JP2690215B2 - 無細胞抗百日咳菌ワクチン - Google Patents
無細胞抗百日咳菌ワクチンInfo
- Publication number
- JP2690215B2 JP2690215B2 JP3175819A JP17581991A JP2690215B2 JP 2690215 B2 JP2690215 B2 JP 2690215B2 JP 3175819 A JP3175819 A JP 3175819A JP 17581991 A JP17581991 A JP 17581991A JP 2690215 B2 JP2690215 B2 JP 2690215B2
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- vaccine
- pertussis
- replaced
- fha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
- A61K39/0018—Combination vaccines based on acellular diphtheria-tetanus-pertussis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT02071090A IT1248735B (it) | 1990-06-21 | 1990-06-21 | Vaccini acellulari contro la pertosse |
| IT20710A/90 | 1990-06-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH04368337A JPH04368337A (ja) | 1992-12-21 |
| JP2690215B2 true JP2690215B2 (ja) | 1997-12-10 |
Family
ID=11170908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3175819A Expired - Lifetime JP2690215B2 (ja) | 1990-06-21 | 1991-06-21 | 無細胞抗百日咳菌ワクチン |
Country Status (4)
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8412207D0 (en) | 1984-05-12 | 1984-06-20 | Wellcome Found | Antigenic preparations |
| GB8910570D0 (en) | 1989-05-08 | 1989-06-21 | Wellcome Found | Acellular vaccine |
| EP0484621A3 (en) * | 1990-07-11 | 1992-08-26 | American Cyanamid Company | Efficacious vaccines against bordetella pertussis comprising a combination of individually purified pertussis antigens |
| GB9513371D0 (en) | 1995-06-30 | 1995-09-06 | Biocine Spa | Immunogenic detoxified mutant toxins |
| GB9209118D0 (en) | 1992-04-28 | 1992-06-10 | Sb 120 Amsterdam Bv | Vaccine compositions |
| US5856122A (en) * | 1993-08-24 | 1999-01-05 | University Of Alberta | Modification of pertussis toxin |
| AU7788194A (en) | 1993-10-05 | 1995-05-01 | Medeva Holdings B.V. | Vaccine compositions |
| GB9326174D0 (en) * | 1993-12-22 | 1994-02-23 | Biocine Sclavo | Mucosal adjuvant |
| JP5148577B2 (ja) * | 1993-12-22 | 2013-02-20 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | 非毒性の粘膜アジュバント |
| WO1995029934A1 (en) * | 1994-04-28 | 1995-11-09 | Takeda Chemical Industries, Ltd. | Method of separating protective components of bordetella pertussis |
| US20030072774A1 (en) * | 1994-06-10 | 2003-04-17 | Diane M. Gajewczyk | Proteinaceous adjuvants |
| GB9500788D0 (en) * | 1995-01-16 | 1995-03-08 | Medeva Holdings Bv | Vaccine compositions |
| GB9622660D0 (en) | 1996-10-31 | 1997-01-08 | Biocine Spa | Immunogenic detoxified mutant toxin |
| US6818222B1 (en) | 1997-03-21 | 2004-11-16 | Chiron Corporation | Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants |
| GB9713156D0 (en) * | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
| RU2130778C1 (ru) * | 1998-07-31 | 1999-05-27 | Акционерное общество закрытого типа НПК "Комбиотех Лтд" | Комбинированная вакцина для иммунопрофилактики вирусного гепатита в, столбняка, дифтерии и коклюша |
| US7115730B1 (en) | 1999-04-27 | 2006-10-03 | Chiron Srl | Immunogenic detoxified mutant E. coli LT-A-toxin |
| GB9923060D0 (en) | 1999-09-29 | 1999-12-01 | Chiron Spa | Vaccine |
| US8574589B2 (en) | 2009-05-11 | 2013-11-05 | Novartis Ag | Antigen purification process for pertactin antigen |
| RU2014140521A (ru) * | 2012-03-08 | 2016-04-27 | Новартис Аг | Адъювантные составы бустерных вакцин |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6176422A (ja) * | 1984-09-22 | 1986-04-18 | Chemo Sero Therapeut Res Inst | 百日ぜきコンポ−ネントワクチンおよび百日ぜき・ジフテリア・破傷風混合ワクチンの製造方法 |
| IT1223334B (it) * | 1987-11-02 | 1990-09-19 | Sclavo Spa | Polipeptidi immunologicamente attivi con una tossicita' alterata utili per la preparazione di un vaccino antipertosse |
| AP8900132A0 (en) * | 1988-07-22 | 1991-01-14 | Smithkline Biolog | Bordetella pertussis vaccine |
| DK0396964T3 (da) * | 1989-04-28 | 1995-10-30 | Sclavo Spa | Pertussistoxin-mutanter, Bordetella-stammer, der er i stand til at producere sådanne mutanter, samt deres anvendelse til udvikling af antipertussis-vacciner |
| WO1991008294A1 (en) * | 1989-11-29 | 1991-06-13 | Smithkline Beecham Biologicals (S.A.) | Novel vaccine |
-
1990
- 1990-06-21 IT IT02071090A patent/IT1248735B/it active IP Right Grant
-
1991
- 1991-06-17 EP EP19910109883 patent/EP0462534A3/en not_active Withdrawn
- 1991-06-20 CA CA002045071A patent/CA2045071A1/en not_active Abandoned
- 1991-06-21 JP JP3175819A patent/JP2690215B2/ja not_active Expired - Lifetime
Non-Patent Citations (3)
| Title |
|---|
| Ｉｎｆｅｃｔｉｏｎ ａｎｄ Ｉｍｍｕｎｉｔｙ，Ｖｏｌ．５６，Ｎｏ．１２ （１９８８），Ｐ．３１８９−３１９５ |
| Ｉｎｆｅｃｔｉｏｎ ａｎｄ Ｉｍｍｕｎｉｔｙ，Ｖｏｌ．５８，Ｎｏ．５ （Ｍａｙ １９９０），Ｐ．１３０８−１３１５ |
| Ｓｃｉｅｎｃｅ，Ｖｏｌ．２４６ （１９８９） Ｐ．４９７−５００ |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0462534A2 (en) | 1991-12-27 |
| IT9020710A1 (it) | 1991-12-21 |
| CA2045071A1 (en) | 1991-12-22 |
| JPH04368337A (ja) | 1992-12-21 |
| IT9020710A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-06-21 |
| IT1248735B (it) | 1995-01-26 |
| EP0462534A3 (en) | 1992-12-02 |
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| Date | Code | Title | Description |
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| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 19960118 |