JP2025511938A5 - - Google Patents

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Publication number
JP2025511938A5
JP2025511938A5 JP2024559576A JP2024559576A JP2025511938A5 JP 2025511938 A5 JP2025511938 A5 JP 2025511938A5 JP 2024559576 A JP2024559576 A JP 2024559576A JP 2024559576 A JP2024559576 A JP 2024559576A JP 2025511938 A5 JP2025511938 A5 JP 2025511938A5
Authority
JP
Japan
Prior art keywords
polynucleotide
polynucleotides
segment
template
stranded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024559576A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025511938A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2023/059142 external-priority patent/WO2023194537A1/en
Publication of JP2025511938A publication Critical patent/JP2025511938A/ja
Publication of JP2025511938A5 publication Critical patent/JP2025511938A5/ja
Pending legal-status Critical Current

Links

JP2024559576A 2022-04-08 2023-04-06 ポリヌクレオチド(オリゴヌクレオチドを含む)の作製のための新規方法 Pending JP2025511938A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263328912P 2022-04-08 2022-04-08
US63/328,912 2022-04-08
US202263432466P 2022-12-14 2022-12-14
US63/432,466 2022-12-14
PCT/EP2023/059142 WO2023194537A1 (en) 2022-04-08 2023-04-06 Novel processes for the production of polynucleotides including oligonucleotides

Publications (2)

Publication Number Publication Date
JP2025511938A JP2025511938A (ja) 2025-04-16
JP2025511938A5 true JP2025511938A5 (https=) 2026-04-14

Family

ID=85985237

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024559576A Pending JP2025511938A (ja) 2022-04-08 2023-04-06 ポリヌクレオチド(オリゴヌクレオチドを含む)の作製のための新規方法

Country Status (8)

Country Link
US (1) US20250223620A1 (https=)
EP (1) EP4504932A1 (https=)
JP (1) JP2025511938A (https=)
KR (1) KR20240169697A (https=)
CN (1) CN119013398A (https=)
IL (1) IL315519A (https=)
TW (1) TW202405168A (https=)
WO (1) WO2023194537A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202340468A (zh) 2022-01-10 2023-10-16 中國大陸商杭州浩博醫藥有限公司 B型肝炎病毒(hbv)表現之調節
CN118460651B (zh) * 2024-07-10 2025-03-18 凯莱英医药集团(天津)股份有限公司 制备Cemdisiran的方法
CN118460654B (zh) * 2024-07-10 2025-02-14 凯莱英医药集团(天津)股份有限公司 一种Givosiran的制备方法
CN118460653B (zh) * 2024-07-10 2024-09-24 凯莱英医药集团(天津)股份有限公司 一种治疗α1-抗胰蛋白酶缺乏症的siRNA的制备方法
CN119876080B (zh) * 2025-01-15 2025-11-07 北京擎科生物科技股份有限公司 一种kod dna聚合酶突变体及其生产方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6683173B2 (en) 1998-04-03 2004-01-27 Epoch Biosciences, Inc. Tm leveling methods
US6586586B1 (en) 2000-01-31 2003-07-01 Isis Pharmaceuticals, Inc. Purification of oligonucleotides
AU2001241939A1 (en) * 2000-02-28 2001-09-12 Maxygen, Inc. Single-stranded nucleic acid template-mediated recombination and nucleic acid fragment isolation
GB201115218D0 (en) 2011-09-02 2011-10-19 Glaxo Group Ltd Novel process
US8808989B1 (en) 2013-04-02 2014-08-19 Molecular Assemblies, Inc. Methods and apparatus for synthesizing nucleic acids
GB201502152D0 (en) 2015-02-10 2015-03-25 Nuclera Nucleics Ltd Novel use
GB201503534D0 (en) 2015-03-03 2015-04-15 Nuclera Nucleics Ltd Novel method
AU2016341309A1 (en) * 2015-10-22 2018-06-07 Modernatx, Inc. Cancer vaccines
EP3393525A4 (en) * 2015-12-21 2019-08-21 Gen9, Inc. METHODS AND COMPOSITIONS FOR ASSEMBLING NUCLEIC ACIDS
GB201612011D0 (en) 2016-07-11 2016-08-24 Glaxosmithkline Ip Dev Ltd Novel processes for the production of oligonucleotides
JP2020507312A (ja) * 2017-02-10 2020-03-12 ザイマージェン インコーポレイテッド 複数の宿主用の複数のdnaコンストラクトのアセンブリ及び編集のためのモジュラーユニバーサルプラスミド設計戦略
GB201721307D0 (en) 2017-12-19 2018-01-31 Glaxosmithkline Ip Dev Ltd Novel processes for the production of oligonucleotides

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