JP2025500481A - 筋消耗性障害を治療するための治療用核酸とサポニンとを含む組成物 - Google Patents

筋消耗性障害を治療するための治療用核酸とサポニンとを含む組成物 Download PDF

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JP2025500481A
JP2025500481A JP2024538257A JP2024538257A JP2025500481A JP 2025500481 A JP2025500481 A JP 2025500481A JP 2024538257 A JP2024538257 A JP 2024538257A JP 2024538257 A JP2024538257 A JP 2024538257A JP 2025500481 A JP2025500481 A JP 2025500481A
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saponin
nucleic acid
ligand
bond
dmd
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JP2025500481A5 (https=
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ヴェレナ ブイニー，ミリアム
ポステル，ルーベン
ヘアマンス，ガイ
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Sapreme Technologies BV
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Sapreme Technologies BV
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JP2024538257A 2021-12-22 2022-12-20 筋消耗性障害を治療するための治療用核酸とサポニンとを含む組成物 Pending JP2025500481A (ja)

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NL2030217 2021-12-22
NL2030217 2021-12-22
PCT/NL2022/050735 WO2023121445A1 (en) 2021-12-22 2022-12-20 Compositions comprising therapeutic nucleic acid and saponin for the treatment of muscle-wasting disorders

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JP2025500481A true JP2025500481A (ja) 2025-01-09
JP2025500481A5 JP2025500481A5 (https=) 2025-12-23

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US (1) US20250250564A2 (https=)
EP (1) EP4452281A1 (https=)
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SG11202100928QA (en) 2018-08-02 2021-02-25 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
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