JP2025500481A5 - - Google Patents
Info
- Publication number
- JP2025500481A5 JP2025500481A5 JP2024538257A JP2024538257A JP2025500481A5 JP 2025500481 A5 JP2025500481 A5 JP 2025500481A5 JP 2024538257 A JP2024538257 A JP 2024538257A JP 2024538257 A JP2024538257 A JP 2024538257A JP 2025500481 A5 JP2025500481 A5 JP 2025500481A5
- Authority
- JP
- Japan
- Prior art keywords
- saponin
- composition
- nucleic acid
- use according
- core structure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2030217 | 2021-12-22 | ||
| NL2030217 | 2021-12-22 | ||
| PCT/NL2022/050735 WO2023121445A1 (en) | 2021-12-22 | 2022-12-20 | Compositions comprising therapeutic nucleic acid and saponin for the treatment of muscle-wasting disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025500481A JP2025500481A (ja) | 2025-01-09 |
| JP2025500481A5 true JP2025500481A5 (https=) | 2025-12-23 |
Family
ID=81585487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024538257A Pending JP2025500481A (ja) | 2021-12-22 | 2022-12-20 | 筋消耗性障害を治療するための治療用核酸とサポニンとを含む組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20250250564A2 (https=) |
| EP (1) | EP4452281A1 (https=) |
| JP (1) | JP2025500481A (https=) |
| WO (1) | WO2023121445A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202100928QA (en) | 2018-08-02 | 2021-02-25 | Dyne Therapeutics Inc | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| US11168141B2 (en) | 2018-08-02 | 2021-11-09 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| CA3108282A1 (en) | 2018-08-02 | 2020-02-06 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US12370264B1 (en) | 2018-08-02 | 2025-07-29 | Dyne Therapeutics, Inc. | Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject |
| US12097263B2 (en) | 2018-08-02 | 2024-09-24 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| WO2020219820A1 (en) | 2019-04-25 | 2020-10-29 | Avidity Biosciences, Inc. | Nucleic acid compositions and methods of multi-exon skipping |
| US11771776B2 (en) | 2021-07-09 | 2023-10-03 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| IL316143A (en) | 2022-04-15 | 2024-12-01 | Dyne Therapeutics Inc | Muscle targeting complexes and formulations for the treatment of myotonic dystrophy |
| KR20260025101A (ko) * | 2023-06-02 | 2026-02-23 | 사프렘 테크놀로지스 비.브이. | 세포내 분자 표적을 통해 작용하는 치료적 이펙터 성분을 위한 개선된 치료 요법 |
| CN121270643B (zh) * | 2025-12-09 | 2026-03-17 | 成都健腾生物技术有限公司 | 一种麦仙翁皂苷e的生产制备工艺 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9204374A (es) | 1991-07-25 | 1993-03-01 | Idec Pharma Corp | Anticuerpo recombinante y metodo para su produccion. |
| US5739118A (en) * | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
| WO2004092329A2 (en) * | 2003-04-08 | 2004-10-28 | Galenica Pharmaceuticals, Inc. | Semi-synthetic saponin analogs with carrier and immune stimulatory activities for dna and rna vaccines |
| US10626395B2 (en) | 2016-10-27 | 2020-04-21 | The General Hospital Corporation | Therapeutic targeting of a microRNA to treat Duchenne muscular dystrophy |
| MX2019008199A (es) | 2017-01-06 | 2019-11-25 | Avidity Biosciences Llc | Composiciones de acido nucleico polipeptido y metodos de induccion de la omision de exon. |
| IL280536B2 (en) | 2018-08-02 | 2024-12-01 | Dyne Therapeutics Inc | Complexes targeting transferrin receptor and uses thereof |
| SG11202106603UA (en) | 2018-12-21 | 2021-07-29 | Sapreme Tech Bv | Biologically active cluster of molecules |
| CA3163283A1 (en) | 2020-01-10 | 2021-07-15 | Romesh R. Subramanian | Muscle targeting complexes and uses thereof for modulation of genes associated with muscle health |
-
2022
- 2022-12-20 JP JP2024538257A patent/JP2025500481A/ja active Pending
- 2022-12-20 US US18/723,163 patent/US20250250564A2/en active Pending
- 2022-12-20 EP EP22830620.5A patent/EP4452281A1/en active Pending
- 2022-12-20 WO PCT/NL2022/050735 patent/WO2023121445A1/en not_active Ceased
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