JP2025511108A - トロンボポエチン受容体フラグメントおよびそれらの使用 - Google Patents

トロンボポエチン受容体フラグメントおよびそれらの使用 Download PDF

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Publication number
JP2025511108A
JP2025511108A JP2024557888A JP2024557888A JP2025511108A JP 2025511108 A JP2025511108 A JP 2025511108A JP 2024557888 A JP2024557888 A JP 2024557888A JP 2024557888 A JP2024557888 A JP 2024557888A JP 2025511108 A JP2025511108 A JP 2025511108A
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JP
Japan
Prior art keywords
polypeptide
calr
amino acid
tpor
seq
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Pending
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JP2024557888A
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English (en)
Japanese (ja)
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JP2025511108A5 (https=
Inventor
コンスタンチネスク，ステファン
ネデレック，オードリー
パパドポウロス，ニコラス
Original Assignee
ウニベルシテ カソリーク デ ルーベン
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Application filed by ウニベルシテ カソリーク デ ルーベン filed Critical ウニベルシテ カソリーク デ ルーベン
Publication of JP2025511108A publication Critical patent/JP2025511108A/ja
Publication of JP2025511108A5 publication Critical patent/JP2025511108A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2024557888A 2022-04-01 2023-03-31 トロンボポエチン受容体フラグメントおよびそれらの使用 Pending JP2025511108A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22166302.4 2022-04-01
EP22166302 2022-04-01
PCT/EP2023/058572 WO2023187201A1 (en) 2022-04-01 2023-03-31 Thrombopoietin receptor fragments and uses thereof

Publications (2)

Publication Number Publication Date
JP2025511108A true JP2025511108A (ja) 2025-04-15
JP2025511108A5 JP2025511108A5 (https=) 2026-04-03

Family

ID=81580134

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024557888A Pending JP2025511108A (ja) 2022-04-01 2023-03-31 トロンボポエチン受容体フラグメントおよびそれらの使用

Country Status (6)

Country Link
US (1) US20250250320A1 (https=)
EP (1) EP4504770A1 (https=)
JP (1) JP2025511108A (https=)
AU (1) AU2023244526A1 (https=)
CA (1) CA3246911A1 (https=)
WO (1) WO2023187201A1 (https=)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1230368A2 (en) * 1999-11-18 2002-08-14 Schering Corporation Mammalian receptor proteins; related reagents and methods

Also Published As

Publication number Publication date
WO2023187201A1 (en) 2023-10-05
CA3246911A1 (en) 2023-10-05
AU2023244526A1 (en) 2024-10-17
EP4504770A1 (en) 2025-02-12
US20250250320A1 (en) 2025-08-07

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