JP3034331B2 - Non-aqueous cosmetics - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a non-aqueous cosmetic containing a selenium compound as a compounding component. More specifically, an object of the present invention is to provide a non-aqueous cosmetic which is excellent in quality stability and free from discoloration, deterioration, and odor.

[0002]

2. Description of the Related Art Changes in the state of the skin are being clarified, including changes in the state of the epidermis and dermis, and even changes in the biochemistry of cells. The main cause of this change is
It is thought to be due to the peroxidation reaction of the living body, but not only these endogenous factors, but also the skin is in direct contact with the outside world, so extrinsic factors such as ultraviolet rays can also be the cause. Cheap.

[0003] Also, the sebum of the surface of the skin contains many unsaturated fatty acid such as a saved emissions as a substrate for lipid peroxidation,
Further, cosmetics and the like applied to the skin are also tissues where lipid peroxides are easily generated because they contain oils and fats.

[0004] The relationship between the skin and lipid peroxide has been reported in female melanosis of the face, melasma, atopic dermatitis and the like. Also, it is known that peroxidized squalene has a significant irritating effect on the skin, and the inflammatory response caused by this is accompanied by pigmentation.

[0005] Since lipid peroxide has an adverse effect on the skin as described above, reducing the amount of lipid peroxide is important not only for preventing aging of the skin but also for making the skin healthy, young and fresh. It is important from the point of maintaining.

[0006] Some cosmetics are susceptible to deterioration, for example, the cosmetics themselves produce lipid peroxide. Such deterioration is not preferable as a product because it not only has the above-mentioned adverse effects on the skin but also causes discoloration or odor.

Heretofore, in order to prevent deterioration of cosmetics, antioxidants such as dibutylhydroxytoluene (BH
T), delta tocopherol and the like have been incorporated into cosmetics.

[0008] Vitamin E and its derivatives, vitamin C, and the like have been used to suppress the production of lipid peroxide in the skin. Recently, enzymes such as superoxide dismutase and glutathione peroxidase have been used. There are not a few reports that they are effective (for a review, see the Cosmetic Society of Japan, Vol. 11, No. 1, 1987).

However, conventionally known vitamins and enzymes are very unstable, and thus lose their effect of suppressing the production of lipid peroxide over time when incorporated into cosmetics.
The main function of the antioxidant is to prevent itself from being oxidized and changed to another substance, thereby preventing the oxidation of other cosmetic ingredients. This is a so-called preventive action. However, these antioxidants do not have a function of reducing the peroxide once formed, or have only a weak force.

[0010] On the other hand, based on this viewpoint and the recognition that selenium is an essential component of the prosthetic group of glutathione peroxidase and that selenium has an effect of activating this enzyme, selenium-containing algae were converted to other algae. Skin regenerating cosmetics that are formulated in combination with components have been reported (Japanese Patent Application Laid-Open No. 63-63).
313708).

Further, a water-containing cosmetic which prevents skin damage caused by ultraviolet irradiation by blending a selenoamino acid has been patented in the United States (US Pat. Nos. 4,8).
No. 65,840).

[0012]

However, when formulated in cosmetics, a compound capable of suppressing the production of lipid peroxide and stably exhibiting the effect of decomposing and eliminating already generated peroxide is formulated. Such non-aqueous cosmetics are not known, and non-aqueous cosmetics having an excellent effect of preventing quality deterioration are desired.

[0013]

Means for Solving the Problems The present inventor has conducted intensive studies in view of such circumstances, and as a result, by adding a selenium compound to cosmetics, the amount of peroxide produced has been reduced, and it has been conventionally used. By using antioxidants together,
They have found that they can exert their effects on peroxide in terms of both prevention of formation and decomposition, and have completed the present invention.

That is, the present invention provides a selenium compound comprising a cosmetic
0.0005 to 3% by weight based on the whole and an antioxidant
It relates nonaqueous cosmetic characterized by containing
is there.

Hereinafter, the present invention will be described in detail. The non-aqueous cosmetic of the present invention is produced by blending a selenium compound with a conventional non-aqueous cosmetic.

The non-aqueous cosmetic of the present invention refers to a cosmetic containing no water or containing only a trace amount (0.5% by weight or less). For example, they include lipsticks, white powders and powdered powders, eyebrows and cheek cosmetics, oily or powder foundations, and the like.

<1>. Selenium compound used in the present invention The selenium compound used in the present invention is an organic selenium compound,
Any of the inorganic selenium compounds can be used.

Examples of the organic selenium compound include selenoamino acids such as selenomethionine, selenocysteine, and selenocystine, and salts thereof.

Examples of the inorganic selenium compound include selenates and selenites, for example, alkali metal selenates such as potassium selenite, alkali metal selenites such as sodium selenite , and selenium sulfide. Can be.

As the selenium compound to be used, not only an isolated selenium compound but also an extract of a plant or a microorganism containing the selenium compound can be used. Examples of such plants include carrots, rice, algae, and the like containing selenium at a high concentration.

The selenium compound is blended so as to be 0.0005 to 3% by weight based on the total amount of the cosmetic, and may be blended alone or in combination. Content ratio is 0.00
When the amount is less than 05%, the effect of improving the stability of the quality of the cosmetic is difficult to appear, and when the amount is more than 3% by weight, the dispersibility of the selenium compound is deteriorated, and the feel during use is poor.

<2>. Antioxidant used in the present invention By using an antioxidant together with the selenium compound in the non-aqueous cosmetic, the generation of peroxide itself can be suppressed.

Examples of such antioxidants include compounds such as butylhydroxyanisole and dibutylhydroxytoluene, vitamins such as tocopherol and γ-oryzanol, and vitamin-like agents.

[0024] These antioxidants are blended in an amount of 0.001 to 1% by weight based on the total amount of the cosmetic.

These may be used alone or in combination.

<3>. Method for Producing Non-Aqueous Cosmetic of the Present Invention The non-aqueous cosmetic of the present invention can be produced by a conventional method for producing a non-aqueous cosmetic. The selenium compound may be added at any stage of the production.

[0027]

EXAMPLES The present invention will be described in more detail with reference to Examples.

[0028]

Example 1 A lip color containing a selenium compound and an antioxidant was prepared and compared with that without. (Production method) The components in Table 1B were taken in a ball mill and mixed for 24 hours to form a paste. This paste was heated to 90 ° C., and the component A previously heated to 90 ° C. was added thereto, followed by stirring and homogenization. Just before pouring this into the mold, add the component of C,
The mixture was poured into a mold, cooled to 30 ° C., and taken out of the mold to obtain a product. In addition, each value of Table 1 shows weight%.

[0029]

[Table 1] Material Example 1 Comparative Example 1 Comparative Example 2 ───────────────────────── Microcrystalline wax 18.0 18.0 18.0 A Lanolin 10.0 10.0 10.0 Candelilla wax 3.0 3.0 3.0 Octyl tetanol 23.6 24.0 23.8 ───────────────────────── ──────────────────────────── Castor oil 30.0 30.0 30.0 Isopropyl myristate 4.0 4.0 4.0 B Titanium oxide 4.0 4.0 4.0 Red 201 3.5 3.5 3.5 Red No. 202 2.5 2.5 2.5 Yellow No. 4 Aluminum Lake 1.0 1.0 1.0 ────────────────────────────── C-butyl human peroxytoluene 0.2 − 0.2 Sodium selenite 0.2 − − ──────────────────── ─────────

(Evaluation Method) Five pieces of each of the three types of lip colors obtained above, a total of 15 pieces, were stored in a constant temperature room at 40 ° C. for 3 months, and then stored at 5 ° C. for the following items. The same lip color was compared with each other as a standard product.

Color, smell: sensory evaluation by visual observation or nose Feeling: stretching, sticking to skin when used
Comprehensively evaluate usability Color difference (ΔE ^* ): The lightness index L ^* and the chromaticness index a ^* and b ^* were measured using a Nippon Denshoku # 80 spectral colorimeter, and shown in JIS Z8105-2070. By the formula
E ^* was calculated. (Evaluation Criteria) All of the above-mentioned colors, smells, and feels were evaluated according to the following criteria.

◎: No change: Slight deterioration is observed Δ: Significant deterioration X: Extremely deteriorated (Results) The results are shown in Table 2 as an average value of five samples for each sample.

[0033]

[Table 2]

From these results, it was found that the lip color containing the selenium compound and the antioxidant was notably superior to those not containing the lip color .
It became clear that it had quality stability.

[0035]

Embodiment 3 Next, an embodiment in a face powder will be described. (Preparation method) The components of Table 3A
After mixing well at high speed for 1 minute, the mixture was ground using a hammer mill. This was again mixed with the component B at a low speed in a Henschel mixer for 10 minutes, and then pulverized with a hammer mill to obtain a product.

[0036]

[Table 3] 実 施 Raw material example 2 (%) Comparative example 3 (%) ────── ──────────────────── Paraben 0.2 0.2 Talc 75.75 76.75 Kaolin 4.8 4.8 A Titanium oxide 5.0 5.0 Bengala 1.0 1.0 Iron oxide yellow 2.5 2.5 Ultramarine 0.5 0.5 Spherical silica powder 4.0 4.0 ────────────────────────── Tertac tocopherol 0.05 0.05 Octyl decyl oleate 2.0 2.0 B Sweet almond oil 1.5 1.5 Quercerin triethylhexanoate 1.5 1.5 Fragrance 0.2 0.2 Selenium sulfide 1.0 − ──────────────────────────

(Evaluation) Each of the obtained face powders was stored at 50 ° C. for one month, and evaluated according to the same evaluation criteria as in Example 1. The results are shown in Table 4.

[0038]

[Table 4]

(Results) A face powder containing a selenium compound and an antioxidant (delta tocopherol)
Quality stability was better than that containing only antioxidant.

[0040]

Example 4 An oily foundation containing a selenium compound was prepared and compared with an oily foundation not containing the same. (Preparation method) Each component shown in Table 5A was mixed at a high speed for 2 minutes using a Henschel mixer, and then ground with a hammer mill.
This was heated to 80 ° C. in a melting pot, and the components of B were added and mixed, then cooled and filled in a container.

[0041]

[Table 5] 実 施 Raw material example 3 (%) Comparative example 4 (%) ───── ────────────────────── Talc 4.999 5.0 Kaolin 4.0 4.0 Titanium oxide 10.0 10.0 A Yellow iron oxide 4.0 4.0 Bengala 1.8 1.8 Ultramarine 0.7 0.7 Selenocystin 0.001 − ── ───────────────────────── ceresin 2.8 2.8 Vaseline 5.0 5.0 sorbitan sesquioleate 3.0 3.0 octyl decyl oleate 25.0 25.0 B beeswax 3.0 3.0 squalane 35.15 35.15 Tortatocopherol 0.05 0.05 Fragrance 0.3 0.3 Paraben 0.2 0.2 ───────────────────────────

(Evaluation) After the obtained oily foundation was stored at 40 ° C. for 3 months, it was evaluated according to the above evaluation criteria. The results are shown in Table 6.

[0043]

[Table 6]

(Results) The oil-based foundation containing the selenium compound and the antioxidant had better quality stability than that containing only the antioxidant.

[0045]

Example 5 A cake-like cheek color containing a selenium compound was produced and compared with that containing no selenium compound. (Preparation method) Each component in Table 7A was mixed well at high speed for 2 minutes using a Henschel mixer, and then pulverized by a hammer mill. Each component of B was added to the mixture, mixed again at a low speed for 10 minutes with a Henschel mixer, filled in a middle plate, and pressed with a press to obtain a product.

[0046]

[Table 7]

[0047] After the cake cheek color obtained (evaluation) were stored for 3 months at 40 ° C., evaluated by the evaluation criteria described above, the results in Table 8
It was shown to.

[0048]

[Table 8]

(Results) The cake-like cheek color containing the selenium compound and the antioxidant had better quality stability than that containing only the antioxidant.

[0050]

Example 6 A cake-like eye color containing a selenium compound was produced and compared with a product containing no selenium compound. (Preparation method) The components shown in Table 9A were mixed well at a high speed for 2 minutes using a Henschel mixer, and then pulverized by a hammer mill. Each component of B was added thereto and mixed again at a low speed at 80 ° C. for 10 minutes using a Henschel mixer. Further, this was pulverized by a hammer mill, filled in a middle plate, and pressed by a press to obtain a product.

[0051]

[Table 9] 実 施 Raw material example 5 (%) Comparative example 6 (%) ───── ────────────────────── Talc 38.98 38.99 Kaolin 5.0 5.0 Zinc stearate 6.5 6.5 A Ultramarine 15.0 15.0 Yellow iron oxide 4.0 4.0 Titanium dioxide 4.0 4.0 Titanium mica 8.0 8.0 Selenomethionine 0.01-─────────────────────────── Beeswax 15.0 15.0 Cetanol 0.80 0.80 B Liquid paraffin 2.5 2.5 Dimethyl human peroxytoluene 0.01 0.01 Fragrance 0.2 0.2 ───────────────────────────

(Evaluation) The obtained cake eye color was
After storing at 40 ° C. for 3 months, evaluation was performed according to the above-described evaluation criteria, and the results are shown in Table 10.

[0053]

[Table 10]

(Results) The cake-like eye color containing the selenium compound and the antioxidant had better quality stability than that containing only the antioxidant.

[0055]

According to the present invention, it is possible to provide a non-aqueous cosmetic composition which has little discoloration, discoloration and deterioration in use feeling even after long-term storage, and has excellent quality stability.

──────────────────────────────────────────────────続 き Continuation of the front page (51) Int.Cl. ⁷ Identification code FI A61K 7/027 A61K 7/027 (56) References JP-A-1-143822 (JP, A) JP-A-3-284613 (JP , A) (58) Fields investigated (Int. Cl. ⁷ , DB name) A61K 7/00 CA (STN)

Claims (2)

(57) [Claims] (1) A selenium compound is added in an amount of 0.0
005-3% by weight and an antioxidant
And non-aqueous cosmetics. 2. The content of the antioxidant is based on the total amount of the cosmetic.
2. The non-aqueous system according to claim 1, wherein the content is 0.001 to 1% by weight.
Cosmetics.