JP2025515484A5 - - Google Patents
Info
- Publication number
- JP2025515484A5 JP2025515484A5 JP2024563541A JP2024563541A JP2025515484A5 JP 2025515484 A5 JP2025515484 A5 JP 2025515484A5 JP 2024563541 A JP2024563541 A JP 2024563541A JP 2024563541 A JP2024563541 A JP 2024563541A JP 2025515484 A5 JP2025515484 A5 JP 2025515484A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- optionally substituted
- cycloalkyl
- group
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263336183P | 2022-04-28 | 2022-04-28 | |
| US63/336,183 | 2022-04-28 | ||
| US202263389237P | 2022-07-14 | 2022-07-14 | |
| US63/389,237 | 2022-07-14 | ||
| US202363456342P | 2023-03-31 | 2023-03-31 | |
| US63/456,342 | 2023-03-31 | ||
| PCT/US2023/020268 WO2023212240A1 (en) | 2022-04-28 | 2023-04-27 | Compounds for inhibiting kif18a |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025515484A JP2025515484A (ja) | 2025-05-15 |
| JP2025515484A5 true JP2025515484A5 (enExample) | 2026-05-11 |
Family
ID=86604316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024563541A Pending JP2025515484A (ja) | 2022-04-28 | 2023-04-27 | Ｋｉｆ１８ａを阻害するための化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230382889A1 (enExample) |
| EP (1) | EP4514790A1 (enExample) |
| JP (1) | JP2025515484A (enExample) |
| KR (1) | KR20250021398A (enExample) |
| CN (1) | CN119451951A (enExample) |
| AU (1) | AU2023261964A1 (enExample) |
| CA (1) | CA3256989A1 (enExample) |
| IL (1) | IL316450A (enExample) |
| MX (1) | MX2024013215A (enExample) |
| TW (1) | TW202346288A (enExample) |
| WO (1) | WO2023212240A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20211475A1 (es) | 2018-12-20 | 2021-08-05 | Amgen Inc | Inhibidores de kif18a |
| WO2023028564A1 (en) | 2021-08-26 | 2023-03-02 | Volastra Therapeutics, Inc. | Spiro indoline inhibitors of kif18a |
| AU2023254325A1 (en) * | 2022-04-15 | 2024-10-17 | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company | Kif18a inhibitor and use thereof |
| WO2024039829A1 (en) | 2022-08-18 | 2024-02-22 | Accent Therapeutics, Inc. | Inhibitors of kif18a and uses thereof |
| WO2025020624A1 (zh) * | 2023-07-25 | 2025-01-30 | 捷思英达控股有限公司 | 一种苯环衍生物、其制备方法及其在医药上的应用 |
| WO2025036479A1 (zh) * | 2023-08-16 | 2025-02-20 | 上海湃隆生物科技有限公司 | 驱动蛋白kif18a抑制剂及其应用 |
| WO2025090640A1 (en) | 2023-10-23 | 2025-05-01 | Volastra Therapeutics, Inc. | Solid formulations and polymorphic forms of indoline inhibitors of kif18a |
| WO2025247067A1 (zh) * | 2024-05-29 | 2025-12-04 | 上海复星医药产业发展有限公司 | Kif18A抑制剂 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6334997B1 (en) | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| CN1087725C (zh) | 1994-03-25 | 2002-07-17 | 同位素技术有限公司 | 用氘代方法增强药物效果 |
| CA3123227A1 (en) * | 2018-12-20 | 2020-06-25 | Amgen Inc. | Heteroaryl amides useful as kif18a inhibitors |
| MX2021007157A (es) * | 2018-12-20 | 2021-08-16 | Amgen Inc | Heteroarilamidas utiles como inhibidores de kif18a. |
| US12540129B2 (en) * | 2019-08-02 | 2026-02-03 | Amgen Inc. | KIF18A inhibitors |
| CN114302880B (zh) * | 2019-08-02 | 2025-07-15 | 美国安进公司 | Kif18a抑制剂 |
| CA3224249A1 (en) * | 2021-06-25 | 2022-12-29 | Hangzhou Innogate Pharma Co., Ltd. | Compound as kif18a inhibitor |
-
2023
- 2023-04-27 JP JP2024563541A patent/JP2025515484A/ja active Pending
- 2023-04-27 IL IL316450A patent/IL316450A/en unknown
- 2023-04-27 TW TW112115805A patent/TW202346288A/zh unknown
- 2023-04-27 EP EP23726722.4A patent/EP4514790A1/en active Pending
- 2023-04-27 AU AU2023261964A patent/AU2023261964A1/en active Pending
- 2023-04-27 CN CN202380045162.4A patent/CN119451951A/zh active Pending
- 2023-04-27 CA CA3256989A patent/CA3256989A1/en active Pending
- 2023-04-27 WO PCT/US2023/020268 patent/WO2023212240A1/en not_active Ceased
- 2023-04-27 KR KR1020247039543A patent/KR20250021398A/ko active Pending
- 2023-04-27 US US18/140,533 patent/US20230382889A1/en active Pending
-
2024
- 2024-10-25 MX MX2024013215A patent/MX2024013215A/es unknown
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