JP3188476B2 - 両性イオン形トロバフロキサシン - Google Patents

両性イオン形トロバフロキサシン

Info

Publication number
JP3188476B2
JP3188476B2 JP50343697A JP50343697A JP3188476B2 JP 3188476 B2 JP3188476 B2 JP 3188476B2 JP 50343697 A JP50343697 A JP 50343697A JP 50343697 A JP50343697 A JP 50343697A JP 3188476 B2 JP3188476 B2 JP 3188476B2
Authority
JP
Japan
Prior art keywords
compound
formula
polymorph
hygroscopic
polar solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP50343697A
Other languages
English (en)
Japanese (ja)
Other versions
JPH10511692A (ja
Inventor
アレン，ダグラス・ジョン・メルドラム
ジョセフ，デーヴィッド・ブラニング
ノーリス，ティモシー
Original Assignee
ファイザー・インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ファイザー・インコーポレーテッド filed Critical ファイザー・インコーポレーテッド
Publication of JPH10511692A publication Critical patent/JPH10511692A/ja
Application granted granted Critical
Publication of JP3188476B2 publication Critical patent/JP3188476B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Physical Water Treatments (AREA)
  • Processing Of Solid Wastes (AREA)
JP50343697A 1995-08-29 1996-07-29 両性イオン形トロバフロキサシン Expired - Fee Related JP3188476B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US297595P 1995-08-29 1995-08-29
US60/002,975 1995-08-29
PCT/IB1996/000756 WO1997007800A1 (en) 1995-08-29 1996-07-29 Zwitterionic forms of trovafloxacin

Publications (2)

Publication Number Publication Date
JPH10511692A JPH10511692A (ja) 1998-11-10
JP3188476B2 true JP3188476B2 (ja) 2001-07-16

Family

ID=21703460

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50343697A Expired - Fee Related JP3188476B2 (ja) 1995-08-29 1996-07-29 両性イオン形トロバフロキサシン

Country Status (30)

Country Link
EP (1) EP0850060A1 (hu)
JP (1) JP3188476B2 (hu)
KR (1) KR100343909B1 (hu)
CN (1) CN1190889A (hu)
AP (1) AP636A (hu)
AR (1) AR003985A1 (hu)
AU (1) AU704115B2 (hu)
BR (1) BR9609998A (hu)
CA (1) CA2229786C (hu)
CO (1) CO4480739A1 (hu)
CZ (1) CZ56698A3 (hu)
DZ (1) DZ2087A1 (hu)
GT (1) GT199600072A (hu)
HR (1) HRP960395B1 (hu)
HU (1) HUP9900170A3 (hu)
IL (1) IL122651A (hu)
MA (1) MA23966A1 (hu)
MY (1) MY113874A (hu)
NO (1) NO309814B1 (hu)
NZ (1) NZ312199A (hu)
OA (1) OA10669A (hu)
PE (1) PE12598A1 (hu)
PL (1) PL325170A1 (hu)
RU (1) RU2144921C1 (hu)
SK (1) SK23898A3 (hu)
TN (1) TNSN96109A1 (hu)
TR (1) TR199800339T1 (hu)
WO (1) WO1997007800A1 (hu)
YU (1) YU48396A (hu)
ZA (1) ZA967282B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1998000106A (es) 1997-08-01 1999-01-08 Pfizer Prod Inc Composiciones parenterales de alatroflaxacino
US7019142B2 (en) 1998-01-16 2006-03-28 Pfizer Inc. Process for preparing naphthyridones and intermediates
PA8466701A1 (es) * 1998-01-21 2000-09-29 Pfizer Prod Inc Comprimido de mesilato de trovafloxacino
US6114531A (en) * 1998-07-28 2000-09-05 Pfizer Inc. Process for preparing quinolone and naphthyridone carboxylic acids
HN1999000141A (es) * 1998-09-03 2000-06-19 Pfizer Prod Inc Procedimiento para preparar sales de trovafloxacina de adicion de acidos.
US6239141B1 (en) * 1999-06-04 2001-05-29 Pfizer Inc. Trovafloxacin oral suspensions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids

Also Published As

Publication number Publication date
BR9609998A (pt) 1999-07-06
HUP9900170A3 (en) 1999-11-29
PE12598A1 (es) 1998-03-20
CA2229786A1 (en) 1997-03-06
SK23898A3 (en) 1999-05-07
MA23966A1 (fr) 1997-04-01
DZ2087A1 (fr) 2002-07-22
JPH10511692A (ja) 1998-11-10
MY113874A (en) 2002-06-29
RU2144921C1 (ru) 2000-01-27
NO980862L (no) 1998-02-27
NO980862D0 (no) 1998-02-27
PL325170A1 (en) 1998-07-06
TR199800339T1 (xx) 1998-06-22
NO309814B1 (no) 2001-04-02
GT199600072A (es) 1998-02-14
NZ312199A (en) 1999-06-29
CZ56698A3 (cs) 1999-02-17
CA2229786C (en) 2002-02-19
EP0850060A1 (en) 1998-07-01
MX9801664A (es) 1998-08-30
HRP960395B1 (en) 2001-12-31
AP636A (en) 1998-04-09
HRP960395A2 (en) 1998-06-30
KR100343909B1 (ko) 2003-04-10
ZA967282B (en) 1998-03-02
IL122651A0 (en) 1998-08-16
AR003985A1 (es) 1998-09-30
IL122651A (en) 2000-02-17
TNSN96109A1 (fr) 2005-03-15
AP9600853A0 (en) 1996-10-31
CO4480739A1 (es) 1997-07-09
KR19990044232A (ko) 1999-06-25
AU6367696A (en) 1997-03-19
OA10669A (en) 2000-11-06
YU48396A (sh) 1998-12-23
HUP9900170A2 (hu) 1999-05-28
AU704115B2 (en) 1999-04-15
CN1190889A (zh) 1998-08-19
WO1997007800A1 (en) 1997-03-06

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Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees