JP2025505381A - フタラジノン誘導体を含む抗癌剤との併用投与用薬学的組成物 - Google Patents
フタラジノン誘導体を含む抗癌剤との併用投与用薬学的組成物 Download PDFInfo
- Publication number
- JP2025505381A JP2025505381A JP2024543458A JP2024543458A JP2025505381A JP 2025505381 A JP2025505381 A JP 2025505381A JP 2024543458 A JP2024543458 A JP 2024543458A JP 2024543458 A JP2024543458 A JP 2024543458A JP 2025505381 A JP2025505381 A JP 2025505381A
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- combination
- cancer
- administered
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263302834P | 2022-01-25 | 2022-01-25 | |
| US63/302,834 | 2022-01-25 | ||
| PCT/IB2023/000030 WO2023144626A1 (en) | 2022-01-25 | 2023-01-25 | Pharmaceutical composition including phthalazinone derivative for co-administration with anticancer drug |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025505381A true JP2025505381A (ja) | 2025-02-26 |
| JP2025505381A5 JP2025505381A5 (https=) | 2026-02-02 |
Family
ID=87470837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024543458A Pending JP2025505381A (ja) | 2022-01-25 | 2023-01-25 | フタラジノン誘導体を含む抗癌剤との併用投与用薬学的組成物 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20250120970A1 (https=) |
| EP (1) | EP4469051A4 (https=) |
| JP (1) | JP2025505381A (https=) |
| KR (1) | KR20240138069A (https=) |
| CN (1) | CN118613264A (https=) |
| AU (1) | AU2023210923A1 (https=) |
| CA (1) | CA3249330A1 (https=) |
| CL (1) | CL2024002218A1 (https=) |
| IL (1) | IL314334A (https=) |
| JO (1) | JOP20240162A1 (https=) |
| MA (1) | MA66598A1 (https=) |
| MX (1) | MX2024009168A (https=) |
| TW (1) | TW202339753A (https=) |
| WO (1) | WO2023144626A1 (https=) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102372706A (zh) * | 2010-08-09 | 2012-03-14 | 江苏恒瑞医药股份有限公司 | 酞嗪酮类衍生物、其制备方法及其在医药上的应用 |
| EP2833883A4 (en) * | 2012-04-06 | 2015-12-23 | Indus Pharmaceuticals Inc | NOVEL COMPOSITIONS OF COMBINATIONS OF NONCOVALENT DNA BINDER AND CANCER-INHIBITING AND / OR INFLAMMATORY ACTIVE SUBSTANCES AND THEIR USE IN THE TREATMENT OF ILLNESSES |
| KR101670126B1 (ko) * | 2013-09-13 | 2016-10-27 | 일동제약(주) | 신규 프탈라지논 유도체 및 그 제조방법 |
| US12036222B2 (en) * | 2018-04-04 | 2024-07-16 | The Wistar Institut of Anatomy and Biology | Methods of treating cancers overexpressing CARM1 with EZH2 inhibitors and a PARP inhibitor |
| JP7626783B2 (ja) * | 2020-04-21 | 2025-02-07 | アイディーエンス カンパニー リミテッド | フタラジノン誘導体及びその中間体を調製するプロセス |
| AU2020444056A1 (en) * | 2020-04-21 | 2022-11-17 | Idience Co., Ltd. | Crystalline forms of phthalazinone compound |
-
2023
- 2023-01-25 EP EP23746538.0A patent/EP4469051A4/en active Pending
- 2023-01-25 CN CN202380018679.4A patent/CN118613264A/zh active Pending
- 2023-01-25 KR KR1020247022669A patent/KR20240138069A/ko active Pending
- 2023-01-25 MA MA66598A patent/MA66598A1/fr unknown
- 2023-01-25 CA CA3249330A patent/CA3249330A1/en active Pending
- 2023-01-25 JP JP2024543458A patent/JP2025505381A/ja active Pending
- 2023-01-25 WO PCT/IB2023/000030 patent/WO2023144626A1/en not_active Ceased
- 2023-01-25 IL IL314334A patent/IL314334A/en unknown
- 2023-01-25 US US18/730,930 patent/US20250120970A1/en active Pending
- 2023-01-25 AU AU2023210923A patent/AU2023210923A1/en active Pending
- 2023-01-25 MX MX2024009168A patent/MX2024009168A/es unknown
- 2023-01-30 TW TW112103190A patent/TW202339753A/zh unknown
-
2024
- 2024-07-23 JO JOJO/P/2024/0162A patent/JOP20240162A1/ar unknown
- 2024-07-23 CL CL2024002218A patent/CL2024002218A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MA66598A1 (fr) | 2024-11-29 |
| WO2023144626A1 (en) | 2023-08-03 |
| JOP20240162A1 (ar) | 2024-07-23 |
| CN118613264A (zh) | 2024-09-06 |
| EP4469051A4 (en) | 2025-12-17 |
| MX2024009168A (es) | 2024-08-09 |
| IL314334A (en) | 2024-09-01 |
| EP4469051A1 (en) | 2024-12-04 |
| US20250120970A1 (en) | 2025-04-17 |
| TW202339753A (zh) | 2023-10-16 |
| KR20240138069A (ko) | 2024-09-20 |
| CL2024002218A1 (es) | 2024-12-20 |
| AU2023210923A1 (en) | 2024-07-25 |
| CA3249330A1 (en) | 2023-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20260122 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20260122 |