JP2523527B2 - ３′−アジド−ヌクレオシド類、それらの製造法、およびそれらからなる抗ビ−ルス剤 - Google Patents

３′−アジド−ヌクレオシド類、それらの製造法、およびそれらからなる抗ビ−ルス剤

Info

Publication number
JP2523527B2
JP2523527B2 JP61217871A JP21787186A JP2523527B2 JP 2523527 B2 JP2523527 B2 JP 2523527B2 JP 61217871 A JP61217871 A JP 61217871A JP 21787186 A JP21787186 A JP 21787186A JP 2523527 B2 JP2523527 B2 JP 2523527B2
Authority
JP
Japan
Prior art keywords
azido
active ingredient
formula
group
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP61217871A
Other languages
English (en)
Japanese (ja)
Other versions
JPS62103100A (ja
Inventor
リツトスター ライドアウト ジヤネツト
ウオルター バリイ デビツド
ヌシノフ レールマン サンドラ
ヘイダー セント クレアー マーサ
アレン フアーマン フイリツプ
アンドリユー フリーマン ジヨージ
ポール ジムマーマン トーマス
ウオルバーグ ジエラルド
エム．デ ミランダ ポウロ
レイ シエイバー サミー
エドワード カーク ザ サード レオーネ
ヒラリイ キング ダニー
ハーロン クレモンズ リチヤード
ホワイト ジヨフレイ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/776,899 external-priority patent/US4724232A/en
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of JPS62103100A publication Critical patent/JPS62103100A/ja
Application granted granted Critical
Publication of JP2523527B2 publication Critical patent/JP2523527B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP61217871A 1985-09-17 1986-09-16 ３′−アジド−ヌクレオシド類、それらの製造法、およびそれらからなる抗ビ−ルス剤 Expired - Fee Related JP2523527B2 (ja)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US06/776,899 US4724232A (en) 1985-03-16 1985-09-17 Treatment of human viral infections
US776899 1985-09-17
GB8523878 1985-09-27
GB8603447 1986-02-12
GB8603719 1986-02-14
GB8608272 1986-04-04
US8608272 1986-06-23
US8603719 1986-06-23
US8603447 1986-06-23
US8523878 1986-06-23
US877284 1986-06-23
GB8615322 1986-06-23
US877796 1986-06-23
US8615322 1986-06-23

Publications (2)

Publication Number Publication Date
JPS62103100A JPS62103100A (ja) 1987-05-13
JP2523527B2 true JP2523527B2 (ja) 1996-08-14

Family

ID=25108682

Family Applications (1)

Application Number Title Priority Date Filing Date
JP61217871A Expired - Fee Related JP2523527B2 (ja) 1985-09-17 1986-09-16 ３′−アジド−ヌクレオシド類、それらの製造法、およびそれらからなる抗ビ−ルス剤

Country Status (3)

Country Link
JP (1) JP2523527B2 (de)
DD (2) DD251984A5 (de)
ZA (1) ZA867013B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916122A (en) * 1987-01-28 1990-04-10 University Of Georgia Research Foundation, Inc. 3'-Azido-2',3'-dideoxyuridine anti-retroviral composition
DE3739366A1 (de) * 1987-04-10 1988-10-27 Boehringer Mannheim Gmbh Desaza-purin-nucleosid-derivate, verfahren zu deren herstellung sowie deren verwendung bei der nucleinsaeure-sequenzierung sowie als antivirale mittel
GB8800276D0 (en) * 1988-01-07 1988-02-10 Univ Liverpool Medical treatment
JPH02255696A (ja) * 1989-03-28 1990-10-16 Sanyo Kokusaku Pulp Co Ltd ３’―アジド―２’、３’―ジデオキシ―４―チオピリミジンヌクレオシド誘導体、その製法およびそれを用いた抗ウイルス剤
WO1997006179A1 (fr) * 1995-08-04 1997-02-20 Kobayashi Perfumery Co., Ltd. Procede permettant de produire des derives d'azidonucleoside
EP1937825B1 (de) 2005-09-26 2016-12-21 Gilead Pharmasset LLC Modifizierte 4'-nukleoside als antivirusmittel
DE102006037786A1 (de) 2006-08-11 2008-03-20 Resprotect Gmbh Nukleoside, diese enthaltendes Arzneimittel und deren Verwendung

Also Published As

Publication number Publication date
ZA867013B (en) 1988-04-27
JPS62103100A (ja) 1987-05-13
DD251984A5 (de) 1987-12-02
DD262802A5 (de) 1988-12-14

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Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees