JOP20240162A1 - تركيبة صيدلية تتضمن مشتق فثالازينون للإعطاء المشترك مع عقار مضاد للسرطان - Google Patents

تركيبة صيدلية تتضمن مشتق فثالازينون للإعطاء المشترك مع عقار مضاد للسرطان

Info

Publication number
JOP20240162A1
JOP20240162A1 JOJO/P/2024/0162A JOP20240162A JOP20240162A1 JO P20240162 A1 JOP20240162 A1 JO P20240162A1 JO P20240162 A JOP20240162 A JO P20240162A JO P20240162 A1 JOP20240162 A1 JO P20240162A1
Authority
JO
Jordan
Prior art keywords
administration
anticancer drug
formulation containing
derivative
phthalassone
Prior art date
Application number
JOJO/P/2024/0162A
Other languages
Arabic (ar)
English (en)
Inventor
Sungyeon Choi
In-Gyu Je
Eun-Jihn Roh
Jeong Eun Kim
Myongjae Lee
Won Sik Lee
Jong-Ha Lim
Kyoung Soo Ha
Minju Hong
Yeongran Yoo
Original Assignee
Idience Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idience Co Ltd filed Critical Idience Co Ltd
Publication of JOP20240162A1 publication Critical patent/JOP20240162A1/ar

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/502Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JOJO/P/2024/0162A 2022-01-25 2024-07-23 تركيبة صيدلية تتضمن مشتق فثالازينون للإعطاء المشترك مع عقار مضاد للسرطان JOP20240162A1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263302834P 2022-01-25 2022-01-25
PCT/IB2023/000030 WO2023144626A1 (en) 2022-01-25 2023-01-25 Pharmaceutical composition including phthalazinone derivative for co-administration with anticancer drug

Publications (1)

Publication Number Publication Date
JOP20240162A1 true JOP20240162A1 (ar) 2024-07-23

Family

ID=87470837

Family Applications (1)

Application Number Title Priority Date Filing Date
JOJO/P/2024/0162A JOP20240162A1 (ar) 2022-01-25 2024-07-23 تركيبة صيدلية تتضمن مشتق فثالازينون للإعطاء المشترك مع عقار مضاد للسرطان

Country Status (14)

Country Link
US (1) US20250120970A1 (https=)
EP (1) EP4469051A4 (https=)
JP (1) JP2025505381A (https=)
KR (1) KR20240138069A (https=)
CN (1) CN118613264A (https=)
AU (1) AU2023210923A1 (https=)
CA (1) CA3249330A1 (https=)
CL (1) CL2024002218A1 (https=)
IL (1) IL314334A (https=)
JO (1) JOP20240162A1 (https=)
MA (1) MA66598A1 (https=)
MX (1) MX2024009168A (https=)
TW (1) TW202339753A (https=)
WO (1) WO2023144626A1 (https=)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102372706A (zh) * 2010-08-09 2012-03-14 江苏恒瑞医药股份有限公司 酞嗪酮类衍生物、其制备方法及其在医药上的应用
EP2833883A4 (en) * 2012-04-06 2015-12-23 Indus Pharmaceuticals Inc NOVEL COMPOSITIONS OF COMBINATIONS OF NONCOVALENT DNA BINDER AND CANCER-INHIBITING AND / OR INFLAMMATORY ACTIVE SUBSTANCES AND THEIR USE IN THE TREATMENT OF ILLNESSES
KR101670126B1 (ko) * 2013-09-13 2016-10-27 일동제약(주) 신규 프탈라지논 유도체 및 그 제조방법
US12036222B2 (en) * 2018-04-04 2024-07-16 The Wistar Institut of Anatomy and Biology Methods of treating cancers overexpressing CARM1 with EZH2 inhibitors and a PARP inhibitor
JP7626783B2 (ja) * 2020-04-21 2025-02-07 アイディーエンス カンパニー リミテッド フタラジノン誘導体及びその中間体を調製するプロセス
AU2020444056A1 (en) * 2020-04-21 2022-11-17 Idience Co., Ltd. Crystalline forms of phthalazinone compound

Also Published As

Publication number Publication date
MA66598A1 (fr) 2024-11-29
WO2023144626A1 (en) 2023-08-03
CN118613264A (zh) 2024-09-06
EP4469051A4 (en) 2025-12-17
MX2024009168A (es) 2024-08-09
IL314334A (en) 2024-09-01
EP4469051A1 (en) 2024-12-04
US20250120970A1 (en) 2025-04-17
JP2025505381A (ja) 2025-02-26
TW202339753A (zh) 2023-10-16
KR20240138069A (ko) 2024-09-20
CL2024002218A1 (es) 2024-12-20
AU2023210923A1 (en) 2024-07-25
CA3249330A1 (en) 2023-08-03

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