JP2024546842A5 - - Google Patents

Info

Publication number
JP2024546842A5
JP2024546842A5 JP2024535370A JP2024535370A JP2024546842A5 JP 2024546842 A5 JP2024546842 A5 JP 2024546842A5 JP 2024535370 A JP2024535370 A JP 2024535370A JP 2024535370 A JP2024535370 A JP 2024535370A JP 2024546842 A5 JP2024546842 A5 JP 2024546842A5
Authority
JP
Japan
Prior art keywords
fusion protein
protein according
domain
antibody
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024535370A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024546842A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/081559 external-priority patent/WO2023114847A2/en
Publication of JP2024546842A publication Critical patent/JP2024546842A/ja
Publication of JP2024546842A5 publication Critical patent/JP2024546842A5/ja
Pending legal-status Critical Current

Links

JP2024535370A 2021-12-14 2022-12-14 疾患を治療するための組成物及び方法 Pending JP2024546842A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163289595P 2021-12-14 2021-12-14
US63/289,595 2021-12-14
US202263368119P 2022-07-11 2022-07-11
US63/368,119 2022-07-11
PCT/US2022/081559 WO2023114847A2 (en) 2021-12-14 2022-12-14 Compositions and methods for treating disease

Publications (2)

Publication Number Publication Date
JP2024546842A JP2024546842A (ja) 2024-12-26
JP2024546842A5 true JP2024546842A5 (https=) 2025-12-17

Family

ID=85157400

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024535370A Pending JP2024546842A (ja) 2021-12-14 2022-12-14 疾患を治療するための組成物及び方法

Country Status (7)

Country Link
US (1) US20250129136A1 (https=)
EP (1) EP4448561A2 (https=)
JP (1) JP2024546842A (https=)
KR (1) KR20240125951A (https=)
AU (1) AU2022409708A1 (https=)
CA (1) CA3240528A1 (https=)
WO (1) WO2023114847A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023183474A1 (en) * 2022-03-23 2023-09-28 Bodhi Bio Llc Antigen-specific therapy for autoimmune diseases
WO2024189620A1 (en) * 2023-03-13 2024-09-19 Canopy Immuno-Therapeutics Ltd. Ig-like fusion proteins for treating pemphigus vulgaris and foliaceus
WO2025253854A1 (ja) * 2024-06-04 2025-12-11 国立大学法人京都大学 B細胞受容体を発現する細胞の傷害及び/又は除去剤、該剤を含む自己免疫疾患の治療剤及び医薬組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5132405A (en) 1987-05-21 1992-07-21 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5892019A (en) 1987-07-15 1999-04-06 The United States Of America, As Represented By The Department Of Health And Human Services Production of a single-gene-encoded immunoglobulin
US5350741A (en) 1988-07-30 1994-09-27 Kanji Takada Enteric formulations of physiologically active peptides and proteins
JPH0977800A (ja) * 1995-09-12 1997-03-25 Takeji Nishikawa 融合蛋白質、並びに落葉状天疱瘡の治療薬、治療器具、診断剤及び抗体測定方法
AU2001295503A1 (en) 2000-08-22 2002-03-04 Micromet Ag Composition for the elimination of autoreactive b-cells
EP2050466B1 (en) * 2006-08-14 2015-10-28 Chugai Seiyaku Kabushiki Kaisha Diagnosis and treatment of cancer using anti-desmoglein-3 antibodies
EP2123754B1 (en) * 2007-01-30 2011-04-06 Forerunner Pharma Research Co., Ltd. CHIMERIC Fc GAMMA RECEPTOR AND METHOD FOR DETERMINATION OF ADCC ACTIVITY BY USING THE RECEPTOR

Similar Documents

Publication Publication Date Title
US20240124584A1 (en) Igm fc and j-chain mutations that affect igm serum half-life
JP2024546842A5 (https=)
CN112119097B (zh) 自然杀伤细胞接合抗体融合构建体
KR102745676B1 (ko) 항-bcma 중쇄-단독 항체
TWI373343B (en) Antibodies that bind human interleukin-18 and methods of making and using
US9908938B2 (en) Bispecific molecules that are immunoreactive with immune effector cells that express an activating receptor and an antigen expressed by a cell infected by a virus and uses thereof
RU2770209C2 (ru) Терапевтические антитела против лиганда cd40
CN113710707A (zh) 结合于psma的重链抗体
EP1260521A2 (en) Immunoglobulin variants for specific Fc epsilon receptors
JP2005538706A (ja) スーパーヒト化抗体
CN109219617A (zh) Bcma和cd3双特异性t细胞接合抗体构建体
CN109476734A (zh) Cd70和cd3的抗体构建体
CN105531370A (zh) 治疗靶向特异性vnar结构域与icosl的分离
US20230212293A1 (en) Pd-1 agonist multimeric binding molecules
US12378326B2 (en) Anti-CD28 x anti-PSMA antibodies
JP6966330B2 (ja) Iii型分泌装置標的化分子
JP7080219B2 (ja) 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体
US20230383012A1 (en) Antibodies that bind pd-l1, pd-l2, and/or cd28
US20220306760A1 (en) Igm glycovariants
JP6640232B2 (ja) クロストリジウム・ディフィシル感染症の治療のための、クロストリジウム・ディフィシルのトキシンa及びトキシンbに対する四重特異性の八量体型結合剤及び抗体
AU2019277546A1 (en) Nav1.7 monoclonal antibody
US20250122299A1 (en) ANTI-CD20 x ANTI-CD28 COMBINATION THERAPIES
JP2007527703A (ja) 肺炎球菌表面付着因子Aタンパク質(PsaA)に関する結合メンバー
TW202144425A (zh) 特異性抗原結合分子,其製備方法及醫藥用途
WO2024094151A1 (en) Multi-specific antibody and medical use thereof