JP2025524769A - ２，４，６－トリヨードフェノール誘導体の製造方法 - Google Patents

２，４，６－トリヨードフェノール誘導体の製造方法

Info

Publication number
JP2025524769A
JP2025524769A JP2024571340A JP2024571340A JP2025524769A JP 2025524769 A JP2025524769 A JP 2025524769A JP 2024571340 A JP2024571340 A JP 2024571340A JP 2024571340 A JP2024571340 A JP 2024571340A JP 2025524769 A JP2025524769 A JP 2025524769A
Authority
JP
Japan
Prior art keywords
hydroxy
methyl
methylene
bis
phenylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024571340A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025524769A5 (enExample
Inventor
ボッタ，マウロ
テイ，ロレンツォ
カルニアート，ファビオ
バラニャイ，ジョルト
ボッカロン，マリアンジェラ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Imaging SpA
Original Assignee
Bracco Imaging SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging SpA filed Critical Bracco Imaging SpA
Publication of JP2025524769A publication Critical patent/JP2025524769A/ja
Publication of JP2025524769A5 publication Critical patent/JP2025524769A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2024571340A 2022-07-28 2023-07-28 ２，４，６－トリヨードフェノール誘導体の製造方法 Pending JP2025524769A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22187403.5 2022-07-28
EP22187403 2022-07-28
PCT/EP2023/071027 WO2024023314A1 (en) 2022-07-28 2023-07-28 1,4-bis-(2-hydroxy-benzyl)-1,4,7-triazacyclononane derivatives and similar compounds as ligands in iron(iii) complexes for use as mri contrast agents

Publications (2)

Publication Number Publication Date
JP2025524769A true JP2025524769A (ja) 2025-08-01
JP2025524769A5 JP2025524769A5 (enExample) 2026-01-30

Family

ID=82780974

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024571340A Pending JP2025524769A (ja) 2022-07-28 2023-07-28 ２，４，６－トリヨードフェノール誘導体の製造方法

Country Status (10)

Country Link
US (1) US12358880B2 (enExample)
EP (1) EP4561995B1 (enExample)
JP (1) JP2025524769A (enExample)
KR (1) KR20250040575A (enExample)
CN (1) CN119343336A (enExample)
AU (1) AU2023313342A1 (enExample)
CA (1) CA3252691A1 (enExample)
IL (1) IL317339A (enExample)
MX (1) MX2024015341A (enExample)
WO (1) WO2024023314A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025163025A1 (en) 2024-01-31 2025-08-07 Bracco Imaging Spa Pyridophane macrocyclic ligands and fe(iii) complexes thereof
CN119499407B (zh) * 2024-11-25 2026-04-07 中国科学院精密测量科学与技术创新研究院 一种Fe基T7肽靶向脑胶质瘤小分子磁共振造影剂及其制备合成方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3624859A4 (en) 2017-05-19 2021-03-03 The Research Foundation for The State University of New York COMPOUNDS FOR USE AS IRON (III) MRT CONTRAST AGENTS
EP3880635B1 (en) 2018-11-12 2023-01-04 Bracco Imaging SPA Chelating aazta conjugate, complexes thereof and use

Also Published As

Publication number Publication date
IL317339A (en) 2025-01-01
AU2023313342A1 (en) 2024-12-19
EP4561995B1 (en) 2026-05-27
WO2024023314A1 (en) 2024-02-01
US20250163007A1 (en) 2025-05-22
EP4561995A1 (en) 2025-06-04
US12358880B2 (en) 2025-07-15
CA3252691A1 (en) 2024-02-01
EP4561995C0 (en) 2026-05-27
CN119343336A (zh) 2025-01-21
KR20250040575A (ko) 2025-03-24
MX2024015341A (es) 2025-02-10

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