JP2026012402A5 - - Google Patents

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Publication number
JP2026012402A5
JP2026012402A5 JP2025185622A JP2025185622A JP2026012402A5 JP 2026012402 A5 JP2026012402 A5 JP 2026012402A5 JP 2025185622 A JP2025185622 A JP 2025185622A JP 2025185622 A JP2025185622 A JP 2025185622A JP 2026012402 A5 JP2026012402 A5 JP 2026012402A5
Authority
JP
Japan
Prior art keywords
lnp
nucleic acid
mol
tissue
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025185622A
Other languages
English (en)
Japanese (ja)
Other versions
JP2026012402A (ja
Filing date
Publication date
Priority claimed from JP2022523031A external-priority patent/JP2022552009A/ja
Application filed filed Critical
Publication of JP2026012402A publication Critical patent/JP2026012402A/ja
Publication of JP2026012402A5 publication Critical patent/JP2026012402A5/ja
Pending legal-status Critical Current

Links

JP2025185622A 2019-10-18 2025-11-04 薬物送達のための脂質及び脂質ナノ粒子製剤 Pending JP2026012402A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962923258P 2019-10-18 2019-10-18
US62/923,258 2019-10-18
JP2022523031A JP2022552009A (ja) 2019-10-18 2020-10-19 薬物送達のための脂質及び脂質ナノ粒子製剤
PCT/US2020/056252 WO2021077066A1 (en) 2019-10-18 2020-10-19 Lipid and lipid nanoparticle formulation for drug delivery

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022523031A Division JP2022552009A (ja) 2019-10-18 2020-10-19 薬物送達のための脂質及び脂質ナノ粒子製剤

Publications (2)

Publication Number Publication Date
JP2026012402A JP2026012402A (ja) 2026-01-23
JP2026012402A5 true JP2026012402A5 (https=) 2026-01-30

Family

ID=75538682

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022523031A Pending JP2022552009A (ja) 2019-10-18 2020-10-19 薬物送達のための脂質及び脂質ナノ粒子製剤
JP2025185622A Pending JP2026012402A (ja) 2019-10-18 2025-11-04 薬物送達のための脂質及び脂質ナノ粒子製剤

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2022523031A Pending JP2022552009A (ja) 2019-10-18 2020-10-19 薬物送達のための脂質及び脂質ナノ粒子製剤

Country Status (8)

Country Link
US (1) US20220396556A1 (https=)
EP (1) EP4045020A4 (https=)
JP (2) JP2022552009A (https=)
KR (1) KR20220084365A (https=)
CN (1) CN114828836A (https=)
AU (1) AU2020368556A1 (https=)
CA (1) CA3155074A1 (https=)
WO (1) WO2021077066A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL303195A (en) 2020-11-25 2023-07-01 Akagera Medicines Inc Lipid nanoparticles for delivery of nucleic acids and related methods of use
CN113785975B (zh) * 2021-09-09 2023-08-29 天津医科大学 精胺、亚精胺脂质体在抗氧化、抗衰老中的应用
AR128959A1 (es) * 2022-04-04 2024-06-26 Spark Therapeutics Inc Mejora inmunológica del tratamiento del cáncer
US20230322689A1 (en) * 2022-04-08 2023-10-12 SunVax mRNA Therapeutics Inc. Ionizable lipid compounds and lipid nanoparticle compositions
EP4531819A2 (en) 2022-05-25 2025-04-09 Akagera Medicines, Inc. Lipid nanoparticles for delivery of nucleic acids and methods of use thereof
WO2024061354A1 (zh) * 2022-09-23 2024-03-28 北京键凯科技股份有限公司 一种抑制top1基因表达的干扰rna及其应用
AU2024231082A1 (en) * 2023-03-09 2025-10-16 Maxirna (Shanghai) Pharmaceutical Co., Ltd. Ionizable lipid molecule, preparation method therefor and use thereof
CN116082184B (zh) * 2023-04-12 2023-06-30 山东大学 基于环己二胺的可电离脂质、脂质纳米颗粒及其制备方法与应用
WO2025038494A1 (en) 2023-08-11 2025-02-20 Tune Therapeutics, Inc. Compositions, systems, and methods for lymphoid cell differentiation using targeted gene activation
WO2025059112A1 (en) * 2023-09-11 2025-03-20 The Trustees Of The University Of Pennsylvania Compositions and methods for t cell targeted extrahepatic delivery of therapeutic agents
CN117482066B (zh) * 2023-11-02 2024-08-13 深圳市易瑞生物技术股份有限公司 脂质组合物和用于脂质组合物的化合物
WO2025209467A1 (en) * 2024-04-01 2025-10-09 Longuide Biopharma Corporation Lipids and lipid nanoparticle formulations
WO2026003582A2 (en) 2024-06-27 2026-01-02 Axelyf ehf. Lipids and lipid nanoparticles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104119242B (zh) * 2008-10-09 2017-07-07 泰米拉制药公司 改善的氨基脂质和递送核酸的方法
ES2646630T3 (es) * 2008-11-07 2017-12-14 Massachusetts Institute Of Technology Lipidoides aminoalcohólicos y usos de los mismos
US7635707B1 (en) * 2008-11-10 2009-12-22 Intermune, Inc. Pirfenidone treatment for patients with atypical liver function
WO2015011633A1 (en) * 2013-07-23 2015-01-29 Protiva Biotherapeutics, Inc. Compositions and methods for delivering messenger rna
WO2018081638A1 (en) * 2016-10-27 2018-05-03 The Trustees Of The University Of Pennsylvania Nucleoside-modified rna for inducing an adaptive immune response

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