる。
４、本考案の多器官保存装置はコントローラによってスマートに水浴箱の温度を制御し、必要な温度における肝臓の保存及び修復を保証でき、非正常温度における肝臓の損傷を最大限に防止する。
５、本考案の多器官保存装置はカート形態であり、医師又は医療スタッフが移動させやすく、器官を柔軟に取り出すことができ、さらに生体実験のトレーニングシステムとすることができる。
The multi-organ storage device provided by the present invention has the following beneficial effects as compared with the prior art.
1. The multi-organ storage device of the present invention has a simple structure, is easy to operate, can store an isolated organ for a long time, and thus can repair the organ.
2. The multi-organ storage device of the present invention can simultaneously store and repair organs such as the liver, kidney, and pancreas, and can simultaneously store up to four organs so that the organs can be utilized to the maximum.
3. The multi-organ storage device of the present invention controls the peristaltic pump to supply blood flow, the flow control valve adjusts the flow and pressure, can guarantee the proper blood flow supply during operation, oxygen, drug or Improve liver storage time and repair quality by supplying nutrients.
4. The multi-organ storage device of the present invention controls the temperature of the bath box smartly by the controller, can guarantee the preservation and repair of the liver at the required temperature, and prevent the liver damage at the abnormal temperature to the maximum.
5. The multi-organ storage device of the present invention is in the form of a cart, can be easily moved by a doctor or medical staff, can take out an organ flexibly, and can be used as a training system for biological experiments.
以下、本考案を、具体的な実施例及び図面を参照して詳細に説明する。 Hereinafter, the present invention will be described in detail with reference to specific embodiments and drawings.
図面に示された本考案の多器官保存装置は、カートを含み、器官収集及び搬送過程全体で、スタッフによりカートを押して器官の収集、搬送及び展示、並びに簡単な手術及び実験を行うことができる。このカートには多器官保存設備が取り付けられ、この多器官保存設備は、水浴箱３００、酸素化装置１０３、器官分泌物容器１１５、タッチスクリーン１０５を有する。 The multi-organ storage device of the present invention shown in the drawings includes a cart, and during the organ collection and transport process, the staff can push the cart to collect, transport and display organs, and perform simple surgery and experiments. . A multi-organ storage facility is attached to the cart, and the multi-organ storage facility includes a water bath box 300, an oxygenator 103, an organ secretion container 115, and a touch screen 105.
水浴箱３００は商品化された製品を応用してもよいしカスタマイズされた製品を応用してもよく、大きさが実際の需要に応じて決定されている。水浴箱３００内には１つの多器官容器１０８が配置されており、多器官容器１０８内には少なくとも４つの仕切り溝が設けられ、各仕切り溝が異なる器官を収納するために用いられる。全ての仕切り溝の底部は配管によって相互に連通し、いずれか１つの仕切り溝の底部に１つの仕切り溝出口が開けられ、多器官容器１０８に１つの容器カバー１０９が覆われ、容器カバー１０９の前後両側がそれぞれ２つの対称的に設けられた容器カバーバックル１１３によって多器官容器１０８に密閉係合し、器官の搬送過程で多器官容器カバー１０９から離脱しないよう保証されている。容器カバー１０９の外側は１つの防菌カバー１１１によって覆われ、防菌カバー１１１は防菌カバーバックル１１２によって多容器カバー１０９に緊密に係合し、細菌が多器官容器１０８の内部に入ることを防止する。水浴箱３００には温度センサが取り付けられる。 The bathing box 300 may be a commercialized product or a customized product, and the size is determined according to actual demand. One multi-organ container 108 is disposed in the bathing box 300, and at least four partition grooves are provided in the multi-organ container 108, and each partition groove is used to store a different organ. The bottoms of all the partition grooves communicate with each other by pipes, one partition groove outlet is opened at the bottom of any one partition groove, one container cover 109 is covered with the multi-organ container 108, and the container cover 109 Two symmetrically provided container cover buckles 113 on both the front and rear sides are hermetically engaged with the multi-organ container 108 and are guaranteed not to be detached from the multi-organ container cover 109 in the course of organ transportation. The outside of the container cover 109 is covered by a single antibacterial cover 111, and the antibacterial cover 111 is closely engaged with the multicontainer cover 109 by the antibacterial cover buckle 112, and bacteria enter the inside of the multi-organ container 108. To prevent. A temperature sensor is attached to the water bath box 300.
酸素化装置１０３においては、入口が配管によって蠕動ポンプ１１６の出口に連通し、１つの酸素ボンベ１０２の出口が酸素配管によって酸素化装置１０３の入口に連通する。酸素化装置１０３の出口は１つの搬送総配管に接続され、複数の薬物プッシャー１０１の出口はそれぞれ薬物プッシュ配管によって前記搬送総配管に連通し、前記搬送総配管の出口は複数の分岐に分けられ、各分岐に１つの入口流量制御弁１０７−１が取り付けられ、各分岐の出口端は水浴箱３００及び多器官容器１０８を貫通し且つ多器官容器１０８の各溝内の組織器官動脈血管に一対一に連通し、前記仕切り溝の出口は出口配管に連通し、前記出口配管は水浴箱３００及び多器官容器１０８を貫通し且つ出口流量制御弁１０７−２、フィルタ１２０及び蠕動ポンプ１１６が順次接続された出口の出口総管に連通する。フィルタ１２０の取り付けは少し低くすべきであり、これにより、フィルタ１２０の濾過液の出口が多器官容器１０８の液面よりも低いことが確保される。入口流量制御弁１０７−１は手動調節又は電動調節によって血液流量を制御することができる。 In the oxygenator 103, the inlet communicates with the outlet of the peristaltic pump 116 through a pipe, and the outlet of one oxygen cylinder 102 communicates with the inlet of the oxygenator 103 through an oxygen pipe. The outlet of the oxygenator 103 is connected to one transport total pipe, the outlets of a plurality of drug pushers 101 communicate with the transport total pipe by drug push pipes, respectively, and the outlet of the transport total pipe is divided into a plurality of branches. One inlet flow control valve 107-1 is attached to each branch, and the outlet end of each branch passes through the water bath 300 and the multi-organ container 108 and is paired with the tissue organ artery blood vessel in each groove of the multi-organ container 108. The outlet of the partition groove communicates with an outlet pipe, the outlet pipe passes through the water bath 300 and the multi-organ container 108, and the outlet flow control valve 107-2, the filter 120 and the peristaltic pump 116 are sequentially connected. Communicated with the outlet outlet pipe. The attachment of the filter 120 should be slightly lower, which ensures that the filtrate outlet of the filter 120 is lower than the liquid level of the multi-organ container 108. The inlet flow control valve 107-1 can control the blood flow rate by manual adjustment or electric adjustment.
器官分泌物容器１１５は、少なくとも３つ設けられており、それぞれ目盛りを有する。器官分泌物容器１１５は、尿液、胆汁、膵液などの器官分泌物を収集するために用いられ、各器官容器はそれぞれ水浴箱３００を貫通する分泌物出口配管によって多器官容器１０８の各仕切り溝の器官の対応する分泌管（例えば胆汁を分泌する胆管など）に接続される。 At least three organ secretion containers 115 are provided, each having a scale. The organ secretion container 115 is used to collect organ secretions such as urine fluid, bile, pancreatic juice, etc., and each organ container is divided into each partition groove of the multi-organ container 108 by a secretion outlet pipe penetrating the water bath 300. To the corresponding secretory tract of the organ (eg bile duct secreting bile).
タッチスクリーン１０５はコントローラ２００に接続され、制御信号をコントローラ２００に出力し且つコントローラ２００から出力された信号を読み取り、表示する。コントローラ２００は蠕動ポンプ１１６、入口流量制御弁１０７−１、出口流量制御弁１０７−２及び温度センサにそれぞれ接続されている。コントローラ２００は温度センサの信号を読み取り且つ温度信号に基づいて温度制御信号を水浴箱３００に出力して水浴箱３００内の水を加熱する。コントローラ２００は入口流量制御弁１０７−１及び出口流量制御弁１０７−２の信号を読み取り、そして回転制御信号を蠕動ポンプ１１６に出力する。 The touch screen 105 is connected to the controller 200, outputs a control signal to the controller 200, and reads and displays a signal output from the controller 200. The controller 200 is connected to the peristaltic pump 116, the inlet flow control valve 107-1, the outlet flow control valve 107-2, and the temperature sensor. The controller 200 reads the temperature sensor signal and outputs a temperature control signal to the water bath box 300 based on the temperature signal to heat the water in the water bath box 300. The controller 200 reads the signals of the inlet flow control valve 107-1 and the outlet flow control valve 107-2, and outputs a rotation control signal to the peristaltic pump 116.
本考案の好適な実施形態として、前記カートはカートの底板に設けられた上ステージ１２４を含み、上ステージ１２４の左側にハンドル１１０が固定されており、前記カートの底板に４つの車輪１１４が接続されている。上ステージ１２４の中間及び右側にそれぞれ中間仕切り板１２１及び右側仕切り板１２２が取り付けられ、複数の薬物プッシャー１０１（薬物プッシャー１０１の取り付け数は実際の需要に応じて決定される）及び酸素ボンベ１０２が右側仕切り板１２２の右側の上ステージ１２４に取り付けられ、酸素ボンベ１０２が酸素ボンベ固定バンド１２３によって右側仕切り板１２２に固定され、これにより酸素ボンベ１０２が動かないように固定される。蠕動ポンプ１１６、酸素化装置１０３及びフィルタ１２０が中間仕切り板１２１と右側仕切り板１２２との間に前後に順次設けられ、蠕動ポンプ１１６が上ステージ１２４に固定され且つ中間仕切り板１２１及び右側仕切り板１２２によってクランプされて揺れが制限される。酸素化装置１０３は、Ｕ形の酸素化装置接続板１０４に吊り下げられて固着され、酸素化装置接続板１０４のＵ形の両端がそれぞれ中間仕切り板１２１及び右側仕切り板１２２に固定される。フィルタ１２０がフィルタホルダ１１８によって中間仕切り板１２１に固着され、入口流量制御弁１０７−１が中間仕切り板１２１の上面に固定して取り付けられ、水浴箱３００が中間仕切り板１２１の左側の上ステージ１２４に固定して取り付けられ、器官分泌物容器１１５が多器官容器１０８の前側の上ステージ１２４に取り付けられる。タッチスクリーン１０５がタッチスクリーン接続ホルダ１０６によって上ステージ１２４の後側に固定される。 As a preferred embodiment of the present invention, the cart includes an upper stage 124 provided on the bottom plate of the cart, a handle 110 is fixed to the left side of the upper stage 124, and four wheels 114 are connected to the bottom plate of the cart. Has been. An intermediate partition plate 121 and a right partition plate 122 are attached to the middle and right sides of the upper stage 124, respectively, and a plurality of drug pushers 101 (the number of drug pushers 101 attached is determined according to actual demand) and an oxygen cylinder 102 are provided. It is attached to the upper stage 124 on the right side of the right partition plate 122, and the oxygen cylinder 102 is fixed to the right partition plate 122 by an oxygen cylinder fixing band 123, thereby fixing the oxygen cylinder 102 so as not to move. The peristaltic pump 116, the oxygenator 103, and the filter 120 are sequentially provided between the intermediate partition plate 121 and the right partition plate 122 in the front-rear direction, the peristaltic pump 116 is fixed to the upper stage 124, and the intermediate partition plate 121 and the right partition plate are provided. Clamping by 122 restricts shaking. The oxygenator 103 is suspended and secured to the U-shaped oxygenator connection plate 104, and both U-shaped ends of the oxygenator connection plate 104 are fixed to the intermediate partition plate 121 and the right partition plate 122, respectively. The filter 120 is fixed to the intermediate partition plate 121 by the filter holder 118, the inlet flow control valve 107-1 is fixedly attached to the upper surface of the intermediate partition plate 121, and the water bath 300 is located on the upper stage 124 on the left side of the intermediate partition plate 121. The organ secretion container 115 is attached to the upper stage 124 on the front side of the multi-organ container 108. The touch screen 105 is fixed to the rear side of the upper stage 124 by the touch screen connection holder 106.
入口流量制御弁１０７−１及び出口流量制御弁１０７−２は機械式手動弁を採用するか、又は電動制御弁を採用する。 The inlet flow control valve 107-1 and the outlet flow control valve 107-2 employ a mechanical manual valve or an electric control valve.
図２及び図３は多器官保存装置の原理模式図であり、各器官が多器官容器１０８内に収納され、血液が蠕動ポンプ１１６の動力により酸素化装置１０３に入り、酸素ボンベ１０２内の酸素が酸素化装置１０３に入ることで血液の酸素化が行われる。次いで、薬物プッシャー１０１によってプッシュされた薬物又は栄養物質が、酸素化された血液と混合された後に各臓器の内部に入る。各器官に入る血液の流速及び流量がそれぞれの入口流量制御弁１０７−１によって制御され、血液が各器官を流れた後にフィルタ１２０に還流し、還流の流速及び圧力が出口流量制御弁１０７−２によって調節され、血液内のブリスター及び不純物などがフィルタ１２０に濾過された後に蠕動ポンプ１１６に逆流する。さらに、使用過程で各器官に血液を送るための配管に圧力及び流速センサを設け、その圧力及び流速を測定し、それらをコントローラ２００に伝送するようにしてもよい。また、水浴箱３００の温度信号を前記圧力及び流速センサを介してコントローラ２００に入力させ、コントローラ２００が温度、圧力、流速のパラメータや医師の操作に基づいて水浴箱３００内の水の温度及び蠕動ポンプ１１６の回転数を調節してもよい。医師はタッチスクリーン１０５によって多器官保存装置を設定でき及び各部材の運転状況の情報を見ることができる。 2 and 3 are schematic diagrams of the principle of the multi-organ storage device. Each organ is housed in a multi-organ container 108, blood enters the oxygenator 103 by the power of the peristaltic pump 116, and oxygen in the oxygen cylinder 102 is obtained. Enters the oxygenator 103, and oxygenation of blood is performed. Then, the drug or nutrient pushed by the drug pusher 101 is mixed with oxygenated blood and then enters the inside of each organ. The flow rate and flow rate of the blood entering each organ is controlled by the respective inlet flow control valve 107-1, and the blood flows back to the filter 120 after flowing through each organ. The flow rate and pressure of the return flow are the outlet flow control valve 107-2. The blisters and impurities in the blood are filtered by the filter 120 and then flow back to the peristaltic pump 116. Furthermore, a pressure and flow rate sensor may be provided in a pipe for sending blood to each organ in the course of use, and the pressure and flow rate may be measured and transmitted to the controller 200. In addition, the temperature signal of the bathing box 300 is input to the controller 200 via the pressure and flow rate sensors, and the controller 200 detects the temperature and perturbation of the water in the bathing box 300 based on the temperature, pressure, flow rate parameters and the operation of the doctor. The rotational speed of the pump 116 may be adjusted. The doctor can set the multi-organ storage device through the touch screen 105 and can view information on the operation status of each member.
以上で説明した実施形態は例示に過ぎず、本考案はこれに限定されるものではない。当業者であれば本考案の目的を逸脱しない範囲内で本考案の技術的スキーム及び実施形態と同様の、創造的設計がない他の形態の構造、伝達機構、設置および接続方法を採用することができるような、添付の考案請求の範囲、及び全ての変更、等価の置換及び改良は、本発明の保護範囲に入るものとする。 Embodiment described above is only an illustration and this invention is not limited to this. Those skilled in the art will adopt other forms of structures, transmission mechanisms, installation and connection methods without creative design similar to the technical schemes and embodiments of the present invention without departing from the purpose of the present invention. It is intended that the appended claims and all modifications, equivalent substitutions and improvements be included within the protection scope of the present invention.
Claims (4)
多器官容器が配置され、前記多器官容器内に少なくとも４つの仕切り溝が設けられ、各仕切り溝が異なる器官を収納するために用いられ、全ての前記仕切り溝の底部が配管によって相互に連通し、いずれかの前記仕切り溝の底部に仕切り溝出口が開けられ、前記多器官容器が容器カバーによって覆われ、前記容器カバーの前後両側がそれぞれ２つの対称的に設けられた容器カバーバックルによって多器官容器に密閉係合し、前記容器カバーが防菌カバーによって覆われ、前記防菌カバーが防菌カバーバックルによって多容器カバーに緊密に係合し、内部に温度センサが取り付けられた水浴箱と、
酸素化装置であって、前記酸素化装置の入口が配管によって蠕動ポンプの出口に連通し、酸素ボンベの出口が酸素配管によって前記酸素化装置の入口に連通し、前記酸素化装置の出口が搬送総配管に接続され、複数の薬物プッシャーの出口がそれぞれ薬物プッシュ配管によって前記搬送総配管に連通し、前記搬送総配管の出口が複数の分岐に分けられ、各分岐に入口流量制御弁が取り付けられ、前記各分岐の出口端が前記水浴箱及び前記多器官容器を貫通し且つ前記多器官容器の各溝内の組織器官動脈血管に一対一に連通し、前記仕切り溝の出口が出口配管に連通し、前記出口配管が前記水浴箱及び前記多器官容器を貫通し且つ出口流量制御弁、フィルタ及び蠕動ポンプが順次接続された出口の出口総管に連通し、前記フィルタの濾過液の出口が前記多器官容器の液面よりも低い酸素化装置と、
器官分泌物を収集するために用いられ、各器官容器がそれぞれ前記水浴箱を貫通する分泌物出口配管によって前記多器官容器の各仕切り溝の器官に対応する分泌物配管に接続される、目盛りを有する少なくとも３つの器官分泌物容器と、
コントローラに接続され、制御信号を前記コントローラに出力し且つ前記コントローラから出力された信号を読み取り、表示し、前記コントローラが前記蠕動ポンプ、前記入口流量制御弁、前記出口流量制御弁及び前記温度センサにそれぞれ接続され、前記コントローラが前記温度センサの信号を読み取り且つ温度信号に基づいて温度制御信号を前記水浴箱に出力して前記水浴箱内の水を加熱し、前記コントローラが前記入口流量制御弁、前記出口流量制御弁の信号を読み取り、そして回転制御信号を前記蠕動ポンプに出力するタッチスクリーンと、
を備えることを特徴とする、
多器官保存装置。 A multi-organ storage device comprising a cart with a multi-organ storage device attached thereto, wherein the multi-organ storage device includes:
A multi-organ container is disposed, and at least four partition grooves are provided in the multi-organ container, and each partition groove is used to store different organs, and the bottoms of all the partition grooves communicate with each other by piping. A partition groove outlet is opened at the bottom of any of the partition grooves, the multi-organ container is covered with a container cover, and the container cover buckle is provided with two symmetrically provided container cover buckles on each of the front and rear sides of the container cover. A water bath box in which the container cover is tightly engaged with the container, the container cover is covered by the antibacterial cover, the antibacterial cover is closely engaged with the multi-container cover by the antibacterial cover buckle, and a temperature sensor is attached inside;
An oxygenator, wherein the inlet of the oxygenator communicates with the outlet of the peristaltic pump via a pipe, the outlet of the oxygen cylinder communicates with the inlet of the oxygenator via an oxygen pipe, and the outlet of the oxygenator conveys Connected to the total pipe, the outlets of a plurality of drug pushers communicate with the total transport pipe by drug push pipes respectively, the outlet of the total transport pipe is divided into a plurality of branches, and an inlet flow control valve is attached to each branch The outlet end of each branch penetrates the bathing box and the multi-organ container and communicates one-to-one with the tissue organ arterial blood vessel in each groove of the multi-organ container, and the outlet of the partition groove communicates with the outlet pipe. The outlet pipe passes through the bath box and the multi-organ container and communicates with an outlet outlet general pipe to which an outlet flow control valve, a filter, and a peristaltic pump are sequentially connected, and the filtrate is discharged from the filter. There said multiorgan container lower oxygenation apparatus the liquid level,
A scale used for collecting organ secretions, each organ container being connected to a secretion pipe corresponding to an organ in each partition groove of the multi-organ container by a secretion outlet pipe penetrating each water bath box. Having at least three organ secretion containers;
Connected to the controller, outputs a control signal to the controller and reads and displays the signal output from the controller, the controller to the peristaltic pump, the inlet flow control valve, the outlet flow control valve and the temperature sensor Connected to each other, the controller reads the temperature sensor signal and outputs a temperature control signal to the bath box based on the temperature signal to heat the water in the bath box, and the controller controls the inlet flow control valve, A touch screen that reads the signal of the outlet flow control valve and outputs a rotation control signal to the peristaltic pump;
Characterized by comprising,
Multi-organ storage device.
請求項１に記載の多器官保存装置。 The cart includes an upper stage provided on the bottom plate of the cart, a handle is fixed to the left side of the upper stage, four wheels are connected to the bottom plate of the cart, and each of the middle is on the middle and right side of the upper stage. A partition plate and a right partition plate are attached, a plurality of drug pushers and an oxygen cylinder are attached to the upper stage on the right side of the right partition plate, and the oxygen cylinder is fixed to the right partition plate by an oxygen cylinder fixing band, The pump, the oxygenator and the filter are sequentially provided between the intermediate partition plate and the right partition plate, and the peristaltic pump is fixed to the upper stage and clamped by the intermediate partition plate and the right partition plate And the swinging is restricted, and the oxygenator is suspended from a U-shaped oxygenator connecting plate and fixed. U-shaped ends of the oxygenator connection plate are fixed to the intermediate partition plate and the right partition plate, the filter is fixed to the intermediate partition plate by a filter holder, and the inlet flow control valve is connected to the intermediate partition plate. The water bath box is fixedly attached to the upper stage on the left side of the intermediate partition plate, and the organ secretion container is attached to the upper stage on the front side of the multi-organ container. The touch screen is fixed to the rear side of the upper stage by a touch screen connection holder,
The multi-organ storage device according to claim 1.
請求項１又は２に記載の多器官保存装置。 The inlet flow control valve and the outlet flow control valve are mechanical manual valves,
The multi-organ storage apparatus according to claim 1 or 2.
請求項１又は２に記載の多器官保存装置。 The inlet flow control valve and the outlet flow control valve are electric control valves,
The multi-organ storage apparatus according to claim 1 or 2.
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| CN211407436U (en) * | 2019-03-22 | 2020-09-04 | 天一阁医疗科技(广州)有限公司 | Mechanical perfusion preservation device for organism organs |
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