JP2024546095A5 - - Google Patents
Info
- Publication number
- JP2024546095A5 JP2024546095A5 JP2024533954A JP2024533954A JP2024546095A5 JP 2024546095 A5 JP2024546095 A5 JP 2024546095A5 JP 2024533954 A JP2024533954 A JP 2024533954A JP 2024533954 A JP2024533954 A JP 2024533954A JP 2024546095 A5 JP2024546095 A5 JP 2024546095A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- independently
- compound according
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163287962P | 2021-12-09 | 2021-12-09 | |
| US63/287,962 | 2021-12-09 | ||
| PCT/US2022/052228 WO2023107606A1 (en) | 2021-12-09 | 2022-12-08 | Bcl-xl/bcl-2 dual degraders for treatment of cancers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024546095A JP2024546095A (ja) | 2024-12-17 |
| JP2024546095A5 true JP2024546095A5 (cg-RX-API-DMAC7.html) | 2025-12-04 |
Family
ID=85036966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024533954A Pending JP2024546095A (ja) | 2021-12-09 | 2022-12-08 | 癌の処置のためのｂｃｌ－ｘｌ／ｂｃｌ－２二重分解物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250154141A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP4444717A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2024546095A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20240118146A (cg-RX-API-DMAC7.html) |
| CN (1) | CN118660886A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2022405016A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3241668A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2023107606A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113660937A (zh) * | 2019-02-08 | 2021-11-16 | 佛罗里达大学研究基金公司 | 治疗剂和治疗方法 |
| US12441722B2 (en) | 2020-01-15 | 2025-10-14 | University Of Florida Research Foundation, Incorporated | Therapeutic agents and methods of treatment |
| WO2025129024A1 (en) * | 2023-12-13 | 2025-06-19 | University Of Florida Research Foundation, Incorporated | Cereblon-recruiting degraders of antiapoptotic bcl-2 proteins |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002097053A2 (en) | 2001-05-30 | 2002-12-05 | The Regents Of The University Of Michigan | Small molecule antagonists of bcl2 family proteins |
| ES2382377T3 (es) | 2003-05-30 | 2012-06-07 | Gemin X Pharmaceuticals Canada Inc. | Compuestos triheterocíclicos, composiciones, y métodos para tratar cáncer |
| US7973161B2 (en) | 2003-11-13 | 2011-07-05 | Abbott Laboratories | Apoptosis promoters |
| AU2005277223C1 (en) | 2004-08-20 | 2009-05-21 | The Regents Of The University Of Michigan | Small molecule inhibitors of anti-apoptotic Bcl-2 family members and the uses thereof |
| US8039668B2 (en) | 2008-10-17 | 2011-10-18 | Burnham Institute For Medical Research | Naphthalene-based inhibitors of anti-apoptotic proteins |
| US8168784B2 (en) | 2008-06-20 | 2012-05-01 | Abbott Laboratories | Processes to make apoptosis promoters |
| WO2010138588A2 (en) | 2009-05-26 | 2010-12-02 | Abbott Laboratories | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
| AU2012255251B2 (en) | 2011-05-18 | 2017-06-15 | University Of Florida Research Foundation, Inc. | Macrocyclic therapeutic agents and methods of treatment |
| CN113660937A (zh) | 2019-02-08 | 2021-11-16 | 佛罗里达大学研究基金公司 | 治疗剂和治疗方法 |
| US12219938B2 (en) * | 2020-10-19 | 2025-02-11 | University Of Florida Research Foundation, Incorporated | Mouse model of alcohol-induced liver cancer |
-
2022
- 2022-12-08 CA CA3241668A patent/CA3241668A1/en active Pending
- 2022-12-08 CN CN202280091197.7A patent/CN118660886A/zh active Pending
- 2022-12-08 AU AU2022405016A patent/AU2022405016A1/en active Pending
- 2022-12-08 US US18/717,509 patent/US20250154141A1/en active Pending
- 2022-12-08 EP EP22847326.0A patent/EP4444717A1/en active Pending
- 2022-12-08 JP JP2024533954A patent/JP2024546095A/ja active Pending
- 2022-12-08 WO PCT/US2022/052228 patent/WO2023107606A1/en not_active Ceased
- 2022-12-08 KR KR1020247022837A patent/KR20240118146A/ko active Pending