JP2025038093A5 - - Google Patents

Download PDF

Info

Publication number
JP2025038093A5
JP2025038093A5 JP2024219599A JP2024219599A JP2025038093A5 JP 2025038093 A5 JP2025038093 A5 JP 2025038093A5 JP 2024219599 A JP2024219599 A JP 2024219599A JP 2024219599 A JP2024219599 A JP 2024219599A JP 2025038093 A5 JP2025038093 A5 JP 2025038093A5
Authority
JP
Japan
Prior art keywords
cells
pge2
composition
population
rapamycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024219599A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025038093A (ja
Filing date
Publication date
Priority claimed from JP2018537803A external-priority patent/JP7653759B2/ja
Application filed filed Critical
Publication of JP2025038093A publication Critical patent/JP2025038093A/ja
Publication of JP2025038093A5 publication Critical patent/JP2025038093A5/ja
Pending legal-status Critical Current

Links

JP2024219599A 2016-01-20 2024-12-16 養子免疫療法における免疫細胞調節のための組成物および方法 Pending JP2025038093A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662281064P 2016-01-20 2016-01-20
US62/281,064 2016-01-20
US201662402883P 2016-09-30 2016-09-30
US62/402,883 2016-09-30
JP2018537803A JP7653759B2 (ja) 2016-01-20 2017-01-20 養子免疫療法における免疫細胞調節のための組成物および方法
PCT/US2017/014449 WO2017127755A1 (en) 2016-01-20 2017-01-20 Compositions and methods for immune cell modulation in adoptive immunotherapies
JP2023000071A JP2023036919A (ja) 2016-01-20 2023-01-04 養子免疫療法における免疫細胞調節のための組成物および方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2023000071A Division JP2023036919A (ja) 2016-01-20 2023-01-04 養子免疫療法における免疫細胞調節のための組成物および方法

Publications (2)

Publication Number Publication Date
JP2025038093A JP2025038093A (ja) 2025-03-18
JP2025038093A5 true JP2025038093A5 (https=) 2025-04-02

Family

ID=59362155

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018537803A Active JP7653759B2 (ja) 2016-01-20 2017-01-20 養子免疫療法における免疫細胞調節のための組成物および方法
JP2023000071A Pending JP2023036919A (ja) 2016-01-20 2023-01-04 養子免疫療法における免疫細胞調節のための組成物および方法
JP2024219599A Pending JP2025038093A (ja) 2016-01-20 2024-12-16 養子免疫療法における免疫細胞調節のための組成物および方法

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2018537803A Active JP7653759B2 (ja) 2016-01-20 2017-01-20 養子免疫療法における免疫細胞調節のための組成物および方法
JP2023000071A Pending JP2023036919A (ja) 2016-01-20 2023-01-04 養子免疫療法における免疫細胞調節のための組成物および方法

Country Status (4)

Country Link
US (2) US11413309B2 (https=)
EP (1) EP3405568A4 (https=)
JP (3) JP7653759B2 (https=)
WO (1) WO2017127755A1 (https=)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3010236A1 (en) 2016-01-20 2017-07-27 Fate Therapeutics, Inc. Compositions and methods for immune cell modulation in adoptive immunotherapies
EP3405568A4 (en) 2016-01-20 2019-12-04 Fate Therapeutics, Inc. COMPOUNDS AND METHODS FOR IMMUNOCELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES
CN109072192B (zh) * 2016-02-16 2024-02-09 杜克大学 用于扩展和分化生产抗体的b细胞的方法
US11634686B2 (en) 2016-11-01 2023-04-25 Jian Feng Method of producing naive pluripotent stem cells
WO2018106595A1 (en) 2016-12-05 2018-06-14 Fate Therapeutics, Inc. Compositions and methods for immune cell modulation in adoptive immunotherapies
CN110546265A (zh) 2017-02-09 2019-12-06 因达普塔治疗公司 工程化自然杀伤(nk)细胞及其组合物和方法
EP3595683A1 (en) * 2017-03-15 2020-01-22 Orca Biosystems, Inc. Compositions and methods for hematopoietic stem cell transplants
WO2018183888A2 (en) 2017-03-31 2018-10-04 The Board Of Trustees Of The Leland Stanford Junior University Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling
KR102382431B1 (ko) * 2017-11-23 2022-04-01 베이징 이터널 머터리얼 테크놀로지 씨오., 엘티디 화합물 및 이를 이용한 유기 전계 발광 소자
US20210015859A1 (en) * 2017-12-08 2021-01-21 Fate Therapeutics, Inc. IMMUNOTHERAPIES USING ENHANCED iPSC DERIVED EFFECTOR CELLS
CA3083779A1 (en) 2017-12-22 2019-06-27 Fate Therapeutics, Inc. Enhanced immune effector cells and use thereof
KR20210126556A (ko) 2018-01-25 2021-10-20 미아 리바이트 개선된 면역치료 방법
JP7575271B2 (ja) * 2018-03-29 2024-10-29 フェイト セラピューティクス,インコーポレイテッド 操作された免疫エフェクター細胞およびその使用
US12410402B2 (en) 2018-11-21 2025-09-09 Indapta Therapeutics, Inc. Methods for expansion of natural killer (NK) cell subset and related compositions and methods
US12590148B2 (en) 2018-11-26 2026-03-31 Nkarta, Inc. Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
US20220040230A1 (en) * 2018-12-11 2022-02-10 The Regents Of The University Of California Compositions and methods for immunotherapies
AU2020232691B2 (en) 2019-03-05 2023-06-29 Nkarta, Inc. CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
US11697799B2 (en) 2019-04-15 2023-07-11 Ossium Health, Inc. System and method for extraction and cryopreservation of bone marrow
KR20220004028A (ko) 2019-04-26 2022-01-11 알로젠 테라퓨틱스 인코포레이티드 동종 car t 세포를 제조하는 방법
US11162079B2 (en) 2019-05-10 2021-11-02 The Regents Of The University Of California Blood type O Rh-hypo-immunogenic pluripotent cells
WO2020231882A2 (en) 2019-05-10 2020-11-19 The Regents Of The University Of California Modified pluripotent cells
JP2022551975A (ja) * 2019-10-15 2022-12-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Fc封鎖を介する移植細胞保護
CN110592016B (zh) * 2019-10-28 2020-10-02 上海科医联创生物科技有限公司 一种特异性t细胞的培养方法
CN110628717B (zh) * 2019-10-28 2020-10-30 上海科医联创生物科技有限公司 一种浸润性t细胞的培养方法
BR112022008215A2 (pt) * 2019-10-31 2022-07-12 Res Inst Nationwide Childrens Hospital Geração de células nk humanas primárias e expandidas knock-out de cd38
IL292924A (en) 2019-11-26 2022-07-01 Novartis Ag Chimeric antigen receptors cd19 and cd22 and their uses
MX2022006725A (es) * 2019-12-06 2022-08-22 Fate Therapeutics Inc Mejora de célula inmunitaria efectora derivada de ipsc mediante el uso de compuestos pequeños.
EP4087916A1 (en) * 2020-01-07 2022-11-16 The United States of America, as represented by the Secretary, Department of Health and Human Services Methods of producing t cell populations using induced pluripotent stem cells
AU2021292695A1 (en) 2020-06-19 2023-02-02 Fate Therapeutics, Inc. Combining iPSC-derived effector cell types for immunotherapy use
EP4181675A4 (en) 2020-07-18 2024-04-24 Ossium Health, Inc. PERMEATION OF WHOLE VERTEBRATE BODIES WITH A CRYOPRETECTIVE AGENT USING VACUUM-ASSISTED DIFFUSION
WO2022040504A2 (en) * 2020-08-21 2022-02-24 Georgetown University Stem cell-like memory t cells and uses thereof
EP4228406A4 (en) 2020-10-14 2024-11-13 Ossium Health, Inc. SYSTEMS AND METHODS FOR BONE MARROW EXTRACTION AND CRYOPRESERVATION
CN117279650A (zh) 2020-12-18 2023-12-22 奥瑟姆健康公司 细胞治疗方法
CN114763563B (zh) * 2021-01-12 2024-04-30 深圳华大临床检验中心 一种提高慢病毒感染效率的方法
EP4288069A4 (en) * 2021-02-07 2025-03-12 Baylor College of Medicine Engineered nkt cells for expansion and in vivo preservation and methods of use for the control of tumor cells
TW202307210A (zh) 2021-06-01 2023-02-16 瑞士商諾華公司 Cd19和cd22嵌合抗原受體及其用途
EP4504914A4 (en) 2022-04-08 2026-04-29 Fate Therapeutics Inc Cells having solid tumor targeting backbone and use thereof
CA3247010A1 (en) 2022-04-08 2023-10-12 Ono Pharmaceutical Co., Ltd. CHIMERIC ANTIGEN RECEPTOR FOR TUMOR TARGETING
WO2024211852A1 (en) * 2023-04-07 2024-10-10 Fate Therapeutics, Inc. Ipsc-derived nk cell for lymphoma treatment
WO2024243325A2 (en) * 2023-05-22 2024-11-28 The Board Of Trustees Of The University Of Illinois Combination of pac-1 and car t-cell treatments
CN116904400B (zh) * 2023-09-12 2023-12-01 成都以邦医药科技有限公司 可利霉素在体外car/tcr-t细胞产品制备过程优化中的应用
WO2025217183A1 (en) * 2024-04-09 2025-10-16 Board Of Regents, The University Of Texas System Prepared natural killer cells and uses thereof
CN119161336B (zh) * 2024-07-24 2025-09-05 四川大学 一种作为Blimp1抑制剂的小分子化合物及其用途

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL92382A (en) 1988-11-23 1994-12-29 Univ Michigan Use of a ligand specific for CD28 in the manufacture of medicament
NZ501276A (en) 1997-07-01 2000-10-27 Warner Lambert Co 4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors in treating proliferative disorders
AU770867B2 (en) 1999-08-13 2004-03-04 Fumie Sato Prostaglandin derivatives
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
DZ3401A1 (fr) 2000-07-19 2002-01-24 Warner Lambert Co Esters oxygenes d'acides 4-iodophenylamino benzhydroxamiques
SG2013013339A (en) 2002-03-13 2014-12-30 Array Biopharma Inc N3 alkylated benzimidazole derivatives as mek inhibitors
US20040175373A1 (en) 2002-06-28 2004-09-09 Xcyte Therapies, Inc. Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
US20050075276A1 (en) 2003-03-14 2005-04-07 Christopher Rudd Use of inhibitors of glycogen synthase-3 to augment CD28 dependent -T-cell responses
CA2546353A1 (en) 2003-11-19 2005-06-09 Array Biopharma Inc. Bicyclic inhibitors of mek and methods of use thereof
SG177981A1 (en) 2005-05-18 2012-02-28 Array Biopharma Inc 4-(phenylamino)-6-oxo-1, 6-dihydropyridazine-3-carboxamide derivatives as mek inhibitors for the treatment of hyperproliferative diseases
WO2007103901A2 (en) 2006-03-06 2007-09-13 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Autologous natural killer cells and lymphodepleting chemotherapy for the treatment of cancer
BRPI0714409A2 (pt) 2006-07-14 2013-03-12 Novartis Ag derivados de pirimidina como inibidores de alk-5
EP2094837B1 (en) 2006-12-14 2012-04-25 Medical Research Council Use of pi3k, m-tor and akt inhibitors to induce foxp3 expression and generate regulatory t cells
SG188904A1 (en) 2008-03-17 2013-04-30 Scripps Research Inst Combined chemical and genetic approaches for generation of induced pluripotent stem cells
CA2728739C (en) 2008-06-20 2017-07-11 Duke University Use of human cytomegalovirus antigens to enhance immune responses to cancer cells
EP4585589A3 (en) 2008-12-03 2025-11-19 The Scripps Research Institute Stem cell cultures
CN102281761A (zh) * 2009-01-14 2011-12-14 健康研究股份有限公司 用于增强免疫应答的方法和含有mTOR抑制剂的组合物
EP3399026B1 (en) 2010-06-14 2024-06-26 The Scripps Research Institute Reprogramming of cells to a new fate
ES2791716T3 (es) 2010-12-14 2020-11-05 Univ Maryland Células T que expresan al receptor de antígeno quimérico antietiqueta universal y métodos para el tratamiento del cáncer
EP2638896A1 (en) 2012-03-14 2013-09-18 Bioneer A/S Cationic liposomal drug delivery system for specific targeting of human cd14+ monocytes in whole blood
AU2014248119B2 (en) 2013-04-03 2019-06-20 Memorial Sloan-Kettering Cancer Center Effective generation of tumor-targeted T-cells derived from pluripotent stem cells
WO2015127548A1 (en) 2014-02-28 2015-09-03 The Royal Institution For The Advancement Of Learning / Mcgill University Tc-ptp inhibitors as apc activators for immunotherapy
US20170165230A1 (en) 2014-04-09 2017-06-15 Christopher Rudd Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity
US20150320754A1 (en) 2014-04-16 2015-11-12 Infinity Pharmaceuticals, Inc. Combination therapies
SI3151672T1 (sl) 2014-06-06 2021-03-31 Bluebird Bio, Inc. Izboljšani T-celični sestavki
ES2771926T3 (es) 2014-09-13 2020-07-07 Novartis Ag Terapias de combinación
US20180112180A1 (en) 2015-01-26 2018-04-26 Fate Therapeutics, Inc. Cells with increased immuno-regulatory properties and methods for their use and manufacture
AU2016211671B2 (en) 2015-01-26 2022-05-26 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
JP2018509459A (ja) 2015-03-27 2018-04-05 ナントクエスト インコーポレイテッド がん治療薬との併用療法におけるnk−92細胞
WO2016179283A1 (en) 2015-05-05 2016-11-10 Fate Therapeutics, Inc. Modulation of t lymphocytes
PT3294764T (pt) 2015-05-15 2021-02-15 Hope City Composições de recetores de antigénios quiméricos
WO2017040324A1 (en) 2015-08-28 2017-03-09 The Trustees Of The University Of Pennsylvania Methods and compositions for cells expressing a chimeric intracellular signaling molecule
CA3003152A1 (en) 2015-11-04 2017-05-11 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
CA3010236A1 (en) 2016-01-20 2017-07-27 Fate Therapeutics, Inc. Compositions and methods for immune cell modulation in adoptive immunotherapies
EP3405568A4 (en) 2016-01-20 2019-12-04 Fate Therapeutics, Inc. COMPOUNDS AND METHODS FOR IMMUNOCELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES
JP2019530470A (ja) * 2016-08-05 2019-10-24 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル γδFoxp3+調節性T細胞のエクスビボ生成及びその治療的使用
JP6987338B2 (ja) * 2016-08-05 2021-12-22 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル MHCII拘束性CD4+FOXP3+制御性T細胞のex vivo生成及びその治療的使用
WO2018106595A1 (en) 2016-12-05 2018-06-14 Fate Therapeutics, Inc. Compositions and methods for immune cell modulation in adoptive immunotherapies
CA3068604A1 (en) 2017-06-13 2018-12-20 Fate Therapeutics, Inc. Compositions and methods for inducing myeloid suppressive cells and use thereof
CN111511762B (zh) 2017-08-21 2025-05-06 天演药业公司 抗cd137分子及其用途

Similar Documents

Publication Publication Date Title
JP2025038093A5 (https=)
JP2019502725A5 (https=)
US20240002797A1 (en) Methods of cell culture for adoptive cell therapy
Consentius et al. Immunogenicity of allogeneic mesenchymal stromal cells: what has been seen in vitro and in vivo?
CN109628406B (zh) 一种治疗自身免疫疾病的间充质干细胞及其制备方法和应用
Morris et al. Advances in the understanding of acute graft‐versus‐host disease
ES2423993T3 (es) Proteínas HLA-G y usos farmacéuticos de las mismas
US20220380727A1 (en) Generation of engineered regulatory t cells
US20210061875A1 (en) Compositions and methods for treating autoimmune disease
CN109810947B (zh) 一种抑制Th17细胞活化的间充质干细胞及其制备方法和应用
US20170216417A1 (en) Population of immunoregulatory t cells specific for an irrelevant antigen and uses thereof for preventing or treating immune diseases
EP1771196B1 (en) Ccr ligands for stem cell homing
WO2022049306A1 (en) Mesenchymal stem cells co-expressing cxcr4 and il-10 and uses thereof
EP3873495B1 (en) Methods and compositions for treatment of type 1 diabetes using fibroblasts as facilitators of islet engraftment
JP5745419B2 (ja) 細胞、核酸構築物、前記構築物を含む細胞、及び疾患の治療において前記細胞を利用する方法
CN114340642A (zh) 用于胸腺再生和t细胞重建的组合物和方法
US20250353889A1 (en) Fusion protein for maintenance of regulatory t-cells
EP4320241A1 (en) Compositions and methods for delivery of therapeutic agents to acceptor cells
WO2024175738A1 (en) Method for thymus regeneration
US20250333697A1 (en) Tethered interleukin-2 recombinant receptors and methods of use
CN121586727A (zh) 组成型细胞因子受体
CN119768508A (zh) 重组细胞因子受体及其使用方法
Robertson et al. Immunological advantages of living donor kidney transplantation