JP2025503052A5 - - Google Patents
Info
- Publication number
- JP2025503052A5 JP2025503052A5 JP2024543181A JP2024543181A JP2025503052A5 JP 2025503052 A5 JP2025503052 A5 JP 2025503052A5 JP 2024543181 A JP2024543181 A JP 2024543181A JP 2024543181 A JP2024543181 A JP 2024543181A JP 2025503052 A5 JP2025503052 A5 JP 2025503052A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- chloro
- phenyl
- pyrrolo
- pyrimidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2200753.8A GB202200753D0 (en) | 2022-01-21 | 2022-01-21 | Pharmaceutical compounds |
| GB2200753.8 | 2022-01-21 | ||
| PCT/EP2023/051447 WO2023139241A1 (en) | 2022-01-21 | 2023-01-20 | Heterocyclic compounds as ubiquitin specific protease 7 inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025503052A JP2025503052A (ja) | 2025-01-30 |
| JP2025503052A5 true JP2025503052A5 (https=) | 2026-01-05 |
Family
ID=80507367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024543181A Pending JP2025503052A (ja) | 2022-01-21 | 2023-01-20 | ユビキチン特異的プロテアーゼ７阻害剤としてのヘテロ環式化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250122223A1 (https=) |
| EP (1) | EP4466072A1 (https=) |
| JP (1) | JP2025503052A (https=) |
| CN (1) | CN118946566A (https=) |
| GB (1) | GB202200753D0 (https=) |
| WO (1) | WO2023139241A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202001980D0 (en) * | 2020-02-13 | 2020-04-01 | Almac Discovery Ltd | Therapeutic mentods |
| US20240150362A1 (en) | 2022-08-25 | 2024-05-09 | Molecure S.A. | Substituted Pyrrolotriazines |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2200753B (en) | 1986-12-23 | 1991-01-23 | Brookes & Gatehouse | Speed measurement device |
| EP1749822B1 (en) | 2005-08-05 | 2008-10-15 | Hybrigenics S.A. | Novel cysteine protease inhibitors and their therapeutic applications |
| US7875613B2 (en) | 2006-10-30 | 2011-01-25 | Hybrigenics Sa | Tetracyclic inhibitors of cysteine proteases, the pharmaceutical compositions thereof and their therapeutic applications |
| EP2208725A1 (en) | 2009-01-13 | 2010-07-21 | Hybrigenics S.A. | Novel specific inhibitors of ubiquitin specific protease 7, the pharmaceutical compositions thereof and their therapeutic applications |
| WO2010114881A1 (en) | 2009-04-01 | 2010-10-07 | Progenra Inc. | Anti-neoplastic compounds, compositions and methods |
| US20110177105A1 (en) | 2010-01-15 | 2011-07-21 | Roman Lopez | Novel Selective Inhibitors of Ubiquitin Specific Protease 7, the Pharmaceutical Compositions Thereof and Their Therapeutic Applications |
| EP2565186A1 (en) | 2011-09-02 | 2013-03-06 | Hybrigenics S.A. | Selective and reversible inhibitors of ubiquitin specific protease 7 |
| AR103297A1 (es) | 2014-12-30 | 2017-05-03 | Forma Therapeutics Inc | Pirrolo y pirazolopirimidinas como inhibidores de la proteasa 7 específica de ubiquitina |
| MA41291A (fr) | 2014-12-30 | 2017-11-07 | Forma Therapeutics Inc | Dérivés de la pyrrolotriazinone et de l'imidazotriazinone en tant qu'inhibiteurs de la protéase spécifique de l'ubiquitine n° 7 (usp7) pour le traitement d'un cancer |
| US9938300B2 (en) | 2015-02-05 | 2018-04-10 | Forma Therapeutics, Inc. | Isothiazolopyrimidinones, pyrazolopyrimidinones, and pyrrolopyrimidinones as ubiquitin-specific protease 7 inhibitors |
| US9840491B2 (en) | 2015-02-05 | 2017-12-12 | Forma Therapeutics, Inc. | Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors |
| EP3253765A1 (en) | 2015-02-05 | 2017-12-13 | Forma Therapeutics, Inc. | Thienopyrimidinones as ubiquitin-specific protease 7 inhibitors |
| CN107531683B (zh) | 2015-03-20 | 2022-05-13 | 豪夫迈·罗氏有限公司 | Usp7抑制剂化合物及使用方法 |
| GB201604647D0 (en) | 2016-03-18 | 2016-05-04 | Mission Therapeutics Ltd | Novel compounds |
| GB201604638D0 (en) | 2016-03-18 | 2016-05-04 | Mission Therapeutics Ltd | Novel compounds |
| GB201617758D0 (en) | 2016-10-20 | 2016-12-07 | Almac Discovery Limited | Pharmaceutical compounds |
| GB202001980D0 (en) | 2020-02-13 | 2020-04-01 | Almac Discovery Ltd | Therapeutic mentods |
-
2022
- 2022-01-21 GB GBGB2200753.8A patent/GB202200753D0/en not_active Ceased
-
2023
- 2023-01-20 WO PCT/EP2023/051447 patent/WO2023139241A1/en not_active Ceased
- 2023-01-20 US US18/729,403 patent/US20250122223A1/en active Pending
- 2023-01-20 EP EP23701878.3A patent/EP4466072A1/en active Pending
- 2023-01-20 JP JP2024543181A patent/JP2025503052A/ja active Pending
- 2023-01-20 CN CN202380027580.0A patent/CN118946566A/zh active Pending
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