JP2025024031A5 - - Google Patents

Download PDF

Info

Publication number
JP2025024031A5
JP2025024031A5 JP2024195152A JP2024195152A JP2025024031A5 JP 2025024031 A5 JP2025024031 A5 JP 2025024031A5 JP 2024195152 A JP2024195152 A JP 2024195152A JP 2024195152 A JP2024195152 A JP 2024195152A JP 2025024031 A5 JP2025024031 A5 JP 2025024031A5
Authority
JP
Japan
Prior art keywords
domain
cell
seq
intracellular
cd1a
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024195152A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025024031A (ja
Filing date
Publication date
Priority claimed from EP19382104.8A external-priority patent/EP3696191A1/en
Application filed filed Critical
Publication of JP2025024031A publication Critical patent/JP2025024031A/ja
Publication of JP2025024031A5 publication Critical patent/JP2025024031A5/ja
Pending legal-status Critical Current

Links

JP2024195152A 2019-02-14 2024-11-07 CD1a陽性癌の治療のためのCAR T細胞 Pending JP2025024031A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP19382104.8 2019-02-14
EP19382104.8A EP3696191A1 (en) 2019-02-14 2019-02-14 Car t-cells for the treatment of cd1a-positive cancer
JP2021547571A JP7590737B2 (ja) 2019-02-14 2020-02-13 CD1a陽性癌の治療のためのCAR T細胞
PCT/EP2020/053769 WO2020165350A1 (en) 2019-02-14 2020-02-13 Car t-cells for the treatment of cd1a-positive cancer

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021547571A Division JP7590737B2 (ja) 2019-02-14 2020-02-13 CD1a陽性癌の治療のためのCAR T細胞

Publications (2)

Publication Number Publication Date
JP2025024031A JP2025024031A (ja) 2025-02-19
JP2025024031A5 true JP2025024031A5 (https=) 2025-07-08

Family

ID=65685281

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021547571A Active JP7590737B2 (ja) 2019-02-14 2020-02-13 CD1a陽性癌の治療のためのCAR T細胞
JP2024195152A Pending JP2025024031A (ja) 2019-02-14 2024-11-07 CD1a陽性癌の治療のためのCAR T細胞

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021547571A Active JP7590737B2 (ja) 2019-02-14 2020-02-13 CD1a陽性癌の治療のためのCAR T細胞

Country Status (8)

Country Link
US (2) US12215158B2 (https=)
EP (2) EP3696191A1 (https=)
JP (2) JP7590737B2 (https=)
CN (2) CN113795506A (https=)
AU (1) AU2020222239B2 (https=)
CA (1) CA3128955A1 (https=)
MX (1) MX2021009798A (https=)
WO (1) WO2020165350A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3696191A1 (en) * 2019-02-14 2020-08-19 Fundación Instituto de Investigación contra la Leucemia Josep Carreras (IJC) Car t-cells for the treatment of cd1a-positive cancer
KR20230084212A (ko) 2020-10-09 2023-06-12 화이자 인코포레이티드 CD1a 항체 및 그의 용도
EP4347045A1 (en) * 2021-05-26 2024-04-10 Oxford University Innovation Limited Antibodies
IT202100027929A1 (it) * 2021-11-02 2023-05-02 Univ Degli Studi Magna Graecia Di Catanzaro Un nuovo anticorpo bispecifico asimmetrico(UMG2/CD1a-CD3e) per il trattamento immunologico della forma corticale di leucemia linfoblastica acuta T (T-ALL) pediatrica e dell’adulto
EP4234582A1 (en) * 2022-02-28 2023-08-30 Onechain Immunotherapeutics SL Humanized cd1a targeting moiety for the treatment of cd1a-positive cancer
CN119384436A (zh) * 2022-02-28 2025-01-28 单链免疫治疗有限公司 用于治疗CD1a阳性癌症的人源化CD1a靶向部分
GB202217923D0 (en) * 2022-11-29 2023-01-11 Univ Oxford Innovation Ltd Antibodies
EP4417623A1 (en) * 2023-02-15 2024-08-21 Fundació Institut de Recerca Contra la Leucèmia Josep Carreras Ccr9 targeting moiety for the treatment of ccr9-positive cancer
EP4667494A3 (en) * 2023-10-26 2026-03-04 Fundación Instituto de Investigación Sanitaria Fundación Jiménez Díaz Car t-cells against cd79b for the treatment of non-hodgkin lymphoma
CN119685260B (zh) * 2024-12-17 2026-01-13 上海交通大学医学院附属瑞金医院 一种具有新型穿膜区的嵌合抗原受体t细胞及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP0436597B1 (en) 1988-09-02 1997-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
DK0585287T3 (da) 1990-07-10 2000-04-17 Cambridge Antibody Tech Fremgangsmåde til fremstilling af specifikke bindingsparelementer
CA2095633C (en) 1990-12-03 2003-02-04 Lisa J. Garrard Enrichment method for variant proteins with altered binding properties
EP1820858B1 (en) 1991-03-01 2009-08-12 Dyax Corporation Chimeric protein comprising micro-protein having two or more disulfide bonds and embodiments thereof
ATE414768T1 (de) 1991-04-10 2008-12-15 Scripps Research Inst Bibliotheken heterodimerer rezeptoren mittels phagemiden
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
GB0717101D0 (en) * 2007-09-03 2007-10-10 Cambridge Entpr Ltd Tumour marker
KR20170066546A (ko) 2014-10-03 2017-06-14 노파르티스 아게 조합 요법
AU2016274989A1 (en) * 2015-06-12 2017-11-02 Immunomedics, Inc. Disease therapy with chimeric antigen receptor (car) constructs and t cells (car-t) or nk cells (car-nk) expressing car constructs
EP3696191A1 (en) * 2019-02-14 2020-08-19 Fundación Instituto de Investigación contra la Leucemia Josep Carreras (IJC) Car t-cells for the treatment of cd1a-positive cancer

Similar Documents

Publication Publication Date Title
JP2025024031A5 (https=)
JP2022520455A5 (https=)
CN110662771A (zh) 一种结合bcma的嵌合抗原受体(car)及其应用
JP2022534680A5 (https=)
JP2025028239A5 (https=)
JP2022501043A5 (https=)
FI3749338T3 (fi) Humanisoitu bcma vasta-aine ja bcma-car-t solut
JP2022523781A5 (https=)
JP2021087455A5 (https=)
JP2023524997A5 (https=)
JP2020533958A5 (https=)
KR20050108349A (ko) 영속적인 티 세포 반응을 유도하는 삼량체 폴리펩티드 구조물
TWI754211B (zh) 新型雙特異性cd3/cd20多肽複合物
WO2017030926A1 (en) Bispecific monovalent diabodies that are capable of binding b7-h3 and cd3, and uses thereof
JP2021500881A5 (https=)
TW202246330A (zh) 改良的雙特異性多肽分子
JP2025508343A5 (https=)
CA3102331A1 (en) Novel anti-sirpa antibodies
JP2024534847A5 (https=)
IL273393B1 (en) New anti-CD3 epsilon antibodies
CN111484555A (zh) 新型双特异性cd3/cd20多肽复合物
JP2024153077A (ja) 微小ガイダンス及びナビゲーションコントロール(miniGNC)抗体様タンパク質、その製造方法及び使用方法
IL274806B1 (en) T-cells comprising anti-cd38 and anti-cd138 chimeric antigen receptors and uses thereof
EP4490194A1 (en) Novel anti-cd3 antibodies and uses thereof
CN116917316A (zh) 与NKp30结合的抗体分子及其用途