JP2024545602A5 - - Google Patents

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Publication number
JP2024545602A5
JP2024545602A5 JP2024529302A JP2024529302A JP2024545602A5 JP 2024545602 A5 JP2024545602 A5 JP 2024545602A5 JP 2024529302 A JP2024529302 A JP 2024529302A JP 2024529302 A JP2024529302 A JP 2024529302A JP 2024545602 A5 JP2024545602 A5 JP 2024545602A5
Authority
JP
Japan
Prior art keywords
nucleotide
double
stranded oligonucleotide
hsd17b13
skeletal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024529302A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024545602A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/050371 external-priority patent/WO2023091644A2/en
Publication of JP2024545602A publication Critical patent/JP2024545602A/ja
Publication of JP2024545602A5 publication Critical patent/JP2024545602A5/ja
Pending legal-status Critical Current

Links

JP2024529302A 2021-11-19 2022-11-18 Hsd17b13関連二本鎖オリゴヌクレオチド組成物及びそれに関連する方法 Pending JP2024545602A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163264360P 2021-11-19 2021-11-19
US63/264,360 2021-11-19
US202263268775P 2022-03-02 2022-03-02
US63/268,775 2022-03-02
US202263377482P 2022-09-28 2022-09-28
US63/377,482 2022-09-28
PCT/US2022/050371 WO2023091644A2 (en) 2021-11-19 2022-11-18 Hsd17b13-related double stranded oligonucleotide compositions and methods relating thereto

Publications (2)

Publication Number Publication Date
JP2024545602A JP2024545602A (ja) 2024-12-10
JP2024545602A5 true JP2024545602A5 (enExample) 2025-11-27

Family

ID=86397758

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024529302A Pending JP2024545602A (ja) 2021-11-19 2022-11-18 Hsd17b13関連二本鎖オリゴヌクレオチド組成物及びそれに関連する方法

Country Status (4)

Country Link
US (1) US20240384273A1 (enExample)
EP (1) EP4433596A4 (enExample)
JP (1) JP2024545602A (enExample)
WO (1) WO2023091644A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CR20210395A (es) 2018-12-21 2021-11-05 Ionis Pharmaceuticals Inc Moduladores de la expresión de hsd17b13
US20240352464A1 (en) * 2023-03-07 2024-10-24 Aligos Therapeutics, Inc. Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof
WO2024255748A1 (zh) * 2023-06-16 2024-12-19 施能康医药科技(苏州)有限公司 靶向17-β-羟基类固醇脱氢酶13的核酸及其用途
WO2025184661A1 (en) * 2024-03-01 2025-09-04 Wave Life Sciences Ltd. Double stranded oligonucleotide compositions and methods relating thereto

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016016400A2 (pt) * 2014-01-16 2017-10-03 Wave Life Sciences Ltd Composições de oligonucleotídeos quiralmente controlados, seu uso, sua composição farmacêutica, e métodos
RU2019126483A (ru) * 2017-01-23 2021-02-24 Ридженерон Фармасьютикалз, Инк. Варианты 17-бета-гидроксистероиддегидрогеназы 13 (hsd17b13) и их применение
JP2020522510A (ja) * 2017-06-02 2020-07-30 ウェイブ ライフ サイエンシズ リミテッドWave Life Sciences Ltd. オリゴヌクレオチド組成物及びその使用方法
EP3728281A1 (en) * 2017-12-21 2020-10-28 Alnylam Pharmaceuticals Inc. Chirally-enriched double-stranded rna agents
AU2019239971B2 (en) * 2018-03-21 2025-09-11 Regeneron Pharmaceuticals, Inc. 17beta-hydroxysteroid dehydrogenase type 13 (HSD17b13) iRNA compositions and methods of use thereof
KR102769565B1 (ko) * 2018-09-19 2025-02-20 애로우헤드 파마슈티컬스 인코포레이티드 17베타-HSD 유형 13- (HSD17B13)의 발현을 억제하기 위한 RNAi 작용제, 그의 조성물, 및 사용 방법
CR20210395A (es) * 2018-12-21 2021-11-05 Ionis Pharmaceuticals Inc Moduladores de la expresión de hsd17b13

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