JP2025505542A - 直接圧縮可能なマンニトール顆粒 - Google Patents

直接圧縮可能なマンニトール顆粒 Download PDF

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Publication number
JP2025505542A
JP2025505542A JP2024544993A JP2024544993A JP2025505542A JP 2025505542 A JP2025505542 A JP 2025505542A JP 2024544993 A JP2024544993 A JP 2024544993A JP 2024544993 A JP2024544993 A JP 2024544993A JP 2025505542 A JP2025505542 A JP 2025505542A
Authority
JP
Japan
Prior art keywords
mannitol
granules
less
microcrystalline
tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024544993A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025505542A5 (https=
Inventor
ボワ、バティスト
サロメ、アントワーヌ
ブケ、ファブリス
ルフェーヴル、フィリップ
ターリエ、ニコラス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roquette Freres SA
Original Assignee
Roquette Freres SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR2201119A external-priority patent/FR3132522B1/fr
Application filed by Roquette Freres SA filed Critical Roquette Freres SA
Publication of JP2025505542A publication Critical patent/JP2025505542A/ja
Publication of JP2025505542A5 publication Critical patent/JP2025505542A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2024544993A 2022-02-08 2023-02-08 直接圧縮可能なマンニトール顆粒 Pending JP2025505542A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR2201119A FR3132522B1 (fr) 2022-02-08 2022-02-08 Granules de mannitol directement comprimable
FR2201119 2022-02-08
FR2211326 2022-10-28
FR2211326 2022-10-28
PCT/EP2023/025057 WO2023151868A1 (fr) 2022-02-08 2023-02-08 Granules de mannitol directement comprimables

Publications (2)

Publication Number Publication Date
JP2025505542A true JP2025505542A (ja) 2025-02-28
JP2025505542A5 JP2025505542A5 (https=) 2025-05-21

Family

ID=85278534

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024544993A Pending JP2025505542A (ja) 2022-02-08 2023-02-08 直接圧縮可能なマンニトール顆粒

Country Status (8)

Country Link
US (1) US20250134816A1 (https=)
EP (1) EP4475821A1 (https=)
JP (1) JP2025505542A (https=)
KR (1) KR20240138086A (https=)
AU (1) AU2023217824A1 (https=)
CA (1) CA3251212A1 (https=)
MX (1) MX2024009496A (https=)
WO (1) WO2023151868A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1036291A (ja) * 1996-04-16 1998-02-10 Takeda Chem Ind Ltd Ｄ−マンニトールおよびその製造法
JP2004002290A (ja) * 2001-12-13 2004-01-08 Merck Patent Gmbh 直接圧縮用β−マンニトールの製造方法
JP2012525361A (ja) * 2009-04-30 2012-10-22 ロケット・フルーレ マンニトールと顆粒状デンプンの圧縮性自由流動共凝集体
JP2018520192A (ja) * 2015-07-17 2018-07-26 ロケット フレールＲｏｑｕｅｔｔｅ Ｆｒｅｒｅｓ 直接圧縮用マンニトール顆粒

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0914164B1 (pt) * 2008-06-20 2019-04-30 Merck Patent Gmbh Comistura para produção de comprimidos de desintegração rápida em um processo de formação de comprimido direto, seus usos, e formulações de comprimido

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1036291A (ja) * 1996-04-16 1998-02-10 Takeda Chem Ind Ltd Ｄ−マンニトールおよびその製造法
JP2004002290A (ja) * 2001-12-13 2004-01-08 Merck Patent Gmbh 直接圧縮用β−マンニトールの製造方法
JP2012525361A (ja) * 2009-04-30 2012-10-22 ロケット・フルーレ マンニトールと顆粒状デンプンの圧縮性自由流動共凝集体
JP2018520192A (ja) * 2015-07-17 2018-07-26 ロケット フレールＲｏｑｕｅｔｔｅ Ｆｒｅｒｅｓ 直接圧縮用マンニトール顆粒

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PHARMACEUTICS, vol. 12, 886, JPN6026010649, 2020, pages 1 - 14, ISSN: 0005818698 *

Also Published As

Publication number Publication date
EP4475821A1 (fr) 2024-12-18
WO2023151868A1 (fr) 2023-08-17
US20250134816A1 (en) 2025-05-01
MX2024009496A (es) 2024-08-19
AU2023217824A1 (en) 2024-08-01
KR20240138086A (ko) 2024-09-20
CA3251212A1 (en) 2023-08-17

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