JP2024500917A5 - - Google Patents

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Publication number
JP2024500917A5
JP2024500917A5 JP2023538672A JP2023538672A JP2024500917A5 JP 2024500917 A5 JP2024500917 A5 JP 2024500917A5 JP 2023538672 A JP2023538672 A JP 2023538672A JP 2023538672 A JP2023538672 A JP 2023538672A JP 2024500917 A5 JP2024500917 A5 JP 2024500917A5
Authority
JP
Japan
Prior art keywords
promoter
nucleotide sequence
sequence encoding
protein
tcrα
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023538672A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024500917A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/064561 external-priority patent/WO2022140354A1/en
Publication of JP2024500917A publication Critical patent/JP2024500917A/ja
Publication of JP2024500917A5 publication Critical patent/JP2024500917A5/ja
Pending legal-status Critical Current

Links

JP2023538672A 2020-12-22 2021-12-21 抗原特異的人工免疫制御性T(airT)細胞 Pending JP2024500917A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063129288P 2020-12-22 2020-12-22
US63/129,288 2020-12-22
US202163155486P 2021-03-02 2021-03-02
US63/155,486 2021-03-02
US202163179068P 2021-04-23 2021-04-23
US63/179,068 2021-04-23
US202163274375P 2021-11-01 2021-11-01
US63/274,375 2021-11-01
PCT/US2021/064561 WO2022140354A1 (en) 2020-12-22 2021-12-21 Artificial antigen-specific immunoregulatory t (airt) cells

Publications (2)

Publication Number Publication Date
JP2024500917A JP2024500917A (ja) 2024-01-10
JP2024500917A5 true JP2024500917A5 (https=) 2025-01-17

Family

ID=82159937

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023538672A Pending JP2024500917A (ja) 2020-12-22 2021-12-21 抗原特異的人工免疫制御性T(airT)細胞

Country Status (4)

Country Link
US (1) US20250186493A1 (https=)
EP (1) EP4267171A4 (https=)
JP (1) JP2024500917A (https=)
WO (1) WO2022140354A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL313581A (en) * 2021-12-21 2024-08-01 Benaroya Res Institute At Virginia Mason Preparations and methods for engineering TREG cells for the treatment of diabetes
WO2025255344A1 (en) * 2024-06-05 2025-12-11 Benaroya Research Institute At Virginia Mason Compositions and methods for engineering tregs for treatment of diabetes
WO2025259702A1 (en) * 2024-06-10 2025-12-18 Adoptracell, Inc. Method for generating car-t cells in which car expression is coupled with expression of endogenous foxp3, and compositions and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3042179A1 (en) * 2016-10-31 2018-05-03 Seattle Children's Hospital (dba Seattle Children's Research Institute) Method for treating autoimmune disease using cd4 t-cells with engineered stabilization of expression of endogenous foxp3 gene
JP7117015B2 (ja) * 2016-11-28 2022-08-12 メディジェン, インコーポレイテッド プラス鎖rnaウイルスによって引き起こされる感染疾患に対するワクチン
CN110191955B (zh) * 2016-12-13 2024-05-31 西雅图儿童医院(Dba西雅图儿童研究所) 在体外和体内对工程化的细胞中表达的化学物质诱导的信号传导复合物进行外源性药物激活的方法
MX2020011254A (es) * 2018-04-27 2020-11-12 Crispr Therapeutics Ag Celulas t car anti-bcma para agotamiento de celulas de plasma.
WO2019210057A1 (en) * 2018-04-27 2019-10-31 Seattle Children's Hospital (dba Seattle Children's Research Institute) Rapamycin resistant cells
WO2020264039A1 (en) * 2019-06-27 2020-12-30 Seattle Children's Hospital (dba Seattle Children's Research Institute) Artificial antigen-specific immunoregulatory t (airt) cells

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