JP2025504379A5 - - Google Patents
Info
- Publication number
- JP2025504379A5 JP2025504379A5 JP2024540912A JP2024540912A JP2025504379A5 JP 2025504379 A5 JP2025504379 A5 JP 2025504379A5 JP 2024540912 A JP2024540912 A JP 2024540912A JP 2024540912 A JP2024540912 A JP 2024540912A JP 2025504379 A5 JP2025504379 A5 JP 2025504379A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263296676P | 2022-01-05 | 2022-01-05 | |
| US63/296,676 | 2022-01-05 | ||
| PCT/US2023/010204 WO2023133201A1 (en) | 2022-01-05 | 2023-01-05 | Deuterium-enriched piperidinyl-methyl-purine amines and related compounds and their use in treating diseases and conditions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025504379A JP2025504379A (ja) | 2025-02-12 |
| JP2025504379A5 true JP2025504379A5 (https=) | 2026-01-14 |
| JPWO2023133201A5 JPWO2023133201A5 (https=) | 2026-01-14 |
Family
ID=87074217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024540912A Pending JP2025504379A (ja) | 2022-01-05 | 2023-01-05 | 重水素濃縮ピペリジニル－メチル－プリンアミン及び関連化合物、ならびに疾患及び状態の治療におけるそれらの使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12492203B2 (https=) |
| EP (1) | EP4460502A4 (https=) |
| JP (1) | JP2025504379A (https=) |
| KR (1) | KR20240158230A (https=) |
| CN (1) | CN119032094A (https=) |
| AU (1) | AU2023205553A1 (https=) |
| CA (1) | CA3242612A1 (https=) |
| IL (1) | IL314062A (https=) |
| MX (1) | MX2024008450A (https=) |
| WO (1) | WO2023133201A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021026803A1 (en) | 2019-08-14 | 2021-02-18 | Novartis Ag | Piperidinyl-methyl-purineamines as nsd2 inhibitors and anti-cancer agents |
| AU2023397773A1 (en) * | 2022-12-12 | 2025-06-26 | K36 Therapeutics, Inc. | Pharmaceutical compositions containing a piperidinyl-methyl-purine amine and their use in treating diseases and conditions |
| US20250171445A1 (en) * | 2023-11-17 | 2025-05-29 | K36 Therapeutics, Inc. | Deuterium-enriched piperidinyl-methyl-purine amine salts, crystalline forms, and their use in treating medical diseases and conditions |
| CN117843641B (zh) * | 2023-12-28 | 2025-04-25 | 和径医药科技（上海）有限公司 | Nsd3抑制剂及其制备方法和应用 |
| WO2025259850A1 (en) * | 2024-06-12 | 2025-12-18 | K36 Therapeutics, Inc. | Pharmaceutical compositions containing a deuterium-enriched piperidinyl-methyl-purine amine and their use in treating diseases and conditions |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010044981A2 (en) | 2008-09-18 | 2010-04-22 | Auspex Pharmaceutical ,Inc. | Benzoquinoline inhibitors of vesicular monoamine transporter 2 |
| EP2463289A1 (en) * | 2010-11-26 | 2012-06-13 | Almirall, S.A. | Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors |
| WO2021026803A1 (en) | 2019-08-14 | 2021-02-18 | Novartis Ag | Piperidinyl-methyl-purineamines as nsd2 inhibitors and anti-cancer agents |
| US20220380371A1 (en) | 2019-09-20 | 2022-12-01 | Novartis Ag | Mll1 inhibitors and anti-cancer agents |
| AR122159A1 (es) | 2020-05-28 | 2022-08-17 | Novartis Ag | Inhibidores de mll1 y agentes antineoplásicos |
| WO2023225154A1 (en) | 2022-05-18 | 2023-11-23 | K36 Therapeutics, Inc. | Piperidinyl-methyl-purine amine salts, crystalline forms, and their use in treating medical diseases and conditions |
| AU2023273656A1 (en) | 2022-05-18 | 2024-11-28 | K36 Therapeutics, Inc. | Piperidinyl-methyl-purine amine d-tartaric acid salts, crystalline forms, and their use in treating medical diseases and conditions |
| WO2023225150A1 (en) | 2022-05-18 | 2023-11-23 | K36 Therapeutics, Inc. | Piperidinyl-methyl-purine amine fumaric acid salts, crystalline forms, and their use in treating medical diseases and conditions |
| WO2023225144A1 (en) | 2022-05-18 | 2023-11-23 | K36 Therapeutics, Inc. | Piperidinyl-methyl-purine amine salts, crystalline forms, and their use in treating medical diseases and conditions |
| US20250361235A1 (en) | 2022-05-23 | 2025-11-27 | K36 Therapeutics, Inc. | Piperidinyl-methylpurine benzenes and related compounds and their use in treating diseases and conditions |
| US20250206740A1 (en) | 2022-05-23 | 2025-06-26 | K36 Therapeutics, Inc. | Piperidinyl-methylpurine pyrimidines and related compounds and their use in treating diseases and conditions |
| EP4583915A1 (en) | 2022-09-09 | 2025-07-16 | The Trustees Of Columbia University In The City Of New York | Methods of treating neuroendocrine prostate cancer (nepc) by inhibiting nuclear receptor binding set domain protein 2 (nsd2) |
| AU2023397773A1 (en) | 2022-12-12 | 2025-06-26 | K36 Therapeutics, Inc. | Pharmaceutical compositions containing a piperidinyl-methyl-purine amine and their use in treating diseases and conditions |
| US20250171445A1 (en) | 2023-11-17 | 2025-05-29 | K36 Therapeutics, Inc. | Deuterium-enriched piperidinyl-methyl-purine amine salts, crystalline forms, and their use in treating medical diseases and conditions |
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2023
- 2023-01-05 JP JP2024540912A patent/JP2025504379A/ja active Pending
- 2023-01-05 CA CA3242612A patent/CA3242612A1/en active Pending
- 2023-01-05 IL IL314062A patent/IL314062A/en unknown
- 2023-01-05 AU AU2023205553A patent/AU2023205553A1/en active Pending
- 2023-01-05 KR KR1020247026101A patent/KR20240158230A/ko active Pending
- 2023-01-05 WO PCT/US2023/010204 patent/WO2023133201A1/en not_active Ceased
- 2023-01-05 CN CN202380022643.3A patent/CN119032094A/zh active Pending
- 2023-01-05 EP EP23737585.2A patent/EP4460502A4/en active Pending
-
2024
- 2024-06-28 US US18/758,953 patent/US12492203B2/en active Active
- 2024-07-04 MX MX2024008450A patent/MX2024008450A/es unknown
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2025
- 2025-10-24 US US19/368,828 patent/US20260049083A1/en active Pending