JP2025500288A5 - - Google Patents

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Publication number
JP2025500288A5
JP2025500288A5 JP2024536366A JP2024536366A JP2025500288A5 JP 2025500288 A5 JP2025500288 A5 JP 2025500288A5 JP 2024536366 A JP2024536366 A JP 2024536366A JP 2024536366 A JP2024536366 A JP 2024536366A JP 2025500288 A5 JP2025500288 A5 JP 2025500288A5
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JP
Japan
Prior art keywords
seq
amino acid
sequence number
chain variable
variable domain
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Pending
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JP2024536366A
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English (en)
Japanese (ja)
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JP2025500288A (ja
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Priority claimed from PCT/EP2022/087829 external-priority patent/WO2023118608A1/en
Publication of JP2025500288A publication Critical patent/JP2025500288A/ja
Publication of JP2025500288A5 publication Critical patent/JP2025500288A5/ja
Pending legal-status Critical Current

Links

JP2024536366A 2021-12-23 2022-12-23 細胞療法に使用するためのcd45の識別可能な細胞表面タンパク質変異体 Pending JP2025500288A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21217465 2021-12-23
EP21217465.0 2021-12-23
PCT/EP2022/087829 WO2023118608A1 (en) 2021-12-23 2022-12-23 Discernible cell surface protein variants of cd45 for use in cell therapy

Publications (2)

Publication Number Publication Date
JP2025500288A JP2025500288A (ja) 2025-01-09
JP2025500288A5 true JP2025500288A5 (enExample) 2026-01-06

Family

ID=79171049

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024536366A Pending JP2025500288A (ja) 2021-12-23 2022-12-23 細胞療法に使用するためのcd45の識別可能な細胞表面タンパク質変異体

Country Status (10)

Country Link
EP (1) EP4452417A1 (enExample)
JP (1) JP2025500288A (enExample)
KR (1) KR20240119146A (enExample)
CN (1) CN118541158A (enExample)
AU (1) AU2022422572A1 (enExample)
CA (1) CA3240875A1 (enExample)
IL (1) IL313785A (enExample)
MX (1) MX2024007316A (enExample)
WO (1) WO2023118608A1 (enExample)
ZA (1) ZA202405124B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3110837A1 (en) 2018-08-28 2020-03-05 Vor Biopharma Inc. Genetically engineered hematopoietic stem cells and uses thereof
WO2026082736A1 (en) * 2024-10-14 2026-04-23 Cimeio Therapeutics Ag Chimeric antigen receptor (car) that targets receptor-type tyrosine phosphatase c (cd45) and its use to related applications

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170226209A1 (en) 2014-08-01 2017-08-10 INSERM (Institut National de la Santé et de la Recherche Médicale) An anti-cd45rc antibody for use as drug
GB201601073D0 (en) 2016-01-20 2016-03-02 Ucb Biopharma Sprl Antibodies
WO2017155937A1 (en) 2016-03-07 2017-09-14 Actinium Pharmaceuticals, Inc. Stabilized radiolabeled anti-cd45 immunoglobulin compositions
US11499168B2 (en) 2016-04-25 2022-11-15 Universitat Basel Allele editing and applications thereof
CN109641051A (zh) 2016-06-17 2019-04-16 美真达治疗公司 用于耗尽细胞的组合物和方法
LT3535392T (lt) 2016-11-02 2024-04-25 Universität Basel Imunologiškai atpažįstami ląstelių paviršiaus variantai, skirti naudoti ląstelių terapijoje
RU2019130504A (ru) 2017-02-28 2021-03-30 Вор Байофарма, Инк. Композиции и способы ингибирования линиеспецифических белков
WO2019084273A1 (en) 2017-10-25 2019-05-02 Actinium Pharmaceuticals, Inc. METHODS OF ANTI-CD45-BASED LYMPHODEPPLICATION AND USES THEREOF IN COMBINATION WITH ACT-BASED ANTICANCER THERAPIES
EP3498293A1 (en) 2017-12-15 2019-06-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Treatment of monogenic diseases with an anti-cd45rc antibody
CN109991410B (zh) 2017-12-29 2022-07-05 上海白泽医学检验所有限公司 一种含抗cd45单抗的组合物及其使用方法
WO2020018580A1 (en) 2018-07-16 2020-01-23 Fred Hutchinson Cancer Research Center Bispecific affinity reagent and related methods for pretargeted radioimmunotherapy against cd45+ cell
EP3626265A1 (en) 2018-09-21 2020-03-25 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-human cd45rc antibodies and uses thereof
EP3877416A4 (en) 2018-10-30 2022-07-27 Magenta Therapeutics, Inc. ANTI-CD45 ANTIBODIES AND CONJUGATES THEREOF
WO2020092655A1 (en) * 2018-10-30 2020-05-07 Magenta Therapeutics, Inc. Methods for allogeneic hematopoietic stem cell transplantation
WO2020159656A1 (en) 2019-02-01 2020-08-06 Actinium Pharmaceuticals, Inc. Molecules and their derivatives directed against cd45
WO2020170254A1 (en) 2019-02-21 2020-08-27 Ramot At Tel-Aviv University Ltd. Treatment of diseases with multimeric peptides

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