JP2771193B2 - Pest poison composition - Google Patents

Description

The present invention relates to a poison composition for insects such as cockroaches, ants, termites, bees, and fleas.

[Conventional technology]

Conventionally, as poisonous agents for cockroaches, for example, food-toxic insecticides using boric acid, organic phosphoric acid, and the like have been widely used in general households and the like because of their ease of use.

However, when a food-toxic insecticide is used, only the cockroaches fed with the food-toxic insecticide can kill insects, and the cockroaches that have not eaten at all or the cockroaches that consume a small amount of food do not die. There is. In particular, young cockroaches larvae consume less food, have a narrow range of action, and often live in places where it is difficult to install drugs, so many that do not eat any drugs remain, and cockroaches breed. Has become a major factor.

[Problems to be solved by the invention]

In view of the above-mentioned prior art, the present inventors have conducted intensive studies to develop cockroach poisons that can kill not only adult cockroaches but also young larvae. Given a cockroach poison composition comprising an active ingredient and a slow-acting insecticide as active ingredients, such adults gradually weakened and died over time, and larvae that came into contact with such adult dung became A completely new poison composition that is effective against both adults and larvae, not only being unable to lay eggs, but also being unable to lay eggs by being grown or inhibited by the insect growth inhibitors contained therein. Headings, and further such poison composition, ants, termites,
They have found for the first time that they are also effective against pests such as bees and fleas, and have completed the present invention.

[Means for solving the problem]

That is, the present invention relates to a pest poison composition comprising an insect growth inhibitor and a slow-acting insecticide as active ingredients.

[Operation and Examples]

The food poison composition for insect pests of the present invention is not only effective against cockroaches, but also includes an insect growth inhibitor (hereinafter referred to as IGR) in the feces of adults. The larvae that have contacted with are exhibiting an unprecedented completely epoch-making action, in which growth is suppressed and the animals cannot lay eggs and die.

That is, most of the cockroaches and the like fed the pest poison composition of the present invention die after several hours to several days. Scatter around. This strewn IGR
Imparts the above-mentioned physiological activity to adult and other larval cockroaches that inhabit there, and larvae such as cockroaches are inhibited from growing and from laying eggs. On the other hand, spawning of the surviving cockroaches and the like is suppressed, and as a result, the population density of the cockroaches and the like is reduced.

The IGR used in the present invention has a different action mechanism from conventional insecticides and has no immediate effect, but larvae such as cockroaches ingested or contacted with such an IGR through adult feces or the like are inhibited from growing. Even when it becomes an adult, it exhibits malformations such as atrophy of its wings, dies at the time of molting or emergence, and suppresses egg production. Furthermore, the spawning of adult adults that have taken or contacted IGR is also suppressed, and as a result, the growth of cockroaches and the like is suppressed.

By the way, in the present invention, even if only IGR is used, there is an effect of controlling cockroaches and the like, but it takes as long as three months or more to reduce the density of cockroaches and the like. In order to reduce the density of cockroaches and the like, combined use with insecticides is also essential.
In addition, when cockroaches and the like ingested IGR, they naturally have growth inhibitory activity against the ingested cockroaches and the like, but the ingested IGR was directly excreted without metabolism and excreted. It has a sufficiently effective physiological activity even in feces.

Examples of the IGR used in the present invention include juvenile hormones, juvenile hormone analogs, molting inhibitors and the like. Specific examples of such juvenile hormones, juvenile hormone analogs, molting inhibitors and the like include, for example, And optical isomers, geometric isomers, derivatives, analogs and the like thereof, and one or more of these are used as a mixture. If desired, only those components having higher activity can be selected and used from these compounds according to their potency and dosage form.

The compounding amount of the IGR is desirably appropriately selected depending on the desired effect of the obtained composition and the like, but is usually 0.01 to 20% (% by weight, hereinafter the same) based on the total amount of the compounding components, Preferably, it is set to 0.05 to 10%. When the amount is less than 0.01%, the effect of inhibiting the growth of cockroaches due to the incorporation of IGR tends to be insufficient, and when the amount is more than 20%, the repellency to eat tends to be strong. .

The slow-acting insecticide used with the IGR has a slow onset of efficacy, but when used in combination with the IGR,
Surprisingly, an appropriate insecticidal effect is exerted without the effect being manifested too slowly and without exhibiting the immediate effect like a rapid-acting insecticide. The term "slow-acting insecticide" as used in the claims means an insecticide that does not die until dung or a concentration-adjusted insecticide that does not die until dung.

As the slow-acting insecticide, for example, boric acid, borate, amidinohydrazone-based insecticides, organophosphorus-based, carbamate-based, pyrethroid-based, oxadiazole-based insecticides, etc. to reduce the compounding ratio, intake And insecticides adjusted so as to increase the time from death to death. One or more of these are used in combination.

Specific examples of the borate include, for example, sodium tetraborate (borax), sodium metaborate, sodium perborate, ammonium borate, potassium borate, magnesium borate, etc., and the amidinohydrazone-based Specific examples of the insecticide include, for example, tetrahydro-5,5-dimethyl-2 (IH) -pyrimidinoin ｛3
-[4- (trifluoromethyl) phenyl] -1- {2
-[4- (trifluoromethyl) phenyl] ethenyl}
-2-propenylidene hydrazone (hereinafter referred to as Amdro) and the like.

Examples of insecticides that can be used as slow-acting insecticides by adjusting the concentration to low concentrations include organophosphorus insecticides such as fenitrothion, trichlorfon, pyridafenthion, diazinon and fenthion; carbamate insecticides such as sevin and propoxer Resmethrin, d-T80-resmethrin, phenothrin, permethrin, phthalthrine, d-T80-phthalthrin,
Cyphenothrin, cypermethrin, fenvalerate,
Pyrethroid insecticides such as etofenprox, pralesulin, and fenfluthrin; and oxadiazole insecticides such as methoxadiazone.

The compounding amount of the slow-acting insecticide may be appropriately selected depending on the desired efficacy of the resulting composition, the type of insecticide, the type of cockroach to be treated, and the like. In the case of 5 to 70%, especially 10 to 50%, in the case of other insecticides 0.05 to 10%, especially 0.1 to 5
%.

When the amount of the boric acid or borate is less than 5%, the insecticidal effect tends not to be sufficiently exerted. Tends to decrease. When the content of the other insecticides is less than 0.05%, the insecticidal effect tends not to be sufficiently exerted, and when it exceeds 10%, the repellency to eating tends to be strong.

As the components below the IGR and the slow-acting insecticide, the composition of the present invention includes, for example, a feeding substance, an attractant component, an antioxidant, a preservative, an accidental food inhibitor, a coloring agent, and the like.

Examples of the feed substance include flour such as wheat flour, rice flour, rice bran, and corn flour; starches such as potato starch and corn starch; granulated sugar, maltose;
Examples include sugars such as arabinose, galactose, lactose, fructose, sorbitol, molasses and honey, and molasses and glycerin.

Examples of the attracting component include organic acids such as caprylic acid, caproic acid, capric acid, lauric acid, and oleic acid; higher alcohols such as octyl alcohol, dodecyl alcohol, and oleic alcohol; onion flavor, milk flavor, putter flavor, Food flavors such as strawberry flavor and coffee flavor.

Examples of the antioxidant include oxidizing agents such as 2,6-di-tert-butyl-4-methylphenol (hereinafter referred to as BHT) and 2,2'-methylenebis (4-methyl-6-t-butyl) phenol. Inhibitors.

Examples of the preservative include sombic acid, sombic acid salt, and paraoxybenzoic acid esters.

Examples of the foods for preventing accidental eating include pepper powder and pepper essence.

Examples of the colorant include Red No. 2, Red No. 3,
Red 102, Red 201, Yellow 4, Yellow 5, Blue 1
No. 2, Blue No. 2, carbon black and the like.

The compounding amount of the components other than the IGR and the slow-acting insecticide is I
Since it depends on the compounding amount of GR and the slow-acting insecticide, it cannot be unconditionally determined.
R and the rest of the slow-acting insecticide.

The pest poison composition of the present invention may be used as a powder as it is, or may be used as a tablet, or may be made into a paste form by adding water or edible oil. For the purpose of improvement, microcapsules using polyurethane, gelatin or the like or inclusion compounds using cyclodextrin may be used, and the present invention is not limited by the form of the composition.

Next, the pest poison composition of the present invention will be described in more detail based on Production Examples and Examples, but the present invention is not limited to only these Examples.

Production Example 1 Formula as IGR: 0.4 parts of 2- [1-methyl-2- (4-phenoxyphenoxy) ethoxy] pyridine (parts by weight, the same applies hereinafter), 15 parts of boric acid, 37.9 parts of flour, and 35 parts of granulated sugar
Parts, glycerin 10 parts, onion flavor 1.0 part, capsicum essence 0.5 part and carbon black 0.2 part were uniformly mixed to prepare a composition of the present invention, and a preparation prepared by tableting 10 g of this composition into a tablet having a diameter of 30 mm and a thickness of 12 mm was prepared. I got it.

Production Example 2 Formula as IGR: Propyl aldehyde oxime 0-2- (4
-Phenoxyphenoxy) ethyl ether 0.5 part, Amdro 1.5 part, potato starch 52.1 parts, granulated sugar 20
Parts, fructose 25 parts, milk flavor 0.5 parts, BHT0.
One part and 0.3 part of Red No. 102 were uniformly mixed to prepare a composition of the present invention, and 10 g of the composition was tabletted into a tablet having a diameter of 30 mm and a thickness of 14 mm.

Production Example 3 Ethyl (7S) (2E, 4E) -3,7,11-trimethyl-2,4-
Dodecadienoate (hereinafter referred to as IGR (7S) isomer)
1.0 part, fenitrothion 2.0 parts, corn starch 50.2
Parts, lactose 20 parts, sorbitol 20 parts, molasses 5 parts,
Caproic acid 1 part, BHT 0.2 part, Capsicum essence 0.3
And 0.3 parts of carbon black were uniformly mixed to prepare a composition of the present invention, and 10 g of the composition was tabletted into a tablet having a diameter of 30 mm and a thickness of 14 mm.

Production Example 4 Formula as IGR: Isopropyl (2E, 4E) -11-methoxy-
3,7,11-trimethyl-2,4-dodecadienoate 5.0 parts,
Trichlorfon 2.5 parts, flour 31.3 parts, potato starch 2
0 parts, granulated sugar 30 parts, arabinose 10 parts, butter flavor 0.5 parts, red pepper essence 0.2 parts and red
No. 102 uniformly mixed 0.5 part to prepare a composition of the present invention,
This 10 g was tableted into a tablet having a diameter of 30 mm and a thickness of 13 mm.

Production Example 5 Formula as IGR: 1- (4-chlorophenyl) -3- (2,6
-Difluorobenzoyl) urea 0.05 part, boric acid 25 parts,
20.95 parts of corn starch, 20 parts of granulated sugar, molasses 2
Parts, 2 parts of onion flavor and 30 parts of flour were uniformly mixed to prepare a composition of the present invention.
A tablet was obtained having a thickness of 14 mm and a thickness of 14 mm.

Production Example 6 Ethyl (7RS) (2E, 4E) -3,7,11-trimethyl-2,4
-2.0 parts of dodecadienoate, 2.0 parts of trichlorfon, 35.0 parts of flour, 20 parts of potato starch, 30 parts of granulated sugar,
Sorbitol (10 parts), milk flavor (0.2 parts), BHT (0.5 parts) and carbon black (0.3 parts) were uniformly mixed to prepare a composition of the present invention, and 10 g of the composition was tabletted into a tablet having a diameter of 30 mm and a thickness of 13 mm.

Production Example 7 Formula as IGR: 0.5 parts of 2- [1-methyl-2- (4-phenoxyphenoxy) ethoxy] pyridine represented by the formula:
0.5 parts, flour 43.5 parts, rice bran 10 parts, corn starch 20
Parts, granulated sugar 20 parts, molasses 5 parts and butter flavor 0.5 part to prepare a composition of the present invention by uniformly mixing,
This 10 g was tableted into a tablet having a diameter of 30 mm and a thickness of 15 mm.

Production Example 8 Formula as IGR: Propyl aldehyde oxime 0-2- (4
-Phenoxyphenoxy) ethyl ether 0.3 part, permethrin 0.3 part, flour 18.9 parts, potato starch 40.0
Parts, granulated sugar 40.0 parts and onion flavor 0.5
Parts were uniformly mixed to prepare a composition of the present invention.
Was tableted to a diameter of 30 mm and a thickness of 15 mm.

Production Example 9 IGR (7S) isomer 0.8 part, methoxadiazone 1.0 part, flour 36.4 parts, potato starch 30.0 parts, granulated sugar 30.0
Part, 0.5 part of onion flavor, 1.0 part of BHT, and 0.3 part of pepper essence were uniformly mixed to prepare a composition of the present invention, and 10 g of this composition was tabletted into a tablet having a diameter of 30 mm and a thickness of 14 mm.

Comparative Production Example 1 The same 2- [1-methyl-2- (4-phenoxyphenoxy) ethoxy] pyridine as IGR used in Production Example 1 0.4 part, flour 52.9 parts, granulated sugar 35 parts, glycerin 10 parts, onion A preparation was prepared by uniformly mixing 1.0 part of flavor, 0.5 part of pepper essence and 0.2 part of carbon black, and tableting 10 g of the resulting mixture into a tablet having a diameter of 30 mm and a thickness of 14 mm.

Comparative Production Example 2 The same propylaldehyde oxime-0-2- (4-phenoxyphenoxy) ethyl ether used in Production Example 2 as IGR 0.5 part, potato starch 53.6 parts, granulated sugar 20 parts, fructose 25 parts, milk flavor
0.5 part, 0.1 part of BHT and 0.3 part of Red No. 102 were uniformly mixed, and 10 g of the mixture was tabletted into a tablet having a diameter of 30 mm and a thickness of 15 mm.

Comparative Production Example 3 1.0 part of IGR (7S) isomer, 52.2 parts of corn starch, 20 parts of lactose, 20 parts of sorbitol, 5 parts of molasses, 1 part of caproic acid, 0.2 parts of BHT, 0.3 parts of pepper extract and 0.3 parts of carbon black Mix 10 g and mix
A tablet was obtained which was compressed to 30 mm and 15 mm in thickness.

Comparative Production Example 4 The same isopropyl (2E, 4E) -11-methoxy-3,7,11-trimethyl-2,4-IGR used in Production Example 4 as the IGR
5.0 parts of dodecadienoate, 33.8 parts of flour, 20 parts of potato starch, 30 parts of granulated sugar, 10 parts of arabinose, 0.5 part of butter flavor, 0.2 parts of pepper essence and 0.5 part of Red No. 102 are uniformly mixed and 10 g of diameter is obtained. 30mm,
There was obtained a tableted tablet having a thickness of 13 mm.

Comparative Production Example 5 Boric acid 25 parts, corn starch 20.95 parts, granulated sugar 2
0 parts, 2 parts of molasses, 2 parts of onion flavor and 30.05 parts of flour are uniformly mixed, and 10 g of the mixture is 30 mm in diameter and 12 parts in thickness.
A formulation compressed to mm was obtained.

Comparative Production Example 6 Trichlorfon 2.0 parts, flour 37.0 parts, potato starch 20 parts, granulated sugar 30 parts, sorbitol 10 parts, milk flavor 0.2 parts, BHT 0.5 parts and carbon black 0.3
The 10 g of the mixture was uniformly mixed to give a tableted tablet having a diameter of 30 mm and a thickness of 14 mm.

Comparative Production Example 7 0.5 part of a propoxer, 44 parts of flour, 10 parts of rice bran, 20 parts of corn starch, 20 parts of granulated sugar, 5 parts of molasses and 0.5 part of butter flavor were uniformly mixed, and 10 g of the resulting mixture was mixed with 10 g of a diameter of 30.
A formulation was tabletted to a thickness of 14 mm and a thickness of 14 mm.

Comparative Production Example 8 0.3 parts permethrin, 19.2 parts flour, 4 potato starch
0.0 parts, granulated sugar 40.0 parts and onion flavor
0.5 part was uniformly mixed to obtain a formulation obtained by tableting 10 g of the resulting mixture into a tablet having a diameter of 30 mm and a thickness of 14 mm.

Comparative Production Example 9 1.0 part of methoxadiazon, 37.2 parts of flour, 30.0 parts of potato starch, 30.0 parts of granulated sugar, onion flavor
0.5 part, 1.0 part of BHT and 0.3 part of chili pepper essence were mixed uniformly, and 10 g of the mixture was tabletted into a tablet having a diameter of 30 mm and a thickness of 14 mm.

Examples 1 to 9 and Comparative Examples 1 to 10 (Change in the population density of German cockroaches) 100 German cockroaches (80 larvae, 10 male adults, 10 female adults) were placed in a plastic container (445 x 356 x 230 mm). A shelter, water and 10 g of the preparation obtained in Production Examples 1 to 9 or Comparative Production Examples 1 to 9 were set. In Comparative Example 10, no preparation was used.

Five days later, the preparation was removed, and then fed with a normal feed for breeding, and the cockroach population density was examined every month. Table 1 shows the results.

According to the results shown in Table 1, it takes more than three months for the cockroach population to decrease with the IGR alone or the insecticide alone, and the decrease in the density is gradual. In the case of a single slow-acting insecticide, the density decreases after one month but increases rapidly after two months.

On the other hand, the preparations of Examples 1 to 9 of the present invention exhibited excellent synergistic effects of IGR and a slow-acting insecticide which were not observed in the single preparation of the comparative example, and showed a remarkable density suppressing effect even after 5 months. Is observed.

Production Example 10 As IGR, the same 2- [1-
[Methyl 2- (4-phenoxyphenoxy) ethoxy] pyridine, 0.4 part of granulated sugar and 59.6 parts of flour were prepared, and 3 g of the composition was tableted to a diameter of 10 mm and a thickness of 8 mm to obtain a test preparation.

Production Example 11 Formula: 0.5 parts of IGR represented by 40 parts of granulated sugar and flour
A composition consisting of 59.5 parts was prepared, and 3 g of the composition was tableted to a diameter of 10 mm and a thickness of 8 mm to obtain a test preparation.

Production Example 12 A composition consisting of 1.0 part of the IGR (7S) isomer, 40 parts of granulated sugar and 59.0 parts of flour was prepared, and 3 g of this composition was 10 mm in diameter.
The test preparation was obtained by tableting to a thickness of 8 mm.

Production Example 13 Formula: 5.0 parts IGR, 40 parts granulated sugar and flour
A composition consisting of 55.0 parts was prepared, and 3 g of the composition was tableted to a diameter of 10 mm and a thickness of 8 mm to obtain a test preparation.

Comparative Production Example 10 40 parts of granulated sugar and 60 parts of flour were mixed, and 3 g of this was mixed.
Was tableted to a diameter of 10 mm and a thickness of 8 mm to obtain a control preparation.

Examples 10 to 13 and Comparative Example 10 (Activity test of excreta (feces) of cockroaches) Twenty adult female German cockroaches were placed in a plastic container (φ
160mm x 60mm), shelter, water and Production Example 10
3 g of the test preparation obtained in 1313 or 3 g of the control preparation obtained in Comparative Production Example 10 were set.

Five days later, the test preparation and 20 female German cockroaches were removed. In the shelter and the plastic container with the excrement, 20 last-instar German cockroach larvae reared on a normal feed were reared until they became adults. Cockroaches became adults make normal virgin females or males paired with no drug treatment, check for production of F _1, 50
It cockroaches no production of F ₁ was determined the spawning inhibition rate as spawning inhibition worms in until the day after. In addition, the mortality at the time of emergence or before the formation of the ovule was determined. The results are shown in Table 2.

From the results shown in Table 2, the composition of the present invention showed
It can be seen that the excrement after ingestion has a sufficient growth inhibitory effect and egg-laying inhibitory effect.

Production Example 14 Formula as IGR: Isopropyl (2E, 4E) -11-methoxy-
17,7,11-trimethyl-2,4-dodecadienoate 17 parts,
20 parts of boric acid, 32.3 parts of flour, 30 parts of granulated sugar, 0.5 part of onion flavor and 0.2 part of Red No. 102 were uniformly mixed to prepare a composition of the present invention, and 10 g of the composition was punched to a diameter of 30 mm and a thickness of 12 mm. A tableted formulation was obtained.

Production Example 15 Formula as IGR: 1 part of 2- [1-methyl-2- (4-phenoxyphenoxy) ethoxy] pyridine, 5 parts of boric acid, 30 parts of granulated sugar, 10 parts of molasses, 23.5 parts of flour, 0.5 part of carbon black and 30 parts of water 5 g of the paste obtained by uniformly mixing the parts was placed in a plastic tray having a diameter of 30 mm and a height of 5 mm to obtain a preparation.

Production Example 16 0.5 part of IGR (7S) isomer, 10 parts of trichlorfon, 20 parts of potato starch, 23.9 parts of corn starch, 0.3 parts of pepper essence, 0.3 parts of carbon black, 30 parts of granulated sugar
Part, lactose 10 parts and glycerin 5 parts were uniformly mixed to prepare a composition of the present invention, and 10 g of the composition was tabletted into a tablet having a diameter of 30 mm and a thickness of 13 mm.

Examples 14 to 16 100 adult German cockroaches (50 males and 50 females) were placed in a plastic container (445 x 356 x 230 mm), and shelter, water and the preparation (10 g) obtained in Production Examples 14 to 16 were added to the container.
I set it. The number of deaths was investigated over time, and the cumulative mortality was calculated. Table 3 shows the results.

[Effect of the Invention] The pest poison composition of the present invention contains an IGR and a slow-acting pesticide as active ingredients, and is an adult such as a cockroach that has consumed such a pest poison composition. Can be killed after several hours to several days, and since such adults disperse the IGR in the habitat of the pest via feces and the like, the other pests are inhibited from growing or spawning by the IGR. In addition, larvae that have ingested feces or the like containing IGR are inhibited from growing and laying eggs, and thus have the effect of preventing reproduction.

──────────────────────────────────────────────────の Continued on the front page (51) Int.Cl. ⁶ identification code FI A01N 59/14 A01N 59/14 (58) Investigated field (Int.Cl. ⁶ , DB name) A01N 25/00-25/00 102 A01N 27/00-65/02 (Use AC00, BA06 of F-term theme code 4H011 and free words)

Claims (1)

(57) [Claims] 1. A pest poison composition comprising an insect growth inhibitor and a slow-acting insecticide as active ingredients.