JP2025503502A5 - - Google Patents
Info
- Publication number
- JP2025503502A5 JP2025503502A5 JP2024538291A JP2024538291A JP2025503502A5 JP 2025503502 A5 JP2025503502 A5 JP 2025503502A5 JP 2024538291 A JP2024538291 A JP 2024538291A JP 2024538291 A JP2024538291 A JP 2024538291A JP 2025503502 A5 JP2025503502 A5 JP 2025503502A5
- Authority
- JP
- Japan
- Prior art keywords
- alkylene
- alkyl
- heterocycloalkyl
- cycloalkyl
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21217181.3 | 2021-12-22 | ||
| EP21217182 | 2021-12-22 | ||
| EP21217181 | 2021-12-22 | ||
| EP21217182.1 | 2021-12-22 | ||
| PCT/EP2022/087613 WO2023118507A2 (en) | 2021-12-22 | 2022-12-22 | Compounds and use thereof as hdac6 inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025503502A JP2025503502A (ja) | 2025-02-04 |
| JP2025503502A5 true JP2025503502A5 (https=) | 2026-01-07 |
Family
ID=84981649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024538291A Pending JP2025503502A (ja) | 2021-12-22 | 2022-12-22 | 化合物及びｈｄａｃ６阻害剤としてのその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20250051319A1 (https=) |
| EP (1) | EP4452265A2 (https=) |
| JP (1) | JP2025503502A (https=) |
| KR (1) | KR20240124952A (https=) |
| AU (1) | AU2022420827A1 (https=) |
| CA (1) | CA3239992A1 (https=) |
| IL (1) | IL313636A (https=) |
| MX (1) | MX2024007904A (https=) |
| WO (1) | WO2023118507A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018165520A1 (en) | 2017-03-10 | 2018-09-13 | Vps-3, Inc. | Metalloenzyme inhibitor compounds |
| AU2020321955A1 (en) | 2019-07-30 | 2022-03-17 | Eikonizo Therapapeutics, Inc. | HDAC6 inhibitors and uses thereof |
| AU2022420827A1 (en) * | 2021-12-22 | 2024-06-13 | Augustine Therapeutics | Compounds and use thereof as hdac6 inhibitors |
| TW202345813A (zh) | 2022-04-08 | 2023-12-01 | 美商艾科尼佐療法股份有限公司 | 㗁二唑ｈｄａｃ６抑制劑及其用途 |
| AU2024314277A1 (en) * | 2023-06-21 | 2025-11-13 | Augustine Therapeutics | Heteroaryl-amine compounds and use thereof as hdac6 inhibitors |
| WO2024261327A1 (en) * | 2023-06-21 | 2024-12-26 | Augustine Therapeutics | 2-(heteroaryl-thio)-1-(heteroaryl)ethanone compounds and use thereof as hdac6 inhibitors |
| WO2024261328A1 (en) * | 2023-06-21 | 2024-12-26 | Augustine Therapeutics | Amide-amine compounds and use thereof as hdac6 inhibitors |
| WO2026027696A1 (en) * | 2024-07-31 | 2026-02-05 | Augustine Therapeutics | Thiomethyl carbonyl compounds and use thereof as hdac6 inhibitors |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1217000A1 (en) | 2000-12-23 | 2002-06-26 | Aventis Pharma Deutschland GmbH | Inhibitors of factor Xa and factor VIIa |
| WO2005014588A1 (en) | 2003-08-01 | 2005-02-17 | Argenta Discovery Limited | Substituted thienyl-hydroxamic acids having histone deacetylase activity |
| US20090023798A1 (en) | 2007-06-15 | 2009-01-22 | Pharmacyclics, Inc. | Thiohydroxamates as inhibitors of histone deacetylase |
| CA2729909A1 (en) | 2008-07-14 | 2010-01-21 | Gilead Sciences, Inc. | Imidazolyl pyrimidine inhibitor compounds |
| GB0813403D0 (en) | 2008-07-22 | 2008-08-27 | Lectus Therapeutics Ltd | Potassium ion channel modulators & uses thereof |
| WO2011106627A1 (en) | 2010-02-26 | 2011-09-01 | Millennium Pharmaceuticals, Inc. | Substituted hydroxamic acids and uses thereof |
| WO2011147813A1 (de) * | 2010-05-27 | 2011-12-01 | Bayer Cropscience Ag | Heterocyclische thiosubstituierte alkanolderivate als fungizide |
| ES2647368T3 (es) | 2010-10-08 | 2017-12-21 | Vib Vzw | Inhibidores de HDAC para tratar la enfermedad de Charcot-Marie-Tooth |
| ES2635016T3 (es) | 2013-03-01 | 2017-10-02 | Fundación Para La Investigación Médica Aplicada | Nuevos compuestos como inhibidores duales de fosfodiesterasas e histonas deacetilasas |
| WO2017053360A1 (en) | 2015-09-22 | 2017-03-30 | The Board Of Trustees Of The University Of Illinois | Bicyclic and tricyclic cap bearing mercaptoacetamide derivatives as histone deacetylase inhibitors |
| US11584733B2 (en) * | 2017-01-09 | 2023-02-21 | Shuttle Pharmaceuticals, Inc. | Selective histone deacetylase inhibitors for the treatment of human disease |
| US12310967B2 (en) | 2017-12-21 | 2025-05-27 | Gliapharm Sa | Compositions and methods of treatment for neurological disorders comprising motor neuron diseases |
| ES2749743B2 (es) | 2018-09-21 | 2020-12-14 | Consejo Superior Investigacion | Derivados de purina inhibidores de cdc7 y su uso para el tratamiento de patologias neurologicas |
| US11339150B2 (en) * | 2019-12-27 | 2022-05-24 | Onkure, Inc. | Benzimidazole compounds as HDAC6 inhibitors |
| EP4111863A1 (en) | 2021-07-02 | 2023-01-04 | EuroChem Antwerpen | Phosphorus use efficiency enhancers as plant growth promotors |
| AU2022420827A1 (en) * | 2021-12-22 | 2024-06-13 | Augustine Therapeutics | Compounds and use thereof as hdac6 inhibitors |
| US20240139187A1 (en) | 2022-10-12 | 2024-05-02 | The Children's Medical Center Corporation | Selective hypothalamus permeable hdac6 inhibitors for treatment of leptin-resistant obesity |
-
2022
- 2022-12-22 AU AU2022420827A patent/AU2022420827A1/en active Pending
- 2022-12-22 JP JP2024538291A patent/JP2025503502A/ja active Pending
- 2022-12-22 MX MX2024007904A patent/MX2024007904A/es unknown
- 2022-12-22 IL IL313636A patent/IL313636A/en unknown
- 2022-12-22 CA CA3239992A patent/CA3239992A1/en active Pending
- 2022-12-22 US US18/723,237 patent/US20250051319A1/en active Pending
- 2022-12-22 WO PCT/EP2022/087613 patent/WO2023118507A2/en not_active Ceased
- 2022-12-22 EP EP22844102.8A patent/EP4452265A2/en active Pending
- 2022-12-22 KR KR1020247023082A patent/KR20240124952A/ko active Pending
-
2025
- 2025-01-10 US US19/016,827 patent/US12421222B2/en active Active
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