JP2025060882A5 - - Google Patents

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Publication number
JP2025060882A5
JP2025060882A5 JP2024230070A JP2024230070A JP2025060882A5 JP 2025060882 A5 JP2025060882 A5 JP 2025060882A5 JP 2024230070 A JP2024230070 A JP 2024230070A JP 2024230070 A JP2024230070 A JP 2024230070A JP 2025060882 A5 JP2025060882 A5 JP 2025060882A5
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JP
Japan
Prior art keywords
immune effector
vector
car
seq
effector cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024230070A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025060882A (ja
Filing date
Publication date
Priority claimed from PCT/EP2020/052867 external-priority patent/WO2020161186A1/en
Application filed filed Critical
Publication of JP2025060882A publication Critical patent/JP2025060882A/ja
Publication of JP2025060882A5 publication Critical patent/JP2025060882A5/ja
Pending legal-status Critical Current

Links

JP2024230070A 2019-02-08 2024-12-26 Cldn6発現癌の治療のためのキメラ抗原受容体改変細胞 Pending JP2025060882A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EPPCT/EP2019/053156 2019-02-08
EP2019053156 2019-02-08
PCT/EP2020/052867 WO2020161186A1 (en) 2019-02-08 2020-02-05 Chimeric antigen receptor-modified cells for the treatment of cldn6-expressing cancers
JP2021546261A JP7663500B2 (ja) 2019-02-08 2020-02-05 Cldn6発現癌の治療のためのキメラ抗原受容体改変細胞

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021546261A Division JP7663500B2 (ja) 2019-02-08 2020-02-05 Cldn6発現癌の治療のためのキメラ抗原受容体改変細胞

Publications (2)

Publication Number Publication Date
JP2025060882A JP2025060882A (ja) 2025-04-10
JP2025060882A5 true JP2025060882A5 (https=) 2025-10-07

Family

ID=69374312

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021546261A Active JP7663500B2 (ja) 2019-02-08 2020-02-05 Cldn6発現癌の治療のためのキメラ抗原受容体改変細胞
JP2024230070A Pending JP2025060882A (ja) 2019-02-08 2024-12-26 Cldn6発現癌の治療のためのキメラ抗原受容体改変細胞

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021546261A Active JP7663500B2 (ja) 2019-02-08 2020-02-05 Cldn6発現癌の治療のためのキメラ抗原受容体改変細胞

Country Status (26)

Country Link
US (1) US20220184119A1 (https=)
EP (2) EP3920939B1 (https=)
JP (2) JP7663500B2 (https=)
KR (1) KR20210124237A (https=)
CN (1) CN113727720A (https=)
AU (1) AU2020217868A1 (https=)
BR (1) BR112021015429A2 (https=)
CA (1) CA3129140A1 (https=)
CL (1) CL2021002067A1 (https=)
CO (1) CO2021010347A2 (https=)
CU (1) CU20210067A7 (https=)
DK (1) DK3920939T3 (https=)
ES (1) ES3002958T3 (https=)
FI (1) FI3920939T3 (https=)
HR (1) HRP20250016T1 (https=)
HU (1) HUE070174T2 (https=)
IL (1) IL285122A (https=)
LT (1) LT3920939T (https=)
MX (1) MX2021009507A (https=)
PL (1) PL3920939T3 (https=)
PT (1) PT3920939T (https=)
RS (1) RS66364B1 (https=)
SG (1) SG11202108339TA (https=)
SI (1) SI3920939T1 (https=)
SM (1) SMT202500012T1 (https=)
WO (1) WO2020161186A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021129927A1 (en) * 2019-12-23 2021-07-01 Biontech Cell & Gene Therapies Gmbh Treatment with immune effector cells engineered to express an antigen receptor
US20240238418A1 (en) * 2021-05-07 2024-07-18 University Of Florida Research Foundation, Inc. Car t cell therapy method
WO2024046572A1 (en) * 2022-09-01 2024-03-07 BioNTech SE Chimeric antigen receptor-modified cells for the treatment of cldn6 expressing cancer
JP2024545154A (ja) * 2021-12-09 2024-12-05 ビオンテック・ソシエタス・エウロパエア Cldn6発現がんの処置のためのキメラ抗原受容体改変細胞
CN114478802B (zh) * 2022-01-28 2023-05-26 郑州大学 一种嵌合抗原受体及其应用
CN114410588B (zh) * 2022-01-29 2022-11-04 西安电子科技大学 一种α1β1整合素依赖增强型CAR巨噬细胞及其制备方法和应用
CN119654342B (zh) * 2022-07-28 2025-07-18 乐普创一生物科技(上海)有限公司 抗MerTK抗体及其用途
US20260027209A1 (en) * 2022-07-29 2026-01-29 Legend Biotech Ireland Limited Claudin-6 binding moieties and uses thereof
CN120225555A (zh) * 2022-10-25 2025-06-27 恺兴生命科技(上海)有限公司 抗体及其应用
WO2025184170A1 (en) 2024-02-27 2025-09-04 Overt Bio, Inc. Methods and compositions for improving t cell function in an immunosuppressive environment
WO2026017108A1 (en) * 2024-07-19 2026-01-22 Primelink Biotherapeutics (Shenzhen) Co., Ltd. Cldn6 antibody and conjugates and use thereof

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
HK1047109A1 (zh) 1999-10-15 2003-02-07 University Of Massachusetts 作为指定基因干预工具的rna干预轨迹基因
US6326193B1 (en) 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
AU2001275474A1 (en) 2000-06-12 2001-12-24 Akkadix Corporation Materials and methods for the control of nematodes
WO2013143555A1 (en) 2012-03-26 2013-10-03 Biontech Ag Rna formulation for immunotherapy
ES2918501T3 (es) * 2013-12-19 2022-07-18 Novartis Ag Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
PT3514172T (pt) * 2014-04-01 2020-04-21 Tron Translationale Onkologie An Der Univ Der Johannes Gutenberg Univ Mainz Gemeinnuetzige Gmbh Imunorrecetores específicos de claudina-6 e epítopos de células t
MA40921A (fr) * 2014-11-05 2017-09-12 Abbvie Stemcentrx Llc Récepteurs antigéniques chimériques anti-cldn et procédés d'utilisation
CN106146666B (zh) * 2015-03-26 2019-09-06 科济生物医药(上海)有限公司 靶向cldn6的免疫效应细胞及其制备方法和应用
WO2016180467A1 (en) * 2015-05-11 2016-11-17 Biontech Cell & Gene Therapies Gmbh Enhancing the effect of car-engineered t cells by means of nucleic acid vaccination
US10233226B2 (en) * 2017-06-21 2019-03-19 The University Of North Carolina At Chapel Hill Methods and compositions for chimeric antigen receptor targeting cancer cells
KR20260026092A (ko) * 2017-09-19 2026-02-25 메사추세츠 인스티튜트 오브 테크놀로지 키메라 항원 수용체 t 세포 요법을 위한 조성물 및 그의 용도
CN109206524B (zh) * 2018-09-25 2022-04-05 山东兴瑞生物科技有限公司 抗Claudin18A2嵌合抗原受体、其修饰的T细胞及T细胞制备方法和用途

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