JP2025509830A5 - - Google Patents
Info
- Publication number
- JP2025509830A5 JP2025509830A5 JP2024555344A JP2024555344A JP2025509830A5 JP 2025509830 A5 JP2025509830 A5 JP 2025509830A5 JP 2024555344 A JP2024555344 A JP 2024555344A JP 2024555344 A JP2024555344 A JP 2024555344A JP 2025509830 A5 JP2025509830 A5 JP 2025509830A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- composition according
- composition
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263319589P | 2022-03-14 | 2022-03-14 | |
| US63/319,589 | 2022-03-14 | ||
| PCT/US2023/015021 WO2023177592A1 (en) | 2022-03-14 | 2023-03-10 | Blood-brain barrier crossing mll1-wdr5 protein-protein interaction inhibitor compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025509830A JP2025509830A (ja) | 2025-04-11 |
| JP2025509830A5 true JP2025509830A5 (https=) | 2026-03-16 |
Family
ID=88024124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024555344A Pending JP2025509830A (ja) | 2022-03-14 | 2023-03-10 | 血液脳関門を通過するｍｌｌ１－ｗｄｒ５タンパク質間相互作用阻害剤化合物及びそれらの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230293539A1 (https=) |
| EP (1) | EP4493184A4 (https=) |
| JP (1) | JP2025509830A (https=) |
| KR (1) | KR20250009417A (https=) |
| CA (1) | CA3245866A1 (https=) |
| MX (1) | MX2024011346A (https=) |
| WO (1) | WO2023177592A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025090881A1 (en) * | 2023-10-27 | 2025-05-01 | Huyabio International, Llc | Combination therapies of wdr5 inhibitors and pd-1 inhibitors |
| WO2026058961A1 (en) | 2024-09-13 | 2026-03-19 | Alivexis, Inc. | Wdr5 inhibitors, compounds, pharmaceutical compositions, and methods of use thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8063058B2 (en) * | 2008-04-16 | 2011-11-22 | Portola Pharmaceuticals, Inc. | Inhibitors of syk and JAK protein kinases |
| US11319299B2 (en) * | 2016-03-01 | 2022-05-03 | Propellon Therapeutics Inc. | Substituted carboxamides as inhibitors of WDR5 protein-protein binding |
| CN107382840B (zh) * | 2016-05-16 | 2020-09-01 | 四川大学 | 吡啶类化合物及其作为idh功能变异突变体抑制剂类药物的用途 |
| WO2019046944A1 (en) * | 2017-09-06 | 2019-03-14 | Propellon Therapeutics Inc. | INHIBITORS OF PROTEIN BINDING WDR5-PROTEIN |
| CN108715585A (zh) * | 2018-04-23 | 2018-10-30 | 中国药科大学 | 苯基联三氮唑类mll1-wdr5蛋白-蛋白相互作用抑制剂 |
| EP4523755A3 (en) * | 2018-09-18 | 2025-06-11 | F. Hoffmann-La Roche AG | Quinazoline derivatives as antitumor agents |
| CN109734674B (zh) * | 2019-02-26 | 2022-08-26 | 中国药科大学 | 苯胺类wdr5蛋白-蛋白相互作用抑制剂及其制法和用途 |
| TWI899080B (zh) * | 2019-05-27 | 2025-10-01 | 大陸商迪哲（江蘇）醫藥股份有限公司 | Ｄｎａ依賴性蛋白激酶抑制劑 |
-
2023
- 2023-03-10 CA CA3245866A patent/CA3245866A1/en active Pending
- 2023-03-10 KR KR1020247034049A patent/KR20250009417A/ko active Pending
- 2023-03-10 WO PCT/US2023/015021 patent/WO2023177592A1/en not_active Ceased
- 2023-03-10 US US18/120,311 patent/US20230293539A1/en active Pending
- 2023-03-10 JP JP2024555344A patent/JP2025509830A/ja active Pending
- 2023-03-10 EP EP23771268.2A patent/EP4493184A4/en active Pending
-
2024
- 2024-09-13 MX MX2024011346A patent/MX2024011346A/es unknown
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