KR20210124237A - Cldn6를 발현하는 암을 치료하기 위한 키메라 항원 수용체-변형된 세포 - Google Patents

Cldn6를 발현하는 암을 치료하기 위한 키메라 항원 수용체-변형된 세포 Download PDF

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KR20210124237A
KR20210124237A KR1020217024706A KR20217024706A KR20210124237A KR 20210124237 A KR20210124237 A KR 20210124237A KR 1020217024706 A KR1020217024706 A KR 1020217024706A KR 20217024706 A KR20217024706 A KR 20217024706A KR 20210124237 A KR20210124237 A KR 20210124237A
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cells
cell
car
cldn6
immune effector
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우구르 사힌
페트라 오엠
벤자민 렝스틀
카싸리나 레인하드
크리스티나 마이클
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비온테크 쎌 & 제네 테라피스 게엠베하
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KR1020217024706A 2019-02-08 2020-02-05 Cldn6를 발현하는 암을 치료하기 위한 키메라 항원 수용체-변형된 세포 Pending KR20210124237A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP2019/053156 2019-02-08
EP2019053156 2019-02-08
PCT/EP2020/052867 WO2020161186A1 (en) 2019-02-08 2020-02-05 Chimeric antigen receptor-modified cells for the treatment of cldn6-expressing cancers

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KR20210124237A true KR20210124237A (ko) 2021-10-14

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US (1) US20220184119A1 (https=)
EP (2) EP4501351B1 (https=)
JP (2) JP7663500B2 (https=)
KR (1) KR20210124237A (https=)
CN (1) CN113727720A (https=)
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WO2021129927A1 (en) * 2019-12-23 2021-07-01 Biontech Cell & Gene Therapies Gmbh Treatment with immune effector cells engineered to express an antigen receptor
WO2024046572A1 (en) * 2022-09-01 2024-03-07 BioNTech SE Chimeric antigen receptor-modified cells for the treatment of cldn6 expressing cancer
CA3242106A1 (en) * 2021-12-09 2023-06-15 BioNTech SE Chimeric antigen receptor-modified cells for the treatment of cldn6 expressing cancer
CN114478802B (zh) * 2022-01-28 2023-05-26 郑州大学 一种嵌合抗原受体及其应用
CN114410588B (zh) * 2022-01-29 2022-11-04 西安电子科技大学 一种α1β1整合素依赖增强型CAR巨噬细胞及其制备方法和应用
CN120484126B (zh) * 2022-07-28 2025-11-18 乐普创一生物科技（上海）有限公司 抗MerTK抗体及其用途
WO2024022512A1 (en) * 2022-07-29 2024-02-01 Nanjing Legend Biotech Co., Ltd. Claudin-6 binding moieties and uses thereof
CN120225555A (zh) * 2022-10-25 2025-06-27 恺兴生命科技(上海)有限公司 抗体及其应用
WO2025184170A1 (en) 2024-02-27 2025-09-04 Overt Bio, Inc. Methods and compositions for improving t cell function in an immunosuppressive environment

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CA2386270A1 (en) 1999-10-15 2001-04-26 University Of Massachusetts Rna interference pathway genes as tools for targeted genetic interference
US6326193B1 (en) 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
AU2001275474A1 (en) 2000-06-12 2001-12-24 Akkadix Corporation Materials and methods for the control of nematodes
WO2013143555A1 (en) 2012-03-26 2013-10-03 Biontech Ag Rna formulation for immunotherapy
ES2918501T3 (es) 2013-12-19 2022-07-18 Novartis Ag Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
SI3126381T2 (sl) * 2014-04-01 2022-05-31 Biontech Cell&Gene Therapies Gmbh Claudin-6-specifični imunoreceptorji in t-celični epitopi
MA40921A (fr) 2014-11-05 2017-09-12 Abbvie Stemcentrx Llc Récepteurs antigéniques chimériques anti-cldn et procédés d'utilisation
CN106146666B (zh) * 2015-03-26 2019-09-06 科济生物医药（上海）有限公司 靶向cldn6的免疫效应细胞及其制备方法和应用
WO2016180467A1 (en) 2015-05-11 2016-11-17 Biontech Cell & Gene Therapies Gmbh Enhancing the effect of car-engineered t cells by means of nucleic acid vaccination
AU2018289428B2 (en) * 2017-06-21 2024-06-27 The General Hospital Corporation Methods and compositions for chimeric antigen receptor targeting cancer cells
WO2019060425A1 (en) * 2017-09-19 2019-03-28 Massachusetts Institute Of Technology COMPOSITIONS FOR CHIMERIC ANTIGENIC RECEPTOR T CELL THERAPY AND USES THEREOF
CN109206524B (zh) * 2018-09-25 2022-04-05 山东兴瑞生物科技有限公司 抗Claudin18A2嵌合抗原受体、其修饰的T细胞及T细胞制备方法和用途

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CA3129140A1 (en) 2020-08-13
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ES3002958T3 (en) 2025-03-10
EP4501351B1 (en) 2026-04-01
EP4501351A3 (en) 2025-05-07
BR112021015429A2 (pt) 2021-10-05
PL3920939T3 (pl) 2025-02-17
CO2021010347A2 (es) 2022-01-17
WO2020161186A1 (en) 2020-08-13
HRP20250016T1 (hr) 2025-03-14
CN113727720A (zh) 2021-11-30
AU2020217868A1 (en) 2021-08-12
MX2021009507A (es) 2021-09-08
DK3920939T3 (da) 2025-01-13
HUE070174T2 (hu) 2025-05-28
IL285122A (en) 2021-09-30
RS66364B1 (sr) 2025-01-31
EP4501351A2 (en) 2025-02-05
SMT202500012T1 (it) 2025-03-12
PT3920939T (pt) 2025-01-08
LT3920939T (lt) 2025-01-10
FI3920939T3 (fi) 2025-01-03
US20220184119A1 (en) 2022-06-16
EP3920939A1 (en) 2021-12-15
SG11202108339TA (en) 2021-08-30
JP7663500B2 (ja) 2025-04-16
JP2022520059A (ja) 2022-03-28
CL2021002067A1 (es) 2022-03-11
JP2025060882A (ja) 2025-04-10

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