JP2025186368A5 - - Google Patents
Info
- Publication number
- JP2025186368A5 JP2025186368A5 JP2025151939A JP2025151939A JP2025186368A5 JP 2025186368 A5 JP2025186368 A5 JP 2025186368A5 JP 2025151939 A JP2025151939 A JP 2025151939A JP 2025151939 A JP2025151939 A JP 2025151939A JP 2025186368 A5 JP2025186368 A5 JP 2025186368A5
- Authority
- JP
- Japan
- Prior art keywords
- propan
- dihydro
- amino
- pyrimidine
- pyrrolo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062989104P | 2020-03-13 | 2020-03-13 | |
| US62/989,104 | 2020-03-13 | ||
| PCT/EP2021/056393 WO2021180952A1 (en) | 2020-03-13 | 2021-03-12 | Fused pyrimidine compounds as kcc2 |
| JP2022554784A JP7793529B2 (ja) | 2020-03-13 | 2021-03-12 | Ｋｃｃ２調節剤としての縮合ピリミジン化合物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022554784A Division JP7793529B2 (ja) | 2020-03-13 | 2021-03-12 | Ｋｃｃ２調節剤としての縮合ピリミジン化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025186368A JP2025186368A (ja) | 2025-12-23 |
| JP2025186368A5 true JP2025186368A5 (https=) | 2026-04-06 |
Family
ID=74874882
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022554784A Active JP7793529B2 (ja) | 2020-03-13 | 2021-03-12 | Ｋｃｃ２調節剤としての縮合ピリミジン化合物 |
| JP2025151939A Pending JP2025186368A (ja) | 2020-03-13 | 2025-09-12 | Ｋｃｃ２調節剤としての縮合ピリミジン化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022554784A Active JP7793529B2 (ja) | 2020-03-13 | 2021-03-12 | Ｋｃｃ２調節剤としての縮合ピリミジン化合物 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20230151013A1 (https=) |
| EP (1) | EP4103566B1 (https=) |
| JP (2) | JP7793529B2 (https=) |
| KR (1) | KR20220152319A (https=) |
| CN (4) | CN119735594A (https=) |
| AU (1) | AU2021234134B2 (https=) |
| BR (1) | BR112022018173A2 (https=) |
| CA (1) | CA3171192A1 (https=) |
| CL (1) | CL2022002386A1 (https=) |
| CO (1) | CO2022012884A2 (https=) |
| DK (1) | DK4103566T3 (https=) |
| ES (1) | ES2962136T3 (https=) |
| FI (1) | FI4103566T3 (https=) |
| HR (1) | HRP20231314T1 (https=) |
| HU (1) | HUE064037T2 (https=) |
| IL (1) | IL296265B2 (https=) |
| LT (1) | LT4103566T (https=) |
| MX (1) | MX2022011354A (https=) |
| PE (1) | PE20230106A1 (https=) |
| PL (1) | PL4103566T3 (https=) |
| PT (1) | PT4103566T (https=) |
| RS (1) | RS64823B1 (https=) |
| SI (1) | SI4103566T1 (https=) |
| SM (1) | SMT202300384T1 (https=) |
| WO (1) | WO2021180952A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240132285A (ko) * | 2021-12-08 | 2024-09-03 | 키네타, 인크. | 비시클릭 헤테로아렌 및 그의 사용 방법 |
| CN117843618A (zh) * | 2022-08-29 | 2024-04-09 | 北京沐华生物科技有限责任公司 | 一种ep300/cbp调节剂及其制备方法和用途 |
| CN121548571A (zh) * | 2023-04-05 | 2026-02-17 | 艾索尼斯治疗公司 | Kcc2增强剂及其用途 |
| WO2025188976A1 (en) * | 2024-03-06 | 2025-09-12 | Ovid Therapeutics Inc. | Fused amino pyrimidine compounds for treatment of neurodegenerative disorders |
| WO2025188977A1 (en) * | 2024-03-06 | 2025-09-12 | Ovid Therapeutics Inc. | Fused amino pyrimidine compounds for treatment of addiction and insomnia |
| US20260048062A1 (en) * | 2024-03-06 | 2026-02-19 | Ovid Therapeutics Inc. | Fused amino pyrimidine compounds for treatment of psychosis and psychotic disorders |
| WO2025188974A1 (en) * | 2024-03-06 | 2025-09-12 | Ovid Therapeutics Inc. | Fused amino pyrimidine compounds for treatment of autism spectrum disorder, obsessive compulsive disorder and tics |
| WO2025188951A1 (en) * | 2024-03-06 | 2025-09-12 | Ovid Therapeutics Inc. | Fused amino pyrimidine compounds for treatment of seizure disorders |
| WO2025188973A1 (en) * | 2024-03-06 | 2025-09-12 | Ovid Therapeutics Inc. | Fused amino pyrimidine compounds for treatment of 22q11.2 deletion/duplication syndromes |
| WO2025188953A1 (en) * | 2024-03-06 | 2025-09-12 | Ovid Therapeutics Inc. | Fused amino pyrimidine compounds for treatment of neuropathic and neuro-inflammatory pain |
| US20250281500A1 (en) * | 2024-03-06 | 2025-09-11 | Ovid Therapeutics Inc. | Fused amino pyrimidine compounds and pridopidine for treatment of huntington’s disease |
| US20250281498A1 (en) * | 2024-03-06 | 2025-09-11 | Ovid Therapeutics Inc. | Fused amino pyrimidine compounds for treatment of synucleinopathies and tdp-43 proteinopathies |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090099195A1 (en) * | 2007-05-08 | 2009-04-16 | Astrazeneca Ab | Therapeutic Compounds 570 |
| WO2015131080A1 (en) * | 2014-02-28 | 2015-09-03 | Nimbus Lakshmi, Inc. | Tyk2 inhibitors and uses thereof |
| WO2018217766A1 (en) * | 2017-05-22 | 2018-11-29 | Whitehead Institute For Biomedical Research | Kcc2 expression enhancing compounds and uses thereof |
| EP3675861A4 (en) * | 2017-09-01 | 2021-01-06 | Kadmon Corporation, LLC | ALPHA SUPERWINDING PROTEIN KINASE INHIBITORS ("COILED-COIL") ASSOCIATED WITH RHO |
| KR20210050493A (ko) * | 2018-05-25 | 2021-05-07 | 더 칠드런스 메디칼 센터 코포레이션 | 척수 손상의 치료 방법 |
-
2021
- 2021-03-12 SI SI202130073T patent/SI4103566T1/sl unknown
- 2021-03-12 BR BR112022018173A patent/BR112022018173A2/pt unknown
- 2021-03-12 KR KR1020227035465A patent/KR20220152319A/ko active Pending
- 2021-03-12 CN CN202411881483.0A patent/CN119735594A/zh active Pending
- 2021-03-12 MX MX2022011354A patent/MX2022011354A/es unknown
- 2021-03-12 SM SM20230384T patent/SMT202300384T1/it unknown
- 2021-03-12 DK DK21712145.8T patent/DK4103566T3/da active
- 2021-03-12 HU HUE21712145A patent/HUE064037T2/hu unknown
- 2021-03-12 IL IL296265A patent/IL296265B2/en unknown
- 2021-03-12 WO PCT/EP2021/056393 patent/WO2021180952A1/en not_active Ceased
- 2021-03-12 PE PE2022001943A patent/PE20230106A1/es unknown
- 2021-03-12 RS RS20231022A patent/RS64823B1/sr unknown
- 2021-03-12 CN CN202180020856.3A patent/CN115298182B/zh active Active
- 2021-03-12 US US17/911,051 patent/US20230151013A1/en active Pending
- 2021-03-12 CN CN202411881248.3A patent/CN119684299A/zh active Pending
- 2021-03-12 PT PT217121458T patent/PT4103566T/pt unknown
- 2021-03-12 JP JP2022554784A patent/JP7793529B2/ja active Active
- 2021-03-12 ES ES21712145T patent/ES2962136T3/es active Active
- 2021-03-12 EP EP21712145.8A patent/EP4103566B1/en active Active
- 2021-03-12 LT LTEPPCT/EP2021/056393T patent/LT4103566T/lt unknown
- 2021-03-12 HR HRP20231314TT patent/HRP20231314T1/hr unknown
- 2021-03-12 PL PL21712145.8T patent/PL4103566T3/pl unknown
- 2021-03-12 AU AU2021234134A patent/AU2021234134B2/en active Active
- 2021-03-12 CA CA3171192A patent/CA3171192A1/en active Pending
- 2021-03-12 FI FIEP21712145.8T patent/FI4103566T3/fi active
- 2021-03-12 CN CN202411881526.5A patent/CN119684300A/zh active Pending
-
2022
- 2022-09-01 CL CL2022002386A patent/CL2022002386A1/es unknown
- 2022-09-09 CO CONC2022/0012884A patent/CO2022012884A2/es unknown
-
2025
- 2025-09-12 JP JP2025151939A patent/JP2025186368A/ja active Pending
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