CN105165801A - Portable liver normal-temperature storage device - Google Patents
Portable liver normal-temperature storage device Download PDFInfo
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- CN105165801A CN105165801A CN201510540702.3A CN201510540702A CN105165801A CN 105165801 A CN105165801 A CN 105165801A CN 201510540702 A CN201510540702 A CN 201510540702A CN 105165801 A CN105165801 A CN 105165801A
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Abstract
The invention provides a portable liver normal-temperature storage device. The device comprises a water-bath case which is used for accommodating a liver and is arranged in a tank body, wherein a filter connected with the liver by virtue of a return pipe, an oxygenation device, a controller and a storage battery which is used for supplying power to the controller are respectively arranged in the tank body; one input end of the oxygenation device is connected with the output end of the filter by virtue of a peristaltic pump and a honeycomb duct, the other input end of the oxygenation device is connected with an oxygen cylinder by virtue of an oxygen pipe, and the output of the oxygenation device is connected with the liver by virtue of an inflow pipe and the flow electric control valve which is arranged on the inflow pipe; the inflow pipe between the output end of the oxygenation device and the input end of the electric controlled valve is connected with a drug propeller by virtue of a pipeline connector and a drug conduit which is connected with the pipe connector; a bile container connected with the liver is arranged in the water-bath tank; the controller which is respectively connected with the peristaltic pump, the flow electric controlled valve and a heat device in the water-bath case and the storage battery are arranged in the tank body. The portable liver normal-temperature storage device is simple in structure and convenient to operate, and can be used for storing an in-vitro liver for a long time, even repairing the liver.
Description
Technical field
The present invention relates to a kind of liver normal temperature save set.Particularly relate to a kind of portable liver normal temperature save set.
Background technology
Since professor ThomasStarzl in 1963 is successfully completed the 1st routine Clinical Liver Transplantation, Technology of Liver Transplantation in China development rapidly, becomes the Main Means for the treatment of End-stage liver disease.The current whole world is increasingly serious for liver shortage situation, and this problem is particularly outstanding in China, and China about has 1,500,000 needs of patients organ transplants every year, and carries out organ transfer operation only 10,000 example left and right every year, and a large amount of patient is dead because of donor organ shortage.Along with improving constantly of Chinese society civilization degree, the donor organ quantity in Newgate saint source falls sharply, heart death contributes (donationaftercardiacdeath, DCD) become China's organ transplant donor main source, become the main path solving China's donor organ critical shortage.According to Chinese visible human organ donation center statistics, by 03 01st, 2015 registered organ donation volunteer 35290 people, 3188 examples successfully contributed by witness, given treatment to organ failure patient 8866.But China 13.4 hundred million All population capacities, far below World Developed Countries level, is still well worth doing relatively.
At present, a difficult problem for serious puzzlement China DCD organ donation is that DCD donor organ is second-rate, and the appraisal procedure of the science of shortage, not only has a strong impact on patient's prognosis, and causes practical efficiency very low.Not only suffer Low perfusion, the Warm ischemia injury of long period for liver, and experience Cryopreservation Injury, cause liver transplantation in world wide formerly to send out idle, delayed graft function incidence increases gradually.The simple Cord blood technology of UW liquid that the eighties in last century occurs once was regarded as the milestone of Clinical Liver Transplantation development, but UW Cord blood technology itself cannot precise evaluation for the vigor state of liver, also low temperature injury will be experienced, more cannot carry out injury repair, cannot meet the ever-increasing clinical demand of the Marginal donor livers such as DCD at present.
The novel mechanical Perfusion preservation technology of the simple Cord blood of UW liquid as an alternative, different according to the holding temperature of filling system, hypothermic machine perfusion (hypothermicmachineperfusion can be divided into, and normal temperature machine perfusion (normothermicmachineperfusion, NMP) HMP).HMP is conducive to the thorough lavation of intraorganic blood, is conducive to removing or dilution metabolic waste, and constantly provide the energy required for organ metabolism, significantly can reduce the incidence that graft function postpones, its effect is better than simple Cord blood simultaneously.HMP technique functions starts from the sixties, and period lies on the table due to reasons such as equipment and technology are complicated.At present along with increasingly serious for liver shortage situation, extend for the liver holding time, DCD increases for liver and Marginal donor liver, and HMP technology is in the success in kidney transplant field, and HMP technology becomes liver transfer operation study hotspot again.
But NMP is closer to physiological status, keeps normal metabolism and organize self-repairing capability.Have and continue to remain open for liver blood vessel bed; There is provided sufficient energy substrate and oxygen supply, the metabolic demand reduced under ensureing low-temperature condition; Timely removing or dilution metabolite and toxin; Effective removing is for advantages such as remaining microthrombus in liver.But there is the defects such as equipment is huge, technical sophistication in current NMP technology, limit the clinical practice of NMP, it is very important for therefore developing portable, easy equipment.
External NMP core technology also mainly concentrates on American-European minority developed country.Such as Canadian EVLP system, Britain Organ-OX system, U.S. Transmedic system, LifePort system, Dutch Organ-Assist system etc.China is badly in need of liver normal temperature and preserves and recovery technique, but due to such device technical difficulty large, domesticly there is no this series products, belong to blank field.2012 start, country starts 863 projects and " sets up the assessment of complete organ preservation and external reparation system and heart death donated organs, screening criteria " (problem number: 2012AA021001), this project is based on China's actual conditions, take into full account clinical demand, closely around the core improving Donor liver quality, by a large amount of zooperies, clinical discarded organ experiment, abandon the complicated huge defect of normal temperature machine perfusion technical equipment, successfully develop portable, simple and stable, intelligentized device.
Patent 201410384703.9 discloses the kidney being kept in existence device of a kind of low temperature or subnormal temperature, and it has started to consider to carry out organ preservation under subnormal temperature, improves the preservation quality of kidney, but not used for Liver Allograft Preservation.Patent 201410016261.2 discloses a kind of device and the store method of preserving isolated organ, the nutrient that its mode by machine perfusion and membrane oxygenation make isolated organ obtain continuing and oxygen supply, but, its structure is simple, the connection of each device, fixing and structural poor reliability, function is difficult to ensure.Patent 201510085562.5 discloses a kind of security protection enhancement mode organ hypothermia machine perfusion save set, and this device carries out organ preservation at low temperatures, realizes different fill-up mode by the various control signals of pump simultaneously.But this version is simple, each two pieces be fixedly connected with and realisation poor.Patent 201310723787.X discloses a kind of transplant organ protective bag, and this apparatus structure is simple, but this device also can only carry out organ preservation at low temperatures, cannot provide oxygen and blood circulation.
Summary of the invention
Technical problem to be solved by this invention is, provides the portable liver normal temperature save set that a kind of structure is simple, operability is good.
The technical solution adopted in the present invention is: a kind of portable liver normal temperature save set, include casing and be arranged on the water bath for placing liver in casing, be respectively arranged with in described casing: connect by return duct the filter that described liver filters for the venous blood flowed out liver, an input is connected the output of filter with mozzle by peristaltic pump, another input connects oxygen cylinder for oxygen and venous blood being carried out the oxygenation device of oxygenate by oxygen hose, the output of described oxygenation device is connected liver by influent stream pipe with the flow electrically-controlled valve be arranged on described influent stream pipe, oxygenation device output to flow electrically-controlled valve input between influent stream pipe on be also connected for the medicine pusher to liver delivering medicament or nutriment by a pipe joint and the drug catheter that is connected with pipe joint, the bile container be connected for receiving the bile that hepatic secretion goes out with described liver is also provided with in described water bath, also be provided with in described casing respectively with described peristaltic pump, the controller that flow electrically-controlled valve is connected with the heater in water bath, and for providing the accumulator of power supply to controller.
Described casing front panel is provided with to be connected with described controller for show water bath temperature, velocity of blood flow, blood flow parameter display screen.
Described pipe joint is a triple valve or the magnet ring fast junction apparatus connected for blood vessel.
Described casing includes base plate, right-hand apron on base plate and left side baffle plate is fixedly installed to respectively by screw, described right-hand apron and left side baffle plate are divided into rightward space, central space and leftward space by above described base plate, the forward part of described central space is provided with water bath, the rear section of described central space forms rear space, wherein, correspondingly respectively on described rightward space, leftward space, water bath and rear space right cover, left cover, upper cover and bonnet is provided with.
Described right cover opens the groove that is easy to open right cover U on the edge near base plate place.
Be provided with in described rightward space: pass through screw, bonding or be weldingly fixed on base plate fixed band, the peristaltic pump on described base plate is arranged on by fixed band, be fixedly connected on the oxygenation device on described right-hand apron and filter respectively, be connected to filter, the mozzle for delivery of intravenous blood between peristaltic pump and oxygenation device passes through with welding, bonding or the screw fixed chuck be connected on described fixed band is positioned on described peristaltic pump, described right-hand apron also runs through the front end having oxygen cylinder, the oxygen discharge of described oxygen cylinder connects the oxygen input port of oxygenation device by oxygen hose, described filter connects by the return duct running through described right-hand apron the liver being positioned at water bath.
Be provided with in described leftward space: be fixed on base plate for provide to controller power supply accumulator and for the medicine pusher to liver delivering medicament or nutriment, the drug catheter connecting medicine pusher runs through left side baffle plate and right-hand apron are connected oxygenation device output influent stream pipe by pipe joint successively.
Controller and oxygen cylinder is respectively arranged with in described rear space, wherein, described controller connects by the wire running through left side baffle plate the accumulator being positioned at leftward space, and the front end of described oxygen cylinder is run through right-hand apron and connected the oxygenation device being positioned at rightward space by oxygen hose.
Upper cover for sealing water bath is connected through the hinge at the back side panel of water bath, and the right cover for closed rightward space is connected through the hinge at right-hand apron, and the left cover for closed leftward space is connected through the hinge at left side baffle plate.
Described bonnet is the cover plate of L-type, the base of the cover plate of L-type by hinge and bottom rear edge hinged, described bonnet also has the louvre for lowering the temperature to controller.
One of the present invention portable liver normal temperature save set, has following beneficial effect:
1. liver normal temperature save set of the present invention, structure is simple, easy to operate, can preserve in vitro liver for a long time, even can repair liver.
2. liver normal temperature save set of the present invention, carries out blood flow by single pump and pressure regulates, and can ensure suitable blood flow supply in operation, by the supply of oxygen, medicine or nutriment, increases Liver Allograft Preservation time and repairing quality.
3. first adopt PLC automatic control system in the world: this patent pressure and flow number feed back to PLC; PLC is according to principles such as maximum pressure restriction, minimum flow guarantee, aeroembolism detection shutdown; automatic control centrifugal pump motor rotating speed, and control gate vein electronics pressure-reducing valve realizes automatically controlling.
4. liver normal temperature save set of the present invention, by the temperature of controller Based Intelligent Control water bath, can ensure that liver carries out preserving and repairing at normal temperatures, cause the infringement of liver under farthest preventing low temperature condition.
5. part NMP device (Liverassist) adopts inferior caval vein freely to pass back into open Chu Xuechi, and partial devices (OrganX) adopts inferior vena cava cannula, closes the closed circulation of blood bag.And our both device fusions advantage, not only airtight preservation blood circulation reduces infection risk and the non-steeped preservation of liver, and avoids vascular catheterization to damage.Adequate drainage system, dual adequate drainage on liver, under liver, the blood in unimpeded drainage blood pond, avoid the drainage of vena cave direct cannulation, shift in position or rotating speed strengthen the suction easily caused, and cause aeroembolism, even can realize splitting from operation liver in filling process.
6. this device adopts narrow body blood pond container, avoids the low increase return duct of lower vessel level to suck the risk of air, increases travelling performance.
Accompanying drawing explanation
Fig. 1 is the present invention's portable liver normal temperature save set overall structure schematic diagram;
Fig. 2 is the present invention's portable liver normal temperature save set principle schematic;
Fig. 3 is one of pipeline structure schematic diagram on the right side of the present invention's portable liver normal temperature save set;
Fig. 4 is pipeline structure schematic diagram two on the right side of the present invention's portable liver normal temperature save set;
Fig. 5 is the present invention's portable liver normal temperature save set left side structure schematic diagram;
Fig. 6 is the present invention's portable liver normal temperature save set upper structure schematic diagram;
Fig. 7 is the present invention's portable liver normal temperature save set rear structure schematic diagram.
Wherein:
1: left cover 2: upper cover
3: bonnet 4: right cover
5: display screen 6: pipe joint
7: return duct 8: filter
9: oxygenation device 10: mozzle
11: peristaltic pump 12: fixed band
13: influent stream pipe 14: oxygen cylinder
15: oxygen hose 16: fixed chuck
17: medicine pusher 18: drug catheter
19: accumulator 20: water bath
21: controller 22: base plate
23: right-hand apron 24: left side baffle plate
25: flow electrically-controlled valve 26: bile container
27: liver 28: rightward space
29: leftward space 30: rear space
31: louvre 32:U groove
Embodiment
Below in conjunction with embodiment and accompanying drawing, one of the present invention portable liver normal temperature save set is described in detail.
As shown in Figure 1 and Figure 2, one of the present invention portable liver normal temperature save set, include casing and be arranged on the water bath 20 for placing liver 27 in casing, liver 27 is by independently leaving in water bath 20 of isolating of plastic casing or plastic sack etc. and waters.Be respectively arranged with in described casing: connect by return duct 7 filter 8 that described liver 27 filters for the venous blood flowed out liver 27, an input is connected the output of filter 8 by peristaltic pump 11 and mozzle 10, another input connects oxygen cylinder 14 for oxygen and venous blood being carried out the oxygenation device 9 of oxygenate by oxygen hose 15, the output of described oxygenation device 9 is connected liver 27 by influent stream pipe 13 with the flow electrically-controlled valve 25 be arranged on described influent stream pipe 13, oxygenation device 9 output to flow electrically-controlled valve 25 input between influent stream pipe 13 on is also connected for the medicine pusher 17 to liver 27 delivering medicament or nutriment by a pipe joint 6 and the drug catheter 18 that is connected with pipe joint 6, described pipe joint 6 be a triple valve or for blood vessel connect magnet ring fast junction apparatus (as number of patent application for 201510382795.1 or number of patent application involutory mode of magnet ring disclosed in 201510382849.4).The bile container 26 be connected for receiving the oozy bile of liver 27 with described liver 27 is also provided with in described water bath 20, the controller 21 be connected with described peristaltic pump 11, flow electrically-controlled valve 25 and the heater in water bath 20 respectively is also provided with in described casing, and for providing the accumulator 19 of power supply to controller 21.Described casing front panel is provided with to be connected with described controller 21 for show water bath 20 temperature, velocity of blood flow, blood flow parameter display screen 5.
As shown in Figure 1, described casing includes base plate 22, right-hand apron 23 on base plate 22 and left side baffle plate 24 is fixedly installed to respectively by screw, described right-hand apron 23 and left side baffle plate 24 are divided into rightward space 28, central space and leftward space 29 by above described base plate 22, the forward part of described central space is provided with water bath 20, the rear section of described central space forms rear space 30, wherein, correspondingly respectively on described rightward space 28, leftward space 29, water bath 20 and rear space 30 right cover 4, left cover 1, upper cover 2 and bonnet 3 is provided with.Described right cover 4, left cover 1, upper cover 2 and bonnet 3 can be opened respectively, settle the device such as disposable apparatus or oxygen cylinder before easy to use.Described right cover 4 opens a U groove 32 on the edge near base plate 22 place, is easy to open right cover 4.
As Fig. 3, shown in Fig. 4, be provided with in described rightward space 28: pass through screw, bonding or be weldingly fixed on base plate 22 fixed band 12, the peristaltic pump 11 on described base plate 22 is arranged on by fixed band 12, be screwed respectively by rigid connecting contact pin and be connected to oxygenation device 9 on described right-hand apron 23 and filter 8, be connected to filter 8, the mozzle 10 for pumping blood between peristaltic pump 11 and oxygenation device 9 passes through with welding, bonding or the screw fixed chuck 12A be connected on described fixed band 12 is positioned on described peristaltic pump 11, fixed band 12 can use one or more depending on reality to the fixation degree of peristaltic pump 11.Described right-hand apron 23 also runs through the front end having oxygen cylinder 14, the oxygen discharge of described oxygen cylinder 14 connects the oxygen input port of oxygenation device 9 by oxygen hose 15, described filter 8 connects by the return duct 7 running through described right-hand apron 23 liver 27 being positioned at water bath 20.Described right cover 4 is connected through the hinge on right-hand apron 23, and for closed rightward space 28.
As shown in Figure 5, be provided with in described leftward space 29: be fixed by screws on base plate 22 for provide to controller 21 power supply accumulator 19 and for the medicine pusher 17 to liver 27 delivering medicament or nutriment, the drug catheter 18 connecting medicine pusher 17 runs through left side baffle plate 24 and right-hand apron 23 are connected oxygenation device 9 output influent stream pipe 13 by pipe joint 6 successively.Described left cover 1 is connected through the hinge on left side baffle plate 24, and for closed leftward space 29.
As shown in Figure 7, controller 21 and oxygen cylinder 14 is respectively arranged with in described rear space 30, wherein, described controller 21 connects by the wire running through left side baffle plate 24 accumulator 19 being positioned at leftward space 29, and the front end of described oxygen cylinder 14 is run through right-hand apron 23 and connected the oxygenation device 9 being positioned at rightward space 28 by oxygen hose 15.Oxygen cylinder 14 traverse is stuck on a C type groove support, and C type groove support is fixedly connected with base plate 22 by screw.Bonnet 3 for closed rear space 30 is the cover plate of L-type, the base of the cover plate of L-type by hinge and base plate 22 posterior edge hinged, described bonnet 3 also has the louvre 31 for lowering the temperature to controller 21.
As shown in Figure 6, the upper cover 2 for sealing water bath 20 is connected through the hinge at the back side panel of water bath 20.The structure of described upper cover 2 is plane covers, and after upper cover 2 is closed, upper surface and left cover 1, right cover 4 and bonnet 3 are in same plane, only for sealing water bath.Described upper cover 1 can also be the version of a dished cover, after upper cover is closed, its upper surface is relative to outstanding one piece of square or hemispherical dome structure in the surface of left cover 1, right cover 4 and bonnet 3, and upper cover utilizes the materials such as plastics, metal or lucite to make.
The operation principle of a kind of portable liver normal temperature save set of the present invention is: liver 27 by one independently plastic casing or plastic sack etc. and waters keep apart leave in water bath 20, blood enters oxygenation device 9 by mozzle 10 after peristaltic pump 11 provides power, and the oxygen in oxygen cylinder 14 enters oxygenation device 9 and blood oxygenation through oxygen hose 15.After oxygenate, blood flows into liver artery by influent stream pipe 13, medicine pusher 17 push the medicine of liver or nutriment by drug catheter 18 by the road joint 6 enter influent stream pipe 13 and be mixed in liver body with blood.Blood is connected with return duct 7 by liver artery after liver, and venous blood flows to filter 8 through return duct 7, and the floating and impurity of the bubble in blood etc. filter through filter 8 and enter mozzle 10 and flow to peristaltic pump 11.The flow of influent stream pipe and flow control are regulated by flow electrically-controlled valve 25.The temperature of flow electrically-controlled valve 25, water bath 20 is controlled by controller, and accumulator 19 pairs of controllers are powered.Finally, the parameter such as water bath temperature, velocity of blood flow, flow outputs to display screen 5 by controller and shows, and the bile of hepatic secretion is back in bile container 26.
Schematically above be described the present invention and embodiment thereof, this description does not have restricted, and the just several embodiment of the present invention shown in accompanying drawing, actual structure is also not limited thereto.If those skilled in the art enlightens by it; when not departing from the invention aim; adopt the structure of other form, transmission and installation and connected mode without the creationary design frame mode similar to this technical scheme and embodiment, all should protection scope of the present invention be belonged to.
Claims (10)
1. a portable liver normal temperature save set, include casing and be arranged on the water bath (20) for placing liver (27) in casing, it is characterized in that, be respectively arranged with in described casing: connect by return duct (7) filter (8) that described liver (27) filters for the venous blood flowed out liver (27), an input is connected the output of filter (8) with mozzle (10) by peristaltic pump (11), another input connects oxygen cylinder (14) for oxygen and venous blood being carried out the oxygenation device (9) of oxygenate by oxygen hose (15), the output of described oxygenation device (9) is connected liver (27) by influent stream pipe (13) with the flow electrically-controlled valve (25) be arranged on described influent stream pipe (13), influent stream pipe (13) between the input of the output to flow electrically-controlled valve (25) that are positioned at oxygenation device (9) is also connected by a pipe joint (6) and the drug catheter (18) connected with pipe joint (6) the medicine pusher (17) be used for liver (27) delivering medicament or nutriment, the bile container (26) be connected for receiving liver (27) oozy bile with described liver (27) is also provided with in described water bath (20), also be provided with in described casing respectively with described peristaltic pump (11), the controller (21) that flow electrically-controlled valve (25) is connected with the heater in water bath (20), and for providing the accumulator (19) of power supply to controller (21).
2. one according to claim 1 portable liver normal temperature save set, it is characterized in that, described casing front panel is provided with to be connected with described controller (21) for show water bath (20) temperature, velocity of blood flow, blood flow parameter display screen (5).
3. one according to claim 1 portable liver normal temperature save set, is characterized in that, described pipe joint (6) is a triple valve or the magnet ring fast junction apparatus connected for blood vessel.
4. one according to claim 1 portable liver normal temperature save set, it is characterized in that, described casing includes base plate (22), right-hand apron (23) on base plate (22) and left side baffle plate (24) is fixedly installed to respectively by screw, described base plate (22) top is divided into rightward space (28) by described right-hand apron (23) and left side baffle plate (24), central space and leftward space (29), the forward part of described central space is provided with water bath (20), the rear section of described central space forms rear space (30), wherein, described rightward space (28), leftward space (29), correspondingly respectively on water bath (20) and rear space (30) be provided with right cover (4), left cover (1), upper cover (2) and bonnet (3).
5. one according to claim 4 portable liver normal temperature save set, it is characterized in that, described right cover (4) opens the groove (32) that is easy to open right cover (4) U on the edge near base plate (22) place.
6. one according to claim 4 portable liver normal temperature save set, it is characterized in that, be provided with in described rightward space (28): pass through screw, bonding or be weldingly fixed on base plate (22) fixed band (12), the peristaltic pump (11) on described base plate (22) is arranged on by fixed band (12), be fixedly connected on the oxygenation device (9) on described right-hand apron (23) and filter (8) respectively, be connected to filter (8), the mozzle for delivery of intravenous blood (10) between peristaltic pump (11) and oxygenation device (9) passes through with welding, bonding or the screw fixed chuck (12A) be connected on described fixed band (12) is positioned on described peristaltic pump (11), described right-hand apron (23) also runs through the front end having oxygen cylinder (14), the oxygen discharge of described oxygen cylinder (14) connects the oxygen input port of oxygenation device (9) by oxygen hose (15), described filter (8) connects by the return duct (7) running through described right-hand apron (23) liver (27) being positioned at water bath (20).
7. one according to claim 4 portable liver normal temperature save set, it is characterized in that, be provided with in described leftward space (29): be fixed on base plate (22) for provide to controller (21) power supply accumulator (19) and for the medicine pusher (17) to liver (27) delivering medicament or nutriment, the drug catheter (18) connecting medicine pusher (17) runs through left side baffle plate (24) and right-hand apron (23) to be connected oxygenation device (9) output influent stream pipe (13) by pipe joint (6) successively.
8. one according to claim 4 portable liver normal temperature save set, it is characterized in that, controller (21) and oxygen cylinder (14) is respectively arranged with in described rear space (30), wherein, described controller (21) connects by the wire running through left side baffle plate (24) accumulator (19) being positioned at leftward space (29), and the front end of described oxygen cylinder (14) is run through right-hand apron (23) and connected the oxygenation device (9) being positioned at rightward space (28) by oxygen hose (15).
9. one according to claim 4 portable liver normal temperature save set, it is characterized in that, upper cover (2) for sealing water bath (20) is connected through the hinge at the back side panel of water bath (20), right cover (4) for closed rightward space (28) is connected through the hinge in right-hand apron (23), and the left cover (1) for closed leftward space (29) is connected through the hinge in left side baffle plate (24).
10. one according to claim 4 portable liver normal temperature save set, it is characterized in that, the cover plate that described bonnet (3) is L-type, the base of the cover plate of L-type by hinge and base plate (22) posterior edge hinged, described bonnet (3) also has the louvre (31) for lowering the temperature to controller (21).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510540702.3A CN105165801B (en) | 2015-08-28 | 2015-08-28 | A kind of portable liver room temperature save set |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510540702.3A CN105165801B (en) | 2015-08-28 | 2015-08-28 | A kind of portable liver room temperature save set |
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| CN105165801A true CN105165801A (en) | 2015-12-23 |
| CN105165801B CN105165801B (en) | 2018-08-14 |
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| CN201510540702.3A Expired - Fee Related CN105165801B (en) | 2015-08-28 | 2015-08-28 | A kind of portable liver room temperature save set |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106508890A (en) * | 2016-10-28 | 2017-03-22 | 中山大学附属第医院 | Multi-organ preservation device |
| RU172275U1 (en) * | 2016-12-29 | 2017-07-03 | Федеральное государственное автономное научное учреждение "Центральный научно-исследовательский и опытно-конструкторский институт робототехники и технической кибернетики" (ЦНИИ РТК) | Automated device for normothermic perfusion of an isolated donor liver |
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| CN105165801B (en) | 2018-08-14 |
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