JP2025500508A5 - - Google Patents
Info
- Publication number
- JP2025500508A5 JP2025500508A5 JP2024538418A JP2024538418A JP2025500508A5 JP 2025500508 A5 JP2025500508 A5 JP 2025500508A5 JP 2024538418 A JP2024538418 A JP 2024538418A JP 2024538418 A JP2024538418 A JP 2024538418A JP 2025500508 A5 JP2025500508 A5 JP 2025500508A5
- Authority
- JP
- Japan
- Prior art keywords
- liver
- pharmaceutical composition
- composition according
- cysteine
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020210185351A KR20230095666A (ko) | 2021-12-22 | 2021-12-22 | 간 표적 물질 및 이의 용도 |
| KR10-2021-0185351 | 2021-12-22 | ||
| PCT/KR2022/021129 WO2023121370A1 (ko) | 2021-12-22 | 2022-12-22 | 간 표적 물질 및 이의 용도 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025500508A JP2025500508A (ja) | 2025-01-09 |
| JP2025500508A5 true JP2025500508A5 (https=) | 2026-01-06 |
Family
ID=86903150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024538418A Pending JP2025500508A (ja) | 2021-12-22 | 2022-12-22 | 肝臓標的物質及びその用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250121086A1 (https=) |
| EP (1) | EP4454657A4 (https=) |
| JP (1) | JP2025500508A (https=) |
| KR (1) | KR20230095666A (https=) |
| CN (1) | CN118742317A (https=) |
| WO (1) | WO2023121370A1 (https=) |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| JP4046354B2 (ja) | 1996-03-18 | 2008-02-13 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | 増大した半減期を有する免疫グロブリン様ドメイン |
| RU2428430C2 (ru) | 2005-08-16 | 2011-09-10 | Ханми Холдингс Ко., Лтд. | СПОСОБ МАССОВОГО ПРОИЗВОДСТВА ОБЛАСТИ Fc ИММУНОГЛОБУЛИНА С УДАЛЕННЫМИ НАЧАЛЬНЫМИ МЕТИОНИНОВЫМИ ОСТАТКАМИ |
| US8703701B2 (en) * | 2009-12-18 | 2014-04-22 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
| KR101512702B1 (ko) | 2012-05-23 | 2015-04-16 | 포항공과대학교 산학협력단 | 금속 나노 입자 기반 간 표적 지향 약물 전달체 및 이의 제조방법 |
| CN104583232B (zh) * | 2012-06-21 | 2018-04-13 | 印第安纳大学研究及科技有限公司 | 展现gip受体活性的胰高血糖素类似物 |
| PE20171154A1 (es) | 2014-12-30 | 2017-08-16 | Hanmi Pharm Ind Co Ltd | Derivados de glucagon con estabilidad mejorada |
| EP4523705A3 (en) | 2015-06-30 | 2025-06-11 | Hanmi Pharm. Co., Ltd. | Glucagon derivative and a composition comprising a long acting conjugate of the same |
| EP3479841A4 (en) * | 2016-06-29 | 2020-03-04 | Hanmi Pharm. Co., Ltd. | GLUCAGON DERIVATIVE, CONJUGATE THEREOF, COMPOSITION THEREOF AND THERAPEUTIC USE THEREOF |
| WO2020071865A1 (ko) * | 2018-10-04 | 2020-04-09 | 한미약품 주식회사 | 글루카곤 및 이를 포함하는 조합물의 치료학적 용도 |
| DK3936142T3 (da) | 2019-06-28 | 2024-03-25 | Hanmi Pharmaceutical Co Ltd | Tredobbelt agonist med aktivitet med hensyn til alle glucagon-, GLP-1- og GLP-receptorer til behandling af leversygdom |
| KR20210040818A (ko) * | 2019-10-04 | 2021-04-14 | 한미약품 주식회사 | 글루카곤, 및 glp-1 수용체 및 gip 수용체 이중 작용제를 포함하는 조성물 및 이의 치료학적 용도 |
| EP4183407A4 (en) * | 2020-07-15 | 2024-08-14 | Hanmi Pharm. Co., Ltd. | THERAPEUTIC USE OF A GLUCAGNONE DERIVATIVE OR CONJUGATE THEREOF FOR LIVER DISEASES |
-
2021
- 2021-12-22 KR KR1020210185351A patent/KR20230095666A/ko active Pending
-
2022
- 2022-12-22 EP EP22912003.5A patent/EP4454657A4/en active Pending
- 2022-12-22 CN CN202280092331.5A patent/CN118742317A/zh active Pending
- 2022-12-22 US US18/723,147 patent/US20250121086A1/en active Pending
- 2022-12-22 WO PCT/KR2022/021129 patent/WO2023121370A1/ko not_active Ceased
- 2022-12-22 JP JP2024538418A patent/JP2025500508A/ja active Pending
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