CN105165801B - A kind of portable liver room temperature save set - Google Patents

A kind of portable liver room temperature save set Download PDF

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Publication number
CN105165801B
CN105165801B CN201510540702.3A CN201510540702A CN105165801B CN 105165801 B CN105165801 B CN 105165801B CN 201510540702 A CN201510540702 A CN 201510540702A CN 105165801 B CN105165801 B CN 105165801B
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China
Prior art keywords
liver
space
water bath
cover
room temperature
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CN201510540702.3A
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Chinese (zh)
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CN105165801A (en
Inventor
沈中阳
郑虹
邓永林
潘澄
高伟
刘蕾
史源
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Tianjin First Central Hospital
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Tianjin First Central Hospital
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Publication of CN105165801A publication Critical patent/CN105165801A/en
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Publication of CN105165801B publication Critical patent/CN105165801B/en
Expired - Fee Related legal-status Critical Current
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Abstract

A kind of portable liver room temperature save set has the water bath for placing liver being arranged in babinet, is respectively arranged in babinet:The filter of liver is connected by return duct, one input terminal connects the output end of filter by peristaltic pump with diversion pipe, another input terminal connects the oxygenation device of oxygen cylinder by oxygen hose, the output of oxygenation device into the flow electrically-controlled valve in flow tube into flow tube by connecting liver with being arranged, the output end positioned at oxygenation device between the input terminal of flow electrically-controlled valve into also connecting drug pusher by pipe joint and the drug catheter being connected with pipe joint in flow tube, the bile container being connected with liver is additionally provided in water bath, be additionally provided in babinet respectively with peristaltic pump, the controller that flow electrically-controlled valve is connected with the heating device in water bath, and the accumulator for providing power supply to controller.The configuration of the present invention is simple, it is easy to operate, in vitro liver can be preserved for a long time, or even can repair liver.

Description

A kind of portable liver room temperature save set
Technical field
The present invention relates to a kind of liver room temperature save sets.More particularly to a kind of portable liver room temperature save set.
Background technology
Since Thomas professors Starzl in 1963 successfully complete the 1st Clinical Liver Transplantation, Technology of Liver Transplantation in China development Rapidly, become the main means for the treatment of End-stage liver disease.The whole world is increasingly serious for liver shortage situation at present, this problem is in China Especially prominent, there are about 1,500,000 patients to need organ transplant every year in China, and carries out organ transfer operation only 10,000 or so every year, A large amount of patients are dead because of donor organ shortage.With the continuous improvement of Chinese society civilization degree, the donor in Newgate saint source Organ number falls sharply, and heart death is contributed (donation after cardiac death, DCD) and supplied as China's organ transplant Person's main source becomes the main path for solving China's donor organ critical shortage.It is counted according to Chinese visible human organ donation center, By on 03 01st, 2015 registered 35290 people of organ donation volunteer, witnesses and successfully contributed 3188, given treatment to organ Failure patients 8866.But 13.4 hundred million All population capacities of opposite China, horizontal far below World Developed Countries, still having greatly can For.
It is that DCD donor organs are second-rate, and lack science currently, seriously perplexing the problem of China's DCD organ donations Appraisal procedure, not only seriously affect patient's prognosis, but also cause practical efficiency very low.For liver not only by the long period Low perfusion, Warm ischemia injury, and Cryopreservation Injury is undergone, lead to primary idle, the function delay of liver transplantation in world wide Restore incidence to gradually increase.The simple Cord blood technology of UW liquid that the eighties in last century occurs once was considered as Clinical Liver Transplantation hair The milestone of exhibition, but UW Cord blood technologies itself can not accurately assess the vigor state for liver, will also be subjected to low temperature injury, It is even more impossible to carry out injury repair, the ever-increasing clinical demand of the Marginal donor livers such as DCD cannot be satisfied at present.
As the novel mechanical Perfusion preservation technology for substituting the simple Cord blood of UW liquid, according to the maintenance temperature of perfusion system Difference can be divided into hypothermic machine perfusion (hypothermic machine perfusion, HMP) and room temperature machine perfusion (normothermic machine perfusion, NMP).HMP is conducive to the thorough lavation of intraorganic blood, is conducive to remove Or dilution metabolic waste, while organ being constantly provided and is metabolized required energy, graft function delay can be significantly reduced Incidence, effect are better than simple Cord blood.HMP technologies originate in the sixties, during which due to equipment and technology complexity etc. It lies on the table.Now with increasingly serious for liver shortage situation, extending for the liver holding time, DCD increases for liver and Marginal donor liver, with And HMP technologies, in the success in kidney transplant field, HMP technologies become liver transfer operation research hotspot again.
However NMP keeps normal metabolism and tissue self-repairing capability closer to physiological status.It is supplied with lasting maintenance Liver blood vessel bed is open;Sufficient energy substrate and oxygen supply are provided, ensure metabolic demand decreased under low-temperature condition; Metabolite and toxin are removed or diluted in time;It effectively removes in liver the advantages that remaining microthrombus.But NMP skills at present The defects of that there are equipment is huge for art, technical sophistication limits the clinical application of NMP, therefore it is ten to develop portable, easy equipment Divide important.
External NMP core technologies are also concentrated mainly on American-European a small number of developed countries.Such as Canada's EVLP systems, Britain Organ-OX systems, U.S.'s Transmedic systems, LifePort systems, Dutch Organ-Assist systems etc..It is badly in need of in China Liver room temperature preserves and recovery technique, but since such device technical difficulty is big, the country there is no such product, belongs to blank neck Domain.Start within 2012, country starts 863 projects and " establishes complete organ preservation and external reparation system and heart death The assessment of donated organs, screening criteria " (project number:2012AA021001), which fully considers and faces based on China's actual conditions Bed demand, closely surrounds the core for improving Donor liver quality, and by a large amount of zoopery, the discarded organ experiment of clinic is abandoned often The complicated huge defect of warm machine perfusion technical equipment, successfully develops portable, simple and stable, intelligentized device.
Patent 201410384703.9 discloses the kidney being kept in existence device of a kind of low temperature or subnormal temperature, has begun to examine Consider and carry out organ preservation under subnormal temperature, improves the preservation quality of kidney, but without being used for Liver Allograft Preservation.Patent 201410016261.2 disclose a kind of device and store method preserving isolated organ, by way of machine perfusion and film The conjunction of formula oxygen makes isolated organ obtain lasting nutrient and oxygen supply, however, its is simple in structure, each device is connected, fixed And the poor reliability in structure, function are difficult to ensure.It is enhanced that patent 201510085562.5 discloses a kind of security protection Organ hypothermia machine perfusion save set, the device carry out organ preservation, while the various control signals for passing through pump at low temperature Realize different fill-up modes.However, the structure type is simple, each two pieces be fixedly connected and it is realisation poor.Specially Sharp 201310723787.X discloses a kind of transplant organ protective bag, and the apparatus structure is simple, however the device also can only be low Temperature is lower to carry out organ preservation, can not provide oxygen and blood circulation.
Invention content
The technical problem to be solved by the invention is to provide a kind of portable liver simple in structure, that operability is good is normal Warm save set.
The technical solution adopted in the present invention is:A kind of portable liver room temperature save set, includes babinet and setting In babinet for placing the water bath of liver, be respectively arranged in the babinet:The liver is connected by return duct Filter for being filtered to the venous blood that liver flows out, an input terminal connect filtering with diversion pipe by peristaltic pump The output end of device, another input terminal connect the oxygen conjunction that oxygen cylinder is used to carry out oxygen and venous blood oxygen conjunction by oxygen hose Device, the output of the oxygenation device by connecting liver in the flow electrically-controlled valve into flow tube with being arranged into flow tube, Positioned at oxygenation device output end between the input terminal of flow electrically-controlled valve into flow tube also by a pipe joint and with Drug pusher of the connected drug catheter connection of pipe joint for conveying drug or nutriment to liver, the water-bath It is additionally provided with the bile container being connected for receiving the bile that hepatic secretion goes out with the liver in case, is gone back in the babinet It is provided with the controller being connected respectively with the heating device in the peristaltic pump, flow electrically-controlled valve and water bath, and is used for The accumulator of power supply is provided to controller.
Temperature, the blood stream being connected for showing water bath with the controller are provided on the babinet front panel The display screen of speed, blood flow parameter.
The pipe joint is a triple valve or the magnet ring fast junction apparatus that is connected for blood vessel.
The babinet includes bottom plate, the right-hand apron being fixedly installed to respectively by screw on bottom plate and left side gear Plate, the right-hand apron and left side baffle will be divided into rightward space, central space and leftward space, institute above the bottom plate The front for stating central space sets up separately and is equipped with water bath, and the rear part of the central space constitutes rear space, wherein the right side It is corresponding on side space, leftward space, water bath and rear space to be provided with right cover, left cover, upper cover and rear cover.
The right cover is opening a slot for being easy to open right cover U on the edge at bottom plate.
It is provided in the rightward space:By screw, the fixation band that is bonded or is weldingly fixed on bottom plate, pass through The peristaltic pump on the bottom plate, the oxygenation device being respectively fixedly connected on the right-hand apron and filtering is arranged in fixed band Device, the diversion pipe for conveying venous blood being connected between filter, peristaltic pump and oxygenation device pass through to weld, be bonded Or screw is connected to the fixed chuck that the fixation takes and is located on the peristaltic pump, is also extended through on the right-hand apron There is the front end of oxygen cylinder, the oxygen discharge of the oxygen cylinder connects the oxygen input port of oxygenation device by oxygen hose, described Filter pass through through the return duct of the right-hand apron connection be located at water bath in liver.
It is provided in the leftward space:The accumulator and use for providing power supply to controller being fixed on bottom plate Left side is sequentially passed through in the drug catheter of the drug pusher for conveying drug or nutriment to liver, connection drug pusher Baffle and right-hand apron by pipe joint connect oxygenation device output end into flow tube.
It is respectively arranged with controller and oxygen cylinder in the rear space, wherein the controller is by running through left side The conducting wire connection of baffle is located at the accumulator in leftward space, and the front end of the oxygen cylinder is connected through right-hand apron by oxygen hose Connect the oxygenation device in rightward space.
Upper cover for sealing water bath is connected through the hinge in the back side panel of water bath, for closing rightward space Right cover is connected through the hinge on right-hand apron, and the left cover for closing leftward space is connected through the hinge in left side baffle.
The rear cover is the cover board of L-type, and the bottom edge of the cover board of L-type is hinged by hinge and bottom rear edge, described The heat emission hole being also provided with for cooling down to controller is covered afterwards.
A kind of portable liver room temperature save set of the present invention, has the advantages that:
1. the liver room temperature save set of the present invention, simple in structure, easy to operate, in vitro liver can be preserved for a long time, Liver even can be repaired.
2. the liver room temperature save set of the present invention carries out blood flow and pressure adjusting by single pump, can operate In can ensure the supply of suitable blood flow, supplied by oxygen, drug or nutriment, increase the Liver Allograft Preservation time with And repairing quality.
3. using PLC automatic control system first in the world:This patent pressure and flow number feed back to PLC controller, The principles such as PLC controller is limited according to maximum pressure, minimum flow ensures, aeroembolism detection is shut down, automatically control centrifugal pump motor Rotating speed, and control the realization of portal vein electronics pressure reducing valve and automatically control.
4. the liver room temperature save set of the present invention can ensure liver by the temperature of controller intelligent control water bath It is dirty to be preserved and repaired at normal temperatures, the damage that liver is caused under low temperature condition is prevented to the greatest extent.
5. part NMP devices (Liver assist) freely pass back into open storage blood pool using inferior caval vein, part fills It sets (OrganX) and uses inferior vena cava cannula, close the closed circulation of blood bag.And both our device fusions advantage, it is not only close It closes and preserves blood circulation reduction infection risk, and the non-steeped preservation of liver, and vascular catheterization is avoided to damage.Adequate drainage system System, on liver, dual adequate drainage under liver, the blood in unimpeded drainage blood pool avoids vena cave direct cannulation from draining, shift in position Or rotating speed increases the suction being easy to cause, and causes aeroembolism, or even can realize in filling process and be split liver from operation.
6. the present apparatus uses narrow body blood pool container, the low wind for increasing return duct sucking air of lower vessel level is avoided Danger increases travelling performance.
Description of the drawings
Fig. 1 is the portable liver room temperature save set overall structure diagram of the present invention;
Fig. 2 is the portable liver room temperature save set principle schematic of the present invention;
Fig. 3 is one of pipeline structure schematic diagram on the right side of the portable liver room temperature save set of the present invention;
Fig. 4 is two of pipeline structure schematic diagram on the right side of the portable liver room temperature save set of the present invention;
Fig. 5 is the portable liver room temperature save set left side structure schematic diagram of the present invention;
Fig. 6 is the portable liver room temperature save set upper structure schematic diagram of the present invention;
Fig. 7 is the portable liver room temperature save set rear structure schematic diagram of the present invention.
Wherein:
1:Left cover 2:Upper cover
3:Rear cover 4:Right cover
5:Display screen 6:Pipe joint
7:Return duct 8:Filter
9:Oxygenation device 10:Diversion pipe
11:Peristaltic pump 12:Fixed band
13:Into flow tube 14:Oxygen cylinder
15:Oxygen hose 16:Fixed chuck
17:Drug pusher 18:Drug catheter
19:Accumulator 20:Water bath
21:Controller 22:Bottom plate
23:Right-hand apron 24:Left side baffle
25:Flow electrically-controlled valve 26:Bile container
27:Liver 28:Rightward space
29:Leftward space 30:Rear space
31:Heat emission hole 32:U slots
Specific implementation mode
A kind of portable liver room temperature save set of the present invention is described in detail with reference to embodiment and attached drawing.
As shown in Figure 1 and Figure 2, a kind of portable liver room temperature save set of the invention includes babinet and is arranged in case The internal water bath 20 for placing liver 27, liver 27 is by an independent plastic casing or polybag etc. and waters Isolation is stored in water bath 20.It is respectively arranged in the babinet:By return duct 7 connect the liver 27 for pair The filter 8 that the venous blood that liver 27 flows out is filtered, an input terminal were connected by peristaltic pump 11 and diversion pipe 10 The output end of filter 8, another input terminal connect oxygen cylinder 14 by oxygen hose 15 and are used to oxygen and venous blood carrying out oxygen The oxygenation device 9 of conjunction, the output of the oxygenation device 9 is by into flow tube 13 and being arranged automatically controlled into the flow in flow tube 13 described Valve 25 connects liver 27, the output end positioned at oxygenation device 9 between the input terminal of flow electrically-controlled valve 25 into flow tube 13 Also by a pipe joint 6 and with pipe joint 6 be connected drug catheter 18 connect for liver 27 conveying drug or The drug pusher 17 of nutriment, the magnet ring that the pipe joint 6 is a triple valve or connects for blood vessel are quick Docking facilities are (if number of patent application is 201510382795.1 or number of patent application is magnet ring disclosed in 201510382849.4 Pairing mode).The bile for being connected with the liver 27 and being secreted out of for receiving liver 27 is additionally provided in the water bath 20 Bile container 26, be additionally provided in the babinet respectively with the peristaltic pump 11, flow electrically-controlled valve 25 and water bath 20 In the connected controller 21 of heating device, and the accumulator 19 for providing power supply to controller 21.Before the babinet Temperature, velocity of blood flow, the blood flow parameter being connected with the controller 21 for showing water bath 20 are provided on panel Display screen 5.
As shown in Figure 1, the babinet includes bottom plate 22, it is fixedly installed to the right side on bottom plate 22 respectively by screw 22 top of the bottom plate is divided into rightward space by baffle 23 and left side baffle 24, the right-hand apron 23 and left side baffle 24 28, central space and leftward space 29, the front of the central space, which is set up separately, is equipped with water bath 20, the rear portion of the central space Point constitute rear space 30, wherein on the rightward space 28, leftward space 29, water bath 20 and rear space 30 respectively It is corresponding to be provided with right cover 4, left cover 1, upper cover 2 and rear cover 3.Right cover 4, left cover 1, upper cover 2 and the rear cover 3 can be beaten respectively It opens, the devices such as the disposable instrument of placement or oxygen cylinder before being easy to use.The right cover 4 is opened on the edge at bottom plate 22 One U slot 32, is easy to open right cover 4.
As shown in Figure 3, Figure 4, it is provided in the rightward space 28:By screw, it is bonded or is weldingly fixed on bottom Fixation band 12 on plate 22, the peristaltic pump 11 being arranged on the bottom plate 22 by fixed band 12, passes through the piece that is rigidly connected respectively It is screwed the oxygenation device 9 being connected on the right-hand apron 23 and filter 8, is connected to filter 8,11 and of peristaltic pump The diversion pipe 10 for conveying blood between oxygenation device 9 with welding, bonding or screw by being connected to the fixed band Fixed chuck 12A on 12 is located on the peristaltic pump 11, and fixed band 12 can regard the practical fixation to peristaltic pump 11 Degree uses one or more.The front end of oxygen cylinder 14 is also extended through on the right-hand apron 23, the oxygen cylinder 14 Oxygen discharge connects the oxygen input port of oxygenation device 9 by oxygen hose 15, and the filter 8 is by running through the right side The connection of return duct 7 of baffle 23 is located at the liver 27 in water bath 20.The right cover 4 is connected through the hinge in right-hand apron 23 On, and for closing rightward space 28.
As shown in figure 5, being provided in the leftward space 29:It is fixed by screws on bottom plate 22 and is used for control Device 21 provides the accumulator 19 of power supply and the drug pusher 17 for conveying drug or nutriment to liver 27, connects medicine The drug catheter 18 of object pusher 17 sequentially passes through left side baffle 24 and right-hand apron 23 and connects oxygenation device by pipe joint 6 9 output ends into flow tube 13.The left cover 1 is connected through the hinge on left side baffle 24, and for closing leftward space 29.
As shown in fig. 7, being respectively arranged with controller 21 and oxygen cylinder 14 in the rear space 30, wherein the control Device 21 processed through the connection of the conducting wire of left side baffle 24 by being located at the accumulator 19 in leftward space 29, before the oxygen cylinder 14 End is located at the oxygenation device 9 in rightward space 28 through right-hand apron 23 by the connection of oxygen hose 15.14 traverse of oxygen cylinder is stuck in On one C-shaped grooves holder, C-shaped grooves holder is fixedly connected by screw with bottom plate 22.After closing rear space 30 Lid 3 is the cover board of L-type, and the bottom edge of the cover board of L-type is hinged by hinge and 22 posterior edge of bottom plate, is also provided on the rear cover 3 Heat emission hole 31 for cooling down to controller 21.
As shown in fig. 6, the upper cover 2 for sealing water bath 20 is connected through the hinge in the back side panel of water bath 20.Institute The structure for stating upper cover 2 is a plane cover, and upper surface is in same with left cover 1, right cover 4 and rear cover 3 after the closing of upper cover 2 Plane is used only for sealing water bath.The upper cover 1 can also be the structure type of a dished cover, after upper cover closing thereon Surface with respect to left cover 1, right cover 4 and rear cover 3 surface protrude one piece of rectangular or hemispherical dome structure, upper cover using saturating plastics, The materials such as metal or organic glass are made.
A kind of operation principle of portable liver room temperature save set of the present invention is:Liver 27 passes through an independent plastics Box or polybag etc. are stored in what waters kept apart in water bath 20, and blood is provided by diversion pipe 10 through peristaltic pump 11 dynamic Enter oxygenation device 9 after power, the oxygen in oxygen cylinder 14 enters oxygenation device 9 and blood oxygenation by oxygen hose 15.Oxygen closes Blood into flow tube 13 by flowing into liver artery afterwards, and drug pusher 17 pushes the drug of liver or nutriment passes through drug Connector 6 is mixed into into flow tube 13 and blood in liver body conduit 18 by the road.Blood passes through liver artery after liver It is connect with return duct 7, venous blood flows to filter 8 by return duct 7, and the bubble in blood is floating and impurity etc. is through filter 8 Filtering flows to peristaltic pump 11 into diversion pipe 10.Flow and flow control into flow tube are adjusted by flow electrically-controlled valve 25.Stream Amount electrically-controlled valve 25, the temperature of water bath 20 are controlled by controller, and accumulator 19 is powered controller.Finally, water The parameters such as bath cabinet temperature, velocity of blood flow, flow are output to display screen 5 by controller and show, the bile of hepatic secretion flows back into In bile container 26.
Schematically the present invention and embodiments thereof are described above, description is not limiting, institute in attached drawing The several embodiments of the only present invention shown, actual structure are also not limited thereto.If those skilled in the art by It is enlightened, without departing from the spirit of the invention, the structure, transmission and the installation that take other form and connection side Formula not inventively designs frame mode similar with the technical solution and embodiment, should all belong to the protection model of the present invention It encloses.

Claims (8)

1. a kind of portable liver room temperature save set includes that babinet is used to place liver with what is be arranged in babinet(27)'s Water bath(20), which is characterized in that it is respectively arranged in the babinet:Pass through return duct(7)Connect the liver(27)With In to liver(27)The filter that the venous blood of outflow is filtered(8), an input terminal passes through peristaltic pump(11)And water conservancy diversion Pipe(10)Connect filter(8)Output end, another input terminal passes through oxygen hose(15)Connect oxygen cylinder(14)For by oxygen Gas carries out the oxygenation device of oxygen conjunction with venous blood(9), the oxygenation device(9)Output by into flow tube(13)Exist with setting It is described into flow tube(13)On flow electrically-controlled valve(25)Connect liver(27), positioned at oxygenation device(9)Output end to flow Electrically-controlled valve(25)Input terminal between into flow tube(13)On also pass through a pipe joint(6)With with pipe joint(6)It is connected Drug catheter(18)Connection is for liver(27)Convey the drug pusher of drug or nutriment(17), the water-bath Case(20)It is inside additionally provided with and the liver(27)It is connected for receiving liver(27)The bile container of the bile secreted out of (26), be additionally provided in the babinet respectively with the peristaltic pump(11), flow electrically-controlled valve(25)And water bath(20)In The connected controller of heating device(21), and be used for controller(21)The accumulator of power supply is provided(19), the case It is provided on body front panel and the controller(21)It is connected for showing water bath(20)Temperature, velocity of blood flow, blood The display screen of flow parameter(5), the pipe joint(6)The magnet ring for being a triple valve or connecting for blood vessel is quickly right Connection device.
2. a kind of portable liver room temperature save set according to claim 1, which is characterized in that the babinet includes There is bottom plate(22), bottom plate is fixedly installed to by screw respectively(22)On right-hand apron(23)With left side baffle(24), described Right-hand apron(23)With left side baffle(24)By the bottom plate(22)Top is divided into rightward space(28), central space and a left side Side space(29), the front of the central space, which is set up separately, is equipped with water bath(20), the rear part of the central space constitutes rear side Space(30), wherein the rightward space(28), leftward space(29), water bath(20)And rear space(30)Upper difference It is corresponding to be provided with right cover(4), left cover(1), upper cover(2)And rear cover(3).
3. a kind of portable liver room temperature save set according to claim 2, which is characterized in that the right cover(4) Close to bottom plate(22)One is opened on the edge at place is easy to open right cover(4)The slot of U(32).
4. a kind of portable liver room temperature save set according to claim 2, which is characterized in that the rightward space (28)Inside it is provided with:By screw, it is bonded or is weldingly fixed on bottom plate(22)On fixation band(12), pass through fixed band(12) It is arranged in the bottom plate(22)On peristaltic pump(11), it is respectively fixedly connected in the right-hand apron(23)On oxygenation device (9)And filter(8), it is connected to filter(8), peristaltic pump(11)And oxygenation device(9)Between for conveying venous blood Diversion pipe(10)By being connected to the fixed band with welding, bonding or screw(12)On fixed chuck(12A)Positioning In the peristaltic pump(11)On, the right-hand apron(23)On also extended through oxygen cylinder(14)Front end, the oxygen cylinder (14)Oxygen discharge pass through oxygen hose(15)Connect oxygenation device(9)Oxygen input port, the filter(8)Pass through Through the right-hand apron(23)Return duct(7)Connection is located at water bath(20)Interior liver(27).
5. a kind of portable liver room temperature save set according to claim 2, which is characterized in that the leftward space (29)Inside it is provided with:It is fixed on bottom plate(22)On for controller(21)The accumulator of power supply is provided(19)With for liver It is dirty(27)Convey the drug pusher of drug or nutriment(17), connect drug pusher(17)Drug catheter(18)According to It is secondary to run through left side baffle(24)And right-hand apron(23)Pass through pipe joint(6)Connect oxygenation device(9)Output end into flow tube (13).
6. a kind of portable liver room temperature save set according to claim 2, which is characterized in that the rear space (30)Inside it is respectively arranged with controller(21)And oxygen cylinder(14), wherein the controller(21)By running through left side baffle (24)Conducting wire connection be located at leftward space(29)Interior accumulator(19), the oxygen cylinder(14)Front end run through right-hand apron (23)Pass through oxygen hose(15)Connection is located at rightward space(28)Interior oxygenation device(9).
7. a kind of portable liver room temperature save set according to claim 2, which is characterized in that for sealing water bath (20)Upper cover(2)It is connected through the hinge in water bath(20)Back side panel on, for closing rightward space(28)Right cover(4) It is connected through the hinge in right-hand apron(23)On, for closing leftward space(29)Left cover(1)It is connected through the hinge in left side Baffle(24)On.
8. a kind of portable liver room temperature save set according to claim 4, which is characterized in that the rear cover(3) Bottom edge for the cover board of L-type, the cover board of L-type passes through hinge and bottom plate(22)Posterior edge is hinged, the rear cover(3)On be also provided with For to controller(21)The heat emission hole of cooling(31).
CN201510540702.3A 2015-08-28 2015-08-28 A kind of portable liver room temperature save set Expired - Fee Related CN105165801B (en)

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CN106508890A (en) * 2016-10-28 2017-03-22 中山大学附属第医院 Multiple organ storage device
RU172275U1 (en) * 2016-12-29 2017-07-03 Федеральное государственное автономное научное учреждение "Центральный научно-исследовательский и опытно-конструкторский институт робототехники и технической кибернетики" (ЦНИИ РТК) Automated device for normothermic perfusion of an isolated donor liver

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US4473637A (en) * 1982-11-10 1984-09-25 Guibert, Colman & Associates System for processing an organ preparatory to transplant
CN1251586C (en) * 2003-11-20 2006-04-19 鞠烽炽 Portable preserving device for liver external perfusing
CN202232703U (en) * 2011-08-19 2012-05-30 天津市第一中心医院 Constant-temperature perfusion system for in-vitro liver
ES2388223B1 (en) * 2012-06-29 2013-09-02 Grifols Sa Device for perfusion of a liver graft
CN104430302B (en) * 2014-12-04 2016-05-18 宋涂润 For preserving the normal temperature filling system of human organ

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