JP2025506729A - チエノピロロトリアジン化合物、それらの調製及びそれらの治療的使用 - Google Patents
チエノピロロトリアジン化合物、それらの調製及びそれらの治療的使用 Download PDFInfo
- Publication number
- JP2025506729A JP2025506729A JP2024549135A JP2024549135A JP2025506729A JP 2025506729 A JP2025506729 A JP 2025506729A JP 2024549135 A JP2024549135 A JP 2024549135A JP 2024549135 A JP2024549135 A JP 2024549135A JP 2025506729 A JP2025506729 A JP 2025506729A
- Authority
- JP
- Japan
- Prior art keywords
- acetamide
- isopropyl
- pyrrolo
- oxothieno
- triazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22315036.8 | 2022-02-21 | ||
| EP22315036 | 2022-02-21 | ||
| PCT/EP2023/054138 WO2023156643A1 (en) | 2022-02-21 | 2023-02-20 | Thienopyrrolotriazine compounds, their preparation and their therapeutic use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025506729A true JP2025506729A (ja) | 2025-03-13 |
| JP2025506729A5 JP2025506729A5 (https=) | 2026-02-27 |
Family
ID=81326677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024549135A Pending JP2025506729A (ja) | 2022-02-21 | 2023-02-20 | チエノピロロトリアジン化合物、それらの調製及びそれらの治療的使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250129091A1 (https=) |
| EP (1) | EP4482841A1 (https=) |
| JP (1) | JP2025506729A (https=) |
| KR (1) | KR20240151767A (https=) |
| CN (1) | CN118843632A (https=) |
| AU (1) | AU2023222186A1 (https=) |
| CA (1) | CA3244475A1 (https=) |
| CO (1) | CO2024010803A2 (https=) |
| IL (1) | IL314781A (https=) |
| MX (1) | MX2024010216A (https=) |
| WO (1) | WO2023156643A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116375728B (zh) * | 2021-12-31 | 2025-06-10 | 成都赜灵生物医药科技有限公司 | 噻吩吡咯并三嗪酮类化合物及其用途 |
| WO2025153532A1 (en) | 2024-01-16 | 2025-07-24 | NodThera Limited | Nlrp3 inhibitors and glp-1 agonists combination therapies |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210038877A (ko) * | 2018-07-25 | 2021-04-08 | 노파르티스 아게 | Nlrp3 인플라마좀 억제제 |
| JP2023523418A (ja) * | 2020-04-23 | 2023-06-05 | ヤンセン ファーマシューティカ エヌ．ベー． | Ｎｌｒｐ３の阻害剤としての三環式化合物 |
-
2023
- 2023-02-20 JP JP2024549135A patent/JP2025506729A/ja active Pending
- 2023-02-20 IL IL314781A patent/IL314781A/en unknown
- 2023-02-20 CN CN202380021421.XA patent/CN118843632A/zh active Pending
- 2023-02-20 EP EP23705039.8A patent/EP4482841A1/en active Pending
- 2023-02-20 WO PCT/EP2023/054138 patent/WO2023156643A1/en not_active Ceased
- 2023-02-20 MX MX2024010216A patent/MX2024010216A/es unknown
- 2023-02-20 AU AU2023222186A patent/AU2023222186A1/en active Pending
- 2023-02-20 US US18/834,987 patent/US20250129091A1/en active Pending
- 2023-02-20 CA CA3244475A patent/CA3244475A1/en active Pending
- 2023-02-20 KR KR1020247027615A patent/KR20240151767A/ko active Pending
-
2024
- 2024-08-08 CO CONC2024/0010803A patent/CO2024010803A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL314781A (en) | 2024-10-01 |
| KR20240151767A (ko) | 2024-10-18 |
| US20250129091A1 (en) | 2025-04-24 |
| MX2024010216A (es) | 2024-09-02 |
| CO2024010803A2 (es) | 2024-08-20 |
| CN118843632A (zh) | 2024-10-25 |
| EP4482841A1 (en) | 2025-01-01 |
| CA3244475A1 (en) | 2023-08-24 |
| WO2023156643A1 (en) | 2023-08-24 |
| AU2023222186A1 (en) | 2024-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20260218 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20260218 |