JP2025501611A5 - - Google Patents

Info

Publication number
JP2025501611A5
JP2025501611A5 JP2024538275A JP2024538275A JP2025501611A5 JP 2025501611 A5 JP2025501611 A5 JP 2025501611A5 JP 2024538275 A JP2024538275 A JP 2024538275A JP 2024538275 A JP2024538275 A JP 2024538275A JP 2025501611 A5 JP2025501611 A5 JP 2025501611A5
Authority
JP
Japan
Prior art keywords
acid sequence
amino acid
domain
seq
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024538275A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025501611A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/081929 external-priority patent/WO2023122532A2/en
Publication of JP2025501611A publication Critical patent/JP2025501611A/ja
Publication of JP2025501611A5 publication Critical patent/JP2025501611A5/ja
Pending legal-status Critical Current

Links

JP2024538275A 2021-12-21 2022-12-19 糖尿病治療用Treg細胞を組換えるための組成物および方法 Pending JP2025501611A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202163292125P 2021-12-21 2021-12-21
US63/292,125 2021-12-21
US202263363918P 2022-04-29 2022-04-29
US63/363,918 2022-04-29
US202263364285P 2022-05-06 2022-05-06
US63/364,285 2022-05-06
US202263378928P 2022-10-10 2022-10-10
US63/378,928 2022-10-10
US202263384830P 2022-11-23 2022-11-23
US63/384,830 2022-11-23
PCT/US2022/081929 WO2023122532A2 (en) 2021-12-21 2022-12-19 Compositions and methods for engineering treg cells for treatment of diabetes

Publications (2)

Publication Number Publication Date
JP2025501611A JP2025501611A (ja) 2025-01-22
JP2025501611A5 true JP2025501611A5 (https=) 2025-11-25

Family

ID=86903699

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024538275A Pending JP2025501611A (ja) 2021-12-21 2022-12-19 糖尿病治療用Treg細胞を組換えるための組成物および方法

Country Status (7)

Country Link
US (1) US20250213686A1 (https=)
EP (1) EP4452286A4 (https=)
JP (1) JP2025501611A (https=)
AU (1) AU2022420487A1 (https=)
CA (1) CA3242057A1 (https=)
IL (1) IL313581A (https=)
WO (1) WO2023122532A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025255344A1 (en) * 2024-06-05 2025-12-11 Benaroya Research Institute At Virginia Mason Compositions and methods for engineering tregs for treatment of diabetes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009061442A1 (en) * 2007-11-06 2009-05-14 Children's Medical Center Corporation Method to produce induced pluripotent stem (ips) cells form non-embryonic human cells
WO2020264039A1 (en) * 2019-06-27 2020-12-30 Seattle Children's Hospital (dba Seattle Children's Research Institute) Artificial antigen-specific immunoregulatory t (airt) cells
EP4267171A4 (en) * 2020-12-22 2025-05-21 Seattle Children's Hospital (DBA Seattle Children's Research Institute) Antigen-specific immunoregulatory artificial T cells (AIRT)

Similar Documents

Publication Publication Date Title
KR102873899B1 (ko) 인터루킨-2 변이체 및 이의 사용 방법
TWI710572B (zh) 改善配對的t細胞受體
AU2017373815C1 (en) Novel T cell receptors and immune therapy using the same
ES2877129T3 (es) Sistema de señalización de receptor de antígeno quimérico (CAR)
CN110818802B (zh) 一种嵌合t细胞受体star及其应用
Haga-Friedman et al. Incorporation of transmembrane hydrophobic mutations in the TCR enhance its surface expression and T cell functional avidity
EP2585098B1 (en) Fzd8 extracellular domains and fzd8 extracellular domain fusion molecules for use in treating obesity and obesity-related disorders
WO2020252421A2 (en) Novel interleukin-2 variants and bifunctional fusion molecules thereof
CN105017429A (zh) 多聚体il-15可溶性融合分子与其制造与使用方法
KR20220110233A (ko) 펩티드-mhc ii 단백질 작제물 및 그의 용도
JPH09509944A (ja) T細胞調節のための製品と方法
EP2184297A1 (en) HLA-G polypeptides and pharmaceutical uses thereof
Romano et al. Molecular cloning and characterization of CD4 in an aquatic mammal, the white whale Delphinapterus leucas
EP3844175A1 (en) Combination therapies comprising pd-1-based chimeric proteins
JP2010509181A (ja) 融合ポリペプチドを細胞へ輸送する方法
US20220305117A1 (en) Combination of hepatitis b virus (hbv) vaccines and hbv-targeting rnai
JP2025501611A5 (https=)
JP2024500917A5 (https=)
CN106459175A (zh) 结合至源自人前胰岛素原(ppi)蛋白的alwgpdpaaa的t细胞受体
CN101688210B (zh) 促红细胞生成素融合蛋白
CN115151272B (zh) 嵌合抗原受体的优化
KR100719020B1 (ko) 재조합 아세틸콜린 수용체 폴리펩티드, 폴리펩티드 유도체및 이를 유효성분으로 포함하는 중증근무력증 치료제
US12115190B2 (en) IRF-4 engineered T cells and uses thereof in treating cancer
WO2026025111A1 (en) Nucleic acids and pharmaceutical compositions for immune cell engagers
IL304916A (en) Il-15 fusion proteins and methods of making and using same