JP2024500917A5 - - Google Patents
Info
- Publication number
- JP2024500917A5 JP2024500917A5 JP2023538672A JP2023538672A JP2024500917A5 JP 2024500917 A5 JP2024500917 A5 JP 2024500917A5 JP 2023538672 A JP2023538672 A JP 2023538672A JP 2023538672 A JP2023538672 A JP 2023538672A JP 2024500917 A5 JP2024500917 A5 JP 2024500917A5
- Authority
- JP
- Japan
- Prior art keywords
- promoter
- nucleotide sequence
- sequence encoding
- protein
- tcrα
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063129288P | 2020-12-22 | 2020-12-22 | |
| US63/129,288 | 2020-12-22 | ||
| US202163155486P | 2021-03-02 | 2021-03-02 | |
| US63/155,486 | 2021-03-02 | ||
| US202163179068P | 2021-04-23 | 2021-04-23 | |
| US63/179,068 | 2021-04-23 | ||
| US202163274375P | 2021-11-01 | 2021-11-01 | |
| US63/274,375 | 2021-11-01 | ||
| PCT/US2021/064561 WO2022140354A1 (en) | 2020-12-22 | 2021-12-21 | Artificial antigen-specific immunoregulatory t (airt) cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024500917A JP2024500917A (ja) | 2024-01-10 |
| JP2024500917A5 true JP2024500917A5 (https=) | 2025-01-17 |
Family
ID=82159937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023538672A Pending JP2024500917A (ja) | 2020-12-22 | 2021-12-21 | 抗原特異的人工免疫制御性T(airT)細胞 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20250186493A1 (https=) |
| EP (1) | EP4267171A4 (https=) |
| JP (1) | JP2024500917A (https=) |
| WO (1) | WO2022140354A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL313581A (en) * | 2021-12-21 | 2024-08-01 | Benaroya Res Institute At Virginia Mason | Preparations and methods for engineering TREG cells for the treatment of diabetes |
| WO2025255344A1 (en) * | 2024-06-05 | 2025-12-11 | Benaroya Research Institute At Virginia Mason | Compositions and methods for engineering tregs for treatment of diabetes |
| WO2025259702A1 (en) * | 2024-06-10 | 2025-12-18 | Adoptracell, Inc. | Method for generating car-t cells in which car expression is coupled with expression of endogenous foxp3, and compositions and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3042179A1 (en) * | 2016-10-31 | 2018-05-03 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Method for treating autoimmune disease using cd4 t-cells with engineered stabilization of expression of endogenous foxp3 gene |
| JP7117015B2 (ja) * | 2016-11-28 | 2022-08-12 | メディジェン, インコーポレイテッド | プラス鎖rnaウイルスによって引き起こされる感染疾患に対するワクチン |
| CN110191955B (zh) * | 2016-12-13 | 2024-05-31 | 西雅图儿童医院(Dba西雅图儿童研究所) | 在体外和体内对工程化的细胞中表达的化学物质诱导的信号传导复合物进行外源性药物激活的方法 |
| MX2020011254A (es) * | 2018-04-27 | 2020-11-12 | Crispr Therapeutics Ag | Celulas t car anti-bcma para agotamiento de celulas de plasma. |
| WO2019210057A1 (en) * | 2018-04-27 | 2019-10-31 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Rapamycin resistant cells |
| WO2020264039A1 (en) * | 2019-06-27 | 2020-12-30 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Artificial antigen-specific immunoregulatory t (airt) cells |
-
2021
- 2021-12-21 EP EP21912027.6A patent/EP4267171A4/en active Pending
- 2021-12-21 US US18/268,885 patent/US20250186493A1/en active Pending
- 2021-12-21 JP JP2023538672A patent/JP2024500917A/ja active Pending
- 2021-12-21 WO PCT/US2021/064561 patent/WO2022140354A1/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024500917A5 (https=) | ||
| Huang et al. | Airway inflammation and IgE production induced by dust mite allergen-specific memory/effector Th2 cell line can be effectively attenuated by IL-35 | |
| EP3645573B1 (en) | Novel t cell receptors and immune therapy using the same | |
| JP6706244B2 (ja) | Bcmaキメラ抗原受容体 | |
| JP2024138456A (ja) | 改変された制御性t細胞 | |
| JP2020527937A (ja) | 新規の細胞タグの発現 | |
| JP2024099698A5 (https=) | ||
| US20220340927A1 (en) | Methods and compositions for the modification and delivery of lymphocytes | |
| JP2019517267A5 (https=) | ||
| CA3017213A1 (en) | Genome edited immune effector cells | |
| EP3720453B1 (en) | Modified lymphocytes | |
| JP2020530993A (ja) | キメラ抗原受容体または改変tcrを発現し、選択的に発現されるヌクレオチド配列を含む細胞 | |
| JP2022513460A (ja) | 二量体形成剤調節性免疫受容体複合体 | |
| JP2021506271A (ja) | Daricインターロイキン受容体 | |
| US20180179260A1 (en) | Redirected cells with mhc chimeric receptors and methods of use in immunotherapy | |
| CN115427440A (zh) | 用于工程化细胞的嵌合受体 | |
| JP2023524853A5 (https=) | ||
| CA3151472A1 (en) | Chimeric cytokine receptors | |
| CN114901684B (zh) | 粒细胞集落刺激因子受体(g-csfr)的经修饰胞外结构域和结合其的细胞因子 | |
| EP4021484A1 (en) | Engineered regulatory t cell | |
| Brehm et al. | Humanized mice in translational immunology | |
| WO2018068257A1 (zh) | 通用型car-t细胞及其制备方法和用途 | |
| JP2025501611A5 (https=) | ||
| CN111808819A (zh) | 表达hla-g3异构体标准蛋白的细胞株及其应用 | |
| TW202334398A (zh) | 組成型細胞激素受體 |