JP2025507308A5 - - Google Patents
Info
- Publication number
- JP2025507308A5 JP2025507308A5 JP2024546251A JP2024546251A JP2025507308A5 JP 2025507308 A5 JP2025507308 A5 JP 2025507308A5 JP 2024546251 A JP2024546251 A JP 2024546251A JP 2024546251 A JP2024546251 A JP 2024546251A JP 2025507308 A5 JP2025507308 A5 JP 2025507308A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- compound
- acceptable form
- isotopic derivative
- structural formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2022/075427 | 2022-02-08 | ||
| PCT/CN2022/075427 WO2023150899A1 (en) | 2022-02-08 | 2022-02-08 | Conjugates of chemotherapy agents and tissue-binding small molecules, compositions and methods thereof |
| PCT/CN2023/074329 WO2023151513A1 (en) | 2022-02-08 | 2023-02-03 | Conjugates of chemotherapy agents and tissue-binding small molecules, compositions and methods thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025507308A JP2025507308A (ja) | 2025-03-18 |
| JP2025507308A5 true JP2025507308A5 (enExample) | 2026-02-09 |
Family
ID=87563330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024546251A Pending JP2025507308A (ja) | 2022-02-08 | 2023-02-03 | 化学療法剤および組織結合小分子のコンジュゲート、組成物、ならびにその方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250082657A1 (enExample) |
| EP (1) | EP4476226A1 (enExample) |
| JP (1) | JP2025507308A (enExample) |
| CN (1) | CN118946569A (enExample) |
| AU (1) | AU2023217770A1 (enExample) |
| CA (1) | CA3243247A1 (enExample) |
| IL (1) | IL314835A (enExample) |
| WO (2) | WO2023150899A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118515573B (zh) * | 2024-07-19 | 2024-09-27 | 浙江省产品质量安全科学研究院 | 一种稳定同位素标记的氘代奥拉氟化合物的合成方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6350756B1 (en) * | 2001-01-18 | 2002-02-26 | California Pacific Medical Center | Camptothecin derivatives |
| CN1982313B (zh) * | 2005-12-13 | 2010-12-01 | 深圳市天和医药科技开发有限公司 | 10位取代基上含多个有机羧酸基团的喜树碱化合物及其制法与组合物 |
| US20160095939A1 (en) * | 2014-10-07 | 2016-04-07 | Immunomedics, Inc. | Neoadjuvant use of antibody-drug conjugates |
| US9150585B2 (en) * | 2012-11-13 | 2015-10-06 | Fl Therapeutics Llc | Analogs of camptothecin |
| CN103848840A (zh) * | 2012-12-03 | 2014-06-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 喜树碱衍生物及其医药用途 |
| CN105315294B (zh) * | 2014-06-26 | 2018-05-01 | 王杭祥 | 7-乙基-10-羟基喜树碱药物前体及其制备方法和应用 |
| CN104447777B (zh) * | 2014-11-26 | 2016-09-14 | 浙江大学 | 一种辣椒碱-喜树碱类抗癌药物偶联物及其制备方法和应用 |
| CN106377528B (zh) * | 2016-08-19 | 2019-05-31 | 湖北医药学院 | 一种羟基喜树碱戊二酸单酯的药物组合物 |
| CN106588946B (zh) * | 2017-01-25 | 2019-01-22 | 郑州大学 | 10-羟基喜树碱衍生物、合成方法及其应用 |
| KR101990214B1 (ko) * | 2017-12-12 | 2019-06-17 | 고려대학교 산학협력단 | 표적 특이적 항암 약물전구체 |
| CN109675050A (zh) * | 2018-12-27 | 2019-04-26 | 浙江工业大学 | 以喜树碱为母核的类似物与非甾体抗炎药物的偶联物及其制备与应用 |
| CN110372766A (zh) * | 2019-06-21 | 2019-10-25 | 广州中医药大学(广州中医药研究院) | 喜树碱糖类衍生物及其制备方法与应用 |
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2022
- 2022-02-08 WO PCT/CN2022/075427 patent/WO2023150899A1/en not_active Ceased
-
2023
- 2023-02-03 US US18/727,076 patent/US20250082657A1/en active Pending
- 2023-02-03 IL IL314835A patent/IL314835A/en unknown
- 2023-02-03 CA CA3243247A patent/CA3243247A1/en active Pending
- 2023-02-03 AU AU2023217770A patent/AU2023217770A1/en active Pending
- 2023-02-03 EP EP23752293.3A patent/EP4476226A1/en active Pending
- 2023-02-03 WO PCT/CN2023/074329 patent/WO2023151513A1/en not_active Ceased
- 2023-02-03 JP JP2024546251A patent/JP2025507308A/ja active Pending
- 2023-02-03 CN CN202380029671.8A patent/CN118946569A/zh active Pending